• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.15 no.2
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• pp.80-103
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• 2002

To screen the effective materials for hair loss treatment, several natural extracts were tested using in vivo and in vitro test models. Firstly, all test materials were applicated onto the back skin of C57BL／6 mouse and then hair growth pormoting effect were measured using hair growth index As a result, Polygonum muitifiorum Thunb and Terrninalia chebula Retz. showed potent hair growth promoting effect, ranking as 1.5-2.0 of hair growth index. However, there were no plant extracts, which have remarkable potential of growth promotion of human hair dermal papilla cells cultured in vitro. In the experiments of 5${\alpha}$-reductase type Ⅱ inhibition assay, Morus alba L., Chaenomelis Fructus, Saussureae Radix, Angelicae Gigantis Radix, Polygonum multifiorum Thunb, and Angelica dahurica (Fischer) Bentham et Hooker f. showed effective potential to inhibit the activity of 5${\alpha}$-reductase type Ⅱ. To investigate the possible involvement of effects of several plant extracts on the gene expression of growth factors in human hair dermal papilla cells, RT-PCR analyses were performed. As a consequences, Mentha haplocalyx Briq., Cimicifuga foetida L., Eclipta prostrata (L.) L., Pinus densiflora S. et. Z, and Polygonum muitifiorum Thunb revealed the regulatory roles on the expression of growth factors such as IGF-I, KGF, HGF and VEGF in the dermal papilla cells. Another test for inhibition of microbial such as P. acne and P. ovale were also carried out to find whether these plant extracts have anti-microbial activities. Morus alba L. and Chaenomelis Fructus showed anti-microbial effects on Propionibacterium acnes, which is believed as a pathogen of acne. Together, these results showed several plant extracts can be used for hair growth promotion.

• Journal of Environmental Health Sciences
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• v.21 no.3
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• pp.38-47
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• 1995

The Bioconcentration factor (BCF) is used as an important criterion in the risk assessment of environmental contaminants. Also it can be used as indicator of biomagnification of environmentally hazardous chemicals through food-chain as well as a tool for ranking the bioconcentration potential of the chemicals in the environment. This paper reports the measured BCF value on Chlorothalonil in Carassius auratus(goldfish), under steady state, and examined correlation between the BCF value and the partition coefficient or acute toxicity or physicochemical properties. Carassius auratus(goldfish) was chosen as test organism and test period were 3-day, 5-day. Experimental concentrations were 0.005, 0.01 and 0.05 ppm. Chlorothalonil in fish tissue and in test water were extracted with n-hexane and acetonitrile. GC-ECD was used to detecting and quantitating of Chlorothalonil. Partition coefficient was determined by stir-flask method. $LC_{50}$ was determined on Chlorothalonil. Carbaryl and BPMC. The obtained results were as follows. 1. It was possible to determine short term BCFs of Chlorothalonil through relatively simple procedure in environmental concentrations. 2. $BF_3$ of Chlorothalonil in concentration of 0.005, 0.01 and 0.05 ppm were 2.1866$\pm$0.23446, 3.5269$\pm$0.23517, 10.2045$\pm$0.18053 and BCFs were 6.6543$\pm$0.55257, 6.9774$\pm$0.02500, 23.4576$\pm$2.06884, respectively. 3. Chlorothalonil concentration in fish extract and BCFs of Chlorothalonil were increased as increasing test concentration and prolonging test period. 4. Fate of test-water concentration on Chlorothalonil was greater than that of control-water con-centration. It is considered that greater fate of test-water concentration on Chlorothalonil is due to hydrolyzing nitrile group under the mild condition and substituting chloro group by some aromatic compounds in test water. 5. Determined logP of Chlorothalonil was 2.80. And determined $LC_{50}$ of Chlorothalonil in time of 24, 48, 72 and 96 hr were 0.1684, 0.1402, 0.1400, 0.1352(mg/l) respectively. And $LC_{50}$ of Carbaryl in above times were 19.918, 18.635, 18.466, 18.12(mg/l) respectively. $LC_{50}$ of BPMC were 10.248, 9.166, 9.087, 8.921(mg/l) respectively. 6. It is suggested that the BCF of Carbamates depend on partition coefficients. But BCF of Chlorothalonil, organochlorine pesticide, would be strongly influenced by steric, electronic effect of substituents than partition coefficient.

• Asian-Australasian Journal of Animal Sciences
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• v.19 no.12
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• pp.1696-1701
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• 2006

A random regression model was applied for the first time for the analysis of test day records and to study the genetic persistency of first lactation milk yield of Indian Murrah buffaloes. Wilmink's Function was chosen to describe the shape of lactation curves. Heritabilities of test day milk yield varied from 0.33 to 0.58 in different test days. The highest heritability was found in the initial test day ($5^{th}$ day) milk yield. Genetic correlations among test day milk yields were higher in the initial test day milk yield and decreased when the test day interval was increased. The magnitude of genetic correlations between test day and 305 day milk yield varied from 0.25 to 0.99. The genetic persistencies of first lactation milk yield were estimated based on daily breeding values using two methods. $P_1$ is the genetic persistency estimated as a summation of the deviation of estimated daily breeding value on days to attain peak yield from each day after days to attain peak yield to different lactation days. $P_2$ is the genetic persistency estimated as the additional genetic yield (gained or lost) from days to attain peak yield to estimated breeding value on different lactation days relative to an average buffalo having the same yield on days to attain peak yield. The mean genetic persistency on 90, 120, 180, 240, 278 and 305 days in milk was estimated as -4.23, -21.67, -101.67, -229.57, -330.06 and -388.64, respectively by $P_1$, whereas by $P_2$ on same days in milk were estimated as -3.96 (-0.32 kg), -23.94 (-0.87 kg), -112.81 (-1.96 kg), -245.83 (-2.81 kg), -350.04 (-3.28 kg) and -407.58 (-3.40 kg) respectively. Higher magnitude of rank correlations indicated that the ranking of buffaloes based on their genetic persistency in both methods were similar for evaluation of genetic persistency of buffaloes. Based on the estimated range of genetic persistency three types of genetic persistency were identified. Genetic correlations among genetic persistency in different days in milk and between genetic persistencies on the same day in milk were very high. The genetic correlations between genetic persistency for different days in milk and estimated breeding value for 305 DIM was increased from 90 DIM to 180 DIM, and highest around 240 DIM which indicates a minimum of 240 days as an optimum first lactation length might be required for genetic evaluation of Indian Murrah buffaloes.

• The Korean Journal of Applied Statistics
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• v.29 no.7
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• pp.1411-1419
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• 2016

Nonparametric procedures in randomized block design was proposed by Friedman (1937) as a general alternative. This method is used to find out the difference in treatment effect. It can cause a loss of inter block information using the ranking in each block. This paper proposed nonparametric procedures using an aligned method proposed by Hodges and Lehmann (1962) to reduce block information based on joint placement suggest by Jo and Kim (2013) in a randomized block design. We also compared the power of the test of the proposed procedures and established method through a Monte Carlo simulation.

• Journal of Navigation and Port Research
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• v.29 no.10 s.106
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• pp.897-906
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• 2005

The purpose of this research is to verify the strategic fitness and relevance of the distribution park for a hub port in Northeast Asia and to find a method to be a hub-port with a competitive edge. The strategic factor of distribution park development are policy, methodology and promotion method So these factors are analysed by structural equation model. The essential results of the research show that distribution park should be actually developed to produce value-added and to be port cluster.

• Korean Journal of Cognitive Science
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• v.6 no.3
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• pp.65-81
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• 1995

Compound nouns as a composition of multiple nouns exhibit diverse occurence patterns in the texts and have varying degree of meaning coherence.The problem of compound nouns in information retrieval is to find a method to represent and identify the compositive patterns of each words.This paper explains how the cooccurrence patterns are related with the meaning of each compound noun and the information of such relations that can be mechanically acquired from texts is used in ranking the candidated documents for a given query.The main theme of the paper is that compound nouns can be categorized according to their occurrence patterns of simple nouns and these occurrence patterns can be formalized by statistical analysis without large dictionary or complex compositive rules.Our suggested model achieved about 7.75% improvement over the best precision of the other methods at each recall measurements on Korean test collection.

• Journal of Korean Society of Rural Planning
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• v.10 no.4 s.25
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• pp.9-18
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• 2004

The purpose or this study is to simulate spatially the urban expansion phenomena with a cellular automata (CA) technique using GIS. A study area, Suwon city, was selected for test of model verification and application with the classified land-use maps of three data years: 1986, 1996, and 2000. The urbanized potential maps were generated with seven criteria of one geographic factor (slope of land), and six accessibility factors (time distances from city, national road, Seoul, station, and built-up boundary), considering their weighting values, which were optimized by WSM (weighted scenario method for intensity order) combined a ranking method and a AHP technique. The optimized weighting values at the urban expansion between 1986 and 1996 were applied to verify the CA model for the other expansion between 1996 and 2000. The results of model application showed that urban sprawl phenomena of the urban expansion toward rural area can be simulated spatially and temporally with several boundary conditions considering various scenarios for the criteria and parameters of the model. Ultimately, this study can contribute to reference data for land-use planning of urban fringe areas.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• v.29 no.1
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• pp.465-470
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• 2005

The purpose of this research is to verify the strategic fitness and relevance of the distribution park for hub port in Northeast Asia and to find a method to be a hub-port with a competitive edge. The Strategic factor of distribution park development are policy, methodology and promotion method. So these factors are analysed by structural equation model. The essential results of the research show that distribution park should be actually developed to product value-added and connected to industry park to be port cluster.

• Science of Emotion and Sensibility
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• v.7 no.1
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• pp.51-64
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• 2004

In this paper, we propose a web page retrieval system based on the sensibility evaluation induced by the color combination of web pages. The realized system consist of two modules - the indexing module that automatically extracts and indexes the color information from the web page and the retrieval module that retrieves web pages based on the color combination when sensibility adjective is presented. Also, to verify the system usefulness, we analyzed the ranking of web pages retrieved by the system and by human subjects (non-expels and experts for color web page design) using two statistical methods of correlation and paired-t test. Results by non-experts showed the realized system was suitable for 10 sensibility adjectives among 18 sensibility adjectives, and results by experts showed that the realized system was suitable for 14 sensibility adjectives among 18 sensibility adjectives.

• The Korean Journal of Applied Statistics
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• v.30 no.2
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• pp.291-299
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• 2017

Mack and Skillings (1980) proposed nonparametric procedures in a randomized block design with replications as general alternatives. This method is used to find the difference in the treatment effect; however, it can cause a loss of inter block information using the ranking in each block. In this paper, we proposed new nonparametric procedures in a randomized block design with replications using an aligned method proposed by Hodges and Lehmann (1962) that used information of blocks and based on the joint placement suggest by Chung and Kim (2008). We also compared the power of the test of the proposed procedures and established a method through Monte Carlo simulation.