• Molecules and Cells
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• 제28권6호
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• pp.583-588
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• 2009

The peroxiredoxin family of peroxidase has six mammalian members (Prx 1-6). Considering their frequent up-regulation in cancer cells, Prxs may contribute to cancer cells' survival in face of oxidative stress. Here, we show that Prx 6 promotes the invasiveness of lung cancer cells, accompanied by an increase in the activity of phosphoinositide 3-kinase (PI3K), the phosphorylation of p38 kinase and Akt, and the protein levels of uPA. Functional studies reveal that these components support Prx 6-induced invasion in the sequence p38 kinase/PI3K, Akt, and uPA. The findings provide a new understanding of the action of Prx 6 in cancer.

• 대한방사선기술학회지:방사선기술과학
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• 제47권4호
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• pp.255-262
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• 2024

Although a universally accepted definition of artificial intelligence (AI) remains elusive, the terminology has gained widespread familiarity owing to its pervasive integration across diverse domains in our daily lives. The application of AI in healthcare, notably in radiographic imaging, is no longer a matter of science fiction but a reality. Consequently, AI education has emerged as an indispensable requirement for radiological technologists responsible for the field of radiology. This paper underscores this imperative and advocates for the incorporation of AI education, using the Orange platform in university radiology department as part of the solution. Furthermore, this paper presents a case study featuring machine learning analysis using structured data on exposure doses for radiation related workers and unstructured data consisting of X-ray data encompassing 69 COVID-19-infected cases and 25 individuals with normal findings. The emphasized importance of AI education for radiology professionals in this research is expected to contribute to the job stability of radiologic practitioners in the future.

• 대한방사선기술학회지:방사선기술과학
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• 제24권2호
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• pp.59-64
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• 2001

The purpose of this study was to examine the general health status of radiological technologists by using Todai Health Index(THI) that has been employed as a standard health assessment tool for a specific group. The subjects in this study were 800 radiological technologists who were working in clinics, hospitals and university hospitals in and around Seoul and in some provincial cities. A survey was conducted directly or by mail in June and July, 2001. And the response rate was 68%. Using THI, the following findings were acquired: 1. By gender, both male and female radiological technologists complained about multiple subjective symptom(I) the most. And the women made more significant complaint of eight items including irregular life. 2. By age group, the radiological technologists whose age ranged from 20 to 24 got higher marks in most of the items, including multiple subjective symptom(I) and symptoms related to eyes and skin. 3. For career, those who had worked for a year or less or for one to five years got higher marks in most of the items. 4. Concerning marital status, the unmarried people complained about many items more, and the married people's symptom was more associated with live scale(L). 5. By the type of medical institution, the radiological technologists in the university hospitals got higher marks in two items including aggressiveness(F), but those in the clinics complained about the others more. 6. Regarding a place of service, there were little differences between the radiological technologists in basement and on the ground.

• Investigative Magnetic Resonance Imaging
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• 제17권1호
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• pp.8-18
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• 2013

목적: 척추전이의 자기공명영상 소견들 중 특정 원발성 암에 특이적인 소견들이 있는지 알아보고자 한다. 대상과 방법: 본 연구에서는 자기공명영상을 시행한 총 169개의 척추전이암 병변들 (56개는 폐암, 29개는 유방암, 20개는 대장암, 17개는 간세포암, 그리고 47개는 위암으로부터 기원)을 후향적으로 분석하였다. 각 병변의 크기, 위치, 침범 정도, 신호강도, 경계, 조영증강 양상, 그리고 골융해/골경화 특성들을 분석하여 원발성 암의 기원에 따라 차이가 있는지 보았다. 결과: 간세포암의 전이 병변들은 대장암을 제외하고는 (P=0.268) 다른 암에 비하여 크기가 유의하게 컸다 (P < 0.05). 경계가 좋은 병변은 폐암과 유방암에서 기원한 경우에서 더 흔히 관찰되었다 (P < 0.01). 간세포암을 제외한 모든 암에서 전이를 할 때 척추의 후부요소보다 척추체를 더 자주 침범하였다(P < 0.02). 대장암과 간세포암은 골외 침범을 더 자주 보였으나 통계학적 의미는 없었다 (P > 0.05). 간세포암과 위암의 전이병변들은 특징적인 조영증강 양상을 보였다. 결론: 일부 자기공명영상 소견들은 척추전이 병변이 어떤 원발성 암에서 기원한 것이지 예측하는 데 도움이 될 수 있다.

• 대한핵의학회지
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• 제39권6호
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• pp.456-463
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• 2005

목적: FDG PET에서 위(stomach)에 보이는 다양한 FDG 섭취 양상들이 임상적으로 어떠한 의미가 있는지 알아보고 유의한 병변의 특징적 양상을 밝혀 내어 좀 더 정확한 PET 판독을 유도하여 임상적 처치에 도움이 되고자 하였다. 대상 및 방법: 2003년 6월에서 2004년 8월까지, 15개월 동안 FDG PET과 위 내시경을 모두 시행한 위 절제술을 받지 않은 피검자들 중에서 두 검사간 간격이 1주일 이내인 총 38명을 대상으로 하여 후향적으로 연구하였다. PET 영상의 분석은 섭취 정도의 측면에서 시각적 섭취 정도와 max.SUV를 사용하였고, 섭취 모양의 측면에서 국소적, 미만성, 비대칭성의 섭취 양상을 인자로 분석하였다. 내시경 소견은 악성 병변, 염증성 병변, 비염증성 병변, 정상 소견으로 분류하였고, 염증성 병변은 다시 궤양, 위염(만성위염, 기타위염)으로 분류하였다. 통계적 분석은 t-test와 Mann Whitney test를 이용하였다. 결과: 악성 병변의 경우 시각적 섭취 정도에서 grade 4,5, max.SUV $7.95{\pm}4.38$로 높은 섭취 정도를 보였으며, 섭취 양상은 국소적 섭취 양상이었다. 이러한 기준에 따른 결과는 다른 병변들과 유의한 차이를 보였다. 염증성 병변, 비염증성 병변, 정상 소견에서는 시각적 섭취 정도가 grade$1{\sim}5$까지 다양하게 분포하였으며, 섭취 양상도 국소적, 미만성, 비대칭적인 다양한 양상이었다. 이러한 양성 염증성 병변, 비염증성 병변, 정상 소견 병변들 간에는 섭취 정도와 양상의 인자들 사이에 유의한 차이를 보이지 않았다. 결론: 위의 악성 병변은 양성 병변에 비해 높은 FDG 섭취 정도를 보이고 섭취 양상에 있어서는 대개가 국소적 섭취 양상이었다. 그러나 위의 양성 병변과 정상에서는 다양한 정도의 섭취 정도와 섭취 양상을 보여 주었고, 각 병변들간에 또는 정상의 생리적 섭취와 구별할 수 있는 소견은 제시하기 어려웠다.

• Journal of Korean Neurosurgical Society
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• 제38권2호
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• pp.147-150
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• 2005

Cavernous angiomas of the cranial nerves are rarely reported. We report a case of a 33-year-old man affected by a cavernous angioma originated in the oculomotor nerve with it's palsy. Preoperative radiological findings are difficult to differentiate it from meningioma or neurinoma. Postopertive pathological report discloses it as cavernous angioma. We discuss radiological, pathological features and management of this vascular lesion of the cranial nerve.

• Investigative Magnetic Resonance Imaging
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• 제24권1호
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• pp.51-54
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• 2020

Superficial siderosis is attributed to hemosiderin deposition in the subpial layers of the nervous system. The clinical features of infratentorial superficial siderosis (ISS) are hearing loss, cerebellar ataxia, and corticospinal tract signs and the most common cause of idiopathic ISS is a dural defect. As magnetic resonance imaging (MRI) has advanced, the diagnosis of infratentorial superficial siderosis can be confirmed by unique radiological findings in MRI. Here, we report on a female patient diagnosed with idiopathic ISS by means of clinical symptoms and radiological findings.

• Tuberculosis and Respiratory Diseases
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• 제44권5호
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• pp.1194-1197
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• 1997

Radiological criteria such as smooth, sharply defined interface, obtuse angles between lesion and lung and intimate effect on mediastinal contents were usually used to differentiate mediastinal lesion from parenchymal lung lesion. Recently, we experienced a 60-year-old female presenting with anterior mediastinal mass with cavitation. Grossly it was proven to be peripheral lung cancer adjacent to mediastinum and microscopically it was squamous cell carcinoma. The gross pathological findings of surgical specimen were very well correlated with radiological findings. The unique location such as lung periphery and attachment to mediastinum led us to misdiagnosis of anterior mediastinal mass such as germ-cell tumor and neurogenic tumor.

• 대한치과의사협회지
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• 제55권7호
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• pp.481-488
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• 2017

The aim of this study is to examine the incidence of odontogenic tumors and to review the clinical and radiological findings for the most frequent three types in Korea. Odontoma, ameloblastoma and keratocystic odontogenic tumors are the most frequent odontogenic tumors in Korea. We provide an overview of these tumors based on clinical and radiographic findings.

• Tuberculosis and Respiratory Diseases
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• 제58권6호
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• pp.543-553
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• 2005

Radiological analysis of chest lesions detected on chest radiographs or CT scans begins with their classification into parenchymal, pleural, or extrapleural lesions according to their presumed origin. The mediastinum is divided anatomically into the anterior, middle, and posterior mediastinal compartments, and localizing a mediastinal mass to one of these divisions can facilitate their differential diagnosis. A differential diagnosis of a mediastinal mass is usually based on a number of findings, including its location; the structure from which it is arising; whether it is single, multifocal (involving several different areas or lymph node groups), or diffuse; its size and shape; its attenuation (fatty, fluid, soft-tissue, or a combination of these); the presence of calcification along with its characteristics and amount; and its opacification following the administration of contrast agents.