• 한국의학물리학회:학술대회논문집
• /
• 한국의학물리학회 2002년도 Proceedings
• /
• pp.294-297
• /
• 2002

For the quality control procedure of diagnostic x ray units, a method for simultaneous measurement of air kerma, half value layer and tube potential was developed utilizing a computed radiography system for intraoral radiography and film badge case. The response of average pixel values under the windows were calibrated by x rays generated at tube potentials from 40 to 140 kV with filtration from 1.5 to 3.7 mmAl. The calibration curves for half value layer and tube potential were derived as functions of attenuation factors by the 1.4 mmAl filter and the 0.2 mmCu filter. The energy dependency of the open window response was corrected by the calibration factor as a function of the attenuation factor by the 1.4 mmAl filter. The uncertainty of the estimated half value layer, tube potential and air kerma were 0.2 mmAl, 3.6 % and 5 %, respectively. It was thus suggested that this system could be applied to quality control program to detect the variation of working condition of x ray units in clinical use.

• Journal of Korean Neurosurgical Society
• /
• 제29권3호
• /
• pp.317-323
• /
• 2000

Objective : To evaluate the role of stereotactic LINAC radiosurgery in treatment of meningiomas, the authors retrospectively analyzed the result of radiosurgery in our institute. Method: During last ten years, twenty patients underwent stereotactic LINAC radiosurgery(LINAC SRS) for meningiomas. The mean age of the patients was 51 years(22-78 years). The most common tumor location for radiosurgery was parasagittal, sphenoid wing and tentorial area. With regards to indications of radiosurgery for meningiomas, LINAC radiosurgery was done for primary treatment in six patients, for postoperative residual tumors in eleven patients, for postoperative regrowth in three patients. Mean tumor volume was $5.14cm^3$($0.28-15.1cm^3$), mean field diameter was 2.01cm(1.2-3cm). The mean marginal dose was 20.55Gy(13-30Gy). The follow-up evaluation was done annually with radiologic findings and clinical status. The mean follow-up period was 46.8(24-120) months. Result : In the radiologic response, the tumor volume was reduced in five(25%) of twenty patients, fourteen showed arrested growth(70%), but one patient showed increased growth(5%). In the clinical response, nine patients improved clinically(45%), ten patients was stable(50%) and one patient worsened during follow-up period. With regards to correlation with radiologic and clinical response, in nineteen patients who showed radiologic response to radiosurgery(decreased and arrested growth after radiosurgery), nine patients(47.4%) improved and ten patients (52.6%) showed no change, one patient(5%) had symptomatic radiation necrosis at four years after SRS, which needed craniotomy. Conclusion : The overall control rate of meningiomas with LINAC radiosurgery was 95% in radiologic follow up and 95% clinically. The radiation complication rate was 5%. These results indicate that LINAC radiosurgery can be considered as safe and effective method for meningiomas.

• 대한방사선기술학회지:방사선기술과학
• /
• 제25권1호
• /
• pp.73-76
• /
• 2002

In order to evaluate the exposure to the radiologic technologists from patients who had been administrated with radiopharmaceuticals, we measured the spatial dose rates at 5 cm, 50 cm, and 100 cm from skin surface of patients using an proportional digital surveymeter, both 5 min after injection and right before the studies. In results, the exposure to the technologists in each procedure was small, compared nth the dose limits of the medical workers. However, the dose-response relationships in cancer and hereditary effects, referred to as the stochastic effects, have been assumed linear and no threshold models ; therefore, the exposure should be minimized. For this purpose, the measurements of spatial dose rate distributions were thought to be useful.

• 대한디지털의료영상학회논문지
• /
• 제11권2호
• /
• pp.93-99
• /
• 2009

This conclusion was from the 3rd grade students of radiologic technology of Daegu Health College who already taken the hospital practice. 231 students answer our question and this study used sampling method. The contents of Questionnaire consisted of normal facts of respondent, Training satisfaction, Training Methods, Practice Environment of Hospital, Problem in Practice Hospital, Before and after views, etc. The statistical program SPSS/Win 10.0 version was used to see the results of the survey data used in. The response contents of brief question were separetely checked and clean.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권5호
• /
• pp.2003-2007
• /
• 2015

Background: Elevated serum alpha-fetoprotein (AFP) levels in adults are considered abnormal. This parameter is used mostly in the diagnosis and follow-up of hepatocellular carcinomas and yolk sac tumors. Among the other rare tumors accompanied with elevated serum AFP levels, gastric cancer is the most common. In this study, we evaluated the follow-up and comparison of the treatment and marker response of patients with metastatic gastric cancer who had elevated serum AFP levels. Materials and Methods: We performed a retrospective study, including all consecutive patients with advanced gastric cancer, who received systemic chemotherapy with elevated AFP level. Results: Seventeen metastatic gastric cancer patients with elevated AFP levels at the time of diagnosis were evaluated. Fourteen (82.4%) were males and three (17.6%) were females. The primary tumor localization was the gastric body in 8 (76.4%), cardia in 7 (41.2%), and antrum in 2 (11.8%). Hepatic metastasis was observed in 13 (76.4%) at the time of diagnosis. When the relationship of AFP levels and carcinoembryonic antigen (CEA) response of the patients with their radiologic responses was evaluated, it was found that the radiologic response was compatible with AFP response in 16 (94.1%) patients and with CEA response in 12 (70.6%); however, in 5 (29.4%) patients no accordance was observed between radiological and CEA responses. Conclusions: Follow-up of AFP levels in metastatic gastric cancer patients with elevated AFP levels may allow prediction of early treatment response and could be more useful than the CEA marker for follow-up in response evaluation.

• 디지털콘텐츠학회 논문지
• /
• 제16권3호
• /
• pp.463-470
• /
• 2015

최근 개인선량계로 사용이 증가하고 있는 수동형 선량계인 OSLD와 능동형 선량계인 EPD의 상대 반응도(relative response), 측정 불확도(uncertainty of measurement)를 계산하여 방향의존성(angular dependence)을 비교, 분석하였다. OSLD는 수평, 수직방향의 $0^{\circ}{\sim}{\pm}90^{\circ}$ 범위에서 평균 상대 반응도는 0.97, 0.95의 작은 변화를 보였고 방향의존성에 대한 불확도는 0.65, 0.62로 전체 불확도에 미치는 영향은 미미한 것으로 판단되었다. EPD는 $0^{\circ}{\sim}{\pm}60^{\circ}$ 범위에서 수평, 수직방향 평균 상대 반응도는 0.94, 0.97로 확인되어 IEC 61526 규정을 만족하였다. 방향의존성에 대한 불확도는 수평, 수직방향에서 0.44, 0.40로 전체 불확도에 미치는 영향은 미미하였다. 그러나 수평방향에서 $+90^{\circ}$, $-90^{\circ}$ 방향의 상대 반응도는 0.60, 0.37이고 수직방향에서 $+90^{\circ}$ 방향의 반응도는 0.06으로 반응도의 큰 변화를 관찰할 수 있었다. OSLD의 방향 의존성은 $0^{\circ}{\sim}{\pm}90^{\circ}$ 범위까지 EPD에 비해 우수하였으며 EPD의 경우 구조적 특징으로 반응도가 급변하는 특정방향이 존재하였다. 따라서 수동형선량계와 보조선량계의 병행사용이 개인피폭선량측정의 정확도를 기할 수 있을 것으로 판단된다.

• Korean Journal of Radiology
• /
• 제25권6호
• /
• pp.550-558
• /
• 2024

Hepatocellular carcinoma (HCC) is a biologically heterogeneous tumor characterized by varying degrees of aggressiveness. The current treatment strategy for HCC is predominantly determined by the overall tumor burden, and does not address the diverse prognoses of patients with HCC owing to its heterogeneity. Therefore, the prognostication of HCC using imaging data is crucial for optimizing patient management. Although some radiologic features have been demonstrated to be indicative of the biologic behavior of HCC, traditional radiologic methods for HCC prognostication are based on visually-assessed prognostic findings, and are limited by subjectivity and inter-observer variability. Consequently, artificial intelligence has emerged as a promising method for image-based prognostication of HCC. Unlike traditional radiologic image analysis, artificial intelligence based on radiomics or deep learning utilizes numerous image-derived quantitative features, potentially offering an objective, detailed, and comprehensive analysis of the tumor phenotypes. Artificial intelligence, particularly radiomics has displayed potential in a variety of applications, including the prediction of microvascular invasion, recurrence risk after locoregional treatment, and response to systemic therapy. This review highlights the potential value of artificial intelligence in the prognostication of HCC as well as its limitations and future prospects.

• The Korean Journal of Pain
• /
• 제2권2호
• /
• pp.198-202
• /
• 1989

우측 암면부, 특히 안구주위에 심한 통증을 호소하고 안검하수와 더불어 우측안구의 완전마비를 동반한 선천성 난장이 환자를 경험하였던 바 이는 신경방사선과학적소견, 검사실 검사소견, 전신적 corticosteroid치료에 대한 반응이 전형적인 Tolosa-Hunt Syndrome과는 다른 비전형적인 Tolosa-Hunt Syndrome이었기에 문헌적 고찰과 함께 보고하는 바이다.

• 대한방사선기술학회지:방사선기술과학
• /
• 제35권4호
• /
• pp.309-314
• /
• 2012

Digital Radiography(DR) 시스템은 임상현장에서 아날로그 시스템을 대체하고 널리 이용되고 있다. DR을 이용하여 얻어진 X선 영상의 해상력을 결정짓는 요소에는 이용되는 검출기의 고유 해상력, 피사체의 대조도 및 특성, X선 선질, X선원의 산란, DR 검출기의 성능, X선 변환효율 및 초점의 크기, 피사체의 움직임 등이 있다. DR 검출기를 구성하는 요소에는 X선 포획 요소, 커플링 요소, 정보수집 요소가 있는데 이들은 시스템의 성능에 영향을 미치며, 그 성능은 해상력으로 평가된다. 의료영상 시스템의 해상력은 촬영대상물의 조직 간의 해부학적 영상을 구분하는 능력을 나타낸다. 해상력 평가를 위해 Modulation Transfer Function(MTF)이 보편적으로 이용되고, MTF는 입력 공간주파수 성분에 대한 출력 공간주파수 성분의 비를 나타내는데, 수학적으로 MTF는 Point Spread Function(PSF) 입력에 대한 시스템의 주파수 응답이며 Edge Phantom을 이용한 결과 영상에서 추출된 Line Spread Function(LSF)을 Fourier Transform하면 얻을 수 있다. 일반적으로 임상현장에서 의료영상시스템의 이용 및 관리의 책임은 방사선사가 맡고 있지만, MTF를 측정하기 위해서는 공학적, 수학적 기초 및 C, Fortran, Matlab등의 프로그램 작성 능력이 필요하기 때문에 비 공학도는 정확한 측정이 불가능하다. 의료영상 시스템의 성능 관리 및 최상의 상태를 유지하기 위해 시스템의 성능평가가 이뤄져야 하는데, 이를 위해 본 연구에서는 비공학도가 해상력 성능평가를 할수 있도록 ImageJ 및 Excel을 이용하여 해상력 평가를 할 수 있도록 방법을 제시하고, 제안된 방법을 이용해 계산된 결과와 프로그래밍을 이용해 계산된 결과의 비교를 통해 본 논문에서 제시하는 방법의 유용성을 확인하였다.

• Journal of Korean Neurosurgical Society
• /
• 제55권1호
• /
• pp.5-11
• /
• 2014

Objective : We evaluated pseudoprogression (PsPD) following radiation therapy combined with concurrent temozolomide (TMZ), and we assessed pseudoresponse following anti-angiogenic therapy for patients with recurrent disease using the Response Assessment of the Neuro-Oncology Working Group. Methods : Patients who were pathologically confirmed as having high-grade glioma received radiotherapy with concurrent TMZ followed by adjuvant TMZ. Bevacizumab (Avastin) with CPT-11 were used as a salvage option for cases of radiologic progression. Magnetic resonance imaging (MRI) was routinely performed 1 month after concurrent radiochemotherapy (CRT) and every 3 months thereafter. For cases treated with the bevacizumab-containing regimen for progressive disease, MRI was performed every 2 months. Results : Of 55 patients, 21 (38%) showed radiologic progression within 4 weeks after CRT. Of these patients, 16 (29%) showed progression at second post-CRT MRI (etPD) and five (9%) showed improvement (PsPD). Seven of thirty-four initially non-progressed patients showed progression at the second post-CRT MRI (ltPD). No difference in survival was observed between the etPD and ltPD groups (p=0.595). Five (50%) of ten patients showed a radiological response after salvage bevacizumab therapy. Four of those patients exhibited rapid progression immediately after discontinuation of the drug (drug holiday). Conclusion : Twelve weeks following treatment could be the optimal timing to determine PsPD or true progression. MRI with gadolinium enhancement alone is not sufficient to characterize tumor response or growth. Clinical correlation with adequate follow-up duration and histopathologic validation may be helpful in discriminating PsPD from true progression.