• Journal of Korean Neurosurgical Society
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• v.60 no.1
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• pp.15-20
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• 2017

Objective : Diagnosing tumor progression and pseudoprogression remains challenging for many clinicians. Accurate recognition of these findings remains paramount given necessity of prompt treatment. However, no consensus has been reached on the optimal technique to discriminate tumor progression. We sought to investigate the role of magnetic resonance perfusion (MRP) to evaluate tumor progression in glioma patients. Methods : An institutional retrospective review of glioma patients undergoing MRP with concurrent clinical follow up visit was performed. MRP was evaluated in its ability to predict tumor progression, defined clinically or radiographically, at concurrent clinical visit and at follow up visit. The data was then analyzed based on glioma grade and subtype. Resusts : A total of 337 scans and associated clinical visits were reviewed from 64 patients. Sensitivity, specificity, positive and negative predictive value were reported for each tumor subtype and grade. The sensitivity and specificity for high-grade glioma were 60.8% and 87.8% respectively, compared to low-grade glioma which were 85.7% and 89.0% respectively. The value of MRP to assess future tumor progression within 90 days was 46.9% (sensitivity) and 85.0% (specificity). Conclusion : Based on our retrospective review, we concluded that adjunct imaging modalities such as MRP are necessary to help diagnose clinical disease progression. However, there is no clear role for stand-alone surveillance MRP imaging in glioma patients especially to predict future tumor progression. It is best used as an adjunctive measure in patients in whom progression is suspected either clinically or radiographically.

• Journal of the Institute of Electronics and Information Engineers
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• v.52 no.11
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• pp.127-134
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• 2015

Tissue stimulation technique using ultrasound has been continuously studied and developed. Recently, as a increment of interests for obesity treatment and cosmetic care, a various studies on ultrasonic fat emulsification has been conducted. In this study, the fat emulsification adapted ultrasonic transducer was designed. And using designed transducer, the simulation for the shape of focal area and thermal degradation region was conducted. The dimensions were verified by the simulation results. And the effectiveness was confirmed by evaluating measured radiation characteristic and heating characteristic. In addition, we estimated the ultrasonic heating characteristics in composite structure medium. The shape of focal point and heating characteristic of the proposed transducer were determined to be sufficient to emulsify the fat. The results of this study are considered to be used as basic research in more efficient and safe ultrasonic fat removal.

• Advances in materials Research
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• v.2 no.2
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• pp.77-91
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• 2013

High quality nanoparticles of neodymium barium niobium ($NdBa_2NbO_6$) perovskites have been synthesized using an auto ignition combustion technique for the first time. The nanoparticles thus obtained have been characterized by powder X-ray diffraction, thermo gravimetric analysis, differential thermal analysis, Fourier transform infrared spectroscopy, Raman spectroscopy and transmission electron microscopy. UV-Visible absorption and photoluminescence spectra of the samples are also recorded. The structural analysis shows that the nano powder is phase pure with the average particle size of 35 nm. The band gap determined for $NdBa_2NbO_6$ is 3.9 eV which corresponds to UV-radiation for optical inter band transition with a wavelength of 370nm. The nanopowder could be sintered to 96% of the theoretical density at $1325^{\circ}C$ for 2h. The ultrafine cuboidal nature of nanopowders with fewer degree of agglomeration improved the sinterability for compactness at relatively lower temperature and time. During the sintering process the wide band gap semiconducting behavior diminishes and the material turns to a high permittivity dielectric. The microstructure of the sintered surface was examined using scanning electron microscopy. The striking value of dielectric constant ${\varepsilon}_r=43$, loss factor tan ${\delta}=1.97{\times}10^{-4}$ and the observed band gap value make it suitable for many dielectric devices.

• Korean Journal of Optics and Photonics
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• v.1 no.1
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• pp.46-51
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• 1990

Laser plasma was generated by a 1GW iodine photodissociation laser ($\lambda$=1.315$\mu\textrm{m}$, E=12.7J) whose output beam was focused on a molybdenum target surface. The experiment was conducted in a vacuum chamber under 1D-sTorr and several tens of laser shooting were necessary for sufficient exposure for the PBS resist of 111m thickness. Aluminium was coated on the top of the resist by 0.1$\mu\textrm{m}$ thickness which acts as an X-ray filter to cut off the visible and the ultraviolet lights. A bio-specimen was put directly on the aluminium coated resist and located at a distance of 3 cm from the X-ray source. The replicas of a steel mesh, spider's web. and a red blood cell were obtained by this technique and were observed by Nomarski microscope and SEM. The limitation of its resolution is determined by the X-ray source size and Fresnel diffraction effect, and its theoretical prediction is well matched with the experimental results. In this experiment, a resolution better than 0.1$\mu\textrm{m}$ could be obtained. ained.

• Korean Journal of Breeding Science
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• v.42 no.4
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• pp.365-373
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• 2010

TILLING (Targeting Induced Local Lesions IN Genomes) is broadly regarded as an excellent methodology for reverse genetics applications. Approximately 15,000 $M_3$ TILLING lines have been developed via the application of gamma-ray irradiation to rice seeds (cv. Donganbyeo), followed by subsequent selections. In an effort to evaluate the genetic diversity of the TILLING population, we have employed the AFLP multiple dominant marker technique. A total of 96 (0.64%) TILLING lines as well as Donganbyeo were selected randomly and their genetic diversity was assessed based on AFLP marker polymorphisms using 5 primer combinations. An average of 100.4 loci in a range of 97 to 106 was detected using these primer combinations, yielding a total of 158 (31.4%) polymorphic loci between Donganbyeo and each of the 96 lines. A broad range of similarity from 80% to 96% with an average of 89.4% between Donganbyeo and each of the 96 lines was also observed, reflecting the genetic diversity of the TILLING population. Approximately 28 polymorphic loci have been cloned and their sequences were BLAST-searched against rice whole genome sequences, resulting in 20 matches to each of the gene bodies including exon, intron, 1 kb upstream and 1 kb downstream regions. Six polymorphic loci evidenced changes in the coding regions of genes as compared to the rice pseudomolecules, 4 loci of which exhibited missense mutations and 2 loci of which exhibited silent mutations. Therefore, the results of our study show that the TILLING rice population should prove to be a useful genetic material pool for functional genomics as well as mutation breeding applications.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.6
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• pp.123-128
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• 2020

In this paper, we presents a new cone beam computerized tomography (CBCT) system for the reconstruction of 3 dimensional dynamic images. The system using cone beam has less the exposure of radioactivity than fan beam, relatively. In the system, the reconstruction 3-D image is reconstructed with the radiation angle of X-ray in the image processing unit and transmitted to the monitor. And in the image processing unit, the Three Pass Shear Matrices, a kind of Rotation-based method, is applied to reconstruct 3D image because it has less transcendental functions than the one-pass shear matrix to decrease a time of calculations for the reconstruction 3-D image in the processor. The new system is able to get 3~5 3-D images a second, reconstruct the 3-D dynamic images in real time. And we showed the Rotation-based method was good rather than existing reconstruction technique for 3D images, also found weakness and a solution for it.

• Progress in Medical Physics
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• v.31 no.4
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• pp.179-188
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• 2020

Purpose: We compared noncoplanar volumetric modulated arc therapy (ncVMAT) plans to coplanar VMAT (cVMAT) plans by evaluating the dosimetric quality of each for esophageal cancer. Methods: Twenty patients treated for esophageal cancer with the cVMAT technique were retrospectively selected. The cVMAT plans consisted of three coplanar full arc beams. The ncVMAT plans consisted of two coplanar full arc beams and one noncoplanar partial arc beam ranging from 45° to 315° with a couch rotation angle of 315°±5°. For dosimetric evaluation, the dose-volumetric (DV) parameters of the planning target volume (PTV) and organs at risk (OARs) were calculated for all VMAT plans. Results: No clinically noticeable differences between the cVMAT and ncVMAT plans were observed in the DV parameters of the PTV. For the lungs, the V_{13 Gy} and mean dose for ncVMAT plans were smaller than those for cVMAT plans, showing statistically significant differences. For the heart, the values of the maximum dose for cVMAT and ncVMAT plans were 53.8±2.9 and 50.9±3.3 Gy, respectively (P=0.004). For the spinal cord, the values of the maximum dose for cVMAT and ncVMAT plans were 37.1±5.1 and 34.7±5.7 Gy, respectively (P<0.001). Conclusions: The use of ncVMAT plans provides better PTV coverage and sparing of OARs compared to that of cVMAT plans for long, tube-like esophageal cancer. For esophageal cancer, the ncVMAT plans showed a more favorable plan quality than the cVMAT plans.

• International Journal of Computer Science & Network Security
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• v.21 no.6
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• pp.47-53
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• 2021

The article deals with the problems of application of microwave methods in systems of geoecological monitoring of natural environments and resources of the agro-industrial complex. It is noted that the methods of microwave radiometry make it possible, by the power of the measured intrinsic radio-thermal radiation of the atmosphere, when solving inverse problems using empirical and semi-empirical models, to determine such parameters of the atmosphere as thermodynamic temperature, humidity, water content, moisture content, precipitation intensity, and the presence of different fractions of clouds.In addition to assessing the meteorological parameters of the atmosphere and the geophysical parameters of the underlying surface based on the data of microwave radiometric measurements, it is possible to promptly detect and study pollution of both the atmosphere and the earth's surface. A technique has been developed for the analysis of sources of measurement error and their numerical evaluation, because they have a significant effect on the accuracy of solving inverse problems of reconstructing the values of the physical parameters of the probed media.To analyze the degree of influence of the limited spatial selectivity of the antenna of the microwave radiometric system on the measurement error, we calculated the relative measurement error of the ratio of radio brightness contrasts in two angular directions. It has been determined that in the system of geoecological monitoring of natural environments, the effect of background noise is maximal with small changes in the radiobrightness temperature during angular scanning and high sensitivity of the receiving equipment.

• Korean Journal of Materials Research
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• v.31 no.12
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• pp.657-664
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• 2021

To build a highly active photocatalytic system with high efficiency and low cast of TiO₂, we report a facile hydrothermal technique to synthesize Ag₂Se-nanoparticle-modified TiO₂ composites. The physical characteristics of these samples are analyzed by X-ray diffraction, scanning electron microscopy with energy dispersive X-ray analysis, transmission electron microscopy and BET analysis. The XRD and TEM results show us that TiO₂ is coupled with small sized Ag₂Se nanoplate, which has an average grain size of about 30 nm in diameter. The agglomeration of Ag₂Se nanoparticles is improved by the hydrothermal process, with dispersion improvement of the Ag₂Se@TiO₂ nanocomposite. Texbrite BA-L is selected as a simulated dye to study the photodegradation behavior of as-prepared samples under visible light radiation. A significant enhancement of about two times the photodegradation rate is observed for the Ag₂Se@TiO₂ nanocomposite compared with the control sample P25 and as-prepared TiO₂. Long-term stability of Ag₂Se@TiO₂ is observed via ten iterations of recycling experiments under visible light irradiation.

• Journal of the Korean Society of Radiology
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• v.16 no.1
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• pp.53-59
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• 2022

DEXA, as the standard areal bone mineral density (aBMD) measurement method, often shows an insuficient correlation between aBMDs of the measured bones and referring bones and is inaccurate due to the mass effect. In contrast, quantitative computer tomography (QCT), as a volumetric BMD (vBMD) measurement method, is being advanced so that it uses less radiation before, owing to improved CT device and computer imaging technology. Because dual-energy CTs can modulate the image signals showing tumor or specific chemicals as well as the ability to measure vBMD, they are expanding their application. For pre-checking vBMD of surgeon-specific bone volume at implantation candidate sites, a finite element creation-based local vBMD measurement technique was developed. The local vBMD measurement function for surgeon-specific shape volumes will be added to clinical imaging systems.