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Effect of Dietary Vitamin E on Growth Performance and Immune Response of Breeder Chickens

  • Lin, Y.F.;Chang, S.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.6
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    • pp.884-891
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    • 2006
  • The effect of dietary vitamin E supplementation on immune responses was studied in breeder chickens during the maturing period. In experiment 1, 17-week old female birds were fed corn-soybean meal based diets supplemented with either 0, 40, 80, 120, or 160 mg vitamin E (all-rac-${\alpha}$-tocopherol acetate)/kg diet for 19 weeks. In experiment 2, 23-week old male birds were fed the corn-soybean meal based diet supplemented with either 0, 20, 40, 80 or 160 mg vitamin E/kg diet for 8 weeks. The chickens were evaluated for growth performance, antibody titer to sheep red blood cell (SRBC), Newcastle disease virus (NDV), infectious bursal disease virus (IBDV) and infectious bronchitis virus (IBV), and skin response to phytohemagglutinin-P (PHA-P). The results showed that supplemental vitamin E improved body weigh gain of laying pullets during peak-laying period but had no significant effect on growth performance of cockerels. For cockerels, addition of 20 mg vitamin E/kg diet significantly enhanced (p<0.05) immune response to SRBC compared to those added with 0, 80 and 160 mg vitamin E/kg diet; addition of 20 mg vitamin E/kg diet had higher (p<0.01) antibody titer to IBDV than those added with 40-160 mg vitamin E/kg diet. No significant effects on immune response were observed in laying pullets fed supplemental vitamin E. The findings suggest that moderate supplementation of vitamin E may enhance immune responses to selective antigens in cockerels but excessive vitamin E may depress specific immune response.

Adsorption of Carbon Dioxide using Pelletized AC with Amine impregnation (아민 함침 입자상 활성탄의 특성 분석 및 이산화탄소 흡착능 평가연구)

  • Lim, Yun-Hui;Jo, Young-Min;Kim, Seung-Ho
    • Journal of the Korean Applied Science and Technology
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    • v.30 no.1
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    • pp.88-95
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    • 2013
  • This study attempts to capture the low level carbon dioxide from indoor spaces using a granular activated carbon (WSC-470) which was modified with primary monoethanolamine. Adsorption capacity of the prepared adsorbents was evaluated for pure $CO_2$ flow and 3000 ppm as a function of MEA concentration and solvents such as distilled water, ethanol and methanol. The AC based adsorbents then were characterized in terms of pore structure by BET and chemical functionalities by XPS. While high concentration of MEA reduced specific surface area, porosity and micro pores, nitrogen content which can enhance the surface basicity was increased. The maximum adsorption capacity decreased comparing to the initial AC pellets, whilst the potential of selective adsorption amount at low level $CO_2$ was increased at 45% (0.73 mmol/g).

PRELIMINARY REPORT: DESIGN AND TEST RESULTS OF KSR-3 ROCKET MAGNETOMETERS

  • Kim, Hyo-Min;Jang, Min-Hwan;Lee, Dong-Hun;Ji, Jong-Hyun;Kim, Sun-Mi;Son, De-Rac;Hwang, Seung-Hyun
    • Journal of Astronomy and Space Sciences
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    • v.17 no.2
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    • pp.317-328
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    • 2000
  • The solar wind contributes to the formation of unique space environment called the Earth's magnetosphere by various interactions with the Earth's magnetic field. Thus the solar-terrestrial environment affects the Earth's magnetic field, which can be observed with an instrument for the magnetic field measurement, the magnetometer usually mounted on the rocket and the satellite and based on the ground observatory. The magnetometer is a useful instrument for the spacecraft attitude control as well as the Earth's magnetic field measurements for the spacecraft purpose. In this paper, we present the preliminary design and test results of the two onboard magnetometers of KARI's (Korea Aerospace Research Institute) sounding rocket, KSR-3, which will be launched four times during the period of 2001-02. The KSR-3 magnetometers consist of the fluxgate magnetometer, MAG/AIM (Attitude Information Magnetometer) for acquiring the rocket flight attitude information, and of the search-coil magnetometer, MAG/SIM (Scientific Investigation Magnetometer) for the observation of the Earth's magnetic field fluctuations. With the MAG/AIM, the 3-axis attitude information can be acquired by the comparison of the resulting dc magnetic vector field with the IGRF (International Geomagnetic Reference Field). The Earth's magnetic field fluctuations ranging from 10 to 1,000 Hz can also be observed with the MAG/SIM measurement.

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Degradation Evaluation of 1Cr-lMo-0.25V Steel by Measuring Reversible Magnetic Permeability (가역 투자율 측정에 의한 1Cr-1Mo-0.25V 강의 열화도 평가)

  • Ryu, Kwon-Sang;Kim, Yong-Il;Nahm, Seung-Hoon;Yu, Kwang-Min;Cho, Youk;Son, De-Rac
    • Journal of the Korean Society for Nondestructive Testing
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    • v.20 no.5
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    • pp.445-450
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    • 2000
  • The integrity of the turbine rotors can be assessed by measuring reversible permeability and Vickers hardness of the aged rotors at service temperature. The measurement system of reversible permeability, which measured by applied alternating perturbing magnetic field, was constructed in order to evaluate material degradation, nondestructively. The test specimen was 1Cr-1Mo-0.25V steel used widely for turbine rotor material, and the specimens were prepared by the isothermal heat treatment at $630\;^{\circ}C$. The reversible permeability of the test materials were measured at room temperature. The peak interval of reversible permeability and Vickers hardness decreased with the increase of degradation. The degradation of test material may be determined nondestructively by the lineality of Vickers hardness and the peak interval of reversible permeability.

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2-(Trimethylammonium) Ethyl (R)-3-Methoxy-3-oxo-2-Stearamidopropyl Phosphate Suppresses Osteoclast Maturation and Bone Resorption by Targeting Macrophage-Colony Stimulating Factor Signaling

  • Park, So Jeong;Park, Doo Ri;Bhattarai, Deepak;Lee, Kyeong;Kim, Jaesang;Bae, Yun Soo;Lee, Soo Young
    • Molecules and Cells
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    • v.37 no.8
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    • pp.628-635
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    • 2014
  • 2-(Trimethylammonium) ethyl (R)-3-methoxy-3-oxo-2-stearamidopropyl phosphate [(R)-TEMOSPho], a derivative of an organic chemical identified from a natural product library, promotes highly efficient megakaryopoiesis. Here, we show that (R)-TEMOSPho blocks osteoclast maturation from progenitor cells of hematopoietic origin, as well as blocking the resorptive function of mature osteoclasts. The inhibitory effect of (R)-TEMOSPho on osteoclasts was due to a disruption of the actin cytoskeleton, resulting from impaired downstream signaling of c-Fms, a receptor for macrophage-colony stimulating factor linked to c-Cbl, phosphoinositol-3-kinase (PI3K), Vav3, and Rac1. In addition, (R)-TEMOSPho blocked inflammation-induced bone destruction by reducing the numbers of osteoclasts produced in mice. Thus, (R)-TEMOSPho may represent a promising new class of antiresorptive drugs for the treatment of bone loss associated with increased osteoclast maturation and activity.

Construction of 3-Axis Flux-gate Magnetometer for Attitude Control of Satellite (인공위성의 자세제어용 3-축 Flux-gate 마그네토미터 제작)

  • Son, De-Rac
    • Journal of the Korean Magnetics Society
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    • v.16 no.3
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    • pp.182-185
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    • 2006
  • In this work, we have constructed 3-axis flux-gate magnetometer for the attitude control of satellite. The constructed magnetometer shows uncertainty of ${\pm}1%$, noise level of $0.2nT/\sqrt{Hz}$ at 1 Hz under 1W power consumption. Environment test for satellite component, acceleration test and thermal cycle test were carried out. For the acceleration test, magnetometer was vibrated frequency ranging from 10 Hz to 1 kHz at 15 g (g : gravitational acceleration at earth), and for thermal cycle test, 4 times of thermal cycle were carried out temperature ranging from $-55^{\circ}C\;to\;+80^{\circ}C$ under vacuum of $1x10^{-6}Torr$.

Prevalence of virulence and cytolethal distending toxin (CDT) genes in thermophilic Campylobacter spp. from dogs and humans in Gyeongnam and Busan, Korea

  • Cho, Hyun-Ho;Kim, Sang-Hyun;Min, Wongi;Ku, Bok-Kyung;Kim, Yong-Hwan
    • Korean Journal of Veterinary Research
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    • v.54 no.1
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    • pp.39-48
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    • 2014
  • The prevalence of thermophilic Campylobacter (C.) spp. in stray, breeding, and household dogs was 25.2, 12.0, and 8.8%, respectively. C. jejuni and C. upsaliensis were the predominant Campylobacter spp. from household dogs. cdtA, cdtB, and cdtC were detected by PCR in all isolates. Despite the high cytolethal distending toxin (CDT) gene prevalence, only 26 (31%) C. jejuni strains and one (15.3%) C. coli strain showed evidence of CDT production in HEp-2 cell cytotoxicity assays. Virulence-associated genes detected in the C. jejuni and C. coli isolates were cadF, dnaJ, flaA, racR, ciaB, iamA, pldA, virB11, ceuE, and docC. cadF, dnaJ, flaA, and ceuE were found in all C. jejuni and C. coli isolates. When detecting Guillain-Barr$\acute{e}$ syndrome-associated genes (galE, cgtB, and wlaN), galE was identified in all isolates. However, cgtB and wlaN were more prevalent in C. jejuni isolates from humans than those from dogs. Adherence and invasion abilities of the C. jejuni and C. coli strains were tested in INT-407 cells. A considerable correlation (adjusted $R^2$= 0.678) existed between adherence and invasion activities of the Campylobacter spp. isolates.

Cr(III)-Tetraaza Macrocyclic Complexes Containing Auxiliary Ligands (Part III); Synthesis and Characterization of Cr(III)-Isothiocyanato, -Azido and -Chloroacetato Macrocyclic Complexes

  • Byun, Jong-Chul;Han, Chung-Hun;Park, Yu-Chul
    • Bulletin of the Korean Chemical Society
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    • v.26 no.7
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    • pp.1044-1050
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    • 2005
  • The reaction of cis-[Cr([14]-decane)($OH_2)_2]^+$ ([14]-decane = rac-5,5,7,12,12,14-hexamethyl-1,4,8,11-teraazacyclotetradecane) with auxiliary ligands {$L_a$ = isothiocyanate ($NCS^-$), azide ($N3^-$) or chloroacetate(caa)} leads to a new cis-[Cr([14]-decane)($NCS)_2]ClO_4{\cdot}H_2O$ (1), cis-[Cr([14]-decane)($N_3)_2]ClO_4$ (2) or cis-[Cr([14]-decane)($caa)_2]ClO_4$ (3). These complexes have been characterized by a combination of elemental analysis, conductivity, IR and Vis spectroscopy, mass spectrometry, and X-ray crystallography. Analysis of the crystal structure of cis-[Cr([14]-decane)($NCS)_2]ClO_4{\cdot}H_2O$ reveals that central chromium(III) has a distorted octahedral coordination environment and two $NCS^-$anions are bonded to the chromium(III) ion via the Ndonor atom in the cis positions. The angle $N_{axial}-Cr-N_{axial}$ deviates by 13$^{\circ}$ from the ideal value of 180$^{\circ}$ for a perfect octahedron. The bond angle N-Cr-N between the Cr(III) ion and the two nitrogen atoms of the isothiocyanate ligands is close to 90$^{\circ}$. The bond lengths of Cr-N between the chromium and $NCS^-$groups are 1.964(5) and 2.000(5) $\AA$. They are shorter than those between chromium and nitrogen atoms of the macrocycle. The IR spectra of 1, 2 and 3 display bands at 2073, 1344 and 1684 $cm^{-1}$ attributed to the $NCS^-$, ${N_3}^-$ and caa groups stretching vibrations, respectively.

Flammability and Thermal Stabilities of Heat Transfer Oils (열매체유의 인화성과 열안정성)

  • Lee, Keun-Won;Lee, Jung-Suk;Choi, Yi-Rac
    • Journal of the Korean Institute of Gas
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    • v.15 no.2
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    • pp.82-87
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    • 2011
  • Heat transfer oils are used in applications such as heating systems of chemical plant, refinery heat exchange systems, gas plant process, injection molding systems, and pulp and paper processing. These oils are extremely stable and resistance to thermal and oxidative degradation. In the event of a spill or accidental release of heat transfer oils, it can be ignite easily when there is an ignition source. This paper discusses the flammability and thermal stabilities of new and used oils. The flammability of the oils are assessed by measuring changes in flash point and auto ignition temperature. The thermal stability of oils are evaluated by the thermal screening unit ($TS^u$) and the differential scanning calorimeter (DSC). From the experimental results, it is suggested to give fire hazard characteristics to safe precautions for the proper use and treatment of heat transfer oils.

Actual Condition and Realization of Important on Laboratory Safety Management in Chemical Laboratories (화학물질 사용 실험실의 안전관리 실태와 인식도)

  • Lee, Keun-Won;Choi, Yi-Rac
    • Journal of the Korean Institute of Gas
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    • v.16 no.2
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    • pp.60-66
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    • 2012
  • With diversification of research and development activity according to fusion of state-of-the-art technology, potential hazard and risk factors in new forms have been increased in the laboratories. Also, as there are many cases where the experimental condition is extremely high/low temperature and pressure, many many accidents producing loss of life and/or injuries occur due to the extreme condition. In this study, The common fact questionnaire as the survey tool for the establishment of the accident prevention countermeasure in laboratory have been developed to safety security of the laboratory workers. The current status of chemical materials and the realization of important on laboratory safety management using the questionnaire investigated by an electronic mail and visiting survey in the laboratories and universities. The collected data was analyzed with Excel program and it can be utilized as basic data for accident prevention in laboratories.