• Laboraroty Animal Research
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• v.34 no.4
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• pp.203-210
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• 2018

Stress severely disturbs physiological and mental homeostasis which includes adult neurogenesis in hippocampus. Neurogenesis in hippocampus is a key feature to adapt to environmental changes and highly regulated by multiple cellular signaling pathways. The primary cilium is a cellular organelle, which acts as a signaling center during development and neurogenesis in adult mice. However, it is not clear how the primary cilia are involved in the process of restraint (RST) stress response. Using a mouse model, we examined the role of primary cilia in repeated and acute RST stress response. Interestingly, RST stress increased the number of ciliated cells in the adult hippocampal dentate gyrus (DG). In our RST model, cell proliferation in the DG also increased in a time-dependent manner. Moreover, the analysis of ciliated cells in the hippocampal DG with cell type markers indicated that cells that were ciliated in response to acute RST stress are neurons. Taken together, these findings suggest that RST stress response is closely associated with an increase in the number of ciliated neurons and leads to an increase in cell proliferation.

• Korean Journal of Veterinary Research
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• v.55 no.1
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• pp.31-39
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• 2015

The present study was conducted to determine the full rpoB and eight house-keeping gene sequences of 78 and 35, respectively, avian pathogenic E. coli (APEC) strains. Phylogenetic comparison with 66 E. coli and Shigella strains from GenBank and EMBL was also conducted. Based on the full rpoB sequence, 50 different rpoB sequence types (RSTs) were identified. RST 1 was assigned to a major RST that included 34.7% (50/144) of the analyzed strains. RST 2 to RST 50 were then assigned to other strains with higher nucleotide sequence similarity to RST 1 in order. RST 1, 11, and 23 were mixed with APEC along with human commensal and pathogenic strains while RST 2, 6, 9, 13-15, 22, 24, 25, 33, 34, 36, and 41 were unique to APEC strains. Only five APEC strains grouped into RST 32 and 47, which contained human pathogenic E. coli (HPEC). Thus, most of the APEC strains had genetic backgrounds different from HPEC strains. However, the minor APEC strains similar to HPEC should be considered potential zoonotic risks. The resolution power of multi-locus sequence typing (MLST) was better than RST testing. Nevertheless, phylogenetic analysis of rpoB was simpler and more economic than MLST.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.4
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• pp.907-915
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• 2007

In this study the effect of water extract of Sophora tonkinensis Gapnep (RST) was investigated on the growth of human lung carcinoma A549 cells. Exposure of A549 cells to RST resulted in the growth inhibition in a dose-dependent manner as measured by MTT assay. The antiproliferative effect by RST treatment in A549 cells was associated with morphological changes such as membrane shrinking and cell rounding up. RST treatment did not induce the cell cycle arrest and the levels of tumor suppressor p53 as well as cyclin-dependent kinase inhibitor p21(WAF1/CIP1). It was found that RST treatment decreased the levels of cyclooxygenase (COX) -2 mRNA and protein expression without significant changes in the expression of COX-1 and inducible nitric oxide synthase (iNOS), which was correlated with a decrease in prostaglandin E2 (PGE2) synthesis. RST treatment also slightly inhibited the levels of human telomerase reverse transcriptase (hTERT) mRNA and protein expression, and the activity of telomerase. Taken together, these findings suggested that RST-induced inhibition of human lung carcinoma A549 cell growth was aoosciated with the inhibition of COX-2 expression and PGE2 production. These results provided important new insights into the possible molecular mechanisms of the anti-cancer activity of RST.

• Food Engineering Progress
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• v.23 no.3
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• pp.193-199
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• 2019

This study aimed to investigate the impact of protease treatments on the yield of rice starch (RST) from frozen rice flours, and to compare the physicochemical properties of RST by alkaline steeping (control) and enzymatic isolation (E-RST) methods. Although the yield of E-RST, prepared according to conditions designed by the modified 23 complete factorial design, was lower than the control, the opposite trends were observed in its purity. E-RST (RST1, isolated for 8 h at 15℃ with 0.5% protease; RST2, isolated for 24 h at 15℃ with 1.5% protease; RST3, isolated for 24 h at 15℃ with 0.5% protease) with the yields above 50% were selected. Amylose contents did not significantly differ for the control and RST2. Relative to the control, solubilities were higher for all E-RST, but swelling power did not significantly differ for E-RST except for RST1. Although all E-RST revealed higher gelatinization temperatures than the control, the reversed trends were found in the gelatinization enthalpy. The pasting viscosities of all E-RST were lower than those of the control. Consequently, the enzymatic isolation method using protease would be a more time-saving and eco-friendly way of preparing RST than the alkaline steeping method, even though its characteristics are different.

• Journal of the Korean Association of Geographic Information Studies
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• v.20 no.2
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• pp.1-16
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• 2017

This study was conducted to analyze the urban heat island(UHI) intensity of South Korea by using Moderate Resolution Imaging Spectroradiometer(MODIS) satellite imagery. For this purpose, the metropolitan area was spatially divided according to land cover classification into urban and non-urban land. From the analysis of land surface temperature(LST) in South Korea in the summer of 2009 which was calculated from MODIS satellite imagery it was determined that the highest temperature recorded nationwide was $36.0^{\circ}C$, lowest $16.2^{\circ}C$, and that the mean was $24.3^{\circ}C$, with a standard deviation of $2.4^{\circ}C$. In order to analyze UHI by cities and counties, UHI intensity was defined as the difference in average temperature between urban and non-urban land, and was calculated through RST1 and RST2. The RST1 calculation showed scattered distribution in areas of high UHI intensity, whereas the RST2 calculation showed that areas of high UHI intensity were concentrated around major cities. In order to find an effective method for analyzing UHI by cities and counties, analysis was conducted of the correlation between the urbanization ratio, number of tropical heat nights, and number of heat-wave days. Although UHI intensity derived through RST1 showed barely any correlation, that derived through RST2 showed significant correlation. The RST2 method is deemed as a more suitable analytical method for measuring the UHI of urban land in cities and counties across the country. In cities and counties with an urbanization ratio of < 20%, the rate of increase for UHI intensity in proportion to increases in urbanization ratio, was very high; whereas this rate gradually declined when the urbanization ratio was > 20%. With an increase of $1^{\circ}C$ in RST2 UHI intensity, the number of tropical heat nights and heat wave days was predicted to increase by approximately five and 0.5, respectively. These results can be used for reference when predicting the effects of increased urbanization on UHI intensity.

• Journal of Electrical Engineering and Technology
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• v.3 no.3
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• pp.308-313
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• 2008

This article proposes the study and simulation of an RST regulator based on a double fed induction machine. The RST polynomial controller can improve the double fed induction machine performance in terms of overshoot, rapidity, cancellation of disturbance, and capacity to maintain a high level of performance. A control law is synthesized using an RST controller. Simulation results indicate that the proposed regulator has better performance response to speed variation, sensitivity to perturbation, and robustness. The designed control algorithm is tested on a simulation matlab code.

• Electronics and Telecommunications Trends
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• v.26 no.6
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• pp.164-173
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• 2011

혁신적인 아키텍처와 서비스를 검증하기 위해 대규모의 실험 설비를 갖춘 미래인터넷 테스트베드가 요구되고 있으며 이러한 연구의 일환으로, FiRST 프로젝트에서는 엄격한 자원 격리를 지원하는 네트워크 가상화 기술과 사용자가 원하는 네트워크를 쉽게 구성하도록 하는 네트워크 프로그램화 기술을 개발하고 있다. 한편, 미래인터넷 생태계 조성을 통한 국가기술 경쟁력 확보 차원에서 KOREN 기반 미래인터넷 테스트베드 구축 사업을 진행하고 있다. 이에 따라, 본 고에서는 KOREN 연구개발망에서 FiRST 프로젝트의 중간 결과물인 FiRST 플랫폼의 구축 과정을 기술하고자 한다.

• Proceedings of the Korea Electromagnetic Engineering Society Conference
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• 2001.11a
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• pp.332-336
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• 2001

The new RST is recently developed by the product expansion of the scattering functions in the field of acoustics. The new formulation suggests that the scattering coefficients consist of resonance, non-resonance, and their interactional components. In the scattering problems of acoustic waves, the moduli and phase of the resonance coefficient are obtained the appropriate results through the new RST. In our recent works the new RST was successfully applied to the scattering problem of electromagnetic waves for coated conducting cylinder and sphere. In this paper, the new RST is applied to the 2-dimensional scattering problem of electromagnetic waves for a homogeneous dielectric cylinder, and the numerical results are compared with the previous RST.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.13 no.1
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• pp.87-93
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• 2002

The previous RST postulates that the scattering field, within each modal partial wave, comprise of the resonance and the background components. The new RST is recently developed by the product expansion of the scattering functions in the field of acoustics. The new formulation suggests that the scattering coefficients consist of resonance, non-resonance, and their interactional portions. In the scattering problems of acoustic waves, the moduli and phase of the resonance coefficient are obtained correctly by the new RST. In our recent works the new RST was successfully applied to the scattering problem of electromagnetic waves for coated conducting cylinder and sphere. In this paper, the new RST is extended to the 2-dimensional scattering problem of electromagnetic waves for a homogeneous dielectric cylinder, and the numerical results are compared with the previous RST.

• Food Science and Preservation
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• v.8 no.4
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• pp.419-426
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• 2001

This study was carried out to develope a convenient instant spiced Toha-jeot. Toha-jeot was manufactured by five samples; 8%, 10%, 13% 23% sodium chloride and a conventional type soy sauce. The Toha-jeot was refrigerated at 4$\pm$1$\^{C}$ for 3 months and then boiled glutinous rice, red pepper powder, chopped garlic and ginger were added, and the spiced Toha-jeot was fermented at 4$\pm$1$\^{C}$ for 2 months, was freeze-dried at a condition of 40$\^{C}$, vacuum 100∼200 millitor millitorr and then packed in vacuum. It is called freeze-dried instant spiced Toha-jeot (FIST). Changes in the components and quality of refrigerated spiced Toha-jeot (RST) and FIST were investigated for 30day. The moisture content of RST was 53.79∼58.91%. Among the mineral constituents of RST, Na and Ca were dominantly occupying. Water activity of FIST was 0.28-0.39 while that of RST was 0.87-0.92. TBA value of FIST was lower than that of RST. Acidity, VBN (volatile basic nitrogen) and TBA(thiobarbituric acid) of the FIST and RST increased slightly, whereas pH decreased. The major components of fatty acids in FIST and RST were analysed into a feater amount of linoleic acid (Cl8:2), palmitic acid (Cl6:1), oleic acid (Cl8:1), linolenic acid (Cl8:3), EPA (C2O:5) and stearic acid(Cl8:0). In sensory evaluation, the RST had higher scores in color and taste and the FIST in chewiness and flavor. The qualitative characteristics and sensory evaluation of FIST and RST were similar.