• Journal of the Institute of Electronics Engineers of Korea SD
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• v.42 no.7 s.337
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• pp.27-36
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• 2005

This paper presents an area-efficient architecture to implement the high-speed Reed-Solomon(RS) decoder, which is used in a variety of communication systems such as wireless and very high-speed optical communications. We present the new pipelined-recursive Modified Euclidean(PrME) architecture to achieve high-throughput rate and reducing hardware-complexity using folding technique. The proposed pipelined recursive architecture can reduce the hardware complexity about 80$\%$ compared to the conventional systolic-array and fully-parallel architecture. The proposed RS decoder has been designed and implemented with the 0.13um CMOS technology in a supply voltage of 1.2 V. The result show that total number of gate is 393 K and it has a data processing rate of S Gbits/s at clock frequency of 625 MHz. The proposed area-efficient architecture can be readily applied to the next generation FEC devices for high-speed optical communications as well as wireless communications.

• Genomics & Informatics
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• v.9 no.2
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• pp.64-68
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• 2011

Monomelic amyotrophy (MA), also known as Hirayama disease, occurs mainly in young men and manifests as weakness and wasting of the muscles of the distal upper limbs. Here, we sought to identify a genetic basis for MA. Given the predominance of MA in males, we focused on candidate neurological disease genes located on the X chromosome, selecting two X-linked candidate genes, androgen receptor (AR ) and ubiquitin-like modifier activating enzyme 1 (UBA1). Screening for genetic variants using patients' genomic DNA revealed three known genetic variants in the coding region of the AR gene: one nonsynonymous single-nucleotide polymorphism (SNP; rs78686797) encoding Leu57Gln, and two variants of polymorphic trinucleotide repeat segments that encode polyglutamine (CAG repeat; rs5902610) and polyglycine (GGC repeat; rs3138869) tracts. Notably, the Leu57Gln polymorphism was found in two patients with MA from 24 MA patients, whereas no variants were found in 142 healthy male controls. However, the numbers of CAG and GGC repeats in the AR gene were within the normal range. These data suggest that the Leu57Gln polymorphism encoded by the X-linked AR gene may contribute to the development of MA.

• The Korean Journal of Physiology and Pharmacology
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• v.18 no.5
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• pp.359-363
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• 2014

MicroRNAs (miRs) are endogenous ${\approx}22$-nt non-coding RNAs that participate in the regulation of gene expression at post-transcriptional level. MiR-1 is one of the muscle-specific miRs, aberrant expression of miR-1 plays important roles in many physiological and pathological processes. In this review, we focus on the recent studies about miR-1 in cardiac diseases and cancers. The findings indicate that miR-1 may be a novel, important biomarker, and a potential therapeutic target in cardiac diseases and cancers.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 1996.06a
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• pp.55-59
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• 1996

In this paper, we first analyze the influence of interference due to the time variation and delay spread of the mobile channel on an orthogonal frequency division multiplexing (OFDM) system. With the result, we obtain the bit error rate performance of the 16-QAM OFDM system. Second, we investigate the performance of the Reed-Solomon (RS) coded 16-QAM OFDM system when the number of subcarriers varies. In the investigation, we assume that the information transmission rate and the total bandwidth expansion due to coding, guard interval, and the number of subcarriers are fixed. Under this condition, it is observed that there are optimum numbers of subcarriers that minimize the post decoding symbol error probability of RS code for various channel states.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2004.11a
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• pp.103-106
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• 2004

본 논문에서는 PC 기반 지상파 DMB(Terrestrial Digital Multimedia Broadcasting, T-DMB) 수신기를 위한 SW 최적화에 대해 설명한다. 이 수신기는 PC 외부에 지상파 DMB 신호를 안테나로 수신하여 복조하고 채널 복호하는 프론트 엔드(front-end) 수신 모듈을 이용, USB를 통하여 RS(Reed-Solomon) 부호화된 MPEG-2 TS(Transport Stream) 데이터를 읽어 들여 RS 복호, TS 역다중화, 비디오 복호, 오디오 복호 등의 SW 처리 과정을 거쳐 디스플레이 상에 수신 내용을 표시하게 된다. 본 논문에서는 저사양 PC에서도 T-DMB를 수신할 수 있도록 H.264/MPEG-4 AVC(Advanced Video Coding) 복호 과정을 최적화한 결과에 대해 설명한다.

• 정보저장시스템학회:학술대회논문집
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• 2005.10a
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• pp.103-110
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• 2005

We present a powerful error control decoder which can be used in all of the commercial DVD systems. The decoder exploits the error information from the modulation decoder in order to increase the error correcting capability. We can identify that the modulation decoder in DVD system can detect errors more than $60\%$ of total errors when burst errors are occurred. In results, fur a decoded block, error correcting capability of the proposed scheme is improved up to $25\%$ more than that of the original error control decoder. In addition, the more the burst error length is increased, the better the decoder performance. Also, a pipeline-balanced RSPC decoder with a low hardware complexity is designed to maximize the throughput. The maximum throughput of the RSPC decoder is 740Mbps@100MHz and the number of gate counts is 20.3K for RS (182, 172, 11) decoder and 30.7K for RS (208, 192, 17) decoder, respectively

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.15 no.5
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• pp.1944-1956
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• 2021

This paper considers a cellular two-way relay network with one base station (BS), one relay station (RS), and two users. The two users are far from the BS and no direct links exist, and the two users exchange messages with the BS via the RS. A non-orthogonal multiple access (NOMA) and network coding (NC)-based decode-and-forward (DF) two-way relaying (TWR) scheme TWR-NOMA-NC is proposed, which is able to reduce the number of channel-uses to three from four in conventional time-division multiple access (TDMA) based TWR approaches. The achievable sum-rate performance of the proposed approach is analyzed, and a closed-form expression for the sum-rate upper bound is derived. Numerical results show that the analytical sum-rate upper bound is tight, and the proposed TWR-NOMA-NC scheme significantly outperforms the TDMA-based TWR and NOMA-based one-way relaying counterparts.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.45 no.2
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• pp.101-111
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• 2008

This paper introduces a high-speed Reed-Solomon(RS) decoder, which reduces the hardware complexity, and presents an RS decoder based FEC architecture which is used for 40Gb/s optical communication systems. We introduce new pipelined degree computationless modified Euclidean(pDCME) algorithm architecture, which has high throughput and low hardware complexity. The proposed 16 channel RS FEC architecture has two 8 channel RS FEC architectures, which has 8 syndrome computation block and shared single KES block. It can reduce the hardware complexity about 30% compared to the conventional 16 channel 3-parallel FEC architecture, which is 4 syndrome computation block and shared single KES block. The proposed RS FEC architecture has been designed and implemented with the $0.18-{\mu}m$ CMOS technology in a supply voltage of 1.8 V. The result show that total number of gate is 250K and it has a data processing rate of 5.1Gb/s at a clock frequency of 400MHz. The proposed area-efficient architecture can be readily applied to the next generation FEC devices for high-speed optical communications as well as wireless communications.

• Korean Journal of Microbiology
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• v.54 no.1
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• pp.69-70
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• 2018

Erwinia pyrifoliae is a Gram-negative bacterium causing black shoot blight in apple and Asian pear trees. E. pyrifoliae strain EpK1/15 was isolated in 2014 from an apple twig from the Pocheon, Gyeonggi-do, South Korea. In this study, we report the draft genome sequence of E. pyrifoliae EpK1/15 using PacBio RS II platform. The draft genome is comprised of a circular chromosome with 4,027,225 bp and 53.4% G + C content and a plasmid with 48,456 bp and 50.3% G + C content. The draft genome includes 3,798 protein-coding genes, 22 rRNA genes, 77 tRNA genes, 13 non-coding RNA genes, and 231 pseudo genes.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.1047-1055
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• 2014

Background: MicroRNAs (miRNAs) are an abundant class of endogenous small non-coding RNAs of 20-25 nucleotides in length that function as negative gene regulators. MiRNAs play roles in most biological processes, as well as diverse human diseases including cancer. Recently, many studies investigated the association between SNPs in miR-146a rs2910164, miR-196a2 rs11614913, miR-149 rs229283, miR-499 rs3746444 and colorectal cancer (CRC), which results have been inconclusive. Methodology/Principal Findings: PubMed, EMBASE, CNKI databases were searched with the last search updated on November 5, 2013. For miR-196a2 rs11614913, a significantly decreased risk of CRC development was observed under three genetic models (dominant model: OR = 0.848, 95%CI: 0.735-0.979, P = 0.025; recessive model: OR = 0.838, 95%CI: 0.721-0.974, P = 0.021; homozygous model: OR = 0.754, 95%CI: 0.627-0.907, P = 0.003). In the subgroup analyses, miR-$196a2^*T$ variant was associated with a significantly decreased susceptibility of CRC (allele model: OR = 0.839, 95%CI: 0.749-0.940, P = 0.000; dominant model: OR = 0.770, 95%CI: 0.653-0.980, P = 0.002; recessive model: OR = 0.802, 95%CI: 0.685-0.939, P = 0.006; homozygous model: OR = 0.695, 95%CI: 0.570-0.847, P = 0.000). As for miR-149 rs2292832, the two genetic models (recessive model: OR = 1.199, 95% CI 1.028-1.398, P = 0.021; heterozygous model: OR = 1.226, 95% CI 1.039-1.447, P = 0.013) demonstrated increased susceptibility to CRC. On subgroup analysis, significantly increased susceptibility of CRC was found in the genetic models (recessive model: OR = 1.180, 95% CI 1.008-1.382, P = 0.040; heterozygous model: OR = 1.202, 95% CI 1.013-1.425, P = 0.013) in the Asian group. Conclusions: These findings supported that the miR-196a2 rs11614913 and miR-149 rs2292832 polymorphisms may contribute to susceptibility to CRC.