• Title/Summary/Keyword: RS:X

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Updated Trans-Ethnic Meta-Analysis of Associations between Inflammation-Related Genes and Intracranial Aneurysm

  • Eun Pyo Hong;Sung Min Cho;Jong Kook Rhim;Jeong Jin Park;Jun Hyong Ahn;Dong Hyuk Youn;Jong-Tae Kim;Chan Hum Park;Younghyurk Lee;Jin Pyeong Jeon;the First Korean Stroke Genetics Association Research (The FirstKSGAR) Study
    • Journal of Korean Neurosurgical Society
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    • v.66 no.5
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    • pp.525-535
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    • 2023
  • Objective : We performed an expanded multi-ethnic meta-analysis to identify associations between inflammation-related loci with intracranial aneurysm (IA) susceptibility. This meta-analysis possesses increased statistical power as it is based on the most data ever evaluated. Methods : We searched and reviewed relevant literature through electronic search engines up to August 2022. Overall estimates were calculated under the fixed- or random-effect models using pooled odds ratio (OR) and 95% confidence intervals (CIs). Subgroup analyses were performed according to ethnicity. Results : Our meta-analysis enrolled 15 studies and involved 3070 patients and 5528 controls including European, Asian, Hispanic, and mixed ethnic populations. Of 17 inflammation-related variants, the rs1800796 locus (interleukin [IL]-6) showed the most significant genome-wide association with IA in East-Asian populations, including 1276 IA patients and 1322 controls (OR, 0.65; 95% CI, 0.56-0.75; p=3.24#x00D7;10-9) under a fixed-effect model. However, this association was not observed in the European population (OR, 1.09; 95% CI, 0.80-1.47; p=0.5929). Three other variants, rs16944 (IL-1β), rs2195940 (IL-12B), and rs1800629 (tumor necrosis factor-α) showed a statistically nominal association with IA in both the overall, as well as East-Asian populations (0.01<p<0.05). Conclusion : Our updated meta-analysis with increased statistical power highlights that rs1800796 which maps on the IL-6 gene is associated with IA, and in particular confers a protective effect against occurrence of IA in the East-Asian population.

Improved Decoding Algorithm on Reed-Solomon Codes using Division Method (제산방법에 의한 Reed-Solomon 부호의 개선된 복호알고리듬)

  • 정제홍;박진수
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.30A no.11
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    • pp.21-28
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    • 1993
  • Decoding algorithm of noncyclic Reed-Solomon codes consists of four steps which are to compute syndromes, to find error-location polynomial, to decide error-location, and to solve error-values. There is a decoding method by which the computation of both error-location polynomial and error-evaluator polynimial can be avoided in conventional decoding methods using Euclid algorithm. The disadvantage of this method is that the same amount of computation is needed that is equivalent to solve the avoided polynomial. This paper considers the division method on polynomial on GF(2$^{m}$) systematically. And proposes a novel method to find error correcting polynomial by simple mathematical expression without the same amount of computation to find the two avoided polynomial. Especially. proposes the method which the amount of computation to find F (x) from the division M(x) by x, (x-1),....(x--${\alpha}^{n-2}$) respectively can be avoided. By applying the simple expression to decoding procedure on RS codes, propses a new decoding algorithm, and to show the validity of presented method, computer simulation is performed.

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다목적 실용위성 3호 RFC 시험 결과의 이론적 검증

  • Jang, Gyeong-Deok;Kim, Tae-Yun;Jang, Jae-Ung;Mun, Gwi-Won
    • The Bulletin of The Korean Astronomical Society
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    • v.37 no.2
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    • pp.196.1-196.1
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    • 2012
  • 인공위성은 지상에서부터 발사 및 궤도 운용까지 다양한 전자파 환경에 노출되며 이러한 환경에서의 위성 운용을 검증하기 위하여, 다양한 전자파 환경을 모사하는 전자파 환경시험을 수행하게 된다. 특히, 궤도내에서 위성의 운용시 지상국과의 교신을 위하여 X 밴드 안테나와 S 밴드 안테나에서 지상국으로 강한 전자기파를 방사하게 되는데, 이 방사에너지가 위성에 영향을 주는지 검증하는 시험을 지상에서 수행한다. 이런 시험을 RFC (RF Auto-Compatibility) 시험이라고 부른다. RFC 시험은 위성으로부터 방사되는 전자기파가 외부에 새어나가지 않도록 전자파 챔버내에서 시험하며, 강한 전자기파를 흡수할 수 있는 고전력 전파 흡수체가 설치된 전자파 챔버가 필요하다. RFC 시험시 X 밴드 안테나와 S 밴드 안테나를 최대 전력으로 방사시키고, 이때 위성 주변에 전자파 센서를 부착하여 전계강도를 측정함으로써 위성으로 입사되는 전자기파의 세기가 적정 레벨 이하인지를 검증하고, 동시에 위성의 운용상태를 확인하여 위성에 영향이 없음을 검증한다. 본 논문에서는 다목적 실용위성 3호의 RFC 시험시 측정된 전계강도를 이론적으로 검증하고, RS 시험시 인가하는 레벨과의 상관관계를 설명한다. RS 시험 레벨의 선정은 위성 안테나의 방사레벨과 관련이 있으며 RFC 시험결과를 검토함으로써 RFC 시험 결과의 유효성과 RF 레벨 요구사항의 적절성을 검증한다.

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A Design and Implementation of the remote control system of vehicle using the G-sensor (G센서를 이용한 차량원격제어시스템 설계 및 구현)

  • Song, Jong-Gun;Kwon, Doo-Wy;Do, Kyeong-Hoon;Jang, Won-Tae
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2009.10a
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    • pp.135-138
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    • 2009
  • G-Sensor is being used for controlling motion of smart-phone and robot. G-Sensor can control motion to several direction, because it is composed of X, Y, and Z axis and also can be used on many mobile-phone by using Wi-Fi communication and RS-232C communication on the Bluetooth module. In this research, we suggest the application that realize and develop visual-vehicle-remote-control-system by using mobile-phone with G-Sensor so that drivers can more easily remote control and manage their vehicle with mobile-phone in real-time visual.

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Morphological study of pulmonary arterioles in patients with ventricular septal defect associated with pulmonary hypertension (폐동맥고혈압을 동반한 심실중격결손증 환자의 폐세동맥의 형태학적 고찰)

  • 조범구
    • Journal of Chest Surgery
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    • v.17 no.3
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    • pp.339-345
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    • 1984
  • Thirty four patients with a ventricular septal defect, aged 2 months to 24 years [median 2.33 years], had lung biopsies during open heart procedures to assess the degree of pulmonary vascular disease. The patients were divided into two groups according to their age; group 1 - under 2 years of age [15 patients], and group 2- over 2 years of age [19 patients]. The, pathologic change of the pulmonary arterioles was correlated with pre-operative hemodynamic data in 34 patients. There was no significant correlation between the severity of pulmonary vascular disease according to Heath-Edwards classification and the patients age [X2=1.8381, P=0.1751 ]. There was a significant correlation between degree of medial wall thickness and arteriolar diameter and the level of preoperative peak pulmonary artery pressure and peak systemic artery pressure [Pp/Ps]. Also, there was a good correlation between the preoperative pulmonary vascular resistance and systemic vascular resistance [Rp/Rs]. There was no significant correlation between wall thickness and Pp/Ps, and Rp/Rs below the age of 2 years. We conclude that, in patients over 2 years of age, there was a significant correlation between the medial wall thickness of the pulmonary arteriole and elevation of Pp/Ps and Rp/Rs. This is not true in patients under 2 years of age.

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Effect of heat treatment of digestion-resistant fraction from soybean on retarding of bile acid transport in vitro

  • Han, Sung-Hee;Lee, Seog-Won;Rhee, Chul
    • Nutrition Research and Practice
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    • v.3 no.2
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    • pp.149-155
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    • 2009
  • In this study, we investigated the heat effect of digestion-resistant fraction (RF) from soybean on retarding bile acid transport in vitro. The RFs from soybean retarded bile acid transport. A raw, unheated RF of soybean (RRF-SOY) was significantly more effective than the heated RF of soybean (HRF-SOY). The RS1 which physically trapped in milled grains and inaccessible to digestive enzyme after 18 hrs incubation level of content in RRF-SOY was found to be as high as 24.1% and after heating the RS1 of HRF-SOY was significantly reduced to 16.8%. The X-ray diffraction pattern of RF from soybean was altered after heat treatment. The RFs from soybean were characterized by peak at diffraction angles of $12.0^{\circ}$ and $20.0^{\circ}$ corresponding to RS content. Cellulose contents of RRF-SOY was 5% higher than that of HRF-SOY and pentosan contents of RRF-SOY was 5% higher than that of HRF-SOY, too. Whereas the hemicellulose content of RRF-SOY was 13% lower than HRF-SOY.

Effect of the Cooking Condition on Enzyme-resistant Starch Content and in vitro Starch and Protein Digestibility of Tarakjuk (Milk-rice Porridge) (타락죽의 효소저항전분 함량과 in vitro 전분 및 단백질 분해율에 대한 가열조건의 영향)

  • Lee, Gui-Chu;Lim, Seung-Taik;Yoon, Hyun-Sung
    • Korean Journal of Food Science and Technology
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    • v.36 no.5
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    • pp.765-772
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    • 2004
  • Cooking condition of Tarakjuk (milk-rice porridge) was established based on gelatinization temperature using differential scanning calorimetry (DSC) of roasted Ilpum rice flour, which has highest enzyme-resistant starch (RS) content. Effect of cooking temperature and time on DSC characteristics, crystallity with X ray diffractogram, RS content, in vitro starch digestibility (IVSD), amino acid composition, and in vitro protein digestibility (IVPD) of Tarakjuk were determined. Tarakjuk was cooked at 50, 56.5, 64, and $69^{\circ}C$ for various durations. Rice flour ingredient used was Ilpum, previously roasted at $185^{\circ}C$ for 25 min. Tarakjuk cooked at 50 and $56.5^{\circ}C$ showed two thermal transitions between $63.7-125.2^{\circ}C$ as determined by DSC, corresponding to endotherms of starch gelatinization $(63.7-73.8^{\circ}C)$ and melting of amylose-lipid complex (AM-lipid complex, $97.7-125.2^{\circ}C$), whereas that cooked at 64 and $69^{\circ}C$ showed only AM-lipid complex melting transition between $96.9-127.6^{\circ}C$. As cooking temperature increased, RS content of Tarakjuk decreased, whereas IVSD increased. Total amino acid content was between 11,558-15,601mg/100g, depending on cooking condition used. Compared with conventionally made control, contents of essential amino acids, such as lysine and tryptophane, were higher at 50 and $56.5^{\circ}C$, and IVPD showed higher increase. Results reveal degree of gelatinization in Tarakjuk with high RS content as well as low IVSD and high IVPD, which are important from physiological and nutritional point of view, can be produced by controlling cooking condition.

Preparation of Prolonged Release Clarithromycin Microparticles for Oral Use and Their In Vitro Evaluation

  • Genc, Lutfi;Demirel, Muzeyyen;Yazan, Yasemin
    • Archives of Pharmacal Research
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    • v.29 no.10
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    • pp.921-927
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    • 2006
  • Prolonged release micro particles of clarithromycin (CL) were prepared using Eudragit RL 100 and RS 100 by spray-drying and casting-drying techniques. For the characterization of those microparticles, preparation yield, particle size distribution, X-ray diffraction, thermal behavior, active agent content and in vitro dissolution from the microparticles were performed. HPLC was used for the assay of clarithromycin and the assay method was validated. All the formulations obtained showed prolonged release when compared to pure clarithromycin. Microparticles prepared by spray-drying method had a slower release compared to those of casting drying method. Spray-drying method seems to be a more suitable method to prepare microparticles for prolongation in release.

Effects of Processing Parameters of Twin Screw Extruder and Dry Methods on the Resistant Starch Formation from Normal Maize Starch (압출성형공정과 건조조건이 옥수수전분의 저항전분 수율에 미치는 영향)

  • Shin, Mal-Shick;Mun, Sae-Hun;Bae, Chun-Ho
    • Korean Journal of Human Ecology
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    • v.5 no.1
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    • pp.62-70
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    • 2002
  • The objective of this study was to evaluate the effects of processing parameters of co-rotating twin screw extruder and dry methods on the level of resistant starch (RS) and the properties of extrudate prepared from normal maize starch. The processing parameters were used 90, 110, 130$^{\circ}C$ in temperature, 25.0~30.0% in moisture content, 150, 200, 250 rpm in screw speed and hot and cool air drying and drying after refrigerating in drying methods. The barrel temperature and drying methods had affected the level of resistant starch of extrudate. RS levels of extrudates were ranged from 2.4 to 15.5% by AOAC method. The extrudates, extruded at 110$^{\circ}C$ and then stored at 4$^{\circ}C$, showed the highest level of RS level (15.5%). Water absorption index increased with increasing moisture content and peak temperatures and viscosities of extudates decreased compare to that of raw starch from 94$^{\circ}C$ to 50~65$^{\circ}C$ and from 220 to 46~98 RVU, respectively. Extudates treated in 90$^{\circ}C$ and 110$^{\circ}C$ showed strong peak at $2{\theta}=6.7{\sim}17.0^{\circ}$ by X-ray diffractometry and had ~150$^{\circ}C$ endotherm like as that of RS3 starch by differential scanning calorimetry. In case of 130$^{\circ}C$, extrudates showed strong peak at $2{\theta}=20.0^{\circ}$ and had 106$^{\circ}C$ endotherm.

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