• The Journal of Korean Academy of Prosthodontics
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• v.32 no.2
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• pp.235-248
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• 1994

There were many studies that distribute the partial edentulous states and examine the removable partial denture designs in the planning of removable partial denture treatment. This study was performed in the point of removable partial denture prescription to evaluate partial edentulism and its removable partial denture designs. The data was collected from the dental laboratory of each three dental colleges in Seoul and from two dental laboratories only for removable partial dentures as a prescription form. A total of 1411 cases with prescription form collected from dental laboratories were distributed for this study, then 788 cases were selected for this study. The case selection was done according to the contents of prescription form. The selected cases were divided into maxillary arch and mandibular and classified in terms of types of major connector and direct retainer, unbroken anterior teeth, Kennedy classification, the number of remaining teeth, and distribution of age and sex. The analyzed results were as follows : 1. The Kennedy classification I showed highest frequency both in maxilla and mandible. 2. The arch distribution of removable partial denture was 50.08% for maxilla and 49.92% for mandible. 3. The highest frequency in the distribution of direct retainer was the RPA clasp design. 4. The frequency of unbroken anterior 6 was 73.36% for maxilla and 82.30% for mandible. 5. The design of broad palatal strap and lingual bar revealed the highest prevalence in the major connector construction. 6. The mean number of remaining teeth per arch was 8.25 for maxilla and 8.37 for mandible. 7. The mean age of the patients supplied with removable partial denture was 52.25 years for men, 51.68 years for women, 52.11 years for maxilla, and 51.76 years for mandible and women showed more prevalence.

• Journal of Korean Neurosurgical Society
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• v.44 no.6
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• pp.358-363
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• 2008

Objective : This study was performed to assess the efficacy of GKS in patients with ten or more brain metastases. Methods : From Aug 2002 to Dec 2007, twenty-six patients (13 men and 13 women) with ten or more cerebral metastatic lesions underwent GKS. The mean age was 55 years (32-80). All patients had Karnofsky performance status (KPS) score of 70 or better. According to recursive partitioning analysis (RPA) classification, 3 patients belonged to class I and 23 to class II. The location of primary tumor was lung (21), breast (3) and unknown (2). The mean number of the lesions per patient was 16.6 (10-37). The mean cumulated volume was 10.9 cc (1.0-42.2). The median marginal dose was 15 Gy (9-23). Overall survival and the prognostic factors for the survival were retrospectively analyzed by using Kaplan Meier method and univariate analysis. Results : Overall median survival from GKS was 34 weeks (8-199). Local control was possible for 79.5% of the lesions and control of all the lesions was possible in at least 14 patients (53.8%) until 6 months after GKS. New lesions appeared in 7 (26.9%) patients during the same period. At the last follow-up, 18 patients died; 6 (33.3%) from systemic causes, 10 (55.6%) from neurological causes, and 2 (11.1 %) from unknown causes. Synchronous onset in non-small cell lung cancer (p=0.007), high KPS score (${\geq}80$, p=0.029), and controlled primary disease (p=0.020) were favorable prognostic factors in univariate analysis. Conclusion : In carefully selected patients, GKS may be a treatment option for ten or more brain metastases.

• Journal of Korean Neurosurgical Society
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• v.59 no.4
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• pp.392-399
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• 2016

Objective : Brain metastases in gynecologic cancer (ovarian, endometrial, and cervical cancer) patients are rare, and the efficacy of Gamma Knife Radiosurgery (GKRS) to treat these had not been evaluated. We assessed the efficacy of GKRS and prognostic factors for tumor control and survival in brain metastasis from gynecologic cancers. Methods : This retrospective study was approved by the institutional review board. From May 1995 to October 2012, 26 women (mean age 51.3 years, range 27-70 years) with metastatic brain tumors from gynecologic cancer were treated with GKRS. We reviewed their outcomes, radiological responses, and clinical status. Results : In total 24 patients (59 lesions) were available for follow-up imaging. The median follow-up time was 9 months. The mean treated tumor volume at the time of GKRS was $8185mm^3$ (range $10-19500mm^3$), and the median dose delivered to the tumor margin was 25 Gy (range, 10-30 Gy). A local tumor control rate was 89.8% (53 of 59 tumors). The median overall survival was 9.5 months after GKRS (range, 1-102 months). Age-associated multivariate analysis indicated that the Karnofsky performance status (KPS), the recursive partitioning analysis (RPA) classification, and the number of treated lesions were significant prognostic factors for overall survival (HR=0.162, p=0.008, HR=0.107, p=0.038, and HR=2.897, p=0.045, respectively). Conclusion : GKRS is safe and effective for the management of brain metastasis from gynecologic cancers. The clinical status of the patient is important in determining the overall survival time.