• Title/Summary/Keyword: RISK FACTORS

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Pathologic Risk Factors and Oncologic Outcomes in Early-stage Cervical Cancer Patients Treated by Radical Hysterectomy and Pelvic Lymphadenectomy at a Thai University Hospital: A 7 year Retrospective Review

  • Ruengkhachorn, Irene;Therasakvichya, Suwanit;Warnnissorn, Malee;Leelaphatanadit, Chairat;Sangkarat, Suthi;Srisombat, Jutatip
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.5951-5956
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    • 2015
  • Background: To evaluate the rate of pathologic high-risk factors, intermediate-risk factors, and treatment outcomes in early-stage cervical cancer patients undergoing radical hysterectomy and pelvic lymphadenectomy (RHPL). Materials and Methods: Medical records of stage IA-IIA1 cervical cancer patients who underwent RHPL during the 2006 to 2012 time period and patient follow-up data until December 2013 were reviewed. Results: Of 331 patients, 52 women (15.7%) had pathologic high-risk factors and 59 women (17.8%) had intermediate-risk factors without high-risk factors. All studied patients had an initial complete response. At median follow-up time of 40.9 months (range 1-103.3 months) and mean follow-up time of$ 43.3{\pm}25.3$ months, 37 women had disease recurrence and 4 women had died of disease. The most common site of recurrence was the pelvis (64.8%). Five-year and 10-year disease free survival rates were 96.1% and 91.5%, respectively. Five-year and 10-year overall survival rates were 100% and 99.4%, respectively. Independent factors related to recurrence were pelvic node metastasis (odds ratio [OR], 2.670; 95%CI, 1.001-7.119), and >1/3 cervical stromal invasion (OR, 3.763; 95%CI, 1.483-9.549). Conclusions: The rates of pathologic high-risk and intermediate-risk factors should be considered and disclosed when counseling patients regarding primary treatment by RHPL. Oncologic outcomes of primary surgical treatment for early-stage cervical carcinoma were found to be excellent.

Characteristics and Risk Factors for Falls in Tertiary Hospital Inpatients (일개 종합병원 입원환자의 낙상관련 특성 및 낙상발생 예측요인)

  • Choi, Eun-Ju;Lee, Young-Shin;Yang, Eun-Jung;Kim, Ji-Hui;Kim, Yeon-Hee;Park, Hyeoun-Ae
    • Journal of Korean Academy of Nursing
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    • v.47 no.3
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    • pp.420-430
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    • 2017
  • Purpose: The aim of this study was to explore characteristics of and risk factors for accidental inpatient falls. Methods: Participants were classified as fallers or non-fallers based on the fall history of inpatients in a tertiary hospital in Seoul between June 2014 and May 2015. Data on falls were obtained from the fall report forms and data on risk factors were obtained from the electronic nursing records. Characteristics of fallers and non-fallers were analyzed using descriptive statistics. Risk factors for falls were identified using univariate analyses and logistic regression analysis. Results: Average length of stay prior to the fall was 21.52 days and average age of fallers was 61.37 years. Most falls occurred during the night shifts and in the bedroom and were due to sudden leg weakness during ambulation. It was found that gender, BMI, physical problems such elimination, gait, vision and hearing and medications such as sleeping pills, antiarrhythmics, vasodilators, and muscle relaxant were statistically significant factors affecting falls. Conclusion: The findings show that there are significant risk factors such as BMI and history of surgery which are not part of fall assessment tools. There are also items on fall assessment tools which are not found to be significant such as mental status, emotional unstability, dizziness, and impairment of urination. Therefore, these various risk factors should be examined in the fall risk assessments and these risk factors should be considered in the development of fall assessment tools.

Lung Cancer Risk Prediction Method Based on Feature Selection and Artificial Neural Network

  • Xie, Nan-Nan;Hu, Liang;Li, Tai-Hui
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10539-10542
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    • 2015
  • A method to predict the risk of lung cancer is proposed, based on two feature selection algorithms: Fisher and ReliefF, and BP Neural Networks. An appropriate quantity of risk factors was chosen for lung cancer risk prediction. The process featured two steps, firstly choosing the risk factors by combining two feature selection algorithms, then providing the predictive value by neural network. Based on the method framework, an algorithm LCRP (lung cancer risk prediction) is presented, to reduce the amount of risk factors collected in practical applications. The proposed method is suitable for health monitoring and self-testing. Experiments showed it can actually provide satisfactory accuracy under low dimensions of risk factors.

Health Behavior Factors Related Type 2 Diabetes by Obesity for Health Promotion in Adolescents (청소년 건강증진교육을 위한 비만여부에 따른 당뇨병 관련 건강행태)

  • Paek, Kyung-Won;Chun, Ki-Hong
    • Journal of the Korean Society of School Health
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    • v.21 no.2
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    • pp.61-73
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    • 2008
  • Purpose: Several health behavior factors affect the incidence of type 2 diabetes. Especially, obesity, which causes insulin resistance, is the most important determinant of diabetes. Therefore, we expect the risk factors associated with insulin resistance and type 2 diabetes are affected by obesity and, additionally, the related factors with diabetes caused by obesity can be controlled. Methods: This study used data collected from the 2001 Korea National Health and Nutrition Examination Survey (KNHANES). A stratified multistage probability sampling method was applied and the final sample included 5,500 subjects over 30 years old who had completed necessary health examinations and health behaviors survey. Results: The risk factors associated with type 2 diabetes are affected by obesity. According to logistic regression model stratified by body mass index (BMI) and sex, abdominal obesity and age were the significant risk factors of diabetes regardless of sex and BMI. However, drinking, smoking, total energy consumption, and protein consumption were risk factors for women with normal BMI, while carbohydrate consumption was a risk factor for man with normal BMI. Sleeping hours affected diabetes for women with obesity and fiber consumption was a risk factor for both women and men with obesity. In addition, statistically the family history of diabetes was a significant risk factor only in the group with normal weight, not in the group with obesity. Conclusion: The study results will provide information for implementing a regional initiative of type 2 diabetes prevention by BMI.

Relation of serum total antioxidant status with metabolic risk factors in Korean adults

  • Kwak, Ho-Kyung;Yoon, Sun
    • Nutrition Research and Practice
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    • v.1 no.4
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    • pp.335-340
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    • 2007
  • The purpose of the present study was to examine the relation of total antioxidant status (TAS) to metabolic risk factors in Korean adults. Anthropometric measures, blood pressure, serum lipids and fasting glucose were determined in 406 men and women. TAS was measured by using commercially available Randox kit. Serum TAS was significantly positively correlated with body weight (p=0.004), body mass index (BMI) (p=0.033), waist circumference (p=0.017), total cholesterol (p=0.038) and triglyceride (TG) (p<0.001). The mean TAS of hypertriglyceridemic subjects (TG ${\geq}$150 mg/dl) was significantly higher than that of subjects whose TG was lower than 150 mg/dl (p=0.001). When central obesity, TG, high density lipoprotein cholesterol, fasting glucose and blood pressure were considered as metabolic risk factors, TAS was shown to be elevated with increased number of metabolic risk factors (p=0.004). The positive association between TAS and a number of metabolic risk factors suggests that increased TAS may not always indicate one's healthier condition. In order to help understand TAS as a marker of total antioxidant capacity in humans with various metabolic conditions, it is needed to clarify the factors affecting TAS in relation to changes in metabolic risk factors.

A Study on The Risk Level of Work Types in Urban Railway Construction (도시철도 건설공사의 공종별 위험도에 관한 연구)

  • Lee, Jong-Bin;Han, In-Kuk;Chang, Seong Rok
    • Journal of the Korean Society of Safety
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    • v.31 no.2
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    • pp.98-103
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    • 2016
  • The goals of this study were to investigate some significant factors to judge level of safety at urban railway construction field and to analyze degree of risk by work classification. Currently, there are lots of construction fields for the urban railway for national transportation, and our government also planned constructing more urban railway in near future. However, most of the researches on safety neglected the degree of risk factors on the urban railway construction field. Safety managers participated in the brainstorming session for deriving decision criteria of the degree of risk (i.e., significant factors). Then, they were asked to answer a structured questionnaire which was developed for deriving most important factors. Finally, the analytic hierarchy process (AHP) was used to analyze level of risk by work classification. The following results were obtained. First, total twelve factors judging degree of risk were found in the brainstorming session. Second, the questionnaire showed four significant factors, including adjacency of obstacle, intensity of work, unsafe condition and work space. Third, the results of AHP showed civil work is the most dangerous work among 6 work types. The results could be used to give the safety management priority on accident prevention efforts among several hazards and to reduce degree of risk in construction field of the urban railway.

Risk Factors for Thyroid Cancer in Females Using a Logit Model in Lahore, Pakistan

  • Asif, Faiza;Ahmad, Muhammad Riaz;Majid, Arshia
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.15
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    • pp.6243-6247
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    • 2015
  • Background: Thyroid cancer (TC) is a more common endocrine malignancy in females and is a major cause of death in developing countries. Therefore the aim of this study was to explore possible risk factors of thyroid cancer in females of Pakistan. Materials and Methods: This study covered 232 females, including 127 (54.7%) cases and 105 (45.2%) controls, from the INMOL Hospital and Sheikh Zayed Hospital, Lahore. Different risk factors were explored by the descriptive and inferentially statistics. Odds ratios and 95% confidence intervals for different risk factors were computed using logistic regression. Results: The results showed six risk factors, marital status, family history of thyroid cancer, iodine in the diet, oxidative stress, fast food and fried food, to demonstrate positive significant links to thyroid cancer (odds ratios and 95% confidence intervals of :2.152, 1.104-4.198; 2.630, 1.416-4.887; 2.391, 1.282-4.458; 4.115, 2.185-7.750; 3.656, 1.851-7.223; 2.357, 1.268-4.382; and 2.360, 1.199-4.643, respectively). Conclusions: The Oxidative stress, marital status, family history of cancer, fast food, use of iodine diet and fried food are the risk factors of thyroid cancer in females.

Perception of the Patient Safety Risk Factors and Safety Management by Nurses in Emergency Service, Hospitals (응급실 간호사의 환자안전 위험요인에 대한 위험성 인식과 안전 간호활동)

  • Yun, Jung MI;Park, Hyoung Sook
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.21 no.4
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    • pp.380-391
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    • 2014
  • Purpose: This was a descriptive research study to examine the patient safety risk factors and the level of safety management of nurses in emergency service, hospitals and to analyze the relationship between the two factors. Method: Data for analysis were collected from 232 nurses in emergency service, hospitals in Busan and Gyeongnam from July 30 to September 7, 2013. Data were analyzed using descriptive statistics, t-test, one-way ANOVA, and Pearson correlation coefficients. Results: Therapeutic agents showed the highest risk level. The prevention of transfusion errors showed the highest performance. As the nurses were working in regional emergency medical centers and received education more than 7 sessions on patient safety, they readily recognized the riskiness of the safety risk factors. In addition, as the nurses were older than 40, married, having more education about safety and understood the incident report registration system well, they performed safety management better. There were significant correlations between perception of the patient safety risk factors and performance for safety management. Conclusion: Nurses in emergency service, hospitals should try to improve safety management to reduce the risk factors shown to be higher based on the results and ensure the patient safety.

Odds ratio of major risk factors associated with delirium by Bayesian network (베이지안 네트워크를 활용한 정신장애 질병 섬망의 주요 위험인자와 오즈비)

  • Lee, Jea-Young;Choi, Young-Jin
    • Journal of the Korean Data and Information Science Society
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    • v.22 no.2
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    • pp.217-225
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    • 2011
  • It is important to find risk factors associated with mental disorder. Also the hazard ratio that represent the relationship of risk factors with illness is main interest in medicine. Thus we used odds ratio to explore the relationship between mental disorder and risk factors. On this paper, when we applied Bayesian network to delirium of mental disorder, we selected major risk factors and calculated odds ratio. Especially we identified odds ratio of single risk factors and multiple risk factors.

Risk Factors for Surgical Site Infections According to Electronic Medical Records Data (전자의무기록(EMR) 자료를 활용한 수술부위감염 관련요인)

  • Kim, Young Hee;Yom, Young-Hee
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.21 no.2
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    • pp.151-161
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    • 2014
  • Purpose: The purpose of this study was to identify the risk factors that influence surgical site infections after surgery. Methods: This study was a retrospective research utilizing Electronic Medical Records. Data collection targeted 4,510 adult patients who had 8 different kinds of surgery (gastric surgery, colon surgery, laparoscopic cholecystectomy, hip & knee replacement, hysterectomy, cesarean section, cardiac surgery) in 4 medical care departments, at one general hospital between January 2006 and December 2011. Multivariate logistic regression analyses were used to identify the risk factors affecting surgical site infections after surgery. Results: Risk factors for increased surgical site infection following surgery were confirmed to be age (OR=1.59, p<.001), BMI (Body Mass Index)(OR=1.25, p=.034), year of operation (OR=2.45, p<.001), length of operation (OR=3.06, p<.001), ASA (American Society of Anesthesiology) score (OR=1.36, p=.025), classification of antibiotic used (OR=2.77, p<.001), duration of the prophylactic antibiotics use (OR=1.85, p<.001), and interaction between classification of antibiotic used and duration of the prophylactic antibiotics use (OR=1.90, p=.016). Conclusions: Results suggest that risk factors affecting surgical site infections should be monitored before surgery. The results of this study should contribute to establishing effective infection management measures and implementing surveillance systems for patients who have actual risk factors.