• Journal of the Korean Society of Systems Engineering
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• v.19 no.2
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• pp.46-58
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• 2023

Deterministic safety analysis is a crucial part of safety assessment, particularly when it comes to demonstrating the safety of nuclear power plant designs. The traditional approach to deterministic safety analysis models is to model the nuclear core using point kinetics. However, this simplified approach does not fully reflect the real core behavior with proper moderator and fuel reactivity feedbacks during the transient. The use of Multi-Physics approach allows more precise simulation reflecting the inherent three-dimensionality (3D) of the problem by representing the detailed 3D core, with instantaneous updates of feedback mechanisms due to changes of important reactivity parameters like fuel temperature coefficient (FTC) and moderator temperature coefficient (MTC). This paper addresses a CEA ejection accident at hot full power (HFP), in which the underlying strong and un-symmetric feedback between thermal-hydraulics and reactor kinetics exist. For this purpose, a multi-physics analysis tool has been selected with the nodal kinetics code, 3DKIN, implicitly coupled to the thermal-hydraulic code, RELAP5, for real-time communication and data exchange. This coupled approach enables high fidelity three-dimensional simulation and is therefore especially relevant to reactivity initiated accident (RIA) scenarios and power distribution anomalies with strong feedback mechanisms and/or un-symmetrical characteristics as in the CEA ejection accident. The Systems Engineering approach is employed to provide guidance in developing the work in a systematic and efficient fashion.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.3 no.2
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• pp.175-180
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• 2000

Purpose: Leptin is an adipocyte-derived blood-borne satiety factor that acts on its cognate leptin receptor in the hypothalamus, thereby regulating food intake and energy expenditure. We measured the leptin concentrations in serum of normal and obese children with human leptin ELISA kit, unlike previous study with leptin RIA kit and investigated the relationship between leptin concentrations and body mass index, gender, and age. Methods: We measured serum concentrations of leptin in 67 children who were visited to the Department of Pediatrics, Chungnam National University Hospital during the period of 5 months from February, 1999 to June, 1999. Height, weight, obesity index, and body mass index were measured in 67 subjects. Leptin values in serum were measured by sandwich ELISA method. Data analysis was done according to the obesity, body mass index, gender and age. Results: The mean concentration of leptin was $7.69{\pm}8.83\;ng/ml$ in normal children group and $36.34{\pm}18.57\;ng/ml$ in obese group. Serum leptin concentrations were significant correlation with the body mass index (p<0.01). Serum leptin concentration was significant higher in the group of over 10 years of age (p<0.01). Leptin levels showed no significant difference by gender. Conclusion: Serum leptin levels were significantly higher in obesity group than in control one, and they were correlated with body mass index and age. Measurements of leptin value by sandwich ELISA method are very useful and easily applicable to determine obesity.

• Journal of Mechanical Science and Technology
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• v.20 no.4
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• pp.494-504
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• 2006

This research proposes a reliability-based topology optimization (RBTO) using the finite element method. RBTO is a topology optimization based on probabilistic (or reliability) constraints. Young's modulus, thickness, and loading are considered as the uncertain variables and RBTO is applied to static and eigenvalue problems. The RBTO problems are formulated and a sensitivity analysis is performed. In order to compute probability constraints, two methods-RIA and PMA-are used. Several examples show the effectiveness of the proposed method by comparing the classical safety factor method.

• Nuclear Engineering and Technology
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• v.52 no.9
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• pp.1990-1997
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• 2020

To support the safe operation of the Miniature Neutron Source Reactor (MNSR), a thermo-hydraulic transient model using the RELAP5/Mod3.2 code was simulated. The model was verified by comparing the results with the measured and the previously calculated data. The comparisons consisted of comparing the MNSR parameters under normal constant power operation and reactivity insertion transients. Reactivity Insertion Accident (RIA) for three different initial reactivity values of 3.6, 6.0, and 6.53 mk have been simulated. The calculated peaks of the reactor power, fuel, clad and coolant temperatures in hot channel were calculated in this model. The reactor power peaks were: 103 kW at 240 s, 174 kW at 160 s and 195 kW at 140 s, respectively. The fuel temperature reached its maximum value of 116 ℃ at 240 s, 124 ℃ at 160 s and 126 ℃ at 140 s respectively. These calculation results ensured the high inherently safety features of the MNSR under all phases of the RIAs.

• Journal of Environmental Health Sciences
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• v.27 no.4
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• pp.115-122
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• 2001

The purpose of this study was to investigate the metallothionein of acute cadmium poisoning mice as a Cadmium index. Forty male ICR mice were injected with cadmium chloride solution from 1/8LD50 to 1/2LD50 dose. At 24 hours after exposed Cd, I examined Cd and metallothionein (MT) intissues(liver and kidney) and fluids(whole blood and urine) and also measured low molecular proteins, N-acetyl-D-glucosaminidase(NAG) and 2- microglobuline (2-MG) in urine. The concentration of Cd and MT of liver kidney whole blood and urine were increased with dose dependent manner. Urinary Cd and urinary MT and very good significance (p<0.01) and urinary MT had good significance with kidney Cd and NAG but not 2-MG Conclusionally MT in urine was very correlated with kidney Cd and urine Cd, So MT maybe useful as a Cd poisoning index.

• Clinical and Experimental Reproductive Medicine
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• v.6 no.1_2
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• pp.23-28
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• 1979

To determine whether hormone analysis of amniotic fluid could be used for accurate determination of fetal sex, we measured testosterone(T) and follicle-stimulating hormone in 19 amniotic fluid samples. The mean T in amniotic fluid of 8 women earring male fetuses was 310 pg. per milliliter and of 11 women earring female fetuses was 150 pg. per milliliter (P<0.05${\ast}$). The mean amniotic fluid FSH of 1.16 mI.U. per milliliter for 7 women with male fetuses was over trifold lower than that for subjects with female fetuses. The mean amniotic fluid FSH of female fetuses was 3.85 mI.U. per milliliter (P<0.01${\ast}$) Measurement of T & FSH in amniotic fluid may be an adjunct method for fetal sex determination.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.19 no.2
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• pp.224-229
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• 2010

This paper presents a reliability-based topology optimization (RBTO) using bi-directional evolutionary structural optimization (BESO). An actual design involves uncertain conditions such as material property, operational load and dimensional variation. Deterministic topology optimization (DTO) is obtained without considering of uncertainties related to the uncertainty parameters. However, the RBTO can consider the uncertainty variables because it has the probabilistic constraints. In this paper, the reliability index approach (RIA) is adopted to evaluate the probabilistic constraint. RBTO based on BESO starting from various design domains produces a similar optimal topology each other. Numerical examples are presented to compare the DTO with the RBTO.

• Korean Journal of Ecology and Environment
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• v.33 no.4 s.92
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• pp.358-365
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• 2000

To evaluate the influences of stocking and removal of silver carp on plankton communities and physicochemical parameters, fish biomanipulation was conducted in six enclosures constructed on the coast of a hypertrophic lake during the summer of 1997. Of these, three enclosures were established for the fish-stocking experiment; one fishless enclosure used as a control and two enclosures with high and low densities of fish. The other three enclosures for the fish-removal experiment were prepared in an entirely converse process compared to that for fish stocking. The results of randomized intervention analysis (${\alpha}=0.05$) showed significant changes in several physicochemical parameters and plankton communities after fish stocking and removal. Fish stocking decreased water transparency, DO, pH and chi-a (> $40\;{\mu}m$), while increasing the concentration of nitrogen and chi-a (<$2\;{\mu}m$). However, water transparency did not increase by fish removal. Small plankton communities, such as picocyanobacteria, eukaryotic picoplankton and ciliates (<$2\;{\mu}m$) showed significant reciprocal changes after both fish treatments: increase by the presence of fish and decrease by the absence of fish. No count of large sized phytoplankton and zooplankton showed significant change in the presence of fish, while large zooplankton, Diaphanosoma, Cyclopida and nauplii were significantly increased by fish removal. Although the frequent heavy-winds and endless supply of phosphorus from the lake sediment strongly disturbed the fish behavior and enclosure management, the stocking and removal of silver carp showed an obvious reciprocal influences on plankton communities and its physico-chemical parameters in a shallow-hypertrophic lake.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.10
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• pp.981-988
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• 2020

Seeing the existence of MSME needs that have still not been met although this sector is undeniably important in Indonesian economy, changes in community behaviour and the intensity of the use of technology in the community, financial technology (fintech) has a lot of potentials to become a part of the solution of the problem commonly faced by MSMEs. Therefore this research needs to be done to observe the potential of fintech in integrating MSMEs in terms of the application of technology and knowledge from the community related to fintech. By using Technology Acceptance Model, this research tries to understand the determinant factors of the fintech application used by MSME. Based on the research framework and model, path analysis method used in this research. This research uses primary data gathered by the questioner, which was distributed to MSME. From the analysis conducted, we can conclude that the external factors tested in this research could have an effect on the behaviour intention through perceived usefulness in MSME practice of financial technology. Large variation in MSME educational background, busineess age and size would become a challenge in promoting fintech application, therefore this finding suggests that fintech should be promoted by highlighting what benefits can be obtained by using fintech application.

• Journal of Navigation and Port Research
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• v.27 no.1
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• pp.1-8
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• 2003

The purpose of this paper is to suggest the regulatory system to the shipping adn Port division. This paper indicates that the regulatory system of Shipping Port, and Logistics division in Korea in the first step and there need to introduce new regulatory quality management system such as Regulatory Import Analysis(RIA). This paper makes new collection criteria based on OECD(1993) standard, and applies to 314 regulation to collect the need to be deregulated, and 5 regulation thar need to introduce new regulatory system.