• The Journal of Asian Finance, Economics and Business
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• v.7 no.9
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• pp.561-572
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• 2020

Sustainable development - including tourism development - is the general trend of all economies. With the orientation to build and develop the tourism industry into a key economic sector and become a tourist center of the Southeast region, Vietnam, Ba Ria-Vung Tau Province is demanding a proper, rational, development policy, while ensuring the development and exploitation of immediate natural advantages, and ensuring long-term sustainable development. The objective of this study is to examine the factors and their trends in sustainable tourism development in Ba Ria-Vung Tau Province, Vietnam. Methods used include descriptive statistical analysis, exploratory factor analysis and regression analysis. Data was collected from the results of a survey of 550 domestic and foreign tourists visiting Ba Ria-Vung Tau. With the help of SPSS statistical software, 12 groups of factors affecting sustainable development were identified including: economy, society, environment, humanistic tourism resources, natural tourism resources, tourism human resources, tourism products and service, tourism quality, infrastructure, technical facilities, governmental management and group of criteria to evaluate sustainable tourism development. The research results show that there are four groups of factors that significantly affect sustainable tourism development in Ba Ria-Vung Tau. These are groups of factors: Society, Environment, Tourism products and service, and Technical facilities.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.8 no.2
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• pp.95-101
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• 2022

Microfluidic radioimmunoassay (RIA) platform called µ-RIA spends less reagent and shorter reaction time for the analysis compared to the conventional tube-based radioimmunoassay. This study reported the design of µ-RIA chips optimized for the gamma counter which could measure the small samples of radioactive materials automatically. Compared with the previous study, the µ-RIA chips developed in this study were designed to be compatible with conventional RIA test tubes. And, the automatic gamma counter could detect radioactivity from the ¹²⁵I labeled anti-PSA attached to the chips. Effects of the multi-layer microchannels and two-phase flow in the µ-RIA chips were investigated in this study. The measured radioactivity from the ¹²⁵I labeled anti-PSA was linearly proportional to the number of stacked chips, representing that the radioactivity in µ-RIA platform could be amplified by designing the chips with multi-layers. In addition, we designed µ-RIA chip to generate liquid-gas plug flow inside the microfluidic channel. The plug flow can promote binding of the biomolecules onto the microfluidic channel surface with recirculation in the liquid phase. The ratio of liquid slug and air slug length was 1 : 1 when the ¹²⁵I labeled anti-PSA and the air were injected at 1 and 35 µL/min, respectively, exhibiting 1.6 times higher biomolecule attachment compared to the microfluidic chip without the air injection. This experimental result indicated that the biomolecular reaction was improved by generating liquid-gas slugs inside the microfluidic channel. In this study, we presented a novel µ-RIA chips that is compatible with the conventional gamma counter with automated sampler. Therefore, high-throughput radioimmunoassay can be carried out by the automatic measurement of radioactivity with reduced radiowaste generation. We expect the µ-RIA platform can successfully replace conventional tube-based radioimmunoassay in the future.

• Nuclear Engineering and Technology
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• v.53 no.11
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• pp.3741-3758
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• 2021

Outcomes of the FALCON code analysis-related part of the STARS-ENSI Service Project on Evaluation of the new U.S.NRC RIA Fuel Safety Criteria and Application to the Swiss Reactors are presented. Substantial conservatism of the updated safety limits for high-temperature and PCMI cladding failure, as proposed in the NRC Regulatory Guide RG 1.236, is confirmed. Applicability of the updated failure limits to fuel safety analysis in the Swiss PWRs, as applied to standard fuel designs using UO2 fuel pellets and SRA Zry-4 as cladding materials is discussed. Conducting of new integral RIA tests with irradiated samples using doped- and gadolinia fuel pellets to support appropriate fuel safety criteria for RIA events is recommended.

• Korean Journal of Environmental Agriculture
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• v.13 no.3
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• pp.262-270
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• 1994

The established methods in the residue analysis of endosulfan require an extensive sample clean-up prior to quantification by relatively complex equipment. A radioimmunoassay(RIA) provides a simple procedure with theoretically higher sensitivity and specificity necessitating only a minimum of sample clean-up. Endosulfan-specific antibodies were developed in rabbits by using a bovine serum albumin(BSA) conjugate wherein the alcohol form of endosulfan was multiply bound to the protein via succinylation. Produced antibodies showed the high titers to endosulfan-BSA(1 : 32,000). An RIA method was developed in water and carp by using $^{14}C-labeled$ endosulfan as a tracer. The lowest detection amount of endosulfan was 1 ng in the liver, kidneys, gut and water samples, and 3 ng in the whole body sample of carp without any clean-up, corresponding to 0.1 ppb of endosulfan.

• Journal of Technology Innovation
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• v.25 no.3
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• pp.233-263
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• 2017

The purpose of this study is to examine the appropriateness of Regulatory Impact Analysis(RIA) in terms of the technological regulation impact assessment in order to confirm whether the current RIA process reflects the important characteristics of technological regulation. This paper develops a logical framework for analysis of technological regulation and evaluates the appropriateness of the RIA statements submitted by the government departments. From the viewpoint of [technological feasibility of regulation], [synthesis of domestic technological norms], [synthesis of international technological norms], as a result of evaluating the contents of the actual RIA statement on the basis of objective facts, feasibility of alternative analysis, and expert judgment, only 23.4% of the RIA statements were judged "appropriate", and there were no particular differences among the government. As a result of reviewing the appropriateness of RIA statements according to regulatory attributes, the appropriateness of RIA statements on technological regulation with social regulatory and indirect regulatory attributes was rather high. In sum, the level of Korean RIA statements is insufficient to carry out the practical meaning of technological regulation impact assessment. That is, as each government department adopts technological regulation, the understanding of the technological properties of the regulation may not be complete. The RIA statement that does not adequately reflect the technological rationale, hinders the careful review of other regulatory alternatives by exaggerating the feasibility of the technology regulation, at the same time leads to the serious problems that impede the acquisition of competitiveness of companies and the public in the global competition system.

• Journal of Korean Neurosurgical Society
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• v.59 no.5
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• pp.458-465
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• 2016

Objective : The aim of this study is to analyze the differences in the incidence, predicting factors, and clinical course of chronic subdural hematoma (CSDH) following surgical clipping between unruptured (UIA) and ruptured intracranial aneurysm (RIA). Methods : We conducted a retrospective analysis of 752 patients (UIA : 368 and RIA : 384) who underwent surgical clipping during 8 years. The incidence and predicting factors of CSDH development in the UIA and RIA were compared according to medical records and radiological data. Results : The incidence of postoperative CSDH was higher in the UIA (10.9%) than in the RIA (3.1%) (p=0.000). In multivariate analysis, a high Hounsfield (HF) unit (blood clots) for subdural fluid collection (SFC), persistence of SFC ${\geq}5mm$ and male sex in the UIA and A high HF unit for SFC and SFC ${\geq}5mm$ without progression to hydrocephalus in the RIA were identified as the independent predicting factors for CSDH development (p<0.05). Conclusion : There were differences in the incidence and predicting factors for CSDH following surgical clipping between UIA and RIA. Blood clots in the subdural space and persistence of SFC ${\geq}5mm$ were predicting factors in both UIA and RIA. However, progression to hydrocephalus may have in part contributed to low CSDH development in the RIA. We suggest that cleaning of blood clots in the subdural space and efforts to minimize SFC ${\geq}5mm$ at the end of surgery is helpful to prevent CSDH following aneurysmal clipping.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.9 no.2
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• pp.29-36
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• 2009

Due to the progress of Bioinformatics field, We are making use of analyzing tools for effective analyzing enormous data of DNA sequence. But there was inconvenience in existing tools when searching and applying data for analyzing. Our treatise proposes a tool developed by a form based on RIA(Rich Internet Application) that you can solve the problems came from weak points. The analyzing tool for RIA indexing data of DNA sequence shows the results by real time in basis of Web 2.0 which supplemented basis on a form of Web. The web application was developed in Flex2 on Windows workstation.

• Spatial Information Research
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• v.20 no.2
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• pp.35-44
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• 2012

Recently, Web map service is actively accomplished in both private companies and public offices. As a platform, it exists variously from desktop to smartphone. The technology being used has a trend to develop continuously. Also, Web map system provides various open API for people who use geospatial service and data mashup. In this paper, RIA technology which is popularly used recently in web map service w ill be applied to introduce the functions different language map services are mostly using. Based on users' feeling about different web browser's speed, test and analysis have been accomplished. The result is that there are different characteristics according to different functions such as JavaScript, Silverlight, Flex. Actual test has been personally carried out on map service in Seoul GIS portal system. The comprehensive conclusion is that Silverlight has more outstanding function compared with other RIA techniques under the test environment.

• BMB Reports
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• v.30 no.6
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• pp.403-409
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• 1997

Studies were undertaken to develop a competitive radioimmunoassay (RIA) and indirect antigen capture enzyme-linked immunosorbent assay (ELISA) for the determination of 5'-deoxy-5'-methylthioadenosine (MTA), which is formed from decarboxylated S-adenosylmethionine by spermidine and spermine synthase. Specific antiserum against MTA was raised in rabbits by immunization with MTA-BSA which was prepared by coupling BSA to oxidized MTA with periodate. Since MTA is oxidized easily to the sulfoxide, the sulfhydryl reagent, DTT. was added to the immunogen. For RIA, immunocomplexes were separated from free MTA by using ammonium sulfate precipitation. The antiserum showed almost no cross-reactivity with a variety of other nucleotides and riboses. But, the level of cross-reactivity of 5'-isobutylthioadenosine (SIBA) was high. These results showed the importance of hydrophobicity adjacent to the 5'-OH for determining antigenicity. The lower limit of detection by this assay was 100 fmol of MTA per tube. Using this assay. MTA levels were more easily and precisely determined in biological samples when compared with HPLC analysis. The RIA procedure is less time consuming. More than 24 analyses can be carried out in 2 h and required only a very small amount of sample ($20{\mu}l$ serum). In ELISA, biotin conjugated MTA-BSA was used as the labelled MTA. The sensitivity limit of this assay was lower than 100 pmol.

• Nuclear Engineering and Technology
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• v.50 no.2
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• pp.280-291
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• 2018

In the framework of OECD/NEA Working Group on Fuel Safety, a RIA fuel-rod-code Benchmark Phase I was organized in 2010-2013. It consisted of four experiments on highly irradiated fuel rodlets tested under different experimental conditions. This benchmark revealed the need to better understand the basic models incorporated in each code for realistic simulation of the complicated integral RIA tests with high burnup fuel rods. A second phase of the benchmark (Phase II) was thus launched early in 2014, which has been organized in two complementary activities: (1) comparison of the results of different simulations on simplified cases in order to provide additional bases for understanding the differences in modelling of the concerned phenomena; (2) assessment of the uncertainty of the results. The present paper provides a summary and conclusions of the second activity of the Benchmark Phase II, which is based on the input uncertainty propagation methodology. The main conclusion is that uncertainties cannot fully explain the difference between the code predictions. Finally, based on the RIA benchmark Phase-I and Phase-II conclusions, some recommendations are made.