• Title/Summary/Keyword: RI

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Analysis of the Latest Trends of Radioisotope Using in RI-Biomics Fields (RI-Biomics분야 RI의 최신 동향 분석)

  • Jang, Sol-Ah;Yeom, Yu-Sun;Park, Tai-Jin;Hwang, Young Muk;Youn, Dol-Mi
    • Journal of Radiation Industry
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    • v.7 no.2_3
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    • pp.221-224
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    • 2013
  • RI-Biomics is a new compound word of radiation technology and Biomics related to the study of life. RI-Biomics is high radiation fusion technology by combining evaluation of pharmacokinetics in vivo (RI-ADME) of new drugs and medical materials using radioisotope and molecular imaging technology using nuclear medicine equipments. RI-Biomics fields are emerging with the increasing usage of radioisotopes (RI). In this paper, we investigated the latest trends of radioisotope using in RI-Biomics fields. The representative radioisotopes are $^{14}C$, $^3H$ and $^{32}P$ for the optimization and the selection of candidates in the development process of new drugs among the RI-Biomics fields. As shown in the status of accumulated income of radioisotopes, using amounts of radioisotopes are showing a tendency to increase every year. $^{14}C$ is 61.6% increase of accumulated income growth rate and $^3H$ increased by 58.8% and $^{32}P$ increased by 33.9% in 2012 compared to 2007. These isotopes are used in a variety of fields as using of $^{14}C$ for microdosing test, development of [$^3H$]cholesterol absorption inhibitors, study of [$^{131}I$]pyronaridine tetraphosphate for malaria therapy. These are going on in vivo test sucessfully. So, clinical research step is expected to begin soon. Therefore, usages of radioisotopes are necessary and need for the evaluation of pharmacokinetics, optimization and the selection of new drug candidates in the development process of new drugs among the RI-Biomics fields. So, using of radioisotopes is predict to increase continuously except for primarily used $^{14}C$, $^3H$.

Consideration of the Direction for Improving RI-Biomics Information System for Using Big Data in Radiation Field (방사선 빅데이터 활용을 위한 RI-Biomics 기술정보시스템 개선 방향성에 관한 고찰)

  • Lee, Seung Hyun;Kim, Joo Yeon;Lim, Young-Khi;Park, Tai-Jin
    • Journal of Radiation Industry
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    • v.11 no.1
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    • pp.7-11
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    • 2017
  • RI-Biomics is a fusion technology in radiation fields for evaluating in-vivo dynamics such as absorption, distribution, metabolism and excretion (RI-ADME) of new drugs and materials using radioisotopes and quantitative evaluation of their efficacy. RI-Biomics information is being provided by RIBio-Info developed as information system for distributing its information and three requirements for improving RIBio-Info system have been derived through reviewing recent big data trends in this study. Three requirements are defined as resource, technology and manpower, and some reviews for applying big data in RIBio-In system are suggested. Fist, applicable external big data have to be obtained, second, some infrastructures for realizing applying big data to be expanded, and finally, data scientists able to analyze large scale of information to be trained. Therefore, an original technology driven to analyze for atypical and large scale of data can be created and this stated technology can contribute to obtain a basis to create a new value in RI-Biomics field.

A Study in the Data Modeling for Archive System Applying RiC (RiC을 적용한 아카이브 시스템 데이터 모델링 연구)

  • Shin, Mira;Kim, Ikhan
    • Journal of Korean Society of Archives and Records Management
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    • v.19 no.1
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    • pp.23-67
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    • 2019
  • Records in Contexts (RiC) is an international archival description standard developed by integrating and normalizing four archival description standards of the International Council of Archives (ICA). RiC has the advantage of diversifying archival description, exposing the context of records, and ensuring data interoperability between disparate systems. In this study, RiC is set up as a key tool in the design of archive systems, and logical data modeling is performed to implement the database. Because of RiC's conceptual model, RiC-CM can be used as a data reference model, and which makes it possible to develop a data model that meets user requirements. Therefore, this study intends to implement these two data models: relational data model, which is widely used as the database on legacy systems, and graphical data model, which can flexibly extend objects around the relationship between information entities.

The Characteristics of Attached Textiles on the Remains of Shimchun-ri and Moonsan-ri Tombs (수착직물의 분석을 통한 심천리와 문산리고분군 직물의 특성)

  • Park, Yoon-Mee;Jeong, Bok-Nam
    • Fashion & Textile Research Journal
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    • v.9 no.2
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    • pp.243-248
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    • 2007
  • This study is about the fabric attached to the relics excavated from the Shimchun-ri tomb of the 4th century and the Moonsan-ri tombs of the 5th century. We studied 5 pieces of fabric from the Shimchun-ri tomb: one piece was silk and the other four pieces were hemp. We were able to observe 8 pieces from the four tombs in Moonsan-ri, All of them except one ramie were silk. The two kinds of bast fiber found in the tombs of Shimchun-ri and Moonsan-ri were hemp and ramie, and they were found to be plain woven with S-twist thread which thickness is uneven. The density was more fine compared to the hemps found in the Kaya or Shinra tombs of the similar era. All of the silk textiles found in the Shimchun-ri and Moonsan-ri tombs used non-twisted thread, and were plain woven. Also, we found degummed and raw silk from the tombs. The average density of the silk textiles from these tombs are similar to other areas of the same time, and studies show that they used non-twisted thread in plain woven silk found in other tombs. Therefore, we can conclude that they usually used non-twisted thread when producing silk textiles.

RI-RSA system design to increase security between nodes in RFID/USN environments (RFID/USN 환경에서 노드들간의 보안성 증대를 위한 RI-RSA 시스템 설계)

  • Lee, Seon-Keun
    • Journal of the Korea Society of Computer and Information
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    • v.15 no.11
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    • pp.157-162
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    • 2010
  • Due to the IT development, RFID/USN became very familiar means of communication. However, because of increased number, security, and size constraints of nodes, it is insufficient to implement a variety of services. To solve these problems, this paper suggests RI-RSA, which is an appropriate asymmetric cryptographic system for RFID/USN environment. The proposed RI-RSA cryptographic system is easy to implement. To increase the processing speed, RI-RSA was suggested by subdividing the multiplication section into two-dimensional, where bottleneck phenomena occurs, and it was implemented in the hardware chip level. The simulation result verified that it caused 6% of circuit reduction, and for the processing speed, RI-RSA was 30% faster compare to the existing RSA.

In vitro Digestibility and Sensory Properties of different Bap(Cooked Rice) (밥의 종류에 따른 in vitro 분해율 및 관능적 특성)

  • Kim, Yoon-Sun;Lee, Gui-Chu
    • Journal of the Korean Society of Food Culture
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    • v.22 no.6
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    • pp.820-826
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    • 2007
  • Different types of bap(cooked rice) was cooked using barley or/and SoRiTae with rice as the base. Total(TS), rapidly digestible(RDS), slowly digestible(SDS) and resistant(RS) starch fractions were determined. Other physicochemical properties such as moisture, protein, amylose contents, protein digestion in vitro and color values as well as sensory properties of different bap were also investigated. Cooked rice with SoRiTae(RiSo) showed the highest moisture content of 63.9%, whereas other bap showed simillar content ranging from 62.3-63.0%. Crude protein content of RiSo was the highest, while that of cooked rice(Ri) was the lowest(p<0.05). Amylose content of RiBa was the highest, while that of RiSo was the lowest(p<0.05). In in vitro protein digestibility(IVPD), cooked rice with barley and SoRiTae(RiBaSo) was the highest, while Ri was the lowest, showing no significant difference at p<0.05. In starch fractions, as barley or/and SoRiTae were added to rice, a decrease in RDS content and increases in SDS and RS contents were observed. In addition, starch digestion index(SDI), which derived as an indicator of their in vitro starch digestibility and rapidly available glucose(RAG) value, which determined as a predictor of potential glycemic response decreased. A decrease in L value from RiSo and RiBaSo, which comprised of SoRiTae and increases in a and b values in RiSo and RiBa were observed, respectively. All sensory parameters involving color, glossiness, sweet taste, wetness, roughness, hardness and stickiness were shown to be a significant difference except sweet taste among different bap(p<0.05). L value of instrumental characteristic was negatively correlated with color of sensory characteristic and a value was positively correlated. Significant negative correlation was found between RS content and glossiness, however, positive correlation with roughness and hardness, respectively. These results suggested that cooked rice mixed with barley and SoRiTae contain significant RS and SDS contents and may improve diabetes and hyperlipidemia, due to the lowering RDS and RAG, respectively.

Evaluation of Ecological Values of the Southern Coastal Wetlands in South Gyeongsang Province, Korea (경상남도 남해안 연안습지의 생태적 가치평가)

  • Park, Kyung-Hun;Yu, Ju-Han;Song, Bong-Geun
    • Korean Journal of Environment and Ecology
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    • v.24 no.4
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    • pp.395-405
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    • 2010
  • This study was carried out to offer basic data to minimize the indiscreet development and damage of coastal wetlands through an evaluation from an ecological standpoint highlighting the importance of the coastal wetland in South Gyeongsang Province, Korea. The result of the macrobenthos survey for the coastal wetland assessment showed that Dongdal and Hwasan-ri, Yongnam-myeon, and Tongyeong city had the largest species number; Oegan-ri and Naegan-ri, Geoje-myeon, and Geoje city had the largest population and biomass; and Miryong-ri, Samsan-myeon, Goseong-gun had the highest species diversity. In the halophytes survey, Imyeong-ri, Jinjeon-myeon, Masan city and Oegan-ri and Naegan-ri, Geoje-myeon, Geoje city had the large character species and companion species. The evaluation results of the ecological values of the coastal wetlands were categorized into five grades based on the field surveys, and the sedimentary environment factor in the case of Danghang-ri, Hoehwa-myeon, and Goseong-gun; Miryong-ri, Samsan-myeon, Goseong-gun; Guho-ri, Gonyang-myeon, Sacheon city; Sulsang-ri Yangpo-ri, Jingyo-myeon, Hadong-gun; and Seokpyeong-ri, Idong-myeon, Namhae-gun, were appraised at the highest rating of grade II. The halophytes factor in the case of Imyeong-ri, Jinjeon-myeon, Masan city, Dongdal-ri and Hwasan-ri, Yongnam-myeon, Tongyeong city and Oegan-ri and Naegan-ri, Geoje-myeon, Geoje city, were highly evaluated as grade II. The macrobenthos factor in the case of Imyeong-ri, Jinjeon-myeon, Masan city and Oegan-ri and Naegan-ri, Geoje-myeon, Geoje city was highly evaluated as grade II. The final evaluation grade was calculated by the mean values of three evaluation factors, and Imyeong-ri, Jinjeon-myeon, Masan city and Oegan-ri and Naegan-ri, Geoje-myeon, and Geoje city had the highest rating of II. On the other hand, Seokpyeong-ri, Idong-myeon, Namhae-gun had the lowest rating of IV. These locations will require future research to survey and monitor the coastal wetland ecosystems by season, in addition to the construction of the GIS-based wetland information system with a view to manage the coastal wetlands.

The Distribution of Flora and Management Status for the Inner Windbreak Forests at Jangsoo-ri and Pyeongsa-ri in Yeosu City (여수시 장수리, 평사리 방풍림일대의 식물분포와 관리실태)

  • Oh, Hyun-Kyung;Kim, Yong-Shik;Kim, Do-Gyun
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.10 no.1
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    • pp.44-56
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    • 2007
  • The flora was summarized as 195 taxa; 73 families, 138 genera, 168 species, 23 varieties and 4 forms in Jangsoo-ri windbreak forest and 151 taxa; 63 families, 118 genera, 131 species, 18 varieties and 2 forms in Pyeongsa-ri windbreak forest. Based on the list of the rare plants by the Forest Research Institute, 3 taxa and based on the list of Korean endemic plant 4 taxa were recorded in the studied areas; Puccinellia coreensis (Gramineae), Asarum maculatum (Aristolochiaceae), Prunus yedoensis (Rosaceae), Koelreuteria paniculata (Sapindaceae), Adenophora triphylla var. hirsuta (Campanulaceae). The Specific Plant Species which is categorized by the Ministry of Environment, Korea, was summarized as 23 taxa for the 1 degree of 17 taxa, 3 degree of 5 taxa, 5 degree of 1 taxa in Jangsoo-ri windbreak forest and 22 taxa for the 1 degree of 18 taxa, 3 degree of 3 taxa, 5 degree of 1 taxa in Pyeongsa-ri windbreak forest. From the enlisted the flora surveyed, the naturalized plants were 17 taxa in Jangsoo-ri windbreak forest and 19 taxa in Pyeongsa-ri windbreak forests with the Naturalization rate was 8.7 percent and 12.6 percent, respectively. In Jangsoo-ri windbreak forest, there has been occurred many man-made impair and development without legal institution and control. So, it needs in haste institutional conservation measures and systemic database construction about function and necessity of windbreak forest. In Pyeongsa-ri windbreak forest, recently many people visited here. So, if we make eco-tour place connecting nearby coast and windbreak forest, it will contribute resident's economic profit and opportunity, concerns about windbreak forest, and necessity of conservation measures. Recently, the windbreak forests in Jangsoo-ri and Pyeongsa-ri should be bereaved windbreak forest of function by the human activities.

Use of Resin Infiltrant to Prevent Discoloration after Teeth Whitening

  • Min, Ji-Hyun
    • Journal of dental hygiene science
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    • v.22 no.3
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    • pp.156-163
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    • 2022
  • Background: This study attempted to apply resin infiltrant (RI) as a method to maintain the effect of tooth bleaching treatment and compared it with fluoride varnish (FV) or artificial saliva to evaluate the effect. Methods: Sixty healthy lozenge specimens were classified into five groups. Group 1 was the negative control group, and discoloration was induced after artificial saliva treatment of the tooth specimen (G1S+C). Group 2 was a positive control group, in which pigmentation was induced after bleaching treatment and artificial saliva treatment (G2 B+S+C). Coloration was induced in group 3 (experimental group 1) after bleaching treatment and artificial saliva treatment, followed by application of fluorine varnish (G3B+FV+S+C). Coloration was induced in Group 4 (experimental group 2) after applying RI after bleaching treatment and artificial saliva treatment (G4B+RI+S+C). Pigmentation was induced in group 5 (experimental group 3) after bleaching treatment and artificial saliva treatment, followed by acid treatment (etching) and treatment with RI (G5B+E+RI+S+C). Coffee and wine were used to induce discoloration. The lightness value (L*) of the CIE L*a*b* color system was obtained by image analysis. Kruskal-Wallis H analysis was performed for the mean difference in L* values by group. Results: When coloration was induced with coffee, there was no significant difference in L* value between artificial saliva (G2 B+S+C), FV (G3B+FV+S+C), and RI (G4B+RI+S+C, G5B+E+RI+S+C) groups. There was no significant difference in L* values between the artificial saliva (G2 B+S+C), FV (G3B+FV+S+C), and RI (G4B+RI+S+C, G5B+E+RI+S+C) groups, even in the case of wine induced coloration. Conclusion: It was confirmed that artificial saliva or RI treatment had similar effects to the FV previously used to maintain the effect of tooth bleaching treatment.

Development and Application of Training Program for RI-Biomics Manpower through Analysis of Educational Demands (교육수요 분석을 통한 RI-Biomics 전문인력 양성 프로그램 개발 및 적용)

  • Shin, Woo-Ho;Park, Tai-Jin;Yeom, Yu-Sun
    • Journal of The Korean Association For Science Education
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    • v.35 no.1
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    • pp.159-167
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    • 2015
  • RI-Biomics is a promising radiation convergence technology that combines radiation with bio science as new growth power technology. Many developed countries are focusing active support and constant exertion to dominate the RI-Biomics market in advance. In order to achieve global leadership in the RI-Biomics field, we need more highly advanced technologies and professional manpower. In fact, we have less manpower compared to technology we currently hold. In this study, we established a basic infrastructure to train professional manpower in the RI-Biomics field by developing/operating optimum training program through expert interviews and survey. The developed program has four organized sections to understand overall procedure of RI-Biomics. To evaluate our training program, we performed test operations with eight students who have a major related to RI-Biomics for three weeks in KARA (Seoul) and KAERI (Jung-eup). In detail, radioisotope usage and safety management were conducted for one week as basic course, RI-Biomics application technology was conducted for two weeks as professional course. To verify performance results of training program, we conducted to journal research, daily reports, and survey on participants. The results show a high level of satisfaction with training programs and continuous intention of involvement in our program. We also need to develop an intensive course to train high-quality human resources and to operate training program continuously. This training program will be used as basic materials for the development of RI-Biomics curriculum for university. Hence, we will expect that our training program contributes in training a professional manpower and develop RI-Biomics technology.