• 재활복지
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• 제21권1호
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• pp.213-231
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• 2017

우반구 손상(Right Hemisphere Damage, RHD)에 따른 의사소통장애는 좌반구 손상 환자군과는 다른 양상을 보이며, 좌반구 손상 환자 대상의 실어증 평가에서는 그 장애 정도가 잘 감별되지 않기 때문에 이들에 대한 언어 평가와 중재연구가 적극적으로 이루어지지 않고 있다. 본 연구에서는 최근 10년간 국내외 관련 학술지에서 다루어진 RHD 환자에 대한 연구논문을 분석하여 RHD 환자의 의사소통장애 평가와 중재 방향에 대한 동향을 파악하고, 향후 임상과 연구 영역에서의 시사점을 얻고자 하였다. 국내외 논문 총 75편(국내 논문 13편, 국외 논문 62편)을 대상으로 연구유형과 연구영역으로 나누어 분석을 실시하였다. 연구유형 및 연구영역에서 국내외 동일하게 RHD 환자의 인지-의사소통장애 특성을 비교하고, 언어외적 능력을 가장 많이 살펴본 것으로 나타났다. 그러나 평가도구 개발 연구 및 인지-의사소통 외 능력(예: 일상생활능력, 우울)과 같이 다양한 주제에 대한 연구가 빈번히 이루어져 있는 국외 연구와는 달리 국내 연구는 아직까지 제한적인 범위 내에서만 이루어져 있었다. 본 논문을 통해 파악된 RHD 환자군의 국내외 연구 동향을 통해 향후 국내 RHD 환자를 대상으로 한 임상장면과 연구에서 다양하고 심도 높은 연구가 이루어질 것으로 기대한다.

• 충청수학회지
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• 제11권1호
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• pp.13-26
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• 1998

The purpose of this note is to study the relation between Heyting algebra and t-algebra which is the dual concept of BCK-algebra. We define t-algebra with binary operation ${\rhd}$ which is a generalization of the implication in the Heyting algebra, and define a bounded ness and commutativity of it, and then characterize a Heyting algebra and a Boolean algebra as a bounded commutative t-algebra X satisfying $x=(x{\rhd}y){\rhd}x$ for all $x,y{\in}X$.

• 한국콘텐츠학회논문지
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• 제11권4호
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• pp.253-262
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• 2011

외상성 뇌손상 및 우반구 손상 환자의 인지-의사소통 능력은 다른 신경학적 장애군과 다른 양상을 띤다. 따라서, 이들의 진단 시 실어증 평가도구 등을 활용하는 것은 바람직하지 않다. 본 연구에서는 두 장애군의 인지-의사소통 능력을 평가할 수 있는 문항을 개발하기에 앞서, 이와 관련된 국외 문헌 및 평가도구를 살펴보고자 하였다. 연구 결과, 외상성 뇌손상 환자의 평가 시에는 주의력, 기억력, 조직화 능력, 추론력, 기능적 의사소통 능력 등을 포괄적으로 고려하는 것이 유용함을 알 수 있었다. 또한, 우반구 손상 이후에는 주의력 등 여러 인지 영역과 함께 고차원적 언어 능력을 평가할 필요성이 제기되었다. 요컨대, 두 장애군의 인지-의사소통 능력을 평가하기 위해서는 다양한 인지-의사소통 영역 간의 영향을 반드시 고려해야 한다. 아울러, 두 장애군을 실어증 등 다른 신경학적 장애군으로부터 변별하고, 치료 시 영역별 지침서로서 활용할 수 있는 평가도구의 개발이 필요하다.

• Journal of Genetic Medicine
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• 제12권2호
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• pp.100-108
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• 2015

Purpose: Conventional methods for the prenatal detection of fetal RhD status involve invasive procedures such as fetal blood sampling and amniocentesis. The identification of cell-free fetal DNA (cffDNA) in maternal plasma creates the possibility of determining fetal RhD status by analyzing maternal plasma DNA. However, some technical problems still exist, especially the lack of a positive control marker for the presence of fetal DNA. Therefore, we assessed the feasibility and accuracy of fetal RHD genotyping incorporating the RASSF1A epigenetic fetal DNA marker from cffDNA in the maternal plasma of RhD-negative pregnant women in Korea. Materials and Methods: We analyzed maternal plasma from 41 pregnant women identified as RhD-negative by serological testing. Multiplex real-time PCR was performed by amplifying RHD exons 5 and 7 and the SRY gene, with RASSF1A being used as a gender-independent fetal epigenetic marker. The results were compared with those obtained by postnatal serological analysis of cord blood and gender identification. Results: Among the 41 fetuses, 37 were RhD-positive and 4 were RhD-negative according to the serological analysis of cord blood. There was 100% concordance between fetal RHD genotyping and serological cord blood results. Detection of the RASSF1A gene verified the presence of cffDNA, and the fetal SRY status was correctly detected in all 41 cases. Conclusion: Noninvasive fetal RHD genotyping with cffDNA incorporating RASSF1A is a feasible, reliable, and accurate method of determining fetal RhD status. It is an alternative to amniocentesis for the management of RhD-negative women and reduces the need for unnecessary RhIG prophylaxis.

• 농업과학연구
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• 제47권2호
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• pp.305-313
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• 2020

Root hair development has the potential to increase crop yields and at the same time to decrease fertilizer use, which will be required in the next 30 years to meet the demand for crop-derived commodities in a world with decreasing available natural resources. Root hair defective six (RHD6) encoding a basic helix-loop-helix transcription factor, is associated with root hair differentiation, and its roles are root hair initiation and elongation. Grass plants, rice and Brachypodium have been used as model plants to study the gene function of the root hair defective six like (RSL) subfamily which is orthologous to AtRHD6. The RSL subfamily has an identical gene function with AtRHD6 which is involved with root hair differentiation as well. Plants with longer root hairs within a species should have an improved Pi uptake efficiency; therefore, we would expect that a plant with a high Pi uptake could contribute to increasing the plant yield. We achieved increased root hair length by manipulating the RSL subfamily genes. It is expected that in these transgenic plants, the long root hairs would be sufficient to improve the Pi uptake and hence improve biomass and yield component (tiller, spikelet number, and spikelet weight) of the plant. Here, we demonstrate that Brachypodium transgenic plants overexpressing the BdRSL subfamily genes have an improved biomass and grain yield. The result of this study could be applied to important crop plants like rice.

• 음성과학
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• 제12권3호
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• pp.91-102
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• 2005

This study investigated to the effects of a mental image drawing in RHD patients with left neglect. Three subjects participated in this study. All subjects were right handed and native speaker of korean. In task 1, the patients were presented with visual stimulus card directly above the response sheet and were asked to draw the picture. In task 2, they were presented with items auditorily and asked to draw the picture(mental image drawing). In all experimental conditions, there was no response time limit. The results showed that the subjects showed left neglect leaving some space on the left side in task 1. And the picture was drawn the left side from the right in direction. However, the neglect disappeared in task 2. And the picture was drawn the right side from the left in direction. The results of the present study suggested that a mental image drawing technique can be effective in treating individuals who exhibit left neglect. Also, the picture direction showed that the korean normality was same.

• 한국정보통신학회논문지
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• 제12권8호
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• pp.1519-1525
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• 2008

최근에 유럽, 미국, 중국, 일본 등 국가별 환경규제 지침에 의해 납, 수은, 카드뮴, 6가 크룸, 폴리브로미네이티드 비폐닐(PBB), 폴리브로미네이티드 등 6개 유해물질의 사용을 제한하고 있다. 본 논문에서는 한지, 닥나무, 섬유성 펄프, PLOYCABONATE등 이용하여 국내의 유일의 섬유성 재질과 접목, 접착하는 친환경 RHD Tag 및 제작방법을 개발하였다. 개발한 RFID Tag는 각각의 layer 사이를 친환경성 소재를 이용하여 접착하였다. 개발한 RFID Tag는 친환경 소재로 제작함으로써 수명이 다하여 RFID 카드를 소각 폐기 처분할 경우 환경오염 물질을 최소화하였다.

• 천문학회보
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• 제45권1호
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• pp.37.2-37.2
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• 2020

We study the structures and dynamics of flows generated by ultra-relativistic jets on kpc scales through three-dimensional relativistic hydrodynamics (RHD) simulations. We employ a newly developed RHD code, equipped with the WENO-Z reconstruction, the SSPRK time discretization, and an equation of state that closely approximates the single-component perfect gas in relativistic regime. Exploring a set of models with various parameters, we confirm that the well-known Fanaroff-Riley dichotomy is primarily determined by the jet power, whereas the morphology of simulated jets also depends on the secondary parameters such as the momentum injection rate and the ratio of the jet to background pressure. Utilizing high resolution capabilities of the newly developed code, we examine in detail the dynamical properties of complex flows in different parts of jet-produced structures, and present the statistics of nonlinear dynamics such as shock, shear, and turbulence.

• 천문학회보
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• 제46권1호
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• pp.36.3-36.3
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• 2021

We study ultra-relativistic jets on several tens kpc scales through three-dimensional relativistic hydrodynamic (RHD) simulations using a new RHD code based on the weighted essentially non-oscillatory (WENO) scheme. Utilizing the high-resolution and high-accuracy capabilities of the new code, we especially explore the structures and energetics of nonlinear flows, such as shocks, turbulence, velocity shear in different parts of jets. We find that the mildly relativistic shocks which form in the jet backflow are most effective for the shock dissipation of the jet energy, while the turbulent dissipation is largest either in the backflow or in the shocked ICM, depending on the jet parameter. The velocity shear is strongest across the jet flow to the cocoon boundary. Our results should have important implications for the studies of high-energy cosmic-ray production in radio galaxies.

• Annals of Laboratory Medicine
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• 제38권6호
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• pp.585-590
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• 2018

Background: Although testing to detect weak D antigens using the antihuman globulin reagent is not required for D- patients in many countries, it is routinely performed in Korea. However, weak D testing can be omitted in D- patients with a C-E- phenotype as this indicates complete deletion of the RHD gene, except in rare cases. We designed a new algorithm for weak D testing, which consisted of RhCE phenotyping followed by weak D testing in C+ or E+ samples, and compared it with the current algorithm with respect to time and cost-effectiveness. Methods: In this retrospective study, 74,889 test results from January to July 2017 in a tertiary hospital in Korea were analyzed. Agreement between the current and proposed algorithms was evaluated, and total number of tests, time required for testing, and test costs were compared. With both algorithms, RHD genotyping was conducted for samples that were C+ or E+ and negative for weak D testing. Results: The algorithms showed perfect agreement (agreement=100%; ${\kappa}=1.00$). By applying the proposed algorithm, 29.56% (115/389 tests/yr) of tests could be omitted, time required for testing could be reduced by 36% (8,672/24,084 min/yr), and the test cost could be reduced by 16.53% (536.11/3,241.08 USD/yr). Conclusions: Our algorithm omitting weak D testing in D- patients with C-E- phenotype may be a cost-effective testing strategy in Korea.