• Title/Summary/Keyword: RESPONSIVENESS

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Genomic epidemiology and surveillance of zoonotic viruses using targeted next-generation sequencing (표적화 차세대염기서열분석법을 이용한 인수공통 바이러스의 유전체 역학과 예찰)

  • Seonghyeon Lee;Seung-Hwan Baek;Shivani Rajoriya;Sara Puspareni;Won-Keun Kim
    • Korean Journal of Veterinary Service
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    • v.46 no.1
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    • pp.93-106
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    • 2023
  • Emerging and re-emerging zoonotic viruses become critical public health, economic, societal, and cultural burdens. The Coronavirus disease-19 (COVID-19) pandemic reveals needs for effective preparedness and responsiveness against the emergence of variants and the next virus outbreak. The targeted next-generation sequencing (NGS) significantly contributes to the acquisition of viral genome sequences directly from clinical specimens. Using this advanced NGS technology, the genomic epidemiology and surveillance play a critical role in identifying of infectious source and origin, tracking of transmission chains and virus evolution, and characterizing the virulence and developing of vaccines during the outbreak. In this review, we highlight the platforms and preparation of targeted NGS for the viral genomics. We also demonstrate the application of this strategy to take advantage of the responsiveness and prevention of emerging zoonotic viruses. This article provides broad and deep insights into the preparedness and responsiveness for the next zoonotic virus outbreak.

The Influence of C2C E-commerce Logistics Service Quality on Customer Satisfaction and Customer Loyalty in China (중국 C2C 전자상거래 물류서비스 품질이 고객만족도와 고객충성도에 미치는 영향)

  • Yin-Jie Tang;Tae-In Kim
    • Asia-Pacific Journal of Business
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    • v.13 no.4
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    • pp.61-77
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    • 2022
  • Purpose - The purpose of this study was to explore the relationship between C2C logistics service quality(convenience, responsiveness, reliability, information and empathy) customer satisfaction and customer loyalty. Design/methodology/approach - This study collected 252 survey data from consumers who use C2C platform in China. Then using SPSS 24.0 in order to analyze the data. This study used SPSS 24.0 to perform empirical analysis with 252 people who use C2C platform in China. Findings - First, it was confirmed that the quality of logistics service(convenience, responsiveness, reliability, information and empathy) had a positive effect on customer satisfaction. Second, logistics service quality(convenience, responsiveness, reliability, information and empathy) positively affects the customer loyalty. Third, there is also a strong relationship between customer satisfaction and customer loyalty. Research implications or Originality - It is well known that logistics is an important part of e-commerce. Research on the influence of B2B logistics service quality on customer satisfaction and customer loyalty is more currently, but research on C2C is relatively less. Our study contributes the related research area by doing empirical analysis of the relationship between the logistics service quality and customer satisfaction and customer loyalty to provide development suggestions for C2C sellers.

An Empirical Study on the Effect of Trust between Firms in the Supply Chain on Agility and Logistics Performance

  • Soohyo KIM;Changjoon LEE;Byoung Chun HA
    • Journal of Distribution Science
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    • v.22 no.7
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    • pp.95-106
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    • 2024
  • Purpose: This study explores the effect on supply chain agility and logistics performance of building mutual trust between manufacturing companies that have adopted supply chain management. Previous studies have categorized trust into affective and cognitive types, and speed, flexibility, and responsiveness are recognized as subfactors of supply chain agility. Methodology: A survey gathered responses from employees of domestic manufacturing firms with supply chain management implementations. 254 valid responses underwent statistical analysis using structural equation modeling (SPSS 23.0 and AMOS 23.0). Results: Affective trust positively influences speed and responsiveness but not flexibility. Cognitive trust positively affects speed, flexibility, and responsiveness. Supply chain agility positively impacts logistics performance. However, neither affective nor cognitive trust significantly influences logistics performance. Conclusions: The study suggests that cognitive trust based on capabilities is more important than affective trust for flexibility in corporate relationships, a subfactor of supply chain agility. However, trust alone cannot enhance corporate performance. This research is significant as it examines the roles of trust and agility in the context of the COVID-19 pandemic, which has exacerbated the manufacturing business environment.

Clinical Features and Long-Term outcomes of Patients with Late Steroid Resistant/Sensitive Nephrotic Syndrome: A Single Center Study

  • Yeh, Hye Ryun;Lee, JooHoon;Park, Young Seo
    • Childhood Kidney Diseases
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    • v.19 no.2
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    • pp.98-104
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    • 2015
  • Objective: To find out clinical features and long-term outcomes of idiopathic childhood nephrotic syndrome(NS) patients with late steroid resistance(LSR)/late steroid sensitiveness(LSS). Patients and Methods: A retrospective chart review was performed on 480 patients diagnosed with idiopathic childhood NS at Asan Medical Center Children's Hospital from 1990 to 2013. Twenty-four patients whose responsiveness to steroids changed over a minimum 2 year follow-up period (2-17.5 years) were investigated. All patients had undergone a renal biopsy. Results: Among 480 nephrotic children, 428 (89%) were sensitive to the first steroid course. Of those who initially responded, 11 (2.5%) developed resistance to steroid therapy after relapses. LSR mostly developed between 1 month and 1 year after the initial episode. Six patients showed a minimal change and five showed focal segmental glomerulosclerosis (FSGS). Nine (82%) responded to cyclosporine or methylprednisolone pulse therapy. Of these, two had no further relapse, whereas the other seven experienced several relapses that ranged in length from 1.1 to 13.9 years. Three of the nine who initially responded to immunosuppression went on to experience several changes in steroid responsiveness. Two (18%) with resistance to immunosuppressants, including steroids, eventually progressed to end stage renal disease. Among the 52 patients (11%) who were initially steroid resistant, 13 (23%) were converted to steroid sensitive at relapses. Among these, 9 showed minimal change and 4 showed FSGS. Two had no further relapse and the other 11 responded to steroids on subsequent relapses ranging in length from 1.3 to 9.4 years. All these patients have had no further changes in steroid responsiveness with normal renal function. Conclusions: In this study, 2.5% of initial steroid responders and 25% of initial steroid non-responders changed their responsiveness to steroids at subsequent relapses. Eighteen percent of LSR patients developed end stage renal disease. All of the LSS patients showed preserved normal renal function. Responsiveness to immunosuppressants seemed to be the most important factor determining longterm outcomes in LSR/LSS patients.

Effects of Dietary Starch and Sucrose on Tissue Responsiveness and Sensitivity to Insulin in Goats Fed a High-concentrate Diet

  • Fujita, Tadahisa;Kajita, Masahiro;Sano, Hiroaki
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.3
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    • pp.385-392
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    • 2007
  • A glucose clamp technique was used to compare dietary starch (ST), starch plus sucrose (ST+SU) and sucrose (SU) with regard to the effect on tissue responsiveness and sensitivity to insulin in intact adult male goats. The goats were fed diets containing 1.2 times of ME and CP for maintenance requirements twice daily for 21 d. Of the energy intake, 30% was offered with ST, ST+SU or SU for the respective diets, and 70% as alfalfa hay, ground corn and ground soybean meal at the respective weight ratio of 1, 1, and 0.3 for all diets. Tissue responsiveness and sensitivity to insulin were evaluated using a hyperinsulinemic euglycemic clamp technique with four levels of insulin infusion beyond 13 h after feeding. The concentrations of plasma metabolites and insulin were also determined at 3, 6 and 13 h after feeding to evaluate the effects of different carbohydrates on metabolic states in the body. Plasma glucose concentration was higher (p = 0.01) for SU diet than for ST and ST+SU diets. Increasing SU intake decreased (p<0.01) plasma acetate concentration across the time. At 3 h but not 6 and 13 h after feeding, high lactate (p = 0.01), and non-significant high propionate (p = 0.14) and low urea nitrogen (p = 0.19) concentrations were observed in plasma on SU compared with ST and ST+SU diets. Plasma insulin concentration was not different (p = 0.44) between ST and SU fed animals. In the glucose clamp experiment, considering the effects on the maximal glucose infusion rate (tissue responsiveness to insulin, p = 0.54) and the plasma insulin concentration at half-maximal glucose infusion rate (insulin sensitivity, p = 0.54), SU was not different from ST. It is concluded that SU may not be greatly different from ST with regard to the effect on tissue responsiveness and sensitivity to insulin in adult goats when fed twice daily as part of a high-concentrate diet. The possible greater effects of SU on plasma metabolites concentrations at 3 h than at 6 and 13 h after feeding suggest that a lack of persistency of SU effects during the postfeeding period may be associated with the poor response to SU in insulin action.

The Impact of Service Perceptions and Product Perceptions on the Formation of Fashion Internet Shoppers' Satisfaction and Purchasing Behavioral Intentions

  • Lee, Seung-Min;Ku, Yang-Suk
    • Fashion & Textile Research Journal
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    • v.3 no.5
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    • pp.395-402
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    • 2001
  • The purpose of this study was to develop the service and product perceptions' dimensions for fashion retail sites and to identify the service and product perceptions' dimensions influencing consumers' satisfaction and purchasing behavioral intentions for fashion retail sites. A set of self-administered questionnaires were e-mailed to an internet Research Panel consisting of members who had purchased fashion products or visited fashion retail sites. 799 questionnaires were analysed using frequency, percentage, exploratory factor analysis. Cronbach's ${\alpha}$, stepwise regression analysis utilizing SPSS 10.0. The service perception dimensions of fashion retail sites had reliability, convenience, incentive, responsiveness and tangibility. Online fashion product perception dimensions were product variety and product value. Consumer satisfaction was influenced by reliability, product variety, product value, convenience, incentive and responsiveness. Consumer satisfaction had a direct impact on purchasing behavioral intentions of fashion retail sites.

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EFFECTS OF HYPOPHYSECTOMY ON PROGESTERONE PRODUCTION IN THE FOLLICULAR GRANULOSA CELLS OF THE JAPANESE QUAIL

  • Mori, M.;Kimora, K.;Yamamuro, H.
    • Asian-Australasian Journal of Animal Sciences
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    • v.1 no.3
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    • pp.143-147
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    • 1988
  • In order to investigate the mechanism of regulation of progesterone production, quail were hypophysectomized at various times during the ovulation cycle, and granulose cells were isolated from follicles 4 hr after the operation. They were incubated in vitro at $40^{\circ}C$ with or without LH or dibutyryl cyclic AMP, and the amounts of progesterone produced during 3 hr of incubation were measured by radioimmunoassay. Hypophysectomy at 8 hr or 20 hr before the predicted time of ovulation caused a reduced responsiveness of F1 granulosa cells to exogenous LH or dibutyrul cyclic AMP. Although hypophysectomy at 24 hr before ovulation caused a slight reduction of responsiveness of F1 granulosa cells, the reduction of the progesterone production during the incubation without any stimuli was prominent by the sham operation. These results suggest that the presence of pituitary gland influences the ability of the granulose cells to produce progesterone in response to LH or dibutyryl cyclic AMP.

Effects of Service Quality in Internet Shopping Mall on Electronic Commerce Performance (인터넷쇼핑몰의 서비스 품질이 전자상거래 성과에 미치는 영향)

  • Yoo, Il;Na, Kwang-Yoon;Choi, Hyuk-Ra
    • The Journal of Society for e-Business Studies
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    • v.4 no.3
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    • pp.77-94
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    • 1999
  • The Electronic Commerce is expected as one of the most prospective industries in the 21th century, This research performed a survey and analysis is based on the results of the service quality model and previous research of the service quality in MIS. Service quality, one instrument developed by the marketing area, is provided as a possible measure of internet shopping mall, Service quality measures five service dimensions of tangible, reliability, responsiveness, assurance and empathy. The main purposes of this study are to develop an exploratory model based on service quality that can explain the factors of customer's perceived service quality and investigate how these factors are related to consumer satisfaction. The results of this survey are summarized as follows: (1) Reliability and responsiveness of internet shopping mall are evaluated as very important factors, (2) Service quality is an antecedent of consumer satisfaction, (3) Consumer satisfaction has a significant effect on purchase intentions.

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A Comparative Study on Service Quality in the Korean Insurance Industry using SERVPERF (한국 보험산업의 서비스품질 결정요인에 관한 연구)

  • 이정우;유한주
    • Journal of Korean Society for Quality Management
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    • v.31 no.1
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    • pp.42-61
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    • 2003
  • The objective of this study is to analyze the impact of service quality on the customer satisfaction, the re-purchase intention and the word of mouth in the Korean insurance industry. In this study, the methodology for measuring the degree of service quality which has been adopted in the service quality research area was used. Data for this study were gathered from 1332 consumer life insurance and 689 consumer non-life insurance companies using internet survey method. The result of this study is summarized as follows: the determinants of service quality in the Korean life insurance industry are empathy, responsiveness and reliability, and the determinants of service quality in the Korean non-life insurance industry are empathy, and responsiveness, and the re-purchase intention and the word of mouth are affected by the customer satisfaction. As a result of the study, strategic implications will be suggested.

The Relationship between Internal Marketing and Service Quality in Telecommunication Sector (정보통신 분야 종사자의 내부마케팅노력이 서비스품질에 미치는 효과)

  • Ahn, Kwan-Young;Park, Rho-Gook
    • Journal of Korean Society for Quality Management
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    • v.35 no.4
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    • pp.78-88
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    • 2007
  • This paper is to investigate the relationship between international marketing and service quality, and the moderating effect of gender in that relationship. The data to make an empirical analysis were gathered from 269 workers in telecommunication sector. Multiple regression analysis revealed that (1) education was positively related with tangibility, reliability, responsiveness, empathy, assurance, and (2) internal communication was positively related with tangibility, reliability, responsiveness, assurance, and (3) delegation of authority was positively related with assurance. Hierarchical multiple regression analysis revealed that (4) compensation was more positively related with reliability in woman, and (5) employment security was more positively related with assurance in man.