• Title/Summary/Keyword: RESPONSE 2000

Search Result 1,863, Processing Time 0.025 seconds

Application of Mathematical Modeling to Extraplate from High Dose to Low Dose for Risk Assessment of Vinyl Chloride (화학물질의 건강 위해성 평가를 위한 수학 통계적 추계 모델링의 응용)

  • 이영조;이석호;이승진;정진호
    • Journal of Food Hygiene and Safety
    • /
    • v.15 no.3
    • /
    • pp.267-270
    • /
    • 2000
  • This study was designed to predict the risk of a hazard chemical, vinyl chloride, by applying dose-response assessment that are one of the major process in practicing risk assessment. After extrapolating from the high dose exposure of vinyl chloride based upon animal carcinogenic data to the low dose exposed to human using several mathematical models, we calculated the cancer potency factors as well as virtually safe dose and the resulted values were compared. This process will provide the new insight to assess the risk of a chemical accurately imposed to human in the future.

  • PDF

The design of the expanded I-PD Controller with the Neuro-precompensator (신경망 전치보상기를 갖는 확대 I-PD제어기의 설계)

  • 하홍곤
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.4 no.3
    • /
    • pp.619-625
    • /
    • 2000
  • A many control techniques have been proposed in order to improve the control performance of the discrete-time domain control system. In the position control system, the output of a controller is generally used as the input of a plant but the undesired noise is included in the output of a controller. Therefore there is a need to used a precompensator for rejecting the undesired noise. In this paper, The expanded I-PD control system with a precompensator is constructed. The precompensator and I-PD controller are designed by a neural network and these coefficients are changed automatically to be a desired response of system when the response characteristic of system is changed under a condition.

  • PDF

Financing Strategy for Port Development in response to Unification of South and North Korea (남북한 통일대비 항만개발을 위한 재원조달 전략)

  • 임종길;이태우
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
    • /
    • 2000.04a
    • /
    • pp.16-32
    • /
    • 2000
  • This paper aims at exploring financing methods for port development in response to unification of South and North Korea. In so doing, methods of port financing employed by major countries have been enumerated. Major financing sources for the two Korea, among others, taxes, public bond, public administration fund, establishment of harbour maintenance tax, port development tax, port development fund, Civil Economic Cooperation Fund of South and North Korea, and Fund for Port Development of North Korea and, fund for cooperation of South and North Korea, Economic Development Cooperation Fund, borrowing of foreign capital, project financing, domestic civil capital investment, foreign capital investment, application of cross-subsidization principle, etc. were suggested.

  • PDF

Effects of POLIGONI MULTIFORI RADIX on Imunosuppretion Induced by Methotrexate in Rat (하수오(何首烏)가 methotrexate로 유도된 흰쥐의 면역기능저하(免疫機能低下)에 미치는 영향(影響))

  • Kim Il-Young;Lee Sang-Jae;Kim Kwang-Ho
    • Journal of Society of Preventive Korean Medicine
    • /
    • v.4 no.2
    • /
    • pp.152-169
    • /
    • 2000
  • To examine the effects of Polygonum multiflorum on white rats with deteriorated immunity caused by methotrexate, first of all, methotrexate was fed to the rats once a day for 4 days. After the immune response of the rats are dereriorated, dried extracts of Polygonum multiflorum mixed in water was fed to the white rats once a day for 144days. The next conclusion was made by examining the rates of B-cells and T-cells of the peripheral blood and the changes in rates of CD4+ T-cells and CD8+ T-cell of the blood sampled from the spleen and peripheral region . Polygonum multiflorum has an effect of increasing immune responses on white rats with deteriorated immunity caused by MTX. Especially the count of CD4+ T-cells of the peripheral blood and the count of CD4+ T-cell of the spleen proved the significant effect o( increasing immune responses statistically . Verification of the effects of the Polygonum multiflorum should be made through comparitive .studies using various immune response indexes. Also additional studies for a modern and practicible application of Polygonum multiflorum seems to be needed.

  • PDF

Comparison of Colorimetry and HPLC Method for Quantitative Analysis of Chitooligosaccharide (키토올리고당의 측정법으로 비색법과 HPLC법의 비교)

  • Kang, Kil-Jin;Cho, Jung-Il
    • Korean Journal of Food Science and Technology
    • /
    • v.32 no.4
    • /
    • pp.788-791
    • /
    • 2000
  • The quantitative analysis of chitooligosaccharide was compared to using colorimetry and HPLC method. HPLC method required less than 10mins per sample in analytical time of glucosamine and its the recovery rate was 98.4% (10 mg/ml, w/v). Also there was no the effects of interfering substances(false positive response) by HPLC method. The content of chitooligosaccharide in processed chitooligosaccharide products obtained using HPLC showed lower levels compared to colorimetry. Thus, HPLC method was more sensitive, effective and precise than the colorimetry currently used to determine the glucosamine of chitooligosaccharide.

  • PDF

Spinach Root-Tissue Based Amperometric Biosensor for the Determination of Hydrogen Peroxide (시금치 뿌리 조직 바이오센서를 이용한 과산화수소의 정량)

  • Lee, Beom-Gyu;Yoon, Kil-Joong;Kwon, Hyo-Shik
    • Analytical Science and Technology
    • /
    • v.13 no.3
    • /
    • pp.315-322
    • /
    • 2000
  • The response characteristics of the bioelectrode developed by the co-immobilization of spinach root tissue and ferrocene in a carbon paste matrix for the amperometric determination of hydrogen peroxide were evaluated. In the range of electrode potential examined (-0.3~0.0V vs. Ag/AgCl). the response time was relatively short ($t_{95%}=11.8$ sec) and it responded in the wide range of pH. Also, its detection limit was $2.25{\times}10^{-6}M$ (S/N=3) and a relative standard deviation of the measurements which were repeated 15 times using $1.0{\times}10^{-3}M$ hydrogen peroxide was 1.87%. The bioelectrode sensitivity decreased to 40% of the original value in 19 days of continuous use.

  • PDF

Effects of frequency-amplitude modulation of silver spike point electrical stimulation on epinephrine and norepinephrine in human (인체에 적용한 주파수-진폭 변조 은-침점 전기자극이 Epinephrine과 Norepinephrine에 미치는 효과)

  • Choi, Young-Deog;Lim, Jong-Soo;Kim, Soon-Ja
    • Journal of Korean Physical Therapy Science
    • /
    • v.7 no.2
    • /
    • pp.567-577
    • /
    • 2000
  • In human body, catecholamines, such as epinephrine and norepinephrine, can be increased anxiety, blood pressure and pain etc. The inhibitory effects of TENS, electroacupuncture and massage on the release of epinephrine, norepinephrine from sympathetic nerve endings has already been known. However, the effects of silver spike point stimulation on the catecholamines was not well understood. Therefore, the purpose of this study was to characterize the SSP-induced inhibitory effects of catecholamines. The following results were obtained. (1) The studies on urinary catecholamines released that the levels of epinephrine and norepinephrine of continue type SSP stimulation group were significantly lower than those in the control group in human in vivo. (2) The dose-response curves of epinephrine and norepinephrine in rat aortic smooth muscle strips were increased dose dependent manner respectively. However, the contractile response of norepinephrine in rat aortic smooth muscle strips were slightly differentiated. It is concluded that the SSP stimulation reflects to the inhibitory effects of epinephrine and norepinephrine in men. Especially, we believe that the amplitude-frequency modulation, such as continue type a)1d frequency modulation type, of SSP stimulation plays a role in regulating catecholamines.

  • PDF

Extraction of Phenolic Compounds from grape Seed Using Supercritical $CO_2$ and Ethanol as a Co-solvent (초임계 이산화탄소와 에탄올 보조용매를 이용한 포도씨로부터의 페놀성 화합물의 추출)

  • Lee, Won-Young;Chang, Kyu-Seob;Choi, Yong-Hee
    • Food Science and Preservation
    • /
    • v.7 no.2
    • /
    • pp.177-183
    • /
    • 2000
  • A supercritical fluid extraction was performed for the extraction of phenolics from grape seeds which up to now have been discarded. The optimum condition for extraction process was predicted through response surface methodology using central composit experimental design. The extraction amount of grape seed phenolics was increased by increasing extraction temperature, pressure, and concentration of co-solvent (ethanol). The optimum extraction conditions were 84.83$^{\circ}$C, 51.50MPa and 1.27% ethanol. The yield of phenolics using SFE was higher with 3 folds than ethanol and 4 folds than hexane but less than 80% methanol. In the respects of food poisoning, the approved solvents were restricted to ethanol and hexane. So, SFE for extraction of phenolics could be powerful alternative method for solvent extraction.

  • PDF

Evaluation of Thermal Comfort on Protective Clothing Worn in an Radiation Power Plant

  • Kim, Eun-Joo;Han, Myung-Sook;Lee, Won-Ja
    • The International Journal of Costume Culture
    • /
    • v.3 no.1
    • /
    • pp.30-40
    • /
    • 2000
  • The purpose of this research was to device thermal comfort model for radiation power plant workers in protective clothing. Three fabrics commonly used in protective workwear were made into coveralls of identical design and were evaluated by adult healthy males in four simulated work environment. It was investigated between the physiological response and subjects comfort according to environmental variance and clothing types. The of simulated work enviro mensent was controlled under four different humidity and temperature of each type. (Temperature 20±1℃, RH 40∼70%±5%, Temperature 30±1℃, RH 40∼70%±5%) An index of physiological response was connected with the thermal comfort designed. Mean skin temperature, skim temperature, Axillasy temperature ear canal temperature, clothing climate, total sweat, blood pressure, and R-R interval were be evaluated. Skin temperature difference ocurring during exercise and rest were significant only with respect to time and regions of the body, This despite physical differences in the three coveralls, particulary mass statistically experiment. Also, an index of subject wearing sensation was designed for thermal comfort after investigation determined the kind of clothes and the type of environment. As a result of this research, two types of multiple regressions was deviced to estimate thermal comfort of the protective clothing.

  • PDF

Proline Accumulation in Vigna angularis Seedlings Under Salt Stress

  • Lee, Hee-Kyung;Hong, Jung-Hee
    • Environmental Sciences Bulletin of The Korean Environmental Sciences Society
    • /
    • v.4 no.1
    • /
    • pp.51-57
    • /
    • 2000
  • Changes in the proline accumulation of ten-day-old seedlings of Vigna angularis in response to NaCl treatment were monitored. The proline content increased gradually both with an increase in the exposure time to salt stress and in a concentration-dependent manner. The increased proline accumulation was stronger in the shoots than in the roots. The salt stress by itself resulted in a significant inhibition of the chlorophyll content. Pre-treatment with proline before salinization lasting 48 h did not significantly affect the endogenous proline level in the roots, in contrast, a considerable increase of proline was observed in the shoots. The application of exogenous proline to the seedlings increased the endogenous proline content and improved the root and shoot growth under saline conditions. Detached leaves also exhibited an increased proline level in response to the applied NaCl, however, at a lower magnitude than in the intact seedlings. The proline alleviated the inhibitory effect of the NaCl in a concentration-dependent manner, thereby suggesting that salinity is a strong inducer of proline accumulation. In addition, abscisic acid eliminated the inhibitory effect of the salt salinity, thereby indicating a protective role on salinity stress and a regulatory role in proline synthesis. Accordingly, it would appear that proline may be involved in salt tolerance.

  • PDF