• Journal of the Korean Geographical Society
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• v.37 no.3
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• pp.237-246
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• 2002

This study classified wintertime bioclimatic zones of South Korea based on daytime and nighttime distribution of wind chill index calculated from climate data during the coldest month for latest 30 years (1971- 2000). The results show that the winter daytime and nighttime wind chill index were influenced by climatic factors such as elevation, land-sea breeze, topology, and sea currents etc. as well as climatic components such as temperature, wind speed, and sunshine, so that South Korea was divided into five bioclimatic zones; Cool day- cold night zone, Keen day- Cold night zone, Keen day-Very Cold night zone, Cold day and night zone, and Cold day-Extremely Cold night zone. Especially, coasts and island areas, except for south coast of Korea, shows Keen bioclimatic response during daytime and Very Cold bioclimatic response during nighttime. This indicates that coasts and island areas, except for south coast of Korea are affected by moonson and land-sea breeze. In addition, highly elevated Daegwallyeong shows Cold bioclimatic response during daytime and Extremely Cold during nighttime due to the influence of adiabatic temperature lapse rate and monsoon. This study offers basic data necessary to make decisions concerning insulation such as clothing and architect etc. by classifying winter bioclimatic zones of South Korea based on various daytime and nighttime distribution of wind chill.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.44 no.4 s.316
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• pp.70-77
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• 2007

Two kinds of QMF(Quadrature Mirror Filter) pairs are used in JPEG2000 standard, which don't have QMF distortions. However, the QMF pairs have the main disadvantages such that there are gentle roll-off rate, ripples in the passband and unequal band decomposition. In this paper, Maxflat(maximally flat) QMF pairs with a half-band gain are proposed for overcoming these problems. Maxflat QMF pairs are realized due to generalized closed-form formulas, and the filters have maximally flat response in the passband/stopband as well as sharp roll-off rate in the transition band. Comparing proposed filters and JPEG2000's filters in frequency domain, it is found that proposed filters have better performance JPEG2000's filters. Moreover, Maxflat QMF pairs show stopband-attenuation exceeding 200 dB almost everywhere.

• The Journal of Korean Obstetrics and Gynecology
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• v.31 no.2
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• pp.31-48
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• 2018

Objectives: This study was performed to observe the correlations between the results of ABR-2000 and DSOM / 3D-MAC to evaluate the feasibility of ABR-2000 as a oriental medical diagnostic criteria. Methods: We studied 547 women visiting ${\bigcirc}{\bigcirc}$ hospital from December 2012 to June 2015. The subjects were categorized in two groups, 'Hypotonia' and 'Non-Hypotonia' by the result of ABR-2000 and assessed the result of DSOM, 3D-MAC for each group. The differences of pulse wave factors by group also studied. Results: 1. There was no significant difference between two groups about the output frequency of pathogenic factors in DSOM while the result showed the higher correlation in Hypotonia group in terms of the companion tendency of pathogenic factors and syndromes formed by the combination of pathogenic factors. 2. The pulse waves of Hypotonia group were mostly slow, weak, tense and stiff than Non-Hypotonia group. Conclusions: 1. In Hypotonia group, yin deficiency (陰虛) factor was frequently accompanied and consumption (虛損) of various organs based on the yin deficiency (陰虛) was observed. It means chronic and severe condition of exhaustion syndrome (虛勞). 2. The result of 3D-MAC also means pathological feature of yin syndrome (陰 證) and consumption (虛損). Besides, lower scores of Body Surface Area (BSA), body weight, and Body Mass Index (BMI) were associated with body weakness (體瘦), a symptom of exhaustion syndrome (虛勞).

• Journal of Acupuncture Research
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• v.17 no.4
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• pp.28-40
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• 2000

Objectives : This study was purposed to investigate the effect of honey bee venom aqua-acupuncture on decreased immune response by its production from Korea, North America and China. Methods : ICR-mouse was exposed with four minute sublethal 60Co- $\gamma$ -ray irradiation onto the body and got a series of each country's 0.1 ml honey bee venom aqua-acupuncture to Choksamni(ST36) every other day for three times. Thereafter the numbers of WBC, delayed type hypersensitivity, hemagglutinin titers, hemolysin titers, quantitation of T-cell and B-cell, lymphocyte transformation, natural killer cell activity, interleukin-2 productivity and interferon productivity were measured. Results : The numbers of WBC, delayed type hypersensitivity, hemagglutinin titers, hemolysin titers, quantitation of T-cell and B-cell and lymphocyte transformation were increased respectively with statistical significance in Korean, North American and Chinese honey bee venom aqua-acupuncture groups as compared with the control group. The natural killer cell activity was increased with statistical significance in Korean honey bee venom aqua-acupuncture group, and Interleukin-2 productivity and interferon productivity were not shown any statistical significance in all experimental groups as compared with the control group. Conclusions : According to the results, honey bee venom aqua-acupuncture has significant effect on decreased immune response, and Korean bee venom can be substituted for North American and Chinese one.

• Journal of Fisheries and Marine Sciences Education
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• v.12 no.2
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• pp.142-151
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• 2000

The studies on the electronic control fuel injection system for a DI diesel engine have done for reducing the exhaust emission and improving fuel consumption. The electronic control fuel injection system is classified into a common rail system, a unit injector system and a high pressure injection system. The characteristics of these systems are largely depends on the operating characteristics of its solenoid that have high speed on-off operation. In order to improve these characteristics of fuel injection system, it is necessary to design the optimal shape of solenoid and select the input method of its power source. It was proposed HELENOID, COLENOID, DISOLE, and Multipole Solenoid in the studies of design for the optimal shape of solenoid. The studies on the energizing method, input method for power of solenoid were dealt with the conventional energizing method, the chopping method and the pre-energizing method. In order to find out the high response characteristics of solenoid, it is necessary to test the performance of optimally designed solenoid with a new energizing method. In this paper, the solenoid of multi-pole type with plat armature and its power control unit to control input current by the chopping method designed, and its response tests were performed according to its energizing conditions. As a result, the maximum input current for solenoid was controlled by the period of first stage exciting current and chopping duty ratio of control stage exciting current, and the fastest "on" time was able to get 0.46ms. The conditions of fastest "on" time was 0.3ms for first stage exciting current, 0.16ms for control exciting current and 75% for chopping duty ratio.

• The Korean Journal of Food And Nutrition
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• v.13 no.5
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• pp.419-424
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• 2000

In order to develop the roll bread for diabetes mellitus patients, the roll bread mixed with soybean and barley flour to wheat flour was prepared and followed investigation of physical properties, sensory evaluation and blood glucose response of subjects. When soybean and barley flour was added more than 30%, hardness of mixed roll bread increased more than two times comparing to wheat flour. The roll bread mixed with 10% soybean flour was same in physical properties but was superior in sensory evaluation to wheat flour. While the blood glucose response after intake of roll bread mixed with soybean flour increased more slowly than that after intake of barley or wheat flour, glycemic index of soybean flour decreased. When roll bread was mixed with 10 to 30% soybean flour. the preference was almost same but control ability of blood glucose has improved comparing to adding barley or wheat alone.

• Toxicological Research
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• v.16 no.4
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• pp.317-323
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• 2000

The immunosuppressive effects of thirty nine chemicals chosen by their potential toxicity were evaluated using a three-step testing method. The immunotoxicity test method developed in this study consisted of three simple assays of lymphoproliferation, mixed leukocyte response, and interleukin (IL)-2 production. The first step was mitogen-induced proliferation assay. Ten chemicals showed the inhibitory effects on the mitogen (lipopolysaccharide or concanavalin A)-induced proliferation in dose-dependent manners. The second step was mixed lymphocyte response. This step crosschecked the growth-suppressive effects detected at the first step. All of 10 chemicals, which showed suppression of lymphoproliferation, also exhibited the suppressive effects on the mixed lymphocyte response in the similar range of chemical concentration. The third step was planned to determine whether or not this growth suppression was mediated through an early activation of T-cell, which could be represented with IL-2 production. Six out of 10 chemicals decreased the interleukin-2 production in the similar concentration range used in the step 1 and 2. These results suggest that those 6 chemicals might have their targets on the signal transduction path-way toward the IL-2 production. In the meantime the other 4 chemicals might have their targets after the IL-2 production signal. Taken all together, the three-step test would be simple, fast, and efficient to deter-mine whether or not the chemical has immunosuppressive effects.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2000.04a
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• pp.290-300
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• 2000

One of the most important topics in attentional and emotional modulation of cardiac responses is time course of cardiac chronotropic response. The reason lies in dual innervation of heart, which leads to occurrence of several phases of cardiac response during exposure to affective stimuli, determined by the balance of sympathetic and parasympathetic influences. Cardiac chronotropic reactivity thus represents quite effective measure capable to trace the moment when attending and orienting processes (i.e., sensory intake of stimulus) prime relevant behavioral response (ile., emotion with approach or avoidance tendencies). The aim of this study was to find the time course of heart rate (HR) responses typical for negative (disgust, surprise, fear, anger) and positive (happiness, pleasant erotic) affective pictures and to identify cardiac response dissociation for emotions with different action tendencies such as "approach" (surprise, anger, happiness) and "avoidance" (fear, sadness, disgust). Forty college students participated in this study where cardiac responses to slides from IAPS intended to evoke basic emotions (surprise, fear, anger, sadness, disgust, happiness, pleasant-erotic). Inter-beat intervals of HR were analyzed on every 10 sec basis during 60 sec long exposure to affective visual stimuli. Obtained results demonstrated that differentiation was observed at the very first 10s of exposure (anger-fear, surprise-sad, surprise-erotic, surprise-happiness paris), reaching the peak of dissociation at 30s (same pairs plus surprise-disgust and surprise-fear) and was still effective for some pairs (surprise-erotic, surprise-sad) even at 50s and 60s. discussed are potential cardiac autonomic mechanisms underlying attention and emotion processes evoked by affective stimulation and theoretical considerations implicated to understand the role of differential cardiac reactivity in the behavioral context (e.g., approach-avoidance tendencies, orienting-defense responses).

• Korean Journal of Veterinary Research
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• v.40 no.4
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• pp.769-775
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• 2000

This study was investigated the ovarian response following superovulation treatment at different day of diestrus. The criterion for the presence or absence of a dominant follicle based on their morphological examination. Dominant follicle was puntured 48 hrs before the oneset of superovulation treatment by ultrasonography guided aspiration needle. Superovulation was induced by subcutaneous administration of FSH twice a day for 4 day in a decreasing regimen. There was no significant different between presence of dominont follicle and progesterone concentration/diameter of corpus luteum in HanWoo. Number of corpus luteum of donor after superovulation treatment was not significantly different in FSH administration at day 9, 11 and day 13 of estrus($14.5{\pm}4.5$, $15.5{\pm}5.6$ and $11.0{\pm}5.5$, respectively). But, the diameter of CL was significantly correlate(R2 = 0.757) with progesterone levels on day of superovulatory induction. After 7 days of artificial insemination, the embryos at 7 days were collected by uterine flushing after dominant follicle aspiration and superovulation treatment, and evaluated their quality by morphological criteria. Fifty five embryos with excellent, good and fair grade were transferred into 24 recipient cows. Seventeen offsprings, 1 of triplet, 4 of twins and 6 of singlet, were yield from 10 recipient cow. In conclusion, the present study showed that 1) dominant follicle can be determined by ultrasonography with rectal palpation by morphological evaluations, 2) superovulation response after follicular aspiration was not differ at day 9, 11 and 13 of estrus, 3) dominant follicle did not affect to progesterone concentration and diameter of CL, and 4) diameter of CL was significantly correlate to the level of progesterone concentrations in HanWoo.

• Archives of Pharmacal Research
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• v.23 no.5
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• pp.507-512
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• 2000

This study set out to improve the physical and pharmaceutical characteristics of the present formulation using an appropriate experimental design. The work described here concerns the formulation of the dispersible tablet applying direct compression method containing roxithromycin in the form of coated granules. In this study $2^3$ factorial design was used as screening test model and Central Composite Design (CCC) associated with response surface methodology was used as optimization study model to develop and to optimize the proper formulation of roxithromycin dispersible tablet. The three independent variables investigated were functional excipients like binder (X1), disintegrant (X2) and lubricant (X3). The effects of these variables were investigated on the following responses: hardness (Y1), friability (Y2) and disintegration time (Y3) of tablet. Three replicates at the center levels of the each design were used to independently calculate the experimental error and to detect any curvature in the response surface. This enabled the best formulations to be selected objectively. The effect order of each term to all response variable was X3> X2> Xl> X1＊X2> X2＊X2> X2＊X3> X3＊X3> Xl＊X3> Xl＊Xl and model equations on each response variables were generated. Optimized compositions of formula were accordingly computed using those model equations and confirmed by following demonstration study. As a result, this study has demonstrated the efficiency and effectiveness of using a systematic formulation optimization process to develop the tablet formulation of roxithromycin dispersible tablet with limited experiment.