• Title/Summary/Keyword: RESPONSE 2000

Search Result 1,863, Processing Time 0.027 seconds

Antioxidant Defense and Lipid Peroxide Level in Liver and Kidneys of Lead Exposed Rats

  • Patra, R.C.;Swarup, D.;Dwivedi, S.K.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.13 no.10
    • /
    • pp.1433-1439
    • /
    • 2000
  • An experiment was carried out with 48 IVRI 2CQ rats 6-8 week old, weighing 50-100 g, to study the effect of lead exposure on antioxidant defense, lipid peroxide level, status of thiol groups and concentration of lead in the liver and kidneys at the end of the exposure and also after withdrawal of lead administration. Twenty four rats were given lead at a daily dose rate of 1 mg lead/2 ml of distilled water/kg body weight as lead acetate solution intraperitoneally for a period of 30 days. Another 24 control rats received 2 ml of sterile normal saline solution (0.85% NaCl)/kg body weight in an identical manner. A many-fold increase in concentration of lead was associated with a non-significant (p>0.05) decrease in the activities of superoxide dismutase (SOD) in the liver (27%) and kidneys (12%) and catalase in kidneys (22%). A significant (p<0.05) increase in lipid peroxide level was recorded in the liver (40%) compared with control values. There were significant (p<0.05) decreases in the total thiol and protein bound thiol contents in liver and an increase in non-protein bound thiol groups in the kidneys of lead exposed rats. During the 10 day observation period after withdrawal of lead administration, no significant change was observed with respect to any of the above parameters indicating that a 10 day withdrawal period was not enough for restoration of normality. It is concluded that the magnitude of response and the resultant changes in the lipid peroxide concentration, and the activities of SOD and catalase were not identical in the liver and kidneys of lead-exposed rats.

Effects of Dietary Protein Sources and Levels on Heat Production and Thermoregulatory Responses of Sheep Exposed to a High Ambient Temperature

  • Sudarman, A.;Ito, T.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.13 no.11
    • /
    • pp.1523-1528
    • /
    • 2000
  • Four Suffolk ewes were used in Latin Square switch over design to study the effects of varying levels and sources of protein on heat production and thermoregulatory responses at daytime high ($33^{\circ}C$ temperature. They were fed Italian ryegrass hay supplemented with fishmeal and/or urea, providing three different levels of crude protein (CP) (low/unsupplemented: 7.9, medium: 11.6, and high: 15.8%) at $1.5{\times}maintenance$. Feeds were distributed at 0900 (30%) and 1700 (70%). Urea diet caused higher heat production and increased vaginal temperature compared to fishmeal and fishmeal-urea mix diets. Time spent standing, skin temperature and respiration rate of sheep fed urea were similar with those of sheep fed fishmeal. Sheep fed diet with low CP level had higher heat production, increased vaginal and skin temperature than sheep fed diet with medium CP content. Sheep on high CP diet produced significantly more heat than sheep fed medium CP diets. Their vaginal temperatures were similar with those of sheep fed medium CP diet but lower than those of sheep fed low CP diet. Respiration rates of sheep and time spent by them for standing on all diets did not differ significantly. These results suggest that urea is inferior protein supplement for thermoregulation of animal at hot environment, as it induced higher heat production than fishmeal and fishmeal-urea mix. Thermoregulatory response on fishmeal-urea mix diet was similar to fishmeal diet. Increasing CP of the diet from low to medium gives advantage for thermoregulation of animal. Increasing CP further to high level was not beneficial as it resulted in the responses of sheep similar to those on low protein diet.

A Study on the Cooling Center Manual of Facility and Maintenance for Extreme Heat Disaster (폭염재난에 대응하는 Cooling Center 시설 및 운영기준에 관한 연구)

  • Kim, Jin-Wook
    • Journal of the Korean Society of Hazard Mitigation
    • /
    • v.8 no.4
    • /
    • pp.17-22
    • /
    • 2008
  • Including heat wave, Climate change caused 150,000 casualty in 2000 and heat waves are meteorological events that pose a serious threat to human health. A heat wave is defined as "a period of abnormally and uncomfortably hot and usually humid weather". There is a need for the prevention of health effects due to weather and climate extremes. This study intends to propose the necessity of Response System to correspond to extreme heat. And this research focused on Cooling Center manual of facility and maintenance for extreme heat disaster. It would be useful to be planned based on community and to be taken a role as an E.O.C.(Emergency Operating Center). As a conclusion elderly watching system and the requirements regional cooling center facility was proposed.

Dependence of Nutrient Supplying Capacity on Chemical reactions of Paddy Soil (논토양 화학특성 변화와 양분공급력과의 관계)

  • Kim, Yoo-Hak;Kim, Myung-Sook;Kang, Seong-Soo;Jun, Hee-Joong
    • Korean Journal of Soil Science and Fertilizer
    • /
    • v.42 no.spc
    • /
    • pp.33-39
    • /
    • 2009
  • The practice of supplying nutrients for paddy soil with sustaining human health and ecological soundness is to utilize indicators considering soil chemical reactions. The long-term basis experiment of fertilizer and amendment of paddy soil and an experiment of yield response of soil types on nitrogen level from 2000 till 2002were used to search indicators of nutrient supplying capacity related to soil chemical reactions. Chemical reactions of paddy soil was composed of dissociating and/or adsorbing nutrients and of decomposing soil organic matter (SOM) into $H^+$, $e^-$, $CO_2$ in paddy soil. The indicators of nutrient supplying capacity, which were established by considering soil chemical reactions, were SOM or soil protein for nitrogen and available phosphate for phosphorus and cation exchangeable capacity (CEC) and exchangeable potassium for potassium. Korea has used fertilizer recommendation equations established with the indicators of nutrient supplying capacity for paddy soil.

Effects of Bisphenol A on Dams during Lactation Period in Rats

  • Kim, Pan-Gyi;Leu, Jae-Hong;Kang, Hee-Joo;Kim, Jeong-Hyun
    • Proceedings of the Korean Environmental Health Society Conference
    • /
    • 2003.06a
    • /
    • pp.171-173
    • /
    • 2003
  • Bisphenol A (4,4'-isopropylidenediphenol, C$\_$15/H$\_$16/O$_2$) is the monomer used in the manufacture of polycarbonate. Polycarbonate, in turn, is used in a wide array of plastic products, with new applications continuously being developed. Also it has been used to produce epoxy resins and polycarbonate plastics for food container. This study was carried out to investigate the effects of bisphenol A on lactation period to dams and F1, Sprague-Dawley females were mated with on 2:1 ratio basis. Various doses of bisphenol A (0, 2, 20, 200, and 2,000 $\mu\textrm{g}$/kg) were daily administered to females for 21 days after parturition. Dams and offsprings were sacrificed at the time of weaning. The results were as follows, 2000 $\mu\textrm{g}$/kg of bisphenol A decreased the dams' body weight at post-partum 18 days and also 200 and 2000 $\mu\textrm{g}$/kg of bisphenol A decreased the body weight of neonates at the days of post-partum 21 days. Bisphenol A increased the relative weights of liver and spleen in male offsprings, depending on the doses. But female offsprings showed high relative organ weights of ovaries, and low relative organ weights of uterine in a some dose-response manners. High dose of bisphenol A induced low viability of neonates exposed during lactation period. The dams treated with bisphenol A showed prematured estrous stage. Bisphenol A was recovered about 21.2% average in serum of dams, and also in offsprings'. The results indicate that the bisphenol A induces estrous cycle during lactation period in dams, also reaches to the of offspring through breast milk. Thus bisphenol A exopsed to dams and neonates via lactation induces some estrogenic and toxic effects.

  • PDF

Measuring Thermo-luminescence Efficiency of TLD-2000 Detectors to Different Energy Photons

  • Xie, Wei-min;Chen, Bao-wei;Han, Yi;Yang, Zhong-Jian
    • Journal of Radiation Protection and Research
    • /
    • v.41 no.2
    • /
    • pp.179-183
    • /
    • 2016
  • Background: As an important detecting device, TLD is a widely used in the radiation monitoring. It is essential for us to study the property of detecting element. The aim of this study is to calculate the thermo-luminescence efficiency of TL elements. Materials and Methods: A batch of thermo-luminescence elements were irradiated by the filtered X-ray beams of average energies in the range 40-200 kVp, 662 keV $^{137}Cs$ gamma rays and then the amounts of lights were measured by the TL reader. The deposition energies in elements were calculated by theory formula and Monte Carlo simulation. The unit absorbed dose in elements by photons with different energies corresponding to the amounts of lights was calculated, which is called the thermo luminescent efficiency (${\eta}^{(E)}$). Because of the amounts of lights can be calculated by the absorbed dose in elements multiply ${\eta}^{(E)}$, the ${\eta}^{(E)}$ can be calculated by the experimental data (the amounts of lights) divided by absorbed dose. Results and Discussion: The deviation of simulation results compared with theoretical calculation results were less than 5%, so the absorbed dose in elements was calculated by simulation results in here. The change range of ${\eta}^{(E)}$ value, relative to 662 keV $^{137}Cs$ gamma rays, is about 30% in the energy range of 33 keV to 662 keV, is in accordance by the comparison with relevant foreign literatures. Conclusion: The ${\eta}^{(E)}$ values can be used for updating the amounts of lights that are got by the direct ratio assumed relations with deposition energy in TL elements, which can largely reduce the error of calculation results of the amounts of lights. These data can be used for the design of individual dosimeter which used TLD-2000 thermo-luminescence elements, also have a certain reference value for manufacturer to improve the energy-response performance of TL elements by formulation adjustment.

Optimization of Active Tendon Controlled Structures by Efficient Solution of LQR Control Gain (LQR 제어이득의 효율적 산정에 의한 능동텐던 구조물의 최적화)

  • Cho, Chang-Geun;Kyun, Jun-Myong;Jung, In-Kju;Park, Moon-Ho
    • Journal of Korean Association for Spatial Structures
    • /
    • v.8 no.4
    • /
    • pp.73-80
    • /
    • 2008
  • The objective of current study is to develop an optimization technique for the seismic actively controlled building structures using active tendon devices by an efficient solution of LQR control gain. In order to solve the active control system, the Ricatti closed-loop algorithm has been applied, and the state vector has been formulated by the transfer matrix and solved by a numerical technique of the trapezoidal rule. The time-delay problem has been also considered by phase compensation. To optimize the performance index, the ratio of the weighted matrix is the design variable, allowable story drift limits of IBC 2000 and tendon forces have been applied as restraint conditions, and the optimum control program has been developed with the algorithm of the SUMT technique. In examples of the optimization problem of eight stories shear buildings, it is evaluated that the optimum controlled building is more suitable in the control of earthquake response than the uncontrolled system and can reduce the performance index to compare with the controlled system with a constant ratio of the weighted matrix.

  • PDF

Design and Implementation of Distributed Metadata Searching System using XML Web Service and JDBC (XML 웹서비스와 JDBC를 이용한 분산 메타데이터 검색 시스템의 설계 및 구현)

  • Choe, Hyunjong;Hwang, Sungwuk;Kim, Taeyoung
    • The Journal of Korean Association of Computer Education
    • /
    • v.7 no.2
    • /
    • pp.25-34
    • /
    • 2004
  • Sixteen provincial Research Institute of Education and Science(RISE) in the country have provided good qualified multimedia educational materials that was produced by some special skilled teachers to elementary, middle and high school teachers using web services. And moreover KERIS and KICE have also produced educational materials and have a plan to integrate distributed multimedia educational materials that RISE produced. The development of KERIS's KEM metadata in 2001 and the making of educational material metadata of RISE is the first step of integration plan. These metadata can be used to make integration plan possible. But before taking integration plan, the study of how to integrate and manage it should be performed. Therefore, this paper introduces the technique of XML web service and JDBC with 3-tier system as the method of integrate distributed educational material metadata. The evaluation shows these two methods have similar response time with MS SQL Server 2000 and Oracle 9i. Thus, we conclude that JDBC and XML web service can be the proper solution to search XML-formatted metadata.

  • PDF

Additional Evidence on the Market Reaction to Stock Option Grants (스톡옵션 부여공시에 따른 주가상승효과 재검토)

  • Sul, Won-Sik;Kim, Soo-Jung
    • The Korean Journal of Financial Management
    • /
    • v.20 no.1
    • /
    • pp.61-92
    • /
    • 2003
  • As an extension of previous researches with the conclusion that the announcement of adopting stock options generates positive abnormal returns, this paper examined whether the abnormal return changes over time or varies depending on the number of stock options granted. Empirical analysis was made to find whether the announcement of stock option awards has the same response in the stock market from the early days when stock option plans had been introduced in the Korean stock market till today when it was widespread. Results indicate that the announcement effect had been on a gradual decline since 2000. In addition, it is found that if a company announces stock option awards several times, the abnormal return gradually declines in proportion of the number of stock options granted. This implies that as the stock option awards become widespread, the positive effect that the announcement of adopting stock options generates as news has been on a relatively steady decrease. In short, it leads to a conclusion that the more companies grant stock options, and the more stock options a company announces, the less impact it has on the increase in the firm's value.

  • PDF

Self-control of high rise building L-shape in plan considering soil structure interaction

  • Farghaly, A.A.
    • Coupled systems mechanics
    • /
    • v.6 no.3
    • /
    • pp.229-249
    • /
    • 2017
  • A new technique to mitigate irregular buildings with soil structure interaction (SSI) effect subjected to critical seismic waves is presented. The L-shape in plan irregular building for various reasons was selected, subjected to seismic a load which is a big problem for structural design especially without separation gap. The L-shape in plan building with different dimensions was chosen to study, with different rectangularity ratios and various soil kinds, to show the effect of the irregular building on the seismic response. A 3D building subjected to critical earthquake was analyzed by structural analysis program (SAP2000) fixed and with SSI (three types of soils were analyzed, soft, medium and hard soils) to find their effect on top displacement, base shear, and base torsion. The straining actions were appointed and the treatment of the effect of irregular shape under critical earthquake was made by using tuned mass damper (TMD) with different configurations with SSI and without. The study improve the success of using TMDs to mitigate the effect of critical earthquake on irregular building for both cases of study as fixed base and raft foundation (SSI) with different TMDs parameters and configurations. Torsion occurs when the L-shape in plan building subjected to earthquake which may be caused harmful damage. TMDs parameters which give the most effective efficiency in the earthquake duration must be defined, that will mitigate these effects. The parameters of TMDs were studied with structure for different rectangularity ratios and soil types, with different TMD configurations. Nonlinear time history analysis is carried out by SAP2000 with El Centro earthquake wave. The numerical results of the parametric study help in understanding the seismic behavior of L-shape in plan building with TMDs mitigation system.