• The Korean Journal of Pain
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• v.13 no.2
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• pp.137-142
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• 2000

Background: Systemic or intrathecal administration of gabapentin has been shown to reverse various pain states. However, until now, the effect of intracerebroventricular (ICV) gabapentin to noxious stimuli has not been reported. The authors' aim of this study was to determine the effect of ICV gabapentin on the inflammatory nociceptive model, formalin test, in rats. Methods: ICV catheters were implanted under halothane anesthesia. For the nociceptive test, $50{\mu}l$ of 5% formalin was subcutaneously injected into the hindpaw. The effect of ICV gabapentin, administered 10 min before formalin injection, were examined on flinching, mean arterial pressure and heart rate evoked by a injection of formalin. Results: Injection of formalin into the paw resulted in a biphasic flinching and cardiovascular response. ICV gabapentin produced a dose-dependent suppression of the flinching and mean arterial pressure response during phase 1. In contrast, in phase 2, ICV gabapentin did not attenuate the pain behavior. ICV gabapentin did not affect on the baseline mean arterial pressure and heart rate. Conclusions: ICV gbapentin was effective for the acute noxious stimulus but it had no effect on the facilitated states induced by tissue injury.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.15 no.2
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• pp.127-140
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• 2011

Objectives: Acupuncture has been shown to relieve pain and modulate biological function by stimulating the organ-specific meridians and enhances parasympathetic activity and suppresses sympathetic activity. The aim of this review is to summarize and understand the effects of acupuncture on autonomic nervous system. Methods: We reviewed a total of 29 studies published from 2000 to 2010 searched by PueMed and various domestic oriental medicine journals to obtain acupuncture studies related with ANS. Each article was classified by ANS measurement index and reviewed for study objectives, outcomes, acupuncture points, experimental and control interventions. Results: In the study of acupuncture about EEG, HRV, SCR, the experiment results are not the same by acupoints. Although same acupoint the results differ by subject's condition. But the study showed some clear tendency. In brief, in normal states acupuncture enhanced either vagal or sympathetic tone depending on the stimulated acupuncture point sites. On the other hand, most of studies demonstrated that acupuncture restored the autonomic dysfunctions in various kinds of tired or stressful states. Conclusions: We reviewed studies that contributed to an understanding of the effects and mechanisms of acupuncture on autonomic nervous system. Although the relationship between acupuncture and ANS response is still uncertain, acupuncture could be a excellent treatment method for modulating autonomic dysfunction.

• Progress in Medical Physics
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• v.11 no.1
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• pp.19-27
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• 2000

In order to predict the propagation of road traffic noise over level terrain, this paper presents the model of the simple monopole and dipole source. Excess attenuations by ground acoustic impedance with continuity are investigated by outdoor experiments. In this results, the propagation of road traffic noise is affected by the acoustic impedance properties of the ground surface over which the noise travels, particularly when the receiver position is close to the surface. These results are then used to derive sound pressure level contours for the attenuation with distance of the equivalent energy level received from passing vehicle. The percentage of deep sleep and the number of wakings are studied for continuous traffic noise. The hearing loss and sensitivity threshold shift is investigated by changing the various parameters such as the effects of aging and noise exposure. Evaluation of the response of human to traffic noise is discribed. It is shown that exposure to excessive noise can cause temporary loss of hearing that may become permanent if the exposure is prolonged or intense.

• Radiation Oncology Journal
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• v.12 no.2
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• pp.201-207
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• 1994

To objectively compare the response of the palliative radiotherapy in bone metastatic patients which decreases pain and prevents pathologic fractures, we introduced and applied the RTOG pain and narcotic measure system. From Oct in 1991 to July in 1993, thirty-two patients with painful bone metastases, 17 of them were solitary lesions and others were multiple lesions, were treated with mainly 6 MV photon otherwise 15 MV photon. Radiation doses to bone metastatic sites ranged about from 2000 to 4600cGy. Responses of radiation therapy were compared with days of pre-RT, RT finish, 3, 6, 9 months after the start of RT and solitary versus multiple lesions and follow up scores according to the RTOG measure system. Survival analysis was done. Pain and narcotic score of the entire patients were 7.3, 7.8 at the pre-RT period and 2.6, 3.9 at the immediate or 2 weeks after RT, which was $64{\%},\;50{\%}$ decrement compared with the pre-RT score, Pain scores of 3, 6 and 9 months after the beginning of irradiation were 3.6, 3.7 and 3.3. The best response found in the breast and prostate primaries was $84\%,\;78\%$ decrement of pain score as compared with pre-RT score(statistically insignificant). Median survival was 5.5 months and mean survival was 5 months. We conclude that the RTOG pain and narcotic measure system is relatively effective scale in the comparison of before and after palliative irradiation to the painful bone metastatic sites but more detailed parameters will be required in the narcotic scoring system. More aggressive but less or similiar toxic radiotherapy is needed in the patients having relatively long life expected time.

• Proceedings of the Korean Society of Crop Science Conference
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• 2000.11a
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• pp.3-11
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• 2000

The Asian summer monsoon has a profound social and economic impact in East Asia and its surrounding countries. The monsoon is basically a response of the atmosphere to the differential heating between the land mass of the Asian continent and the adjacent oceans. The atmospheric response, however, is quite complicated due to the interactions between the atmospheric heat sources, land-sea contrast, and topography, The occurrence of extreme summertime floods in Korea, Japan, and China in 1998 and 1999 has highlighted the range of variability of the East Asian summertime monsoon circulation and spurred interest in investigating the cause of such extreme variability. While ENSO is often considered a prime mechanism responsible for the unusual hydrological disasters in East Asia, understanding of the connection between ENSO and the East Asian monsoon is hampered by their dynamic complexities. Along with a recent phenomenon of weather abnormalities observed in many parts of the globe, Korea has seen its share of increased weather abnormalities such as the record-breaking heavy rainfalls due to a series of flash floods in the summers of 1998 and 1999, following devastating Yangtze river floods in China. A clear regime shift is found in the tropospheric mean temperature in the northern hemisphere middle latitudes and the surface temperature over the Asian continent during the summer with a sudden warming since 1977. Either decadal climate variation or climate regime shift in the Asian continent is evident and may have altered the characteristics of the East Asian summer monsoon. Considering the summertime rainfall amount in Korea is overall increased lately, the 1998/99 heavy rainfalls may not be isolated episodes related only to ENSO, but could be a part of long-term climate variation. The record-breaking heavy summer rainfalls in Korea may not be direct impact of ENSO. Instead, the effects of decadal climate variation and ENSO may be coupled to each other and also to the East Asian summer monsoon system, while their individual impacts are difficult to separate.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2000.04a
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• pp.370-379
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• 2000

Autonomic responses were analyzed in 323 college students exposed to visual stimulation with Korean Affective Picture System (KAPS). Cardiac, vascular and electrodermal variables were recorded during 30 sec of viewing affective pictures. The same slides intended to elicit basic emotions (fear, anger, surprise, disgust, sadness, happiness) were presented to subjects in 2 trials with different experimental context. The first time slides were shown without any instructions (passive viewing), while during the second with instruction to exert efforts to magnify experienced emotion induced by pictures (active viewing). The aim of the study was to differentiate autonomic manifestations of emotions elicited by KAPS stimulation and to identify the role of instructed emotional engagement on physiological response profiles. The obtained results demonstrated reproducibility of responses in both trials with different contexts. Pairwise comparison of physiological responses in emotion conditions revealed the most pronounced differentiation for "ear-anger" and "fear-sadness" pairs (in electrodermal and HR variability parameters). "Fear-surprise" pair was also well differentiable. The typical response profile for all emotions included HR acceleration (except happiness and surprise), an increase of electrodermal activity, and a decrease of pulse volume. Higher cardiovascular and electrodermal reactivity to fear observed in this study, e.g., as compared to data with IAPS as stimuli, can be explained by cultural relevance and higher effectiveness of KAPS as stimuli, can be explained by cultural relevance and higher effectiveness of KAPS in producing certain emotions such as fear in Koreans.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.33 no.2
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• pp.115-118
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• 2000

The production of cultured coho salmon (Oncorhpchus kisutoh) in Korea has being increased year after year. Smolt being reared in freshwater suffer transferring into seawater and are farmed in cages for fattening. This handling processes including transportation, confinement into cages are unavoidable stress to fish in salmon farming and often end up to mass mortality, This study aimed to investigate the impact of handling process on the stress responses of coho salmon. The indicator of stress was measured by cortisol to be a first response, and for the second response test, glucose, triBlyceride, cholesterol, lactate and electrolyte of $K^+, Na^+, Cl^-$ in serum and the activities of alanine aminotrtnferase (ALT), aspartate aminotransferase(AST) and lactate dehydrogenase (LDH) were analyzed. As a result, the concentration of cortisol, glucose as well as LDH activity were significantly increased, whereas others showed no difference comparing with control group. It obviously demonstrated that handling process made fish stressful.

• Earthquakes and Structures
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• v.12 no.1
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• pp.67-77
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• 2017

In this paper, it is aimed to present a comparative study about the structural behavior of tall buildings consisting of different type of materials such as concrete, steel or timber using finite element analyses and experimental measurements on shaking table. For this purpose, two 1/60 scaled 28 and 30-stories wooden building models with $40{\times}40cm$ and $35{\times}35cm$ ground/floor area and 1.45 m-1.55 m total height are built in laboratory condition. Considering the frequency range, mode shapes, maximum displacements and relative story drifts for structural models as well as acceleration, displacement and weight limits for shaking table, to obtain the typical building response as soon as possible, balsa is selected as a material property, and additional masses are bonded to some floors. Finite element models of the building models are constituted in SAP2000 program. According to the main purposes of earthquake resistant design, three different earthquake records are used to simulate the weak, medium and strong ground motions. The displacement and acceleration time-histories are obtained for all earthquake records at the top of building models. To validate the numerical results, shaking table tests are performed. The selected earthquake records are applied to first mode (lateral) direction, and the responses are recorded by sensitive accelerometers. Comparisons between the numerical and experimental results show that shaking table tests are enough to identify the structural response of wooden buildings. Considering 20%, 10% and 5% damping rations, differences are obtained within the range 4.03-26.16%, 3.91-65.51% and 6.31-66.49% for acceleration, velocity and displacements in Model-1, respectively. Also, these differences are obtained as 0.49-31.15%, 6.03-6.66% and 16.97-66.41% for Model-2, respectively. It is thought that these differences are caused by anisotropic structural characteristic of the material due to changes in directions parallel and perpendicular to fibers, and should be minimized using the model updating procedure.

• Journal of Korean Society of Steel Construction
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• v.12 no.6
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• pp.661-670
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• 2000

To investigate the characteristics of the dynamic response of long-span cable-stayed bridges due to various dynamic loadings likes moving traffic loads, two different 3-D cable-stayed bridge models are considered in this study. Two models are exactly the same in structural configurations but different in finite element discretization. Modal analysis is conducted using the deformed dead-load tangent stiffness matrix. A new concept was presented by using divided a cable into several elements in order to study the effect of the cable vibration (both in-plane and swinging) on the overall bridge dynamics. Futhermore case of asymmetric traffic loading clustered in one direction are also considered to study the torsional response of the bridge. The result of this study demonstrates the importance of cable vibration on the overall bridge dynamics.

• The Journal of Korean Association of Computer Education
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• v.3 no.2
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• pp.31-37
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• 2000

We developed a test bank system which dynamically adjusts to students' achievement levels. In order to dynamically calculate the student's achievement level, our system uses the question-response theory which is usually adopted to CAT. The system proposes appropriate questions depending on the students' achievement levels so that they can do self-directed and individualized learning. The system consists of pre-test, main learning, and review stages. In the pre-test stage, the intellectual level of the student is examined to determine the starting point in the main stage. In the main learning stage, individualized learning is performed. Finally, a review session is added to re-examine the questions that the student gave wrong answers. The output from the learning process of the system is not the usual test scores but the level of the student's intellectual ability which is produced through the question-response theory. The intellectual ability level index objectively measures the degree of improvement of the student's learning ability.