• BMB Reports
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• v.45 no.8
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• pp.482-487
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• 2012

To identify the novel inhibitors of endoplasmic reticulum stress-induced cell death, we performed a high throughput assay with a chemical library containing a total of 3,280 bioactive small molecules. Cyclosporine A and bromocriptine were identified as potent inhibitors of thapsigargiin-induced cell death (cut-off at $4{\sigma}$ standard score). However, U74389G, the potent inhibitor of lipid peroxidation had lower activity in inhibiting cell death. The inhibition effect of cyclosporine A and bromocriptine was specific for only thapsigargin-induced cell death. The mechanism of inhibition by these compounds was identified as modification of the expression of glucose regulated protein-78 (GRP-78/Bip) and inhibition of phosphorylation of p38 mitogen activated protein kinase (MAPK). However, these compounds did not inhibit the same events triggered by tunicamycin, which was in agreement with the cell survival data. We suggest that the induction of protective unfolded protein response by these compounds confers resistance to cell death. In summary, we identified compounds that may provide insights on cell death mechanisms stimulated by ER stress.

• Proceedings of the Korea Water Resources Association Conference
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• 2006.05a
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• pp.1506-1510
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• 2006

현재 기상청에서 제공하는 강수자료는 정시자료로서 수문학적 의미의 임의지속시간 강수자료라 볼 수 없다. 따라서 이러한 정시자료를 임의지속시간 강수자료로 변환하여 사용하여야 한다. 이러한 환산계수는 국외에서는 Weiss(1964), Dwyer와 Reed(1995) 등에 의하여 제시되어졌고, 국내에서는 김규호 등(1988)등이 환산계수를 제시한 바 있다. 그렇지만 기존 연구의 자료들은 목측에 의한 자료로서 많은 불확실성을 가지고 있다. 최근 관측기기의 발달에 의하여 기상청에서는 1분 단위의 관측 자료를 구축하였다. 따라서 본 연구에서는 이러한 1분 단위 강수자료를 이용하여 수문학적 의미의 임의지속시간 강수자료를 적출하여 보다 정확하게 강수자료의 환산계수(Adjustment factor)를 구축하는데 목적이 있다. 본 연구에서는 서울지방 7개 자동기상관측소(AWS:Automatic Weather Station)에서 관측된 6개년(2000년${\sim}$2005년) 1분 강수자료를 이용하여 고정시간 연 최대강수량과 임의시간 연 최대강수량간의 관계를 연구하였다. 1분 강수자료를 이용하여 고정시간과 임의지속시간에 대한 연 최대치 강수 계열을 구축.도시한 후 선형회귀분석에 의해 선정된 계수를 환산계수로 제시하였다. 고정시간 1시간부터 24시간까지의 최대강수량과 임의시간 간격 최대강수량의 비율을 분석한 결과 환산계수는 지속시간이 증가함에 따라 비선형적으로 감소하는 것으로 나타났다. 이러한 관계를 이용하면 정시 강수자료를 보다 정확하게 임의지속시간 강수자료로 환산할 수 있을 것으로 판단된다.

• Journal of Ecology and Environment
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• v.40 no.1
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• pp.1-4
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• 2016

Recent ocean warming near the Korean peninsula and our lack of knowledge of an important vertebrate group, the sea snakes, encouraged us to clarify this part of Korea's regional fauna. We re-examined photographs that had been used to report the slender-necked sea snake (Hydrophis melanocephalus) in 1995. We discovered it was misidentified. To determine the correct identity of the sea snake, we studied 13 original photographs taken at the collecting site in Sooyoung Bay, Busan-si, in 1995 and determined the snake to be Laticauda semifasciata based on enlarged ventral scales, definitive for Laticaudinae sea snakes, and internasal scales, pale blue body color, divided rostral scale, and evident "V"-shaped stripes on the body trunk, definitive for L. semifasciata. Therefore, the snake caught 30 years ago in Korean waters should be considered the first record of a Laticaudinae sea snake in Korean waters. L. semifasciata is listed as near threatened setting the stage for urgently needed studies of sea snakes in Korea and supporting those currently underway.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.2
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• pp.215-221
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• 2009

In recent, there has been progressed in various ways of research and development about a ubiquitous telemetry reading, but several problems are arising the reliability of reading value, power supply and so on. These issues were solved by using the RF module and digital pulse meter with photocoupler. Realized by this study, a telemetry reading system, utilizing RF and CDMA telecommunication, and check in real time the state of water leakage by managing the distinct usage data. In addition, the users can check it in person, and it can minimize the public enmities. Further, as a part of the silver industry fur constantly growing senior population, it might be introduced as safety supervision system.

• Journal of Biosystems Engineering
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• v.14 no.2
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• pp.128-136
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• 1989

The purpose of this study was to develop a computer operated automatic drip irrigation system for application in vinyl-house cultivation. The results can be summarized as follows: 1) The T-type ice compensation wire was used to measure the temperature. The voltage level measured up to 0.02 volt was used as input to an 8-bit A/D converter. 2) A specially devised tensiometer was used to content the watering system. When the needle of the pressure gauge reaches the lower threshold position it turns on the pumping system and turns off when it reaches higher threshold position. 3) In order to use the multiple gypsum blocks for one transducer, reed relays and a D/O board were used to make the sequential switching possible. 4) It was possible to automate the trickle irrigation system for the whole growth period of vinyl-house crops with the help of microcomputer. 5) In terms of furrow irrigation, the irrigation water consumption was the smallest, 2.8 times less than conventional method of surface trickle irrigation, 3.4 times less than subsurface trickle irrigation method. 6) In terms of productivity of cucumber, there was a drop in productivity when compared to furrow irrigation method, 7.2% for surface trickle irrigation, 27.4% for subsurface irrigation method.

• Journal of the Korea Furniture Society
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• v.18 no.1
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• pp.70-83
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• 2007

Rattan furniture is strips of cane around the frame that consists of wisteria, bamboo and wood. The materials are originally from Southeast Asia, and the material of domestic Rattan goods is Korean wisteria. Rattan, which is strong and elastic, is often used for craft materials, and it also retains the original feel of the material with great touch. It is beautiful and suitable for expressing curves. It is shiny, light in weight, easy for cleaning and ventilation. Rattan furniture is unique product made by human hands and nature and is an environment friendly well-being furniture. The use examples of these domestic rattan furnitures is condensed as below. First, the materials of rattan product is wisteria, rice straw, bush clover wood, reed and bamboo. Second, the use of rattan product which is made of domestic wisteria is limited to farming equipments and living wares. Third, the materials of rattan furniture differs in domestic made and foreign made product. As is the characteristics of timbers growing in warmer climates of Korea, it has many twist and strong and it is not straight in length so it is hard to manufacture into and use as furniture also it is hard to acquire right size for the material.

• Journal of The Korean Society of Grassland and Forage Science
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• v.20 no.4
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• pp.309-316
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• 2000

The objective of this experiment was to evaluate chemical composition, dry matter(DM) digestibility, DM intake, relative feed value(RFV) and hay grade of imported roughage which was collected by wholesale dealer at Chungnam province in 1999. Experimental roughages includes 8 kinds of imported hays(com stover bale, tall fescue straw, green cell, bermudagrass straw, reed camarygrass straw, alfalfa bale, sugarcane bale and oat hay) and mixture hay(contro1) which was harvested at Chungnam National University experimental field. Compared with mixture hay(contro1) except for alfalfa bale, crude protein of most imported roughage was low, but NDF, ADF, cellulose and lignin compound were high. Futhermore, DM digestibility, DM intake, RFV and hay grade of imported roughage except for alfalfa bale was significantly lower than those of mixture hay(control)(P<0.05). Therefore, it is necessary to evaluate the economic value in the aspect of quality for the imported roughages. (Key words : Imported roughage, RFV, Hay grade, Nutritive value)

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.6
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• pp.2207-2213
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• 2010

A new scheme for variable structure control design which is based on eigenvalues assignment of sliding mode is developed. In conventional methods, generally, specific type of system matrix like canonical or regular form is required to construct a switching surface. Furthermore, the methods are not explicit. The new method in this paper solved the problems. No special type of system matrix is required and very explicit. It is shown that the switching surface can be constructed and determined uniquely without any dependency on the system form. The proposed method is based on the fact that the dynamics of sliding mode is determined by system zeros. Finally, a numerical example is given to verify the validity of the results studied in this paper.

• Journal of Korean Neurosurgical Society
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• v.42 no.2
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• pp.149-152
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• 2007

Authors report a very rare case of primary Hodgkin's lymphoma limited to the cerebellum. A 64-year-old female patient presented with headache, nausea, and vomiting. Magnetic resonance imaging of the brain revealed a nodular enhancing mass in the left cerebellar hemisphere. Tumor was removed totally with retromastoid suboccipital approach. Diagnosis was Hodgkin's lymphoma of mixed cellularity type, consisting of a dense mixed inflammatory infiltrate containing scattered large atypical mononuclear Hodgkin's cell and multinucleated Reed-Sternberg cells. Systemic work-up for the Hodgkin's lymphoma was followed with negative result. Postoperative radiation therapy was given and the patient is disease-free at 16 months after the operation.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.10C
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• pp.605-613
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• 2011

In most digital communication systems over the noisy channel, some form of forward error correction scheme is employed for reliable communications. If one wants to recover the transmitted message without any knowledge of the error correcting codes employed, it is of utmost importance to figure out and reconstruct the error correcting codes. In this paper, we propose two algorithms of reconstructing linear cyclic codes from the corrupted received bit sequence, one for general linear binary cyclic codes and the other for Reed-Solomon codes. For two algorithms, we ran computer simulations and the performances are shown to be superior to those with the conventional LWM method.