• 한국응용곤충학회지
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• 제30권3호
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• pp.174-179
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• 1991

1986~1990년에 3년근 인삼포장에서 참검정풍뎅이 유충에 의한 춘기 피해 양상을 조사한 결과 인삼포장의 바깥쪽일수록 피해가 심하였는데 이는 참검정풍뎅이 자성충의 dirks 이동 습성 때문으로 보인다. 3령 유충에 의한 3년근 인삼의 피해부는 뿌리 동례의 상부, 중부, 하부 또는 뿌리 전체였으며 드물게 지하부 줄게에도 피해가 있었다. 섭식기 3령층의 평균 서식 깊이는 인삼 유묘, 2년근, 3년근, 쑥에서 각각 3.2cn, 5.6cm, 6.6cm, 4.9cm 였다. 춘기의 참검정풍뎅이 유충에 의한 인삼의 피해는 주러 5월 중순에서 7월 상순에 발생하였고 강우량이 증가할 경우 피해가 일시적으로 감소하는 것으로 보였다.

• Journal of Ginseng Research
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• 제37권1호
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• pp.54-63
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• 2013

Ginsenoside Rd is a primary constituent of the ginseng rhizome and has been shown to participate in the regulation of diabetes and in tumor formation. Reports also show that ginsenoside Rd exerts anti-oxidative effects by activating anti-oxidant enzymes. Treatment with ginsenoside Rd decreased nitric oxide and prostaglandin $E_2$ ($PGE_2$) in lipopolysaccharides (LPS)-challenged RAW264.7 cells and in ICR mouse livers (5 mg/kg LPS; LPS + ginsenoside Rd [2, 10, and 50 mg/kg]). Furthermore, these decreases were associated with the down-regulations of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 and of nuclear factor (NF)-${\kappa}B$ activity in vitro and in vivo. Our results indicate that ginsenoside Rd treatment decreases; 1) nitric oxide production (40% inhibition); 2) $PGE_2$ synthesis (69% to 93% inhibition); 3) NF-${\kappa}B$ activity; and 4) the NF-${\kappa}B$-regulated expressions of iNOS and COX-2. Taken together, our results suggest that the anti-inflammatory effects of ginsenoside Rd are due to the down-regulation of NF-${\kappa}B$ and the consequent expressional suppressions of iNOS and COX-2.

• 한국측량학회지
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• 제40권4호
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• pp.275-292
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• 2022

기후변화 감시에 위성 자료 활용을 위해 GCOS (Global Climate Observing System)는 시공간 해상도, 시간 변화에 따른 안정성, 불확실도 등의 요구사항을 제시하고 있다. 천리안위성 2A호의 경우, 센서의 한계로 인해 산출물들이 공간해상도 조건에 충족하지 못하는 경우가 많다. 따라서 본 연구에서는 영상융합 기법들을 천리안위성 2A호 영상에 적용하여 산출물 생성 시 활용될 수 있는 최적의 기법을 찾고자 한다. 이를 위해 CS (Component Substitution), MRA (Multiresolution Analysis), VO (Variational Optimization), DL (Deep Learning)에 포함되는 총 6가지 영상융합 기법을 활용하였다. DL의 경우 합성적(Synthesis) 특성 기반 방법을 훈련자료 구축에 사용하였다. 합성적 특성 기반 방법의 과정은 PAN (Panchromatic)과 MS (Multispectral) 영상의 공간해상도 차이만큼 두 영상의 해상도를 낮춰 융합 영상을 생성한 후 원본 MS 영상과 비교한다. 합성적 특성 기반 방법은 공간해상도를 저하시킨 PAN 영상과 MS 영상 간 기하 특성이 같아야 사용자가 원하는 수준의 융합 영상을 제작할 수 있다. 하지만, 훈련자료 구축 시 비유사성이 존재하기에 이를 최소화하는 방법으로 무작위 비율을 활용한 PSGAN 모델(PSGAN_RD)을 추가로 활용하였다. 융합 영상의 검증은 일관성(consistency) 및 합성적 특성 기반 정성적, 정량적 분석을 수행하였다. 분석 결과, 영상융합 알고리즘 중 GSA가 공간 유사도를 나타내는 평가지수에서 가장 높은 수치를 보였으며, 분광 유사도를 나타내는 지수들은 PSGAN_RD 모델의 정확도가 가장 높았다. 융합 영상의 공간 및 분광 특성을 모두 고려한다면 PSGAN_RD 모델이 천리안위성 2A호 산출물 제작에 가장 최적일 것으로 판단하였다.

• 지역사회간호학회지
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• 제16권4호
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• pp.404-414
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• 2005

Objectives: The present study proposed to evaluate 1st-month and 3rd-month health status, depression, self-efficacy and medical expenses of a community-based health promotive self-management program for old Koreans. Method: Participants in the CDSMP were selected from elders in a community health center through convenient sampling. The program included a 3-hour session per week for 14 weeks. Outcomes of evaluation in the 1st month and the 3rd month included modified Self-rated Health Status Scale, Center for Epidemiologic Studies Short Depression Scale, Self-Efficacy for Managing Chronic Disease 6-item Scale, and 1-item Medical Expenses Scale. Results: Self-rate health scores increased significantly just after the intervention (16.22), in the 1st month (17.57) and in the 3rd month (19.04) (x2=32.06. p=.000); Depression scores (reversed) also increased significantly just after the intervention (6.04), in the 1st month (7.75) and in the 3rd month (8.39) ( $x^2=29.92$. p=.000); Self-efficacy score increased significantly just after intervention (12.87) but it decreased in the 1st month (12.73) and in the 3rd month (12.04). But all of the three scores were still higher than those before the intervention (8.65) ($x^2=32.42$. p=.000): Medical expense score decreased at the end of the intervention (1.57) but the cost score increased in the 1st month (2.48) and in the 3rd month (2.39) ($x^2$=7.81. p=.050). Conclusion: CDSMP is effective in increasing self-rate health and self-efficacy and in decreasing depression in the Korean elderly. However, no significant effect of the program was observed in decreasing the medical cost of the Korean elderly.

• 대한한방내과학회지
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• 제23권2호
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• pp.244-252
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• 2002

Functional dyspepsia refers to upper abdominal pain or discomfort with or without symptoms of early satiety, nausea, or vomiting with no definable organic cause. In this study, we recognized that dyspepsia was decreased with herbal medication (Banhabakchulchunma-tang) and acupuncture therapy. And we aimed to evaluate the Gastrointestinal Symptoms Rating Scale (GSRS) in these cases. The GSRS indicated that Oriental medicine treatment could be effective in the Functional dyspepsia. And it is helpful in decreasing symptoms of patients and in improving quality of life.

• 한국임상수의학회지
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• 제13권2호
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• pp.108-113
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• 1996

The effect of aqua-acupuncture of total saponin on the recovery of liver function in -intoxicated rats was exemined. Rats were divided into normal, control and three experimental groups (As-I group : aqua-acupuncture of saline to Gansu locus and Aa-III group : aqua-a-cupuncture of total saponin to blank locus at the thigh). Changes of some serum biochemical parameters (ALT, AST and ALP, total protein and albumin, and albumin/globulin (A/G) ratio) were determined. Serum ALT activities were increased by $CCI_{4}$T and decreased in all aqua-acupuncture groups compared with the control group. Aa-I group showed significant decrease of ALT activities on the 2nd (P<0.05) and 3rd (P<0.05) day, respectively. Aa-II group showed significant decrease on the 3rd day (P<0.05) day. Serum AST activities were increased by $CCI_{4}$T and decreased in all apua-acupuncture groups compared with the control group. Aa-I group showed significant decrease on the 1st (P<0.05), 2nd (P<0.001) and 3rd (P<0.001) day, respectively. Aa-II group showed significant decrease on the 3rd (P<0.001) day. Aa-III group showed significant decrese on the 1st (P<0.05) and 3rd (P<0.001) day, respectrvely. Serum ALP activities were increased by $CCI_{4}$T and decreased in all aqua-a-cupuncture groups compared with the control group. Aa-I group showed significant decrease on the 3rd (P<0.01) day. Total protein, albumin and A/G ratio were decreased by $CCI_{4}$T and increased in all aqua-acupuncture groups compared with control group. Aa-I group showed significant increase only on the 3rd day in albumin (P<0.01). It was thought that the aqua-acupuncture of total saponin to Gansu locus was effective on the recovery of liver function in $CCI_{4}$T-intoxicated rats.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제21권1호
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• pp.28-33
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• 2018

Purpose: To evaluate the efficacy of synbiotic formula with partial whey hydrolysate and high magnesium content in infants presenting with functional constipation. Methods: Sixty-five infants with functional constipation were included. Forty infants were treated during one month with parental reassurance and the intervention formula and were compared to a control group of 25 infants treated with parental reassurance only. Parents completed a quality of life (QoL) questionnaire at baseline and during the last week of the study. Results: At inclusion, stool characteristics and QoL were similar in both groups. The control group was slightly older than the intervention group ($7.5{\pm}3.9$ vs. $6.2{\pm}3.6$ weeks). At onset, stool composition was "hard and tight" (Bristol stool scale 1 and 2) in all infants. After one month, stool composition remained unchanged in the control group except in two infants that developed "creamy" stools (Bristol stool scale type 3 and 4). In the intervention group, stools remained "hard and tight" in 27.5%, and became "creamy" in 47.5%, "loose" (Bristol stool scale type 5) in 22.5% and "watery" (Bristol stool type 6 and 7) in 2.5%. The benefit of the intervention formula was estimated to be "very important" in 70%. The median scores for QoL improved significantly in the intervention group for all parameters and for one in the control group. Conclusion: The intervention formula significantly improved functional constipation resulting in a better QoL of the parents and infants.

• Korean Journal of Radiology
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• 제21권1호
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• pp.58-67
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• 2020

Objective: Third-generation dual-source computed tomography (3rd-DSCT) allows dynamic myocardial CT perfusion imaging (dynamic CTP) with a 10.5-cm z-axis coverage. Although the increased radiation exposure associated with the 50% wider scan range compared to second-generation DSCT (2nd-DSCT) may be suppressed by using a tube voltage of 70 kV, it remains unclear whether image quality and the ability to quantify myocardial blood flow (MBF) can be maintained under these conditions. This study aimed to compare the image quality, estimated MBF, and radiation dose of dynamic CTP between 2ndDSCT and 3rd-DSCT and to evaluate whether a 10.5-cm coverage is suitable for dynamic CTP. Materials and Methods: We retrospectively analyzed 107 patients who underwent dynamic CTP using 2nd-DSCT at 80 kV (n = 54) or 3rd-DSCT at 70 kV (n = 53). Image quality, estimated MBF, radiation dose, and coverage of left ventricular (LV) myocardium were compared. Results: No significant differences were observed between 3rd-DSCT and 2nd-DSCT in contrast-to-noise ratio (37.4 ± 11.4 vs. 35.5 ± 11.2, p = 0.396). Effective radiation dose was lower with 3rd-DSCT (3.97 ± 0.92 mSv with a conversion factor of 0.017 mSv/mGy∙cm) compared to 2nd-DSCT (5.49 ± 1.36 mSv, p < 0.001). Incomplete coverage was more frequent with 2nd-DSCT than with 3rd-DSCT (1.9% [1/53] vs. 56% [30/54], p < 0.001). In propensity score-matched cohorts, MBF was comparable between 3rd-DSCT and 2nd-DSCT in non-ischemic (146.2 ± 26.5 vs. 157.5 ± 34.9 mL/min/100 g, p = 0.137) as well as ischemic myocardium (92.7 ± 21.1 vs. 90.9 ± 29.7 mL/min/100 g, p = 0.876). Conclusion: The radiation increase inherent to the widened z-axis coverage in 3rd-DSCT can be balanced by using a tube voltage of 70 kV without compromising image quality or MBF quantification. In dynamic CTP, a z-axis coverage of 10.5 cm is sufficient to achieve complete coverage of the LV myocardium in most patients.

• 한국잠사학회:학술대회논문집
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• 한국잠사학회 2003년도 제46회 춘계 학술연구 발표회
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• pp.40-40
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• 2003

Recombinant plasmids harboring heterologous genes coding enhanced green fluorescent protein (EGFP) and erythropoietin (EPO) were transfected and expressed in Drosophila melanogaster S2 cells. Stably transformed cell populations expressing EGFP or monkey EPO were isolated after 4 weeks of selection with hygromycin B. (omitted)

• 대한한방내과학회지
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• 제1권1호
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• pp.78-84
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• 1976

The SIB ZUN DAE BO TANG is one of the prevailing tonics appeared at first time on TAE PYUNG HOE MIN HAW ZE GUK BANG in Song’s dynasty and have been widely used up to now. To observe the metabolic effects of Thioacetamide from the SIB ZUN DAE BO TANG, the following experiment was performed. 1. The activation of G.O.T. and G.P.T. to blood serum have been decreased when Thioacetamide was administrated into the rabbit. 2. The coefficiency of the SIB JUN DAE BO TANG appears in 3 hours after administrate and it decreases gradually along with it’s time(1st, 2nd, 3rd day) but the coefficiency of the G.P.T. was more apparent on 2nd, 3rd and 5th day. 3. When administrating Thioacetamide, the total amount of cholesterol grows rapidly up to 3rd day and it continuously grows after the 3rd day. But when administrating SIB ZUN DAE BO TANG, the cholesterol amount in blood grows up to 3rd day, but it decreases gradually after it on the other day. The conclusion of the above experiments shows that the prescription (SIB ZUN DAE BO TANG) improves the metabolic deficiency and the recovery and remedy of diseases.