• Title/Summary/Keyword: RBC value

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Antioxidant and Antihemolytic Activities of Ethanol Extracts of Carpesii Fructus and Farfarae Flos (학슬 및 관동화 에탄올 추출물의 항산화 및 항용혈 효과)

  • Kang, Hyun Ju;Kim, Hong-Jun;Jeong, Seung-Il;Kim, Hyeon Soo;Jeon, In Hwa;Mok, Ji Ye;Shim, Jae-Suk;Jang, Seon Il
    • The Korea Journal of Herbology
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    • v.28 no.3
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    • pp.25-31
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    • 2013
  • Objectives : To develop a natural antioxidant and anti-hemolytic agents, we investigated the effects of ethanol extracts of Carpesii Fructus and Farfarae Flos. Methods : Aerial parts of Carpesii Fructus and Farfarae Flos were extracted with 80% ethanol. Antioxidant activity of Carpesii Fructus or Farfarae Flos extract was evaluated by employing three different assays, i.e., 1,1-diphenyl-2-picryl hydrazyl (DPPH), 2,2'-azino-bis (3-ethylbenzthiazoline-6-suphonic acid) diammonium (ABTS) scavenging and reducing power activities. Also, anti-hemolytic activity of Carpesii Fructus or Farfarae Flos extract was determined using [2,2'-azobis (2-methylpropionamidine) dihydrochloride (AAPH)]-induced hemolysis, glutathione (GSH) depletion and malondialdehyde (MDA) formation in normal rat red blood cells (RBC) or plasma. Results : The extracts obtained from Carpesii Fructus and Farfarae Flos dose-dependently increased the scavenging activity on DPPH- or ABTS-induced radicals and the reducing power activities. Carpesii Fructus and Farfarae Flos were similar to the scavenging activity and the reducing power of butylated hydroxy anisole effect at high concentration ($1,000{\mu}g/mL$). RBC oxidative hemolysis and plasma MDA formation induced by AAPH were significantly suppressed by the extracts of Carpesii Fructus and Farfarae Flos in a dose-dependent manner. Also, Carpesii Fructus and Farfarae Flos extracts prevented the depletion of cystosolic antioxidant GSH in RBCs. Carpesii Fructus generally had better than the free radical scavenging activity, the reducing power and anti-hemolytic effects of Farfarae Flos. Conclusions : These results suggest that Carpesii Fructus and Farfarae Flos may have value as the potential antioxidant and anti-hemolytic medicinal plant.

Sources of Trade Balance Dynamics in Korea

  • Kim, Jiwoon;Yu, Jongmin
    • Journal of Korea Trade
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    • v.26 no.2
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    • pp.21-44
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    • 2022
  • Purpose - This study quantifies sources of trade balance dynamics over the business cycle in Korea. Specifically, we quantify the relative importance of domestic and foreign factors on trade balance dynamics using a small open economy real business cycle (SOE-RBC) model and provide policy implications for stabilization policies. Aggregate productivity and interest rate spreads are considered domestic factors affecting the trade balance. A world interest rate (the U.S. interest rate) is considered a foreign factor. Design/methodology - Following Neumeyer and Perri (2005), we build the SOE-RBC model with three types of shocks: aggregate productivity, interest rate spread, and world interest shocks. The model is estimated by the generalized method of moments (GMM) using relevant business cycle statistics. The estimated model is used for quantifying the relative importance of domestic and foreign factors on trade balance dynamics in Korea. Findings - Our main findings can be summarized as follows: 85.64% of the trade balance fluctuations in Korea are explained by domestic factors, the remaining 14.35% by foreign factors. Particularly, trade balance dynamics are mostly accounted for by the change in aggregate productivity shocks (85.58%). World interest rate shocks considerably explain trade balance (14.35%), whereas the role of interest rate spread shocks that represent domestic risks is limited (0.08%). Although aggregate productivity is key in explaining trade balance dynamics in Korea, interest rates still have an essential role. This is because aggregate productivity changes induce interest rate spread variations and, thus, the trade balance significantly. The results suggest that government policies mitigating fluctuations in aggregate productivity would be effective for stabilization policies in Korea by reducing the trade balance volatility. Originality/value - Existing studies on the emerging market business cycle examine mostly Latin American countries, and the main object of the studies is the volatility of consumption rather than trade balance dynamics. Conversely, our study examines Korea rather than Latin American countries. Additionally, we examine sources of trade balance dynamics, which are relatively more important in Korea, rather than those of the volatility of consumption. Hence, we estimate the model to explicitly match moments related to trade balance in the data.

STUDIES ON THE MATHEMATICAL KINETICS FOR THE REMOVABLE MOVING SCREEN MEDIA-ACTIVATED SLUDGE PROCESS (회전형 반고정망 활성슬럿지 공법의 수학적 해석에 관한 연구 2. 슬럿지 생산량 및 축적과정과 유출수의 수질에 대하여)

  • HAN Ung-Jun;HAN Yeong-Ho
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.12 no.3
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    • pp.175-179
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    • 1979
  • One of the major problems in tile activated sludge system has been difficulty in separating the microbial solids from the treated effluent and in returning them to the aeration tank. Another problem has been the digestion of the excess activated sludge. In constrast, it has not been difficult to separate the microbial solids from the treated effluent from the biological fixed-film systems(RBC process, Trickling Filter, FAST process). These systems have also featured less sludge production. Recently, it was proposed to experiment with the RESMAS process in order to eliminate the settling tank and sludge concentration facilities and to reduce the quantity of excess sludge for final disposal. The effluent quality could be predicted by .the concept of the maximum accumulation capacity. However, the hydraulic characteristics of the screen media in the RESMAS reactor were not dynamic. The object of the present study is to evalute the sludge accumulation rate and effluent quality prediction in the REMSMAS process designed in the dynamic hydraulic structure. This process can eliminate the final sedimentation tank and sludge concentration tank needed in the RBC, CMAS, Trickling Filter and FAST processes. Also, the effluent quality is desirable to compare with other processes. It appeared that the value of the sludge holding capacity was higher than those of the RESMAS and FAST processes, and the periods of the critical operating time were proportional to the substrate hydraulic loadings.

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Integrated System of RBC-lime Precipiatation for Simultaneous Removal of Organics and Nutrients (회전원판공정과 화학침전공정 조합을 이용한 유기물과 질소*인의 동시제거)

  • 박종안;허준무;손부순
    • Journal of Environmental Health Sciences
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    • v.24 no.1
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    • pp.132-140
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    • 1998
  • Laboratory-scale experiments were conducted using a three-stage rotating biological contactor unit followed by lime precipitation and sedimentation with effluent recycle to the first stage. The purpose of this study was to evaluate the effects of hydraulic loadings of 0.031-0.076 $m^3/m^2/d and recycle ratio of 1 to 3 on the simultaneous removal of organics and nutrients from domestic wastewater. Lime was added to maintain pH of 10.4-11.0 in the coagulation-flocculation reactor. Results showed that the highest nitrogen removal rate of 70.5% occurred at the lower hydraulic loading of 0.031 $m^3/m^2/d at a recirculation rate of 300%, and similarly, highest nitrification occurred at the same hydraulic loading and recycle ratio. Concentration of ammonia nitrogen in the effluent was less than 1 mg/l at the same operating conditions for higher nitrogen removal. Whereas, high BOD and COD removal was observed at hydraulic loading rate of 0.054 $m^3/m^2/d, and high removal of organic matter was evident from the consistent low COD and BOD value. Results obtained from the operating condition of higher loading rate, 300% of recycle rate showed the highest removals. Increasing in recycle rate and hydraulic loading rate increased the volatile solids fraction of the sludges generated to the extent of 47% at 0.076 $m^3/m^2/d hydraulic loading and 300% recirculation rate. Since pH in the flocculator was maintained at the pH of 10.4-11.0, above 90% removal of phosphorus was obtained. Average concentration of suspended solids was always maintained over 40 mg/l in the effluent. Therefore an RBC unit operating at a hydraulic loading near 0.031 $m^3/m^2/d with a recycle rate of 300% is a viable and feasible alternate conditions to produce an effluent with relative low organic matter and phosphorus, provided that there is a neutralization unit to control the pH and SS of the effluent.

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Detection Characteristics of a Red Blood Cell Coupled with Micron Magnetic Beads by Using GMR-SV Device (GMR-SV 소자를 이용한 미크론 자성비드와 결합된 적혈구 검출 특성 연구)

  • Lee, Jae-Yeon;Kim, Moon-Jong;Lee, Sang-Suk;Rhee, Jin-Kyu
    • Journal of the Korean Magnetics Society
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    • v.24 no.4
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    • pp.101-106
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    • 2014
  • The glass/Ta(5.8 nm)/NiFe(5 nm)/Cu(2.3 nm)/NiFe(3 nm)/IrMn(12 nm)/Ta(5.8 nm) GMR-SV (giantmagneto-resistance-spin valve) multilayer structure films with a magnetoresistance ratio (MR) of 5.0 % and a magnetic sensitivity (MS) of 1.5%/Oe was deposited by dc magnetron sputtering method. Also, GMR-SV device having a width of $7{\mu}m{\sim}8{\mu}m$ similar to the diameter of RBC (red blood cell) was fabricated by the light lithography process. When RBCs coupled with several magnetic beads with a diameter of $1{\mu}m$ dropped upon the GMR-SV device having MR = 1.06% and MS = 0.3 %/Oe, there is observed the variation of about included of a resistance value of ${\Delta}R=0.4{\Omega}$ and ${\Delta}MR=0.15%$ around a external magnetic field of -0.6 Oe. From these results, the GMR-SV device having the width magnitude of a few micron size can be applied as the biosensor for the analysis of a new magnetic property of hemoglobin inside of RBC combined to magnetic beads.

Effects of Feeding Charcoal Powder and Vitamin A on Growth Performance, Serum Profile and Carcass Characteristics of Fattening Hanwoo Steers (활성탄과 비타민 A의 급여가 거세 한우의 성장, 혈액성상 및 도체 특성에 미치는 영향)

  • Kim, B.K.;Kim, Y.J.
    • Journal of Animal Science and Technology
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    • v.47 no.2
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    • pp.233-242
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    • 2005
  • Effects of supplemental charcoal powder and vitamin A on growth performance, serum profile and carcass characteristics with 24 Hanwoo steers were inves$\ell$ated. The Hanwoo steers were randomly assigned to one of the three dietary treatments: 1) Control(commercial feed), 2) Tl(commercial feed supplemented with 2% charcoal powder and 0.2 % vitamin A), 3) T2(commercial feed with 2 % charcoal powder). In the age 26 month, body weight of control Tl and T2 were 633.8 kg, 621.0 kg, 619.4 kg, respectively, with not significantly different(P> 0.05). The daily weight gain of control was the highest followed by Tl and T2. The contents of vitamin A(retinol) and total cholesterol in the blood of Tl was higher Tl(56.32 $\ell$ / dt, 163.83 mg/ dz) than the other treatment groups(P < 0.05). The average of WBC value in the blood was 6.86-" 9.83 k / ${\mu}\ell$, RBC value was 7.98 - 11.26 k / ${\mu}\ell$ and blood platelet was 236.7 - 287.0 k / ${\mu}\ell$. But The serum profile in blood was not significantly different between control and treatment groups. The carcass grade and characteristics of all treatments in Hanwoo steers were not significantly different except the texture.

Studies on Combined Usage of Combined Preparation of Crude Drugs and Anti-neoplastic Drugs (I) -Alleviative Effect of Combined Usage of Gamisamryungbaekchool-San and cis-Platin on the Side Actions of cis-Platin- (생약복합제제(生藥複合製劑)와 항암제(抗癌劑)의 병용투여(倂用投與)에 관한 연구(硏究) (제1보)(第1報) -가미삼령백출산(加味蔘笭白朮散)과 cis-Platin 병용투여(倂用投與)에 의한 부작용(副作用) 경감(輕減) 효과(效果)-)

  • Kim, Nam-Jae;Hong, Nam-Doo;Cho, Chong-Kwan;Kim, Jin-Sik;Baek, Seung-Hak
    • Korean Journal of Pharmacognosy
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    • v.22 no.3
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    • pp.197-206
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    • 1991
  • The water extract of Gamisamryungbaekchool-San increased the lifespan of mice implanted intraperitoneally with sarcoma 180. Significant depression of lethal toxicity of cis-platin $(45{\mu}M/kg,\;s.c)$ and renal toxicity (indicated by an increase in blood urea nitrogen value and creatinine value) of cis-platin $(35{\mu}M/kg,\;s.c)$ were observed in mice and rats treated with Gamisamryungbaekchool-San. RBC and WBC were significantly decreased in rats treated with cis-platin, and significant depression of hematologic toxicities of cis-platin $(35{\mu}M/kg,\;s.c)$ in rats treated with Gamisamryungbaekchool-San. After all, alleviative effect of the side actions of cis-platin was acknowledged by combined usage of Gamisamryungbaekchool-San and cis-platin.

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Application of Pediatric Hemodialysis System to Experimental Renal Failure in Dogs (실험적으로 유발한 신부전 개에서 소아용 혈액투석기의 적용에 관한 연구)

  • 신현호;김완희;이충호;남치주;권오경
    • Journal of Veterinary Clinics
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    • v.17 no.2
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    • pp.340-345
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    • 2000
  • The purpose of the present study was to evaluate the possibility of application of pediatric hemodialysis system to dogs weighing less than 6 kg. Six healthy dogs (B .W, 3-6 kg) were used_ Experimental end-stage renal failure was induced by bilateral nephrectomy or bilateral ligation of ure-ters. Hemodialysis was performed when blood urea nitrogen (BUN) value increased over 90 mg/dl and every other day thereafter. Daily investigated parameters included clinical clinical signs such as vomiting, fecal appearance and activity and laboratory data such as PCV, WBC, RBC, BUN, creatinine, Ca, P, $Na^+ Cl^-and K^+$During hemodialysis treatment, BUN and creatinine values were measured hourly. Severe vomiting and inappetence were shown 2 days after infliction of kidney disorder and melena and mucous faces were observed 3 days. The signs were not corrected by hemodialysis treatment. Avel- age hemodialysis treatment time was $5.5 {\times} 0.7$,/TEX> hours until BUN value decreased to normal range. Abnor- mal hematological and electrolytes values were reduced within normal levels after hemodialysis treatments. The complications oft hemodialysis included vomiting, nausea, obstruction of intravascular catheter, tremor, seizure, temporary visual loss and continued decrease in PCV It is suggested that pediatric hemedialysis system can be applied to acute renal failure and acute toxicity. Further works on improvements in maintaining patency of catheter and in managing the complications of hemo- dialysis should be conducted.

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Blood and Serum Chemical Values on Deer Bred in Taegu Dalseung Park (사슴의 혈액 및 혈액화학치에 관한 연구)

  • 이근우;장인호;송재찬;이동석
    • Journal of Veterinary Clinics
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    • v.13 no.2
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    • pp.127-129
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    • 1996
  • The study was conducted to determine normal blood and serum chemical values on deer. Normal blood and serum chemical values were studied in 8 healthy deers bred at Dalseung Park in Taegu. The values were analyzed with a blood chemical analyzer and calculated by Chawen's statistical analysis. The blood values of RBC, WBC and PCV were $9.73{\pm}1.19{\times} 10^{6}/{\mu}l, 3.37{\pm}0.88{\times}10^{3}/{\mu}l, 47.25{\pm}4.65 % respectively. The serum chemical value were: GOT; 83.0{\pm}39.4 IU/L, GPT; 50.12{\pm}25.83 IU/L, BUN; 36.63{\pm}8.70 mg/dl. CPK ; 1,296{\pm}495 IU/L, ALP; 238{\pm}54 IU/L, glucose; 143{\pm}52 mg/dl, total protein; 6.95{\pm}0.61 g/dl, amylase ; 116.0{\pm}34.5 IU/L,$ respectively. These values will be clinically helpful to diagnose the disease of deer.

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A Studies on the Epidemiology of Caprine Anaplasmosis in Korea II. Therapy with Long Acting Terramycin (산양의 Anaplasmosis에 대한 역학적 조사 II . Terramycin을 이용한 치료시험)

  • 서석열;서이원;조선기;허철호;김동선;손구례;백병걸
    • Korean Journal of Veterinary Service
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    • v.17 no.1
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    • pp.54-60
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    • 1994
  • Anaplasmosis is a tick-borne disease mainly of cattle, sheep, and goats. Anaplasmosis in goat had been reported at last year by authors. The disease brought the economic losses in the goat farm in Chonbuk province. In order to treat the disease, a long-acting formulation terramycin injectable solution was used experimental animals which indigenous goats were sick with moderate anemia. We were devided into two groups was treated with single dosage (20mg /kg of body weight). one group was treated with single injection, the other group was treated with twice of the same dosage intramusculary injection. The results indicate that the use of long-acting terramycin would minimize clinical signs of anaplasmosis infection in goat. After treament the differrences of hematological appearences and parasitaemia were observed in the effect of terramycin treatment. obviously, increased value of RBC. HB and HCT, and parasitaemia by means of Giemsa staining and acrydine orange staining was observed decreased due to treatment.

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