• Title/Summary/Keyword: R170

Search Result 530, Processing Time 0.028 seconds

Studies on the Regional Cerebral Blood Flow in Delayed Carbon Monoxide sequelae using $^{99m}Tc-HMPAO$ (지연성 일산화탄소중독후유증 환자에서 $^{99m}Tc-HMPAO$를 이용한 국소 뇌혈류량의 SPECT소견)

  • Ahn, Jae-Hoon;Lee, Do-Yun;Kim, Jin-Soo;Suh, Jung-Ho;Kim, Dong-Ik;Lee, Myung-Sik;Chung, Tae-Sub;Park, Chan-H.
    • The Korean Journal of Nuclear Medicine
    • /
    • v.22 no.2
    • /
    • pp.163-170
    • /
    • 1988
  • 8 patients of delayed CO sequelae were evaluated using Brain CT and $^{99m}Tc-HMPAO$ SPECT. The results were as follows; 1) CT findings of delayed CO sequleae were bilateral low density lesion in globus pallidus (l pt.), diffuse low density in white matter with bilateral low density in white matter (l pt.), diffuse low density in white matter with bilateral low density in globus pallidus (l pt.), diffuse low density in white matter with cortical atrophy (l pt.), bilateral low density in globus pallidus and diffuse low density in white matter with cortical atrophy (l pt.) and normal in 3 pts. 2) $^{99m}Tc-HMPAO$ Brain SPECT findings of delayed CO sequelae were decreased regional cerebral blood flow (rCBF) in frontal (1 among 8 pts.), frontal and basal ganglia (3 among 8 pts.), and diffuse patch decreased rCBF pattern (4 among 8 pts.) 3) $^{99m}Tc-HMPAO$ Brain SPECT study was well correlated with neurologic symptoms and signs in delayed CO sequelae. Our results may suggest that reduced cerebral blood flow contributes to the development of delayed CO sequelae.

  • PDF

Evaluation of Visual Responses in Viewing a 3D Image (3D 영상 시청 시 시각반응의 평가)

  • Lee, Mu-Hyuk;Son, Jeong-Sik;Kim, Jaedo;Yu, Dong-Sik
    • Journal of Korean Ophthalmic Optics Society
    • /
    • v.17 no.2
    • /
    • pp.165-170
    • /
    • 2012
  • Purpose: The aim of this study was to measure and evaluate changes of visual responses in viewing a 2D and 3D (three-dimensional) image. Methods: The subjects were 44 college students aged 19 to 25 years with normal binocular vision. The visual responses measured were CA/C (convergence accommodation/convergence) ratio, convergence-induced PD(interpupillary distance), accommodative responses, perceived distance in viewing a 3D image. Results: Convergence and accommodative responses in viewing the 3D image were significantly larger (p<0.05) than in 2D. A moderate positive correction was found between CA/C ratio and accommodative response (r = 0.477, p = 0.001). It was indicated that smaller PD had larger depth perception. Convergence in viewing the 3D image was significantly larger (p<0.05) than that at cognitive distance. Conclusions: The visual fatigue may be more intense in larger CA/C ratio and smaller PD when viewing 3D images.

Effect of Process Aids on Rheological and Mechanical Properties of Styrene-Butadiene Rubber Compound (가공조제가 Styrene-Butadiene Rubber 배합고무의 유변특성 및 기계적 물성에 미치는 영향)

  • Kang, Yong-Gu;Jung, Hoon;Kim, Tae-Nyun;Kim, Wan-Doo;Nah, Chang-Woon
    • Elastomers and Composites
    • /
    • v.37 no.3
    • /
    • pp.170-176
    • /
    • 2002
  • Effects of type and loading level of process aids on the rheological and mechanical properties of styrene-butadiene rubber (SBR) compound were investigated. Five commercial grades of process aids composed of fatty acids and their various derivatives such as metal salts, esters, alcohols and amides were selected. The reduction in Mooney and shear viscosities was higher for metal salt-type process aids but lower for the process aids containing high molecular weight fatty acid alcohols and esters with increasing the loading of process aids. Tensile modulus generally decreased, while heat-build-up increased with increased process aids content. No considerable effect was observed for ulimate properties such as tensile strength and elongation at break.

Frequency and Type of Disputed rpoB Mutations in Mycobacterium tuberculosis Isolates from South Korea

  • Jo, Kyung-Wook;Lee, Soyeon;Kang, Mi Ran;Sung, Heungsup;Kim, Mi-Na;Shim, Tae Sun
    • Tuberculosis and Respiratory Diseases
    • /
    • v.80 no.3
    • /
    • pp.270-276
    • /
    • 2017
  • Background: A disputed rpoB mutation is a specific type of rpoB mutation that can cause low-level resistances to rifampin (RIF). Here, we aimed to assess the frequency and types of disputed rpoB mutations in Mycobacterium tuberculosis isolates from South Korea. Methods: Between August 2009 and December 2015, 130 patients exhibited RIF resistance on the MTBDRplus assay at Asan Medical Center. Among these cases, we identified the strains with disputed rpoB mutation by rpoB sequencing analysis, as well as among the M. tuberculosis strains from the International Tuberculosis Research Center (ITRC). Results: Among our cases, disputed rpoB mutations led to RIF resistance in at least 6.9% (9/130) of the strains that also exhibited RIF resistance on the MTBDRplus assay. Moreover, at the ITRC, sequencing of the rpoB gene of 170 strains with the rpoB mutation indicated that 23 strains (13.5%) had the disputed mutations. By combining the findings from the 32 strains from our center and the ITRC, we identified the type of disputed rpoB mutation as follows: CTG511CCG (L511P, n=8), GAC516TAC (D516Y, n=8), CTG533CCG (L533P, n=8), CAC526CTC (H526L, n=4), CAC526AAC (H526N, n=3), and ATG515GTG (M515V, n=1). Conclusion: Disputed rpoB mutations do not seem to be rare among the strains exhibiting RIF resistance in South Korea.

The Effects of Carbon Dioxide as Additives on Soot Formatio in Jet Diffusion Flames (제트확산화염에서 이산화탄소의 첨가가 매연생성에 미치는 영향)

  • Ji, Jung-Hoon;Lee, Eui-Ju
    • Fire Science and Engineering
    • /
    • v.24 no.6
    • /
    • pp.170-175
    • /
    • 2010
  • The effect of carbon dioxide addition on soot formation was investigated in jet diffusion flames in coflow. Flame temperature were measured with R-type thermocouple and the boundary temperature between blue and yellow flame was confirmed. Light-extinction method was introduced for the relative soot density (1-I/$I_0$) in the in-flame region. He-Ne laser with wave length at 632.8 nm was used for the light source, and the signal attenuated by absorption and scattering was detected directly. Oxidizer velocity effect on soot formation was studied to know that the thermal influence for soot formation. The results showed that the temperature of both blue and yellow flame were decreased according to the dilution of carbon dioxide but boundary temperature was nearly constant. The relative soot density was lower when carbon dioxide was added in oxidizer stream and oxidizer velocity increased. These were caused by the reduction of flame temperature and shorter residence time for soot growth. Also carbon dioxide addition enhanced the instability of jet flames like flickering, so the flame length was a little longer than pure ethylene/air flame.

Associations of CYP1A1, GSTM1 and GSTT1 Polymorphisms with Lung Cancer Susceptibility in a Northern Indian Population

  • Shukla, R.K.;Tilak, A.R.;Kumar, C.;Kant, S.;Kumar, A.;Mittal, B.;Bhattacharya, S.
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.5
    • /
    • pp.3345-3349
    • /
    • 2013
  • Background: Susceptibility to lung cancer has been shown to be modulated by inheritance of polymorphic genes encoding cytochrome P450 1A1 (CYP1A1) and glutathione S transferases (GSTM1 and GSTT1), which are involved in the bioactivation and detoxification of environmental toxins. This might be a factor in the variation in lung cancer incidence with ethnicity. Materials and Methods: We conducted a case-control study of 218 northern Indian lung cancer patients along with 238 healthy controls, to assess any association between CYP1A1, GSTM1 and GSTT1 polymorphisms, either separately or in combination, with the likelihood of development of Lung cancer in our population. Results: We observed a significant difference in the GSTT1 null deletion frequency in this population when compared with other populations (OR=1.87, 95%CI: 1.25-2.80-0.73, P=0.002). However, GSTM1 null genotype was found associated with lung cancer in the non-smoking subgroup. (P=0.170). Conclusions: Our study showed the GSTT1 null polymorphism to be associated with smoking-induced lung cancer and the GSTM1 null polymorphism to have a link with non-smoking related lung cancer.

Mapping, Tissue Distribution and Polymorphism Study of the Porcine SOCS2 and SOCS3 Genes

  • Li, X.Y.;Liu, B.;Fan, B.;Yu, M.;Zhu, M.J.;Xiong, T.A.;Li, K.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.19 no.2
    • /
    • pp.165-170
    • /
    • 2006
  • Using the somatic cell hybrid panel (SCHP) and radiation hybrid (IMpRH) panel, porcine SOCS2 gene was mapped at SSC5 (1/2) q21-q24 and closely linked with SW1383 marker (47 cR in distance), while SOCS3 gene was assigned to SSC12p11-(2/3p13) and closely linked with SW2490 (43 cR). The reverse transcriptase-polymerase chain reaction (RT-PCR) was performed to detect the expression of these two genes in the different tissues and the results showed that both SOCS2 and SOCS3 genes were widely expressed in tissues investigated (heart, liver, spleen, lung, kidney skeletal muscle, fat and brain), although some tissues showed lower gene expression. Moreover, SOCS2 and SOCS3 genes had different expression levels at different stages, in different tissues and in different breeds. A G/A substitution, which can be recognized by restriction enzyme of Cfr421, was observed in 5' untranslated region (5'-UTR) of SOCS2 gene. The allele frequencies was investigated by PCR-restriction fragment length polymorphism (PCR-RFLP) method and it showed that the allele frequency among Dahuabai, Erhualian, Yushan, Qingping, Large white and Landrace tested were different. Association analysis in a cross experimental populations revealed no significant association between the SOCS2 gene polymorphism and the economic traits investigated. The full-length coding regions (CDs) of porcine SOCS3 gene was obtained by RT-PCR.

Dielectric and Piezoelectric Properties of $MnO_2$-Added 0.4P$(Ni_{1/3}Nb_{2/3})O_3-xPbTiO_3-yPbZrO_3$ Ceramics with Variation of PZ/PT Ratio ($MnO_2$ 가 첨가된 0.4P$(Ni_{1/3}Nb_{2/3})O_3-xPbTiO_3-yPbZrO_3$ 세라믹스에서의 PZ/PT비 변화에 따른 유전 및 압전 특성)

  • Paik, Jong-Hoo;Kim, Chang-Il;Lim, Eun-Kyeong;Lee, Mi-Jae;Ji, Mi-Jeong;Choi, Byung-Hyun;Kim, Sei-Ki
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
    • /
    • 2005.11a
    • /
    • pp.169-170
    • /
    • 2005
  • 본 연구에서는 초음파 센서에 응용 가능한 $0.4Pb(Ni_{1/3}Nb_{2/3})O_3-0.6Pb(Zr_xTi_{1-x})O_3+0.5Wt%$ $MnO_2$ 세라믹스에 Zr/(Ti+Zr)비를 0.37에서 0.41로 변화시킨 조성을 1175 $\sim$ 1200$^{\circ}C$ 온도에서 소결하여 이의 결정구조 및 미세조직을 분석하였고, 압전, 유전 특성을 고찰하였다. 본조성에서 x=0.385 조성에서 최대 유전상수 값 3490 이 나타났으며, 그 이상의 첨가에서는 감소하였다. 상경계 영역인 x=0.385 조성에서 $\varepsilon$r, $K_p$, $d_{33}$ 값이 최대값을 나타내었다. $0.4Pb(Ni_{1/3}Nb_{2/3})O_3-0.6Pb(Zr_xTi_{1-x})O_3+0.5Wt%$ $MnO_2$, 세라믹스에서는 kp 와 $d_{33}$ 는 Zr/(Ti+Zr)비 0.385조성까지 증가하였다가 그 이상 조성에서 감소하였다. $1175^{\circ}C$에서 2시간 소결한 x=0.385조성에서 $\varepsilon$r=3490, kp=0.71, Qm=476의 우수한 압전 특성을 나타내었다.

  • PDF

Studies on the Interspecific and Intergeneric Hybridization in Herbage Graasses III. Isolation and culture of protoplasts from cultured cells of Italian ryegass (Lolium multiflorum Lam.) (화본과 목초의 종.속간 잡종에 관한 연구 III. 이탈리안 라이그라스의 배양세포로부터 원형질체의 분리와 배양)

  • 이영현;박병훈
    • Journal of The Korean Society of Grassland and Forage Science
    • /
    • v.13 no.3
    • /
    • pp.170-176
    • /
    • 1993
  • The yield, viability and continuous culture of isolated Italian ryegrass protoplasts were investigated. The effects of cold treatment (4^{\circ}C.$) for 7 days and basic LS medium supplemented with 5mg/l $AgNO_3$ showed effectively on embryogenic callus induction and regeneration responses of immature and mature embryos or young inflorescences subcultured every 4 weeks on basic medium. The optimum combinations of growth regulator on the regeneration responses was 0.2mg/l BAP and 2mg/l 2, 4-D. Calli induced inflorescences were suspended in its liquid medium for 5 days before enzyme treatment. Maximum protoplast yield and viability were obtained after digestion in enzyme solution contained 4% cellulase R10. 2% macerozyme and 2% pectinase in 0.6M mannitol. Cell division and microcalli development were observed in isolated protoplasts cultured in agarose culture of KM8P medium.

  • PDF

Detection of Gamma-Irradiated Wheat Flour and Glutinous Rice Flour by Measuring Free Radical (Free radical의 측정을 통한 감마선 조사된 밀가루와 찹쌀가루의 검지)

  • Lee, Eun-Jeong;Yang, Jae-Seung
    • Korean Journal of Food Science and Technology
    • /
    • v.34 no.2
    • /
    • pp.170-173
    • /
    • 2002
  • Electron spin resonance (ESR) spectroscopy was used to detect free radicals in irradiated wheat flour and glutinous rice flour. They were irradiated with doses of 0, 0.1, 0.5, 1 and 2 kGy at room temperature using a Co-60 irradiator. Free radicals detected for irradiated wheat flour and glutinous rice flour were higher than those of unirradiated ones. Since concentration of free radicals linearly increased with applied doses $(0.1{\sim}2\;kGy)$, highly positive correlation coefficients $(R^2=0.9995{\sim}0.9998)$ were obtained between irradiation doses and free radical concentrations right after irradiation. Although concentration of free radicals slowly decreased with storage time, the characteristic ESR signals of free radical in irradiated samples were observed even after 4 weeks of storage at room temperature.