• Title/Summary/Keyword: R-l34a

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A Study on Shoulder Joint ROM of the Elderly (노인의 견관절 가동범위에 관한 연구)

  • Um, Ki-Mai;Yang, Yoon-Kwon
    • Journal of Korean Physical Therapy Science
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    • v.8 no.2
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    • pp.997-1003
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    • 2001
  • The purpose of this study is to know the average of pint range of motion and difference according to the aging for the elderly, This study consisted of elder male(n=75) and elder female(n=l09), The result of assessment and analysis in shoulder pint range of motion are as follows: 1) The average shoulder flexion pint range of motion in 60-69(from sixty to sixty-nine)years old are 163.04(Left-Male), 162.91(Right-Male), 158.74 (Left-Female), 158.74 (Right-Female). 70-79years old are 149.40(L-M), 152.38(R-M), 153,37(L-F), 153.37(R-F). 80-89 years old are 149.57(L-M), 147.93(R-M), 151.17(L-F), 150.33(R-F). There was no significant difference among group, 2) The average shoulder extension pint range of motion in 60-69years old are 48.15(L-M), 47.20(R-M), 45.16(L-F), 44.23(R-F), 70-79years old are 37.l1(L-M), 38.70(R-M), 35.17(L-F), 36.71(R-F), 80-89 years old are 34.46(L-M). 36.71(R-M), 33.90(L-F), 33.09(R-F). There was significant difference among group(p<.05). 3) The average shoulder abduction pint range of motion in 60-69years old are 164.22(L-M), 165.96(R-M), 159.34(L-F), 159.97(R-F), 70-79years old are 152.27(L-M), 155.05(R-M), 152.32(L-F), 53.66(R-F), 80-89 years old are 152.17(L-M), 153.76(R-M), 147.53(L-F), 147.37(R-F). There was significant difference in right shoulder abduction among group(p<05). 4) The average shoulder internal rotation pint range of motion in 60-69years old are 63.52(L-M), 65.70(R-M), 64.16(L-F), 64.61(R-F), 70-79years old are 64.50(L-M), 65.81(R-M) 61.10(L-F), 61.83(R-F). 80-89 years old are 61.60(L-M), 61.66(R-M), 57.53(L-F), 57.53(R-F). There was no significant difference among group. 5) The average shoulder external rotation pint range of motion in 60-69years old are 50.87(L-M), 50.22(R-M), 51.03(L-F), 50.42(R-F), 70-79years old are 50.91(L-M), 50.20(R-M) 48.37(L-F), 50.20(R-F). 80-89 years old are 46.83(L-M), 47.93(R-M), 43.43(L-F), 43.72(R-F).There was significant difference in left shoulder external rotation among group(p<.05).

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Gadolinium Complex of 1,4,7,10-Tetraazacyclododecane-1,4,7-trisacetic acid (DO3A) Conjugate of [(p-aniline benzothiazole)methyl]pyridine as a Tumor-Targeting MRI Contrast Agent

  • Nam, Ki Soo;Jung, Ki-Hye;Chang, Yongmin;Kim, Tae-Jeong
    • Bulletin of the Korean Chemical Society
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    • v.34 no.12
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    • pp.3654-3658
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    • 2013
  • The synthesis of a DO3A conjugate of [(p-aniline benzothiazole)methyl]pyridine ($L^2H_3$) and its gadolinium complex of the type [$Gd(L^2)(H_2O)$] ($GdL^2$) is described. The $R_1$ relaxivity ($=4.50mM^{-1}sec^{-1}$) and kinetic inertness of $GdL^2$ compares well with those of structurally analogous Dotarem$^{(R)}$ ($R_1=3.70mM^{-1}sec^{-1}$), a typical extracellular (ECF) MRI contrast agent (CA). Yet, by comparison with Dotarem$^{(R)}$, $GdL^2$ exhibits non-covalent interactions with human serum albumin (HSA) as evidenced by the ${\varepsilon}^*$ titration curve along with in vivo MR signal enhancement in both aorta and heart. Liver-specific nature of $GdL^2$ is also observed as excretion is made through gallbladder. Most notably, $GdL^2$ further demonstrates specificity toward the MDA-MB-231 breast cancer.

In vitro and in vivo inhibition of Helicobacter pylori by Lactobacilllus paracasei HP7

  • Hong, Seong-Soo;Lee, Hyun-A;Kim, Joo Yun;Jeong, Ji-Woong;Shim, Jae-Jung;Lee, Jung Lyoul;Sim, Jae-Hun;Chung, Yungho;Kim, Okjin
    • Laboraroty Animal Research
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    • v.34 no.4
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    • pp.216-222
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    • 2018
  • The efficacy of standard therapeutic strategies for Helicobacter pylori (H. pylori) infection is decreasing over time due to the emergence of drug-resistant strains. As an alternative, the present study investigated the capacity of Lactobacilllus paracasei (L. paracasei) HP7, isolated from kimchi, to inhibit H. pylori growth. The effects of L. paracasei HP7 on H. pylori adhesion and H. pylori-induced inflammation were examined in AGS human gastric adenocarcinoma epithelial cells and a mouse model of H. pylori SS1 infection. L. paracasei HP7 reduced H. pylori adhesion to AGS cells and suppressed the inflammatory response in infected cells by downregulating interleukin-8. H. pylori colonization in the stomach of C57BL/6 mice was demonstrated by rapid urease test, and results showed significant decrease in mice post-treated with L. paracasei HP7. Additionally, L. paracasei HP7 decreased gastric inflammation and epithelial lesions in the stomach of H. pylori-infected mice. These results demonstrate that L. paracasei HP7 treatment can inhibit H. pylori growth and is thus a promising treatment for patients with gastric symptoms such as gastritis that are caused by H. pylori infection.

Totally umbilic lorentzian surfaces embedded in $L^n$

  • Hong, Seong-Kowan
    • Bulletin of the Korean Mathematical Society
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    • v.34 no.1
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    • pp.9-17
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    • 1997
  • Define $\bar{g}{\upsilon, \omega) = -\upsilon_1\omega_1 + \cdots + \upsilon_n\omega_n$ for $\upsilon, \omega in R^n$. $R^n$ together with this metric is called the Lorentzian n-space, denoted by $L^n$, and $R^n$ together with the Euclidean metric is called the Euclidean n-space, denoted by $E^n$. A Lorentzian surface in $L^n$ means an orientable connected 2-dimensional Lorentzian submanifold of $L^n$ equipped with the induced Lorentzian metrix g from $\bar{g}$.

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Toxicity Assessment of Heavy Metals (As, Cr and Pb) Using the Rates of Survival and Population Growth in Marine Rotifer, Brachionus plicatilis (해산로티퍼 (Brachionus plicatilis)의 생존 및 개체군 성장률을 이용한 중금속 (As, Cr, Pb) 독성평가)

  • Lee, Ju-Wook;Ryu, Hyang-Mi;Heo, Seung;Hwang, Un-Ki
    • Korean Journal of Environmental Biology
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    • v.34 no.3
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    • pp.193-200
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    • 2016
  • Toxicity assessment of heavy metals (As, Cr and Pb) has been investigated by using the rate of survival and population growth(r) of marine rotifer, Brachionus plicatilis. The survival rate was determined after 24 hours of exposure to As, Cr and Pb. As and Cr reduced survival rate in dose-dependent manner and a significant reduction were occurred at concentration of greater than 30 and $150mg\;L^{-1}$, but Pb had no effect on survival rate. The r was determined after 72 hours of exposure to As, Cr and Pb. As, Cr and Pb reduced r in dose-dependent manner and a significant reduction were occurred at concentration of greater than 5, 25 and $50mg\;L^{-1}$. The toxicity of heavy metals were ranked As>Cr>Pb, with $EC_{50}$ values of 12.98, 82.34 and $110.14mg\;L^{-1}$, respectively. The no-observed-effect-concentration (NOEC) of r in As, Cr and Pb exposure were 1, 12.5 and $50mg\;L^{-1}$, respectively. The lowest-observed-effect-concentration (LOEC) of r in As, Cr and Pb exposure were 5, 25, and $50mg\;L^{-1}$, respectively. From the results, the concentration of As, Cr and Pb (greater than 5, 25 and $50mg\;L^{-1}$, respectively) have toxic effect on the r of B. plicatilis in natural ecosystems. These results (including NOEC and $EC_{50}$) might be useful for the mixing toxicity assessment and toxic guide line of heavy metals in marine ecosystems.

Periodontal Disease and Health Related Quality of Life (HRQoL) in Pregnant Women (임신여성의 치주질환과 건강 관련 삶의 질)

  • Park, Hae-jin;Lee, Haejung;Cho, Soohyun
    • Women's Health Nursing
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    • v.22 no.4
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    • pp.191-201
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    • 2016
  • Purpose: The purpose of this study was to identify relationships of periodontal disease and health related quality of life (HRQoL) in pregnant women. Methods: The participants in this study were 129 pregnant women. Data were collected using questionnaires of characteristics of the participants and subjective perception of periodontal disease and a dentist's assessment of periodontal disease. Data were analyzed using descriptive statistics, correlation, and hierarchical multiple regression. Results: The physical QoL showed significant negative correlation with subjective perception of periodontal disease (r=-.21, p=.013). Mental QoL had significant negative correlations with subjective perception of periodontal disease (r=-.32, p<.001) and objective periodontal disease (r=-.34, p<.001). Hierarchical multiple regression analyses revealed that pregnant women who had a history of abortion and had higher subjective perception of periodontal disease tended to report lower levels of physical QoL. Pregnant women whose age are between 30-34 years and higher subjective perception and objective periodontal disease tended to report lower mental QoL. Conclusion: To improve HRQoL of pregnant women, nurses should pay attention on the status of periodontal disease. Careful assessment of oral healthy behaviors and proper intervention for oral health of pregnant women are needed to enhance HRQoL of pregnant women.

WEAKTYPE $L^1(R^n)$-ESTIMATE FOR CRETAIN MAXIMAL OPERATORS

  • Kim, Yong-Cheol
    • Journal of the Korean Mathematical Society
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    • v.34 no.4
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    • pp.1029-1036
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    • 1997
  • Let ${A_t)}_{t>0}$ be a dilation group given by $A_t = exp(-P log t)$, where P is a real $n \times n$ matrix whose eigenvalues has strictly positive real part. Let $\nu$ be the trace of P and $P^*$ denote the adjoint of pp. Suppose that $K$ is a function defined on $R^n$ such that $$\mid$K(x)$\mid$ \leq k($\mid$x$\mid$_Q)$ for a bounded and decreasing function $k(t) on R_+$ satisfying $k \diamond $\mid$\cdot$\mid$_Q \in \cup_{\varepsilon >0}L^1((1 + $\mid$x$\mid$)^\varepsilon dx)$ where $Q = \int_{0}^{\infty} exp(-tP^*) exp(-tP)$ dt and the norm $$\mid$\cdot$\mid$_Q$ stands for $$\mid$x$\mid$_Q = \sqrt{}, x \in R^n$. For $f \in L^1(R^n)$, define $mf(x) = sup_{t>0}$\mid$K_t * f(x)$\mid$$ where $K_t(X) = t^{-\nu}K(A_{1/t}^* x)$. Then we show that $m$ is a bounded operator of $L^1(R^n) into L^{1, \infty}(R^n)$.

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Numerical Study on Tip Clearance Effect on Performance Characteristics of a Centrifugal Compressor for a R134a Turbo-Chiller (R134a 터보냉동기용 원심압축기의 익단간극이 성능특성에 미치는 영향에 관한 수치해석적 연구)

  • Lee, Kyoung-Yong;Choi, Young-Seok;Park, Woon-Jean
    • 유체기계공업학회:학술대회논문집
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    • 2003.12a
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    • pp.451-456
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    • 2003
  • In this study, the overall performance and the effect of the tip leakage flow of the centrifugal compressor with the refrigerant HFC-l34a were numerically studied using CFX-TASCflow. To study the effect of a tip leakage flow, the numerical study of the overall performance of HFC-l34a centrifugal compressor with a cascade diffuser was preceded and compared with experimental result. Six different tip clearances were used to consider the influence of a tip clearance on performance. The tip leakage flow was illustrated for qualitative discussion. The results obtained in this study can be applied to the determination of the cold clearance.

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Numerical Study on Tip Clearance Effect on Performance Characteristics of a Centrifugal Compressor for a R134a Turbo-Chiller (R134a 터보냉동기용 원심압축기의 익단간극이 성능특성에 미치는 영향에 관한 수치해석적 연구)

  • Lee, Kyoung-Yong;Choi, Young-Seok;Park, Woon-Jean
    • The KSFM Journal of Fluid Machinery
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    • v.7 no.6 s.27
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    • pp.38-44
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    • 2004
  • In this study, the overall performance and the effect of the tip leakage flow of the centrifugal compressor with a refrigerant HFC-l34a were numerically studied using CFX-TASCflow. To study the effect of the tip leakage flow, the numerical study of the overall performance of HFC-l34a centrifugal compressor with a cascade diffuser was preceded and compared with the experimental result. Six different tip clearances were used to consider the influence of the tip clearance on the performance. The tip leakage flow was illustrated for qualitative discussion. The results obtained in this study can be applied to the determination of the cold clearance.

Forced Convective Boiling of Pure Refrigerants in a Bundle of Enhanced Tubes (전열촉진관군의 순수냉매 강제대류비등)

  • Kim, Nae-Hyeon;Jeong, Ho-Jong;Jo, Jin-Pyo;Choe, Guk-Gwang
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.25 no.12
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    • pp.1831-1843
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    • 2001
  • In this study, convective boiling tests were conducted for enhanced tube bundles. The surface geometry consists of pores and connecting gaps. Tubes with three different pore sizes (d$_{p}$ = 0.20, 0.23 and 0.27 mm) were tested using R-123 and R-l34a for the following range: 8 kg/m$^2$s G 26 kg/m$^2$s, 10 kW/m$^2$ q0 40 kW/m$^2$and 0.1 $\chi$ 0.9. The convective boiling heat transfer coefficients were strongly dependent on heat flux with negligible dependency on mass flux or quality. For the present enhanced geometry (pores and gaps), the convective effect was apparent. The gaps of the present tubes may have served routes for the passage of two-phase mixtures, and enhanced the boiling heat transfer. The convective effect was more pronounced at a higher saturation temperature. More bubbles will be generated at a higher saturation temperature, which will lead to enhanced convective contribution. The pore size where the maximum heat transfer coefficient was obtained was larger for R-l34a (d$_{p}$ = 0.27 mm) compared with that for R-123 (d$_{p}$ = 0.23 mm). This trend was consistent with the previous pool boiling results. For the enhanced tube bundles, the convective effect was more pronounced for R-134a than for R-123. This trend was reversed for the smooth tube bundle. Possible reasoning is provided based on the bubble behavior on the tube wall. Both the modified Chen and the asymptotic model predicted the present data reasonably well. The RMSEs were 14.3% for the modified Chen model and 12.7% for the asymptotic model.model.