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Effects of Lower-Bound Resistances on Resistance Factors Calibration for Drilled Shafts (하한지지력이 현장타설말뚝의 저항계수에 미치는 영향)

  • Kim, Seok-Jung;Park, Jae-Hyun;Kim, Myoung-Mo
    • Journal of the Korean Geotechnical Society
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    • v.30 no.11
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    • pp.51-60
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    • 2014
  • Load and Resistance Factor Design (LRFD) is one of the limit state design methods, and has been used worldwide, especially in North America. Also, the study for LRFD has been actively conducted in Korea. However, the data for LRFD in Korea were not sufficient, so resistance factors suggested by AASTTO have been used for the design in Korea. But the resistance factors suggested by AASHTO represent the characteristics of bedrocks defined in the US, therefore, it is necessary to determine the resistance factors for designs in Korea, which can reflect the characteristics of bedrocks in Korea. Also, the calculated probabilities of failure from conventional reliability analyses which commonly use log-normal distribution are not realistic because of the lower tail that can be extended to zero. Therefore, it is necessary to calibrate the resistance factors considering the lower-bound resistance. Thus, this study calculates the resistance factors using thirteen sets of drilled shaft load test results, and then calibrates the resistance factors considering the lower-bound resistance corresponding to a target reliability index of 3.0. As a result, resistance factors from conventional reliability analyses were determined in the range of 0.13-0.32 for the shaft resistance, and 0.19-0.29 for the base resistance, respectively. Also, the lower bounds of resistance were determined based on the Hoek-Brown failure criteria (2002) and GSI downgrading. Considering the lower-bound resistances, resistance factors increased by 0~8% for the shaft, and 0~13% for the base, respectively.

Correlation between Measured Resting Energy Expenditure and Predicted Basal Energy Expenditure in Female College Students (여대생을 대상으로 한 실측 휴식대사량과 예측 기초대사량의 상관관계에 관한 연구)

  • Chang, Un-Jae;Lee, Kyeong-Ryeong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.2
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    • pp.196-201
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    • 2005
  • The aim of this study was to confirm the validity of predictive equations for the calculation of basal energy expenditure (BEE). One hundred twenty female college students were participated in this study. The resting energy expenditure (REE) was measured by indirect calorimetry for 30 minutes following an 12 hour overnight fasting. Among the available equations for predict BEE, Harris-Benedict, WHO/FAO/UNU and Cunningham methods were selected. Body composition was estimated by bioelectrical impedance analysis (BIA) for the equation of predicted BEE. The mean of measured REE was 1257.2$\pm$147.9 kcal/day, while the predicted value by Harris-Benedict, WHO/FAO/UNU and Cunningham were 1373.3$\pm$45.4 kcal/day, 1290.0$\pm$61.7 kcal/day and 1187.6$\pm$49.2 kcal/day, respectively. The Cunningham equation was more closed to measured values than Harris-Benedict and WHO/FAO/UNU equation by the correlation coefficient. Comparing Pearson's correlation coefficients, fat-free mass (FFM), body surface area (BSA) and body weight were higher than others such as height, body mass index (BMI), fat and fat%. The FFM's correlation coefficient was the highest as 0.74. Thus, the conclusion of this study suggested that the main determinant of BEE was FFM, and we derived a prediction equation as follows: BEE=-569.86+48.27 (FFM).

Physico-Chemical Changes in Pork Bellies with Different Cooking Methods (조리방법에 따른 삼겹살의 물리화학적 특성 변화)

  • Yang, Jong-Beom;Ko, Myung-Soo;Kim, Kwang-Soo
    • Food Science and Preservation
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    • v.16 no.1
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    • pp.87-93
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    • 2009
  • This study was carried out to suggest an effective cooking method for pork bellies to decrease intake of animal fat. The physico-chemical characteristics of pork bellies cooked by different methods (boiling, steaming, baking and frying) were investigated. The moisture contents of cooked meats decreased but crude lipid contents increased. The cooking losses, moisture drain rates, and lipid drain rates were high after frying and boiling. The pH values increased markedly with boiling and both the acid value and the refraction index of the fat significantly increased with frying. The hardness, gumminess, and chewiness of the meat increased considerably with boiling, but decreased notably after frying. The springiness decreased very much with boiling and cohesiveness greatly increased with steaming. The CIE $L^*$ (lightness) value increased notably with steaming but decreased markedly with frying. The CIE $a^*$ (redness) value decreased markedly with all cooking methods, especially boiling, and the CIE $b^*$ (yellowness) value decreased with both boiling and steaming but increased with both baking and frying. The fatty acids of fat from the raw pork bellies were primarily oleic acid (42.4%), palmitic acid (23.9%), and linoleic acid (16.1%). The ratio of total monounsaturated fatty acids to total saturated fatty acids was 1.190 and the ratio of total polyunsaturated fatty acids to total saturated fatty acids was 0.446. In addition, the composition of fatty acids was not significantly changed with any cooking method except frying. Therefore, boiling is the effective cooking method for pork bellies to decrease intake of animal fats.

Analysis on Herbaceous Communities and Flora around Abeliophyllum distichum Habitats (미선나무 자생지 주변의 초본군락과 식물상 분석)

  • You Ju-Han;Lee Cheol-Hee
    • Korean Journal of Plant Resources
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    • v.18 no.2
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    • pp.315-324
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    • 2005
  • The study was carried out to offer the raw data on counterplan of restoration and conservation by systematical and objective analyzing the flora and herbaceous communities around Abeliophyllum distichum habitats. In the results of flora survey, as the site that the most taxa were showed was Yulji-ri, Geosan-gun III, there was surveyed as 114 ones; 48 families, 91 genera, 99 species and 15 varieties, and as Younjeong-ri, Jincheon-gun V was showed the fewest ones, there was appeared 54 ones; 28 families, 49 genera, 47 species and 7 varieties. The dominant species of herbaceous communities were verified Humulus japonicus${\cdot}$Artemisia princeps var. orientalis(Chujeom-ri, Goesan-gun I), Oplismenus undulatifolius(Songdeok-ri, Goesan-gun II and Maechon-ri, Yeongdong-eup IV), Carex siderosticta${\cdot}$Pueraria thunbergiana${\cdot}$Artemisia princeps var. orientalis(Yulji-ri, Geosan-gun III), Streptolirion cordifolium(Younjeong-ri, Jincheon-Eun V) and Sasa borealis(Junggye-ri, Buan-gun IV). In correlation analysis, Artemisia princeps var. orientalis${\cdot}$Carex siderosticta, Sasa borealis${\cdot}$Festuca ovina, Sasa borealis${\cdot}$Smilax china and Festuca ovina${\cdot}$Smilax china were showed the highest relativity. In similarity index analysis, as the site that was showed highest value was Yulji-ri, Geosan-gun III and Maechon-ri, Yeongdong-eup IV, there was turned up about some $27.27\%$. In the results of regression analysis between environmental factors and number of species, R-square of altitude and number of species was some $70.0\%$.

Antitumor Activity of 7-[2-(N-Isopropylamino)ethyl]-(20s)-camptothecin, CKD602, as a Potent DNA Topoisomerase I Inhibitor

  • Lee, Jun-Hee;Lee, Ju-Mong;Kim, Joon-Kyum;Ahn, Soon-Kil;Lee, Sang-Joon;Kim, Mie-Young;Jew, Sang-Sup;Park, Jae-Gab;Hong, Chung-Il
    • Archives of Pharmacal Research
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    • v.21 no.5
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    • pp.581-590
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    • 1998
  • We developed a novel water-soluble camptothecin analobue, CKD602, and evaluated the inhibition of topoisomerase I and the antitumor activities against mammalian tumor cells and human tumor xenografts. CKD602 was a nanomolar inhibitor of the topoisomerase I enzyme in the cleavable complex assay. CKD602 was found to be 3 times and slightly more potent than topotecan and camptothecin as inhibitors of topoisomerase, respecitively. In tumor cell cytotoxicity, CKD602 was more potent than topotecan in 14 out of 26 human cancer cell lines tested, while it was comparable to camptothecin. CKD602 was tested for the in vivo antitumor activity against the human tumor xenograft models. CKD602 was able to imduce regression of established HT-29, WIDR and CX-1 colon tumors, LX-1 lung tumor, MX-1 breast tumor and SKOV-3 ovarian tumor as much as 80, 94, 76, 67, 87% and 88%, respectively, with comparable body weight changes to those of topotecan. Also the therapeutic margin (R/Emax: maximum tolerance dose/$ED-{58}$) of CKD602 was significantly higher than that of topotecan by 4 times. Efficacy was determined at the maximal tolerated dose levels using schedule dependent i.p. administration in mice bearing L1210 leukemia. On a Q4dx4 (every 4 day for 4 doses) schedule, the maximum tolerated dose (MTD) was 25 mg/kg per administration, which caused great weight loss and lethality in <5% tumor bearing mouse. this schedule brought significant increase in life span (ILS), 212%, with 33% of long-term survivals. The ex vivo antitumor activity of CKD602 was compared with that of topotecan and the mean antitumor index (ATI) values recorded for CKD602 were significantly higher than that noted for topotecan. From these results, CKD602 warrants further clinical investigations as a potent inhibitor of topoisomerase I.

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Single-crystal Structure of Fully Dehydrated and Largely NH4+-exchanged Zeolite Y (FAU, Si/Al = 1.70), │(NH4)60Na11│[Si121Al71O384]-FAU

  • Seo, Sung-Man;Kim, Ghyung-Hwa;Kim, Young-Hun;Wang, Lian-Zhou;Lu, Gao-Qing;Lim, Woo-Taik
    • Bulletin of the Korean Chemical Society
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    • v.30 no.3
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    • pp.543-550
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    • 2009
  • The single-crystal structure of largely ammonium-exchanged zeolite Y dehydrated at room temperature (293 K) and 1 ${\times}\;10^{-6}$ Torr. has been determined using synchrotron X-radiation in the cubic space group $Fd\overline{3}m\;(a=24.9639(2)\AA)$ at 294 K. The structure was refined to the final error index $R_1$ = 0.0429 with 926 reflections where $F_o>4\sigma(F_o)$; the composition (best integers) was identified as |$(NH_4)_{60}Na_{11}$|[$Si_{121}Al_{71}O_{384}$]-FAU. The 11 $Na^{+}$ ions per unit cell were found at three different crystallographic sites and 60 ${NH_4}^{+}$ ions were distributed over three sites. The 3 $Na^{+}$ ions were located at site I, the center of the hexagonal prism ($Na-O\;=\;2.842(5)\;\AA\;and\;O-Na-O\;=\;85.98(12)^{\circ}$). The 4 $Na^{+}$ and 22 ${NH_4}^{+}$ ions were found at site I' in the sodalite cavity opposite the double 6-rings, respectively ($Na-O\;=\;2.53(13)\;\AA,\;O-Na-O\;=\;99.9(7)^{\circ},\;N-O\;=\;2.762(11)\;\AA,\;and\;O-N-O =\;89.1(5)^{\circ}$). About 4 $Na^{+}$ ions occupied site II ($(Na-O\;=\;2.40(4)\;\AA\;and\;O-Na-O\;=\;108.9(3)^{\circ}$) and 29 ${NH_4}^{+}$ ions occupy site II ($N-O\;=\;2.824(9)\;\AA\;and\;O-N-O\;=\;87.3(3)^{\circ}$) opposite to the single 6-rings in the supercage. The remaining 9 ${NH_4}^{+}$ ions were distributed over site III' ($N-O\;=\;2.55(3),\;2.725(13)\;\AA\;and\;O-N-O\;=\;94.1(13),\;62.16(15),\;155.7(14)^{\circ}$).

Design and deposition of two-layer antireflection and antistatic coatings using a TiN thin film (TiN 박막을 이용한 2층 무반사 코팅의 설계 및 층착)

  • 황보창권
    • Korean Journal of Optics and Photonics
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    • v.11 no.5
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    • pp.323-329
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    • 2000
  • In this study we have calculated an ideal complex refractive index of a TiN trim used in a layer of anl1reilecnon (I\R) coatmg, [air$ISiO_2ITiNIglass$] in the visible. Also we simulated the rellectance of lwo-layer AR coating by varying the thicknesses of TiN and $SiO_2$ layers, respecl1vely. The simolation results show that we can controllhe lowest reflectance and AR band of tile AR coating. The TIN fihns were fabricated by a RF magnetron sputtering apparalus. The chemical, structural and electrical properties of TiN fih11S were inveshgated by the Rutherford backscattering spech'oscopy (RBS), atomic force microscope (AFM) and 4-point probe. The optical properlies were inve,tigated by the spectrophotometer and vanable angle spectroscopic ellipsometer (VASE). The smface roughness of TiN flhns \vas $9~10\AA$. TIle resistivity of TiN films was TEX>$360~730\mu$\Omega $ cm. The ,toichlOllletry of TiN film was 1'1: O:N = I: 0.65 :0.95 and ilic oxygen wa~ found on ilie smface. With these experimental and simu]al1on resulLs, we deposited duo: two-layer AR coating, [air$ISiO_2ITiNIglass$] and the refleClance was under 0.5% ill the regIOn of 440-650 run. 0 run.

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A Research on the Health State According to Each of the Korean Constitution's Perceptual Level of Stress (한국인의 체질별 스트레스 인지정도에 따른 건강상태에 대한 연구)

  • Jeon, Eun-Young;Ko, Byung-Hee;Kim, Kwuy-Bun
    • Journal of Sasang Constitutional Medicine
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    • v.4 no.1
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    • pp.81-106
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    • 1992
  • The purpose of this study was to find out the causal relationship between perceptual level of stress and health state according to Korean constitutions and to analyze that effect on the Korean constitution's health state. Subjects of this study were 87 out patient department of constitution at Kyung-Hee Oriental Medicine Hospital. Data were collected by using interview with Questionaire during 6 months from Feb. 2 to June 31, 1991. The Measurement tools used by this researcher were Go's The Questionaire of Identify about constitution, Lee's stress scale and Go's modified Cornell Medical Index which were approved it's reliability and validity. All of the questionaires of were used after pre- test. For the purposes of the study, the collected data were analyzed by frequency, t-test, ANOVA and Pearson correlation. And then this research's issue was tested by SAS program's ANCOVA. The findings of this study was summarized as follow. 1. There was significantly differences in stress perceptual level in Korean constitution. (F=9.68, P=.000). The So Em In (小陰人) were higher than the other constitution on stress perceptional level. 2. In health state, there was significantly difference among Korean constitution. (F=6.654, P=.002). Also the So Em In (小陰人) was lower than the other constitution at health state. Therefore, it was considerate that So Em In (小陰人) was higher perceptual level of stress than the other constitution and the resulting poor health state. 3. Stressful perception was effected on the health state, as a result inverted correlation was constructed between stress perception and health state. (r=-.6034, P=.0001) 4. After exclusion of stress perceptual level, each of the Korean Constitution's health state was not difference (F=1.01, P=.37). It was mean that differences of the Korean Constitution's perceptual level of stress effected on the health state. Bacause So Em In (小陰人) had higher perceptual level of stress than other constitution (F=9.687, P=.000), in proportion to that one's health state was poor. From the results of this study, it could be concluded that the higher stress perceptual level according to Korean constitution, the poorer health state. Further study in this area needs to be consideration that in order to coping with stress, researcher grope for quality nursing intervention with more accurative assessment about Korean constitution.

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An Analytic Study on the Effect of Carbon Disulfide on the Blood Pressure (이황화탄소 폭로가 혈압에 미치는 영향에 관한 분석적 연구)

  • Park, Jong-Tae;Kim, Hae-Joon;Yum, Yong-Tae;Paek, Do-Myung
    • Journal of Preventive Medicine and Public Health
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    • v.27 no.3 s.47
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    • pp.581-595
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    • 1994
  • To investigate the effect of carbon disulfide on blood pressure, the BP measurements in the periodic health examination results and the medical records of factory clinic were reviewed. The study subjects were composed of 1336 male and 544 female workers, who were categorized into three groups by the exposure status-highly exposed, moderately exposed and non-exposed group. The results of the study were as follows; 1. The age-adjusted mean systolic and diastolic BP of male workers were 122.35 mmHg/79.11 mmHg in highly exposed, 121.57mmHg/79.05mmHg in moderately exposed and 122.67mmHg/82.27mmHg in non-exposed group. For female workers, BPs were 115.13mmHg/74.49mmHg in moderately exposed and 113.48mmHg/74.30mmHg in non-exposed group. 2. In multiple regression analysis of maximum BP against Age and tenure, the slope coefficients of age and tenure on the systolic BP were 0.379, 0.667 respectively and those on the diastolic BP were 0.331, 0.405 respectively in highly exposed male workers. Tenure was a significant variable in this study. For female workers, however the slope coefficients of tenure on BP were significant only for systolic BP of moderately-exposed group. 3. In multiple regression analysis of Bp against age, cumulative exposure index (CEI), cholesterol, all the variables showed significant slope coefficients in male, but age and CEI on systolic BP were significant for female workers (p<0.05). 4. In the multiple analysis of the amount of Bp change and the velocity of Bp change among male workers, the slope coefficients of tenure tended to increase as exposure level increased. Among female workers, the slope coefficients of tenure were significant on the amount of Bp change and the velocity of Bp change in moderately exposed group.

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A Study on the Performance Evaluation Index of Multi-Water Resources Connection and Continuous Utilization in Micro Water Grid (마이크로 워터 그리드에서 다중수원 연계·연속 활용 성능평가지표에 관한 연구)

  • Chae, Soo-Kwon;Lee, Sang-Hoon;Ah, Hong-Kyu
    • Journal of Environmental Impact Assessment
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    • v.28 no.6
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    • pp.556-567
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    • 2019
  • As the number of skyscrapers in micro water grid units such as green building and smart building is increasing in the world, the green building certification system is being implemented to solve problems such as increased demand for water resources and energy. However, researches on the use of sustainable water resources like water reuse and water conservation through linkage and continuous use of water resources, while the power and energy sectors are actively conducting R&D projects in the green building certification system on the micro water grid level. Therefore, this paper analyzes the characteristics and limitations of the water resources sector for the continuous utilization of multiple water sources in the green building certification system, due to the inadequate consideration of sustainability. Then investigates whether various water resources such as constants, nature, and alternative water resources are continuously used in and out of the green building or smart building and complex in the micro water grid unit to suggest evaluation methods and performance evaluation standards.