• Journal of Life Science
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• v.24 no.7
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• pp.713-720
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• 2014

In this study, the antioxidative and anti-inflammatory activities of Ardisia arborescens ethanol extract (AAEE) were evaluated using in vitro assays and a cell culture model system. AAEE exhibited potent scavenging activity against 1,1-diphenyl-2-picryl hydrazyl (DPPH), similar to ascorbic acid, which was used as a positive control. Moreover, AAEE effectively suppressed lipopolysaccharide (LPS)- and hydrogen peroxide ($H_2O_2$)-induced reactive oxygen species (ROS) in RAW 264.7 cells. Furthermore, AAEE induced the expression of antioxidative enzymes, heme oxygenase 1 (HO-1), and thioredoxin reductase 1 (TrxR1), in addition to their upstream transcription factor, nuclear factor-E2-related factor 2 (Nrf2), in a dose-dependent manner. The upstream signaling pathways of mitogen-activated protein kinases (MAPKs) might regulate the modulation of HO-1, TrxR1, and Nrf2 expression. On the other hand, AAEE inhibited LPS-induced nitric oxide (NO) formation, without cytotoxicity. Suppression of NO formation was the result of AEEE-induced down-regulation of inducible NO synthase (iNOS). The suppression of NO and iNOS by AAEE might be modulated by their upstream transcription factor, nuclear factor (NF)-${\kappa}B$, and activator protein (AP)-1 pathways. Taken together, these results provide important new insights into the antioxidative and anti-inflammatory activities of A. arborescens. AAAEE might represent a promising material in the field of nutraceuticals.

• Journal of Korea Technology Innovation Society
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• v.21 no.3
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• pp.1077-1100
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• 2018

The present study analyzed the effect of firms' external research and development (R&D) on corporate productivity, while investigating the moderating effect of firm size on the external R&D-productivity nexus. In the empirical analysis, we estimated South Korean manufacturing firms' total factor productivity (TFP) using the firm level data drawn from the Survey of Business Activities (Korea National Statistical Office) for the years 2006-2015. Thereafter, focusing on the role of external R&D and its interaction with the firm size in determining firms' TFP, the productivity function was estimated as well. To this end, we used ordinary least squares (OLS) and quantile regression to highlight the heterogeneous impacts of external R&D by companies' productivity level. Empirical results confirmed that firms' external R&D significantly enhanced corporate productivity in all manufacturing industries, from high-tech to low-tech. The moderating effect of firm size in determining the productivity effect of external R&D was not as prominent as in the case for internal R&D, which exhibited some degree of the size premium in the productivity-enhancing effect. These results suggest that regardless of the firm size, external R&D can be an important channel for corporate productivity improvement, and can be a particularly effective strategy for SMEs with relatively limited internal R&D capacities.

• Journal of Korean Society of Forest Science
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• v.99 no.5
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• pp.693-697
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• 2010

Biomass expansion factors that convert the timber volume (or dry weight) to biomass are used to estimate the forest biomass and account for the carbon budget on a national and regional scale. This study estimated the biomass conversion and expansion factors (BCEF), root to shoot ratio (R), biomass expansion factors (BEF) and ecosystem biomass expansion factor (EBEF) of Korean pine (Pinus koraiensis) forests based on direct field surveys and publications in Korea. The mean BCEF, BEF, and R was 0.6438 Mg $m^{-3}$ (n = 7, SD = 0.1286), 1.6380 (n = 27, SD = 0.1830), and 0.2653 (n = 14, SD = 0.0698), respectively. The mean EBEF, which is a simple method for estimating the understory biomass in Korean pine forest ecosystems, was 1.0218 (n = 6, SD = 0.0090). The values of the biomass expansion factors in this study estimated the Korean pine forest biomass with more precision than the default values given by the IPCC (2003, 2006).

• Korean Journal of Soil Science and Fertilizer
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• v.47 no.6
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• pp.518-524
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• 2014

Heavy metal pollution in agricultural field near at the abandoned metal mines has been a critical issue in Korea. In particular, bioaccumulation in plants can have detrimental effect on human health. Main objective of this research was to examine arsenic (As) concentration in soil with varied extraction methods and to determine bioaccumulation and biological transfer factor in different crops. Results showed that bioaccumulation ratio of As for total contents in soil was ordered leafy and stem vegetables (1.19%) > fruit bearing vegetables (0.79%) > pulses (0.40%) > root vegetables (0.36%) with different crop species. Among 6 different extraction methods, all of extraction methods showed high correlation ($R^2=0.87-0.97$) except DTPA ($R^2=0.25$) when comparing As concentration in soil extracted with different extractants and As concentration in each crops. Calculated biological transfer factor was ranged 0.002-0.018 depending on crop species. Overall, concentration of As in crops can be varied and best management practice for minimizing bioaccumulation of As should be considered depending on crop species.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2008.11a
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• pp.175-176
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• 2008

In this study, in order to develop the composition ceramics for lead-free ultrasonic motor, $[(K_{0.5}Na_{0.5})_{0.95}Li_{0.05}(Nb_{0.96}Sb_{0.04})]O_3$ ceramics were fabricated using $Ag_2O$ as sintering aid and a conventional mixed oxide process and their piezoelectric and dielectric characteristics were investigated according to the $SrTiO_3$ substitution. $SrTiO_3$ substitution enhanced density, dielectric constant$(\varepsilon_r)$ and electromechanical coupling factor$(k_p)$. However, mechanical quality factor was deteriorated. At the 0.5mol% $SrTiO_3$ substitution, density, electromechanical coupling factor$(k_p)$, dielectric constant$(\varepsilon_r)$ and piezoelectric constant$(d_{33})$ of specimen showed the optimum value of 4.437g/$cm^3$, 0.457, 1294, 265pC/N, respectively.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.12 no.3
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• pp.173-180
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• 1992

A feature typical of natural rivers is the bend. The purpose of this study is to examine hydraulic and morphometric characteristics in channel bend reach by the deterministic approach. Cross section shape factor, "As" is suggested for a new cahracteristic factor of channel bend reach analysis. The variation of this new factor along the river reach showed the location of the concentration of the force due to the current all over the reach, that is curved or not. Some general meander factors are used for correlation with new factor suggested, and the applicability of "As" is verified. The range R/W values are concentrated 2~4, the meanning of this value can be regarded to the warning for bank erosion or breaking. And this paper dealt with prediction of cross section bed shape variation.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2007.11a
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• pp.272-273
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• 2007

In this study, in order to develop the composition ceramics of lead-free ultrasonic motor, (Na,Li)$NbO_3-BaTiO_3$ ceramics were fabricated using a conventional mixed oxide process and their piezoelectric and dielectric characteristics were investigated according to the $BaTiO_3$, substitution. $BaTiO_3$ substitution enhanced density, dielectric constants$({\varepsilon}_r)$ and electromechanical coupling factor$(k_p)$. However, mechanical quality factor was deteriorated. At the $BaTiO_3$ substitution of 4mol%, density, electromechanical coupling factor$(k_p)$, dielectric constants$({\varepsilon}_r)$ and piezoelectric constant$(d_{33})$ of specimen showed the optimum value of $4.493g/cm^3$, 0.236, 175, 70pC/N, respectively.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.22 no.6
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• pp.484-488
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• 2009

In this study, in order to develop the lead-free piezoelectric ceramics with high piezoelectric and dielectric properties, $[(K_{0.5}Na_{0.5})_{0.95}Li_{0.05}(Nb_{0.96}Sb_{0.04})]O_3$ ceramics were fabricated using $Ag_2O$ as sintering aid and a conventional mixed oxide process and their piezoelectric and dielectric characteristics were investigated according to the $SrTiO_3$ substitution. $SrTiO_3$ substitution enhanced density, dielectric constant(${\varepsilon}_r$) and electromechanical coupling factor($k_p$). However, mechanical quality factor was deteriorated. And also, Curie temperature ($T_c$), and phase transition temperature($T_p$) were rapidly decreased. At the 0.5 mol% $SrTiO_3$ substitution, density, electromechanical coupling factor($k_p$), dielectric constant(${\varepsilon}_r$) and piezoelectric constant($d_{33}$) of specimen showed the optimum value of $4.437\;g/cm^3$, 0.457, 1294, 265 pC/N, respectively.

• Journal of Korean society of Dental Hygiene
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• v.22 no.4
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• pp.259-272
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• 2022

Objectives: To identify the factors influencing the turnover intention of registered South Korean dental hygienists and analyze the effect sizes. Methods: Overall, 54 studies based on criteria of PICO from 1 January 2000 to 11 January 2022 were extracted. The factors related to turnover intention were applied to the ecological system theory and categorized. Subsequently, the effect size of the correlations was comprehensively meta-analyzed by dividing it into protective and risk factors depending on the negative or positive correlation direction. Results: For the overall effect size, the protective factor (ES_r=-0.458) was higher than the risk factor (ES_r=0.352). In the protective factors, organizational commitment and perceived organizational support belonging to the microsystem yielded the largest effect size. Furthermore, as for risk factors, burnout, job stress, work harassment, role conflict, and emotional labor belonging to the microsystem showed a moderate effect size. Conclusions: Factors belonging to the microsystem demonstrated a large effect size in both protection and risk factors for dental hygienists' turnover intention. Additionally, the factor showing the largest effect size was protective factor categorized into a microsystem.

• Asian-Australasian Journal of Animal Sciences
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• v.10 no.2
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• pp.233-239
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• 1997

A mammary epithelial cell line (MAC-T) established as a model for lactation was utilized to identify and characterize effects of various hormones upon insulin-like growth factor binding protein secretion. Ligand and immunoblot analyses of conditioned media indicated that insulin-like growth factor binding protein-2 was secreted by MAC-T cells. Insulin-like growth factor-I stimulated insulin-like growth factor binding protein-2 secretion in a dose-dependent manner, but prolactin and bovine somatotropin did not alter insulin-like growth factor binding protein-2 secretion. Insulin increased and cortisol decreased insulin-like growth factor binding protein-2 secretion. Effects of insulin-like growth factor-I on insulin-like growth factor binding protein-2 secretion support previous studies using primary cultures of bovine mammary cells and bovine fibroblasts. Effects of cortisol and insulin on insulin-like growth factor binding protein-2 secretion may be explained by changes in protein synthesis. In addition, supraphysiological doses of insulin can cross-react with the insulin-like growth factor-I receptor and stimulate insulin-like growth factor binding protein-2 secretion. MAC-T cells provide a model system to study mechanisms that regulate local insulin-like growth factor-I bioactivity.