• Journal of Microbiology and Biotechnology
• /
• v.12 no.4
• /
• pp.622-627
• /
• 2002

Diphtheria toxin repressor (DtxR) binds to approximately 30 to 35-bp regions containing an interrupted 9-bp inverted repeat within a 19-bp core sequence. The core sequence is fairly conserved and critical for DtxR binding. The flanking regions that are consisted of 5 to 8 more of nucleotides from the core are also required for DtxR binding. The nucleotides in both flanking regions are A-T rich. To examine whether the A-T nucleotides in both flanking regions from the core have significant roles for DtxR binding, a DNA fragment was constructed based on the diphtheria tox promoter/operator, and DNA fragments with substitution of A and T nucleotides In the flanking regions to G and C were also constructed. To assess the effect of these substitutions on binding of DtxR and repressibility by DtxR, $\beta$-galactosidase activity from lacZ fused to the region was assessed. Gel mobility shift of the region by purified DtxR was also examined. The DNA fragments containing the mutations in the flanking regions still exhibited repression and mobility shift with DtxR. The core segment with the mutation is still, therefore, recognized by DtxR. Nonetheless, the results from the assays indicated that the substitution significantly decreased repression of the operator by DtxR in vivo under high-iron condition and decreased binding of DtxR to the operator. These results suggest that A and T nucleotides fur both flanking regions are preferred for the binding of DtxR.

• Journal of the Korean Institute of Intelligent Systems
• /
• v.18 no.4
• /
• pp.572-578
• /
• 2008

We analyze the search space considered by the previously proposed R-CORE method for learning Bayesian network structures of large scale. Experimental analysis on the search space of the method is also shown. The R-CORE method reduces the search space considered for Bayesian network structures by recursively clustering the random variables and restricting the orders between clusters. We show the R-CORE method has a similar search space with the previous method in the worst case but has a much less search space in the average case. By considering much less search space in the average case, the R-CORE method shows less tendency of overfitting in learning Bayesian network structures compared to the previous method.

• Journal of Electrical Engineering and Technology
• /
• v.6 no.4
• /
• pp.527-534
• /
• 2011

In the present paper, the characteristics of Mega-Flux$^{(R)}$, JNEX-Core$^{(R)}$, amorphous and ferrite cores are compared to the inductor of buck-boost converters for Hybrid Electric Vehicles. Core losses are analyzed at the condition of 10 kHz sine wave excitations, and permeability fluctuations vs. temperature and magnetizing force will be analyzed and discussed. Under the specifications of the buck-boost converter for 20 kW THS-II, the power inductor will be designed with Mega-Flux$^{(R)}$ and JNEX-Core$^{(R)}$, and informative simulation results will be provided with respect to dc bias characteristics, core and copper losses.

• Journal of Sensor Science and Technology
• /
• v.28 no.4
• /
• pp.225-230
• /
• 2019

$Au@TiO_2$ core-shell decorated rGO nanocomposite (NC) was prepared using a simple solvothermal method followed by heat treatment for gas sensor application. The crystal structure and morphology of the composites were characterized by X-ray powder diffraction and transmission electron microscopy, respectively. The $NO_2$ sensing response of the $Au@TiO_2/rGO$ NC was tested at operating temperatures from $250^{\circ}C$ to $500^{\circ}C$, and was compared with those of the bare rGO and $Au@TiO_2$ core-shell NPs. The $Au@TiO_2/rGO$ NC-based sensor showed a far higher response than the rGO or $Au@TiO_2$ core-shell based sensors, with the maximum response detected when the operating temperature was $400^{\circ}C$. This improved response was due to the high rGO gas absorption capability for $NO_2$ gas and the catalytic effect of $Au@TiO_2$ core-shell NPs in oxidizing $NO_2$ to $NO_3$.

• Polymer(Korea)
• /
• v.26 no.2
• /
• pp.227-236
• /
• 2002

The structure of pregel state in thermoreversible poly(vinylidene fluoride)(PVDF) /propylene carbonate(PC) system was investigated by laser light scattering. It was found that the PVDF chain did not exist as a separate chain even in a very dilute concentration(i.e. 100 times more dilute than the gel formation concentration) but as a large spherical aggregate with the radius of gyration $R_G$, of 232 nm and the effective hydrodynamic radius $R_H$= of 407 nm at $40^{\circ}C$. Based upon experimental results such as $R_H/R_G$=ratio of 1.75 and the pattern of scattering intensity with a minimum, a core-shell type sphere model was suggested as a structure of the aggregate. According to this model, the radius of core part was estimated as 215 nm, the shell thickness as 192 nm, and the ratio of monomer density of the shell part to that of the core part as about 0.075.

• Journal of Dental Rehabilitation and Applied Science
• /
• v.31 no.2
• /
• pp.75-85
• /
• 2015

Purpose: The purpose of this study is to evaluate which FRC-posts were more distinguishable from core. Materials and Methods: Nine extracted single-rooted mandibular premolars with similar lengths (${\pm}0.5 mm$) and widths (${\pm}0.5 mm$) were endodontically treated and obturated. One specimen which the three roots were embedded in a cold mounting resin was made. 3 specimens were made by this method. Post spaces were prepared for the following post system: FRC $Postec^{(R)}$ Plus, MACRO-$LOCK^{TM}$ POST $ILLUSION^{TM}$ $XRO^{(R)}$, $Snowpost^{(R)}$. After three different posts were placed in the roots of a specimen, each three specimens received a direct core build-up: $Luxacore^{(R)}$ Dual A3, $Luxacore^{(R)}$ Dual blue, $Filtek^{TM}$ Z350 A1E. Digital images were taken of the post and core with and without air-blowing. We asked to fifty dentists and fifty dental college students which post was more clearly discriminated from the core. Results: In surveys, when core was $Luxacore^{(R)}$ Dual blue, among three types of posts people more easily discriminated the $Snowpost^{(R)}$ from core. When core was $Luxacore^{(R)}$ Dual A3, among three types of posts people similarly more easily discriminated $Snowpost^{(R)}$ from core. When core was $Filtek^{TM}$ Z350 A1E, among three types of posts people more easily discriminated distinguished MACRO-$LOCK^{TM}$ POST $ILLUSION^{TM}$ $XRO^{(R)}$ post from core. People more easily distinguished MACRO-$LOCK^{TM}$ POST $ILLUSION^{TM}$ $XRO^{(R)}$ post from core when temperature was lowered by air-blowing. Conclusion: Ability to discriminate between FRC-post and core is different according to color contrast. MACRO-$LOCK^{TM}$ POST $ILLUSION^{TM}$ $XRO^{(R)}$ posts are more discriminable when temperature is lowered by air-blowing.

• Journal of the Korea Institute of Military Science and Technology
• /
• v.12 no.1
• /
• pp.70-79
• /
• 2009

Currently, the investment on Research and Development(R&D) for defense core technology is continuously increasing to maintain advanced country's R&D level. In accordance with this trend, the national defense R&D investment management system is being more strengthening, and importance of performance evaluation is being emphasized more and more. However, the existing indicators of performance evaluation for defense core technology R&D is limited in efficient management because of the qualitative evaluation items and subjective allocation of points. In this paper, we developed a novel indicator for defense core technology R&D performance evaluation through domestic and foreign related literature and inquiry, brainstorming, and analysis techniques by Stepwise Multiple linear Regression(SMR) and Analytic Hierarchy Process(AHP). And we verified effectiveness of proposed indicators of performance evaluation by comparing with the existing evaluation indicators. Our proposed indicators for performance evaluation will create superiority performance on defense R&D fields.

• Journal of Dental Rehabilitation and Applied Science
• /
• v.25 no.3
• /
• pp.225-235
• /
• 2009

A common procedure of restoration of endodonticlly treated tooth with fiber-reinforced post is followed by core build-up after post cementation. However, this technique is complex and time-consuming. The aim of this study was to compare fracture strength of premolar, restored with various methods of core fabrications on fiber-reinforced posts and casting metal restoration. Forty five freshly extracted human mandibular premolars were obtained and devided into 5 groups acconding to the type of post and methods of core build-up. In Group A, D.T. $Light-post^{(R)}$ were cemented with $DUO-LINK^{TM}$ and then $LIGHT-CORE^{TM}$ was used for core restoration. In Group B, D.T. $Light-post^{(R)}$ and $DUO-LINK^{TM}$ were used for cementing in the postspace, and $DUO-LINK^{TM}$ was used again for core restoration. In Group C, $Light-post^{(R)}$ bonding and the core build-up were performed simultaneously by using $DUO-LINK^{TM}$. In Group D, $LuxaPost^{(R)}$ was bonded by using $LuxaCore^{(R)}-Dual$. Again, $LuxaCore^{(R)}-Dual$ was used for core restoration. In Group E, $LuxaPost^{(R)}$ bonding and the core build-up were performed simultaneously by using $LuxaCore^{(R)}-Dual$. Axial reduction was formed parallelly as possible and 45 degree bevel was made at buccal occlusal surface. Crowns were fabricated and cemented. Each tooth was embedded in self-curing acrylic resin to the level of 2mm below the CEJ. Specimens were fixed on universal testing machin such that the axis of the tooth was at 45 degree inclination to the horizontal plane, and compressive force was applied at a crosshead speed of 1mm/min until failure occurred. The mean fracture strength was the highest in group A followed by descending order in group B, D, E and C. However, there were no statistically significant differences between groups with regard to the fracture strength. The type of the post or build-up methods of the core does not seem to influence the fracture strength.

• IE interfaces
• /
• v.21 no.1
• /
• pp.96-108
• /
• 2008

This paper proposes the systematic design approach for developing the evaluation indicators that evaluate the candidate proposals in the national defense core-technology R&D projects. To improve the validity and fairness of the evaluation indicators, the existing evaluation process in a military and a public sector are surveyed and also the existing evaluation system of the core-technology R&D programs for the national defense is analysed and discussed. A new system for the evaluation indicators is designed by using the axiomatic design, factor analysis and the analytic hierarchy process. It is expected that the proposed evaluation indicators contribute to enhance the fairness and the reliability of the evaluation process for the proposal of the national defense core-technology R&D projects.

• Proceedings of the Korean Powder Metallurgy Institute Conference
• /
• 2006.09b
• /
• pp.1191-1192
• /
• 2006

Eventhough Fe-6.5 wt.% Si alloy shows excellent magnetic properties, magnetic components made of the alloy are not totally because of its extremely low ductility. In order to overcome this demerit of alloy, 6.7 wt.% Si alloy powders were produced by gas atomization and then post-processed to form magnetic cores. By doing so, the total core loss could be minimized by reducing both hysteresis and eddy current loss. From our experiments, we were able to achive a core loss of $390mW/cm^3$ at 0.1 T and 50 kHz through proper processes and a permeability $\mu_{eff}$ of 68 at low frequency.