• Journal of the Institute of Electronics Engineers of Korea SC
• /
• v.43 no.6 s.312
• /
• pp.61-67
• /
• 2006

In this paper it was introduced that embedded RFID Reader /Writer system including PXA255 ARM chip which enables the Tag signal to be used by data and video processing via IEEE 802.11 communication protocol. Embedded RFID R/W middle ware was developed which transmit the searched result in the data base using the received Tag signal via IEEE 802.11 communication protocol. Developed embedded RFID R/W system was composed of three parts - PXA255 ARM chid (Core Part) 13.56 MHz RFID Reader /Writer, wireless LAN for data communication with server and TFT-LCD terminal. Once this system receives the Tag signal through the serial port, it transmits the data through the wireless LAN to the server and it displays the received image data which was processed by the server onto the TFT-LCD screen. Embedded RFID R/W Middle ware transmits the received Tag signal from RFID R/W to the embedded system, which activates the socket program to connect to the window server via IEEE 802.11 communication protocol and transmits the Tag signal. Window server program searches the Database using this Tag information and displays the result on to the TFT-LCD window in the embedded system via IEEE 802.11 protocol.

• Fashion Information and Technology
• /
• v.11
• /
• pp.11-19
• /
• 2014

• Bulletin of the Korean Chemical Society
• /
• v.33 no.7
• /
• pp.2365-2368
• /
• 2012

The $11{\beta}$-hydroxysteroid dehydrogenase type 1 ($11{\beta}$-HSD1) enzyme is involved in modulation of glucocorticoid activity within target tissues. This enzyme may contribute to obesity and/or metabolic disease through its action in adipose or liver tissue. Inhibition of $11{\beta}$-HSD1 has major therapeutic potential for glucocorticoid-associated diseases, including obesity, diabetes (wound healing), and muscle atrophy. To develop such therapeutics, we performed a pharmacophore-based virtual screening (VS) for identification of novel $11{\beta}$-HSD1 inhibitors and found that the VS hit compounds show potent inhibition of $11{\beta}$-HSD1 enzyme activity. Further, we present a binding model for active compounds. The proposed pharmacophore may serve as a useful guideline for future design of new chemical entities as $11{\beta}$-HSD1-targeted antidiabetic agents.

• Molecules and Cells
• /
• v.43 no.10
• /
• pp.856-869
• /
• 2020

To elucidate the mechanism of action of HOXA11-AS in modulating the cisplatin resistance of nasopharyngeal carcinoma (NPC) cells. HOXA11-AS and miR-454-3p expression in NPC tissue and cisplatin-resistant NPC cells were measured via quantitative reverse transcriptase polymerase chain reaction. NPC parental cells (C666-1 and HNE1) and cisplatin-resistant cells (C666-1/DDP and HNE1/DDP) were transfected and divided into different groups, after which the MTT method was used to determine the inhibitory concentration 50 (IC₅₀) of cells treated with different concentrations of cisplatin. Additionally, a clone formation assay, flow cytometry and Western blotting were used to detect DDP-induced changes. Thereafter, xenograft mouse models were constructed to verify the in vitro results. Obviously elevated HOXA11-AS and reduced miR-454-3p were found in NPC tissue and cisplatin-resistant NPC cells. Compared to the control cells, cells in the si-HOXA11-AS group showed sharp decreases in cell viability and IC₅₀, and these results were reversed in the miR-454-3p inhibitor group. Furthermore, HOXA11-AS targeted miR-454-3p, which further targeted c-Met. In comparison with cells in the control group, HNE1/DDP and C666-1/DDP cells in the si-HOXA11-AS group demonstrated fewer colonies, with an increase in the apoptotic rate, while the expression levels of c-Met, p-Akt/Akt and p-mTOR/mTOR decreased. Moreover, the si-HOXA11-AS-induced enhancement in sensitivity to cisplatin was abolished by miR-454-3p inhibitor transfection. The in vivo experiment showed that DDP in combination with si-HOXA11-AS treatment could inhibit the growth of xenograft tumors. Silencing HOXA11-AS can inhibit the c-Met/AKT/mTOR pathway by specifically upregulating miR-454-3p, thus promoting cell apoptosis and enhancing the sensitivity of cisplatin-resistant NPC cells to cisplatin.

• Journal of Convergence for Information Technology
• /
• v.11 no.11
• /
• pp.125-136
• /
• 2021

Innovation is essential for the survival of a company in the fierce competitive environment of the global era of borders along with rapid technological development and changes from the environment. It is very important to secure your own competitive advantage. In this study, the relationship between internal R&D capability and organizational support as a company internal factor and external R&D capability, external knowledge search, and absorptive capability as a company external factor on performance was examined. As a result of the analysis, it was found that internal R&D capability, organizational support, and external knowledge search had a significant effect on absorptive capability, and innovation performance had a positive effect on new product performance. However, the mediating effect of absorptive capacity has not been verified, suggesting that absorptive capacity has a low correlation between innovation performance and new product performance, or that other important factors act between absorptive capacity and performance variables. The results of this study are expected to be utilized as useful guidelines when establishing R&D strategies in companies.

• Bulletin of the Korean Chemical Society
• /
• v.11 no.1
• /
• pp.31-33
• /
• 1990

We synthesized the novel complexes of (1,1-dimethyl-3,4-diphenyl-1-silacyclopenta-2,4-di ene-2,5-yldibenzene)bis(tricarbonylchromium) and tricarbonyl (R,R'-3,4,5-triphenyl-1-silacyclopenta-2,4-diene-2 -ylbenzene)chromium(R,R' = Me, R = Me/R' = Cl, R = Ph/R' = Cl) from the reaction of the corresponding R,R'-2,3,4,5-Tetraphenyl-1-silacyclopenta-2,4-dien e (abr. R,R'-TPSCp) with chromiumhexacarbonyl. These results reveal that chromium prefer to coordinate to the phenyl substituents of 1-silacyclospentadiene rather than the butadiene moiety of the ring.

• International Journal of Fuzzy Logic and Intelligent Systems
• /
• v.11 no.3
• /
• pp.190-196
• /
• 2011

In this paper, we introduce the concept of fuzzy (r, s)-semi-irresolute mappings on intuitionistic fuzzy topological spaces in Sostak's sense, which is a generalization of the concept of fuzzy semi-irresolute mappings introduced by S. Malakar. The characterizations for the fuzzy (r, s)-semi-irresolute mappings are obtained by terms of semi-interior, semi-${\theta}$-interior, semi-clopen, and regular semi-open.

• Proceedings of the Korean Society of Crop Science Conference
• /
• 2005.10b
• /
• pp.320-321
• /
• 2005

• Bulletin of the Korean Chemical Society
• /
• v.22 no.11
• /
• pp.1261-1263
• /
• 2001

• Journal of the Korean Society of Radiology
• /
• v.5 no.3
• /
• pp.155-159
• /
• 2011

The purposed of this study were measured the radiation exposure of patients and workers by generators, and the protection state for radiation facilities. The subject of the study by X-ray generators in university hospitals of capital area, we measured the maximum irradiation condition of 80 kVp, 200 mA, 0.1 second in the control entrance, control room window, entrance of radiography, adjacent site. The leakage dose per week was which the control entrance was 0.11 mR/week, control room window was 0.15 mR/week, entrance of radiography was 0.12 mR/week and adjacent site was 0.06 mR/week with X-ray unit the mean And the leakage mean dose was 0.11 mR/week. Diagnostic X-ray tubes must ensure that the leakage radiation in the maximum leakage dose in week emitted by the tube outside the useful beam does not exceed certain levels provided by standards.