• 제목/요약/키워드: R linkage

검색결과 247건 처리시간 0.025초

광감응형 아조벤젠기를 갖는 신규 플러렌 유도체의 합성과 물성분석 (Synthesis and Characterization of Novel Fullerene($C_{60}$) Derivative with Photoresponsive Azobenzene Group)

  • 한기종
    • 한국응용과학기술학회지
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    • 제31권1호
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    • pp.50-58
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    • 2014
  • A novel fullerene derivative with photoresponsive azobenzene group was designed and synthesized, and its photoresponsive properties were reported. Starting from 4-nitrophenol, compound 1, which is containing fullerene moiety connected to azobenzene group through covalent linkage was synthesized by 5 steps. All the intermediates and the final compound were characterized by $^1H$, $^{13}C$-NMR, FAB-Mass or elemental analysis. Compound 1 exhibited the expected photoresponsive behavior. Chloroform solution($10^{-5}M$) of it served to maximize the absorption at 351 nm corresponding to the trans-azobenzene chromophore. Irradiation of this solution with 365 nm light resulted in photoisomerization to cis-azobenzene, as evidenced by decrease in the absorbance at 351 nm and an increase in absorbance at 450nm. A photostationary state was reached within about 150 s. Thermal reversion to the original spectrum was observed over the course of about 6 h at room temperature in the dark. However, exposure to bright sun light for about 5 s also effect almost complete reversion to the trans-isomer. This indicates that there is no strong steric influence on the trans-cis reversible isomerization of compound 1.

Mediating effect of major satisfaction on the influence of critical thinking disposition on disaster recognition

  • Kim, Jung-ae;Seo, Eun-Hui;Kim, Chul-Jin
    • International Journal of Advanced Culture Technology
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    • 제6권1호
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    • pp.23-31
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    • 2018
  • The purpose of this study was to identify mediating effect of major satisfaction in the effect of critical thinking disposition on disaster recognition. For this study, 237 students of nursing students from universities in Jeollanam do participated in the study. The data collection was collected on Dec 1 to 7, 2017. The descriptive statistics was used to analyze general characteristics of participants, the differences in disaster recognition according to general characteristics were analyzed by t-test or ANOVA. Regression analysis was conducted to confirm the effect of critical thinking disposition on disaster recognition and Baron, R.M. And Kenny, D.A.'s mediation effect statistic analysis was used to confirm the mediating effect of major satisfaction in critical thinking disposition on disaster recognition. As a result, the critical thinking disposition affects the disaster recognition, and it was judged that the major satisfaction was mediating role. intellectual fairness sub-factor showed perfect mediating effect and confidence and general truth sub-factor showed partial mediating effect. Based on the above findings, it can be seen that not only critical thinking but also satisfaction with the major should be considered in order to increase the recognition of the sudden disaster. In this case, research for linking critical thinking disposition and major satisfaction is likely to be meaningful. Through the results of this study, we suggest the program development of a linkage between critical thinking disposition and major satisfaction to increase the recognition of disaster.

친환경 교통서비스의 도입효과 분석방법론 : 카쉐어링 서비스 사례 (A Methodology of Analyzing Effects of an Environmentally Friendly Transportation Service : The Case of Carsharing Service)

  • 윤병운;이종태;김지태
    • 산업공학
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    • 제23권4호
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    • pp.286-299
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    • 2010
  • Recently, as concerns about environmental improvement have increased, various environmentally friendly transportation services have been developed and introduced. However, the effect on the introduction of such services has been not analyzed through a systematic methodology and process. Therefore, this research aims at suggesting a framework to analyze the effect of an environmentally friendly transportation service and investigating the validity of the framework. To the ends, a process to analyze the degree of improvement in transportation systems and environments, the linkage with existing policies, and profitability of the service is proposed. In addition, the concept and value of carsharing service, a representative environmentally friendly transportation service are explained and then the effects of the service are examined in terms of the aforementioned analytic areas, respectively. The results of this research can be utilized to provide the validity of a newly developed environmentally friendly transportation service and reflected to the policies of transportation and environment.

한국산 동백나무겨우살이에서 추출한 수용성 리그닌-탄수화물 복합체의 구조분석 (Structural Analysis of Water Soluble Lignin-Carbohydrate Complex(LCC) Isolated from Korean Camellia Mistletoe(Pseudixus japonicus Hayata))

  • 최준원;안원영
    • Journal of the Korean Wood Science and Technology
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    • 제25권3호
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    • pp.1-7
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    • 1997
  • 한국산 동백나무겨우살이(Pseudixus japonicus Hayata)에 존재하는 수용성 리그닌-탄수화물 복합체를 구성하는 다당류의 구조를 밝히고 리그닌 성분과 다당류의 결합양식을 구명하고자, 냉 온수 추출한 수용성 리그닌-탄수화물 복합체(M-LCC-WE)를 DEAE Sephadex A-50로 중성분획(M-LCC-N)과 산성분획(M-LCC-A), 나머지분획(M-LCC-R)으로 세분화한 후 M-LCC-N과 M-LCC-A에 대하여 메틸화, 아세틸화, 그리고 DDQ 산화반응을 실시하였다. M-LCC-N을 구성하는 다당류는 ($1{\rightarrow}4$) 글리코시드결합의 arabinan과 ($1{\rightarrow}4$)나 ($1{\rightarrow}6$) 글리코시드결합의 galactan과 glucan으로 M-LCC-A의 다당류는 ($1{\rightarrow}4$) 글리코시드결합의 arabinan과 ($1{\rightarrow}6$) 글리코시드결합의 galactan이 다당류 주성분으로 밝혀졌으며 galacturonic acid가 결합되어 있기 때문에 산성적 성질을 나타내고 있었다. 또한 M-LCC-A에서는 galacturonic acid 의 carboxyl 그룹이 리그닌의 ${\alpha}$-와 ${\gamma}$-위치에서 ester결합이 존재함이 확인되었다.

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Genetic Algorithm based hyperparameter tuned CNN for identifying IoT intrusions

  • Alexander. R;Pradeep Mohan Kumar. K
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제18권3호
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    • pp.755-778
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    • 2024
  • In recent years, the number of devices being connected to the internet has grown enormously, as has the intrusive behavior in the network. Thus, it is important for intrusion detection systems to report all intrusive behavior. Using deep learning and machine learning algorithms, intrusion detection systems are able to perform well in identifying attacks. However, the concern with these deep learning algorithms is their inability to identify a suitable network based on traffic volume, which requires manual changing of hyperparameters, which consumes a lot of time and effort. So, to address this, this paper offers a solution using the extended compact genetic algorithm for the automatic tuning of the hyperparameters. The novelty in this work comes in the form of modeling the problem of identifying attacks as a multi-objective optimization problem and the usage of linkage learning for solving the optimization problem. The solution is obtained using the feature map-based Convolutional Neural Network that gets encoded into genes, and using the extended compact genetic algorithm the model is optimized for the detection accuracy and latency. The CIC-IDS-2017 and 2018 datasets are used to verify the hypothesis, and the most recent analysis yielded a substantial F1 score of 99.23%. Response time, CPU, and memory consumption evaluations are done to demonstrate the suitability of this model in a fog environment.

농식품산업의 변화와 연구·지도사업의 과제 -지역R&D와 현장지도의 강화를 위해- (The Research and Extension System with Agro-Food industry Development: To Strengthen The Regional R&D and On-Farm Bases Extension)

  • 최영찬
    • 농촌지도와개발
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    • 제20권4호
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    • pp.839-869
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    • 2013
  • 1980년대 말 농식품 시장이 개방된 이후 우리농업은 큰 변화를 거쳐왔다. 농식품 소비시장의 대형화로 주기적 대량거래가 요구되어, 축산과 원예 분야는 물론 농업의 전 분야에서 전업농이 성장하게 되었다. 이로 인해, 농업 현장에서는 생산, 가공, 마케팅, 경영 등을 포함한 포괄적인 현장지식의 필요성이 대두되었으며, 이를 뒷받침 할 FSR&E(영농체계연구 및 지도)의 개념이 지역 특화 시험장 형태로 1992년에 소개되었고, 2009년에는 농림수산식품과학기술법에 따른 농림수산과학기술위원회가 설립되었다. 그러나 여전히 연구사업에서 생산되는 지식과 현장에서 요구되는 지식 간에 차이가 발생하고 있어, 연구 지도사업의 변화를 요구하고 있다. 기초연구와 응용연구를 구분하고, 연구와 지도사업 간의 연계를 개선하며, 현장에서 필요로 하는 포괄적인 지식의 생산과 이전이 이루어져야 한다. 이 연구는 지역 농식품 R&D 체계의 리엔지니어링과 활성화 방안을 제시하고 한다. 각 지역 기관의 연구 지도 업무수행의 역할이 중복되거나 결핍되지 않고 효율적인 업무분배와 협력구조가 이루어지도록 지역 농식품 연구 지도 시스템의 변화가 필요하며, 품목중심의 농업현장 연구 지도(Commodity Based On-Farm R&E)를 실현하여야 한다. 이를 위해 중앙의 연구 지도 사업과는 별도로 인적자원과 인프라구축을 위한 정부의 예산지원이 필요하다. 현재 시군지역으로 이관된 지도기관들의 행정체제를 광역화하여, 일선 지도기관들의 포괄적이고 협력적인 연구와 지도사업이 이루어지도록 할 필요가 있다.

돼지 FABP3 Promoter 부위 내 신규 돌연변이 탐색과 근내지방도와의 연관성 분석 (Detection of Novel Mutations in the FABP3 Promoter Region and Association Analysis with Intramuscular Fat Content in Pigs)

  • 김재환;박응우;박정진;최봉환;김태헌;서보영;정일정;임현태;오성종;이정규;전진태
    • Journal of Animal Science and Technology
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    • 제47권1호
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    • pp.1-10
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    • 2005
  • Intramuscular fat content(lMF) is considered as one of major economic traits in the pig breeding and industry. In general, high IMF results in better meat quality. Several approaches to detect quantitative trait 10ci( QTL) for IMF indicated a strong possibility of the existence of a QTL related to IMF between the microsatellite marker SW71 and SW1881 on SSC6q. Porcine FABP3 has been considered as a candidate gene affecting IMF due to its physiological roles and position on the pig genome. Two novel mutations, g.-114T> C and g.-158T>G were detected by duplicate sequencing of the porcine FABP3 promoter region. These two mutations were identified as absolute linkage disequilibrium. The g.-158T> G mutation was used for investigating relationships with growth and fat deposition traits. The GG genotype of the g.-158T> G polymorphism showed highly negative effects(P< 0.01) on body weights at 3 and 12 weeks of age, and a positive effect(P< 0.05) on IMF. However, backfat thickness(BF) and carcass fat(CF) content were not significantly associated with the genotype. The result indicates that the novel mutations, identified in this study, could be utilized as possible genetic markers to improve IMF, independent with BF.

폐경 전후 여성의 요추 골밀도와 심혈관 위험인자와의 연관성 (The Relationship Between Lumbar Spine Bone Mineral Density and Cardiovascular Risk Factors in Premenopausal and Postmenopausal Women)

  • 김미영
    • 대한방사선기술학회지:방사선기술과학
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    • 제30권4호
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    • pp.365-371
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    • 2007
  • 최근 연구들은 골다공증과 동맥경화증의 병인 간의 연관성을 제시한다. 이 연구에서는 건강한 중년 여성에서 high-sensitivity C-reactive protein(hs-CRP), 지질 농도 등을 포함한 심혈관 위험인자들과 요추 골밀도의 상관관계를 분석하였다. 총 300명의 성인여성을 대상으로 하여 신체계측을 시행하였고, 공복혈당, 지질, hs-CRP를 포함한 심혈관질환 위험인자들을 측정하였다. 동맥경화지수는 총콜레스테롤 농도를 고밀도지단백 콜레스테롤 농도로 나누어서 계산하였다. Dual X-ray abosorptiometry를 이용하여 요추 골밀도를 측정하였다. 연구결과 연령, 수축기 및 이완기 혈압, 총 콜레스테롤, 고밀도지단백 콜레스테롤은 요추 골밀도와 음의 상관관계를 보였다. 통계적으로는 연령과 체질량지수, 고밀도지단백 콜레스테롤이 요추 골밀도와 의미 있는 상관관계를 보였다. 요추 골밀도에 영향을 미치는 심혈관 인자들은 연령과 고밀도지단백 콜레스테롤이 요추 골밀도($R^2=0.272$)의 독립적 위험인자로 나타났다.

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회귀분석기반의 자전거 직접수요추정 모형 구축 (Development of Regression-based Bike Direct Demand Models)

  • 이규진;김건욱;최기주
    • 대한토목학회논문집
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    • 제31권4D호
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    • pp.489-496
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    • 2011
  • 녹색교통수단의 하나인 자전거는 세계적으로 수요가 증가하고 있으며, 특히 TOD(Transit-Oriented Development)중심의 교통 도시 계획에서도 대중교통수단의 연계 수단으로써 핵심적 역할을 할 것으로 기대되고 있다. 본 연구는 통행자의 개인 가구 특성, 도시의 사회 경제적 특성, 도로 교통 특성, 기상 특성 등의 변수를 고려하여, 기존 연구와 차별성이 있는 자전거 수요추정 모형을 구축하였다. 본 연구에서 구축한 모형에는 인구밀도, 초등학생을 제외한 학생수, 승용차 대수, 자전거도로연장, 월평균 소득의 변수가 반영되었으며, 모형의 수정 $R^2$는 0.738로 비교적 설명력이 우수한 것으로 나타났다. 본 연구결과를 통해 특정 도시계획 지역의 자전거 수요를 예측할 수 있을 것으로 판단되며, 이는 현재 활발히 진행되고 있는 자전거시설 투자계획에서의 시설규모 결정 및 타당성 평가에 본 연구가 활용될 수 있을 것으로 기대된다.

Genetic analysis of clubroot resistance in Chinese cabbage using single spore isolate of Plasmodiophora brassicae and development of RAPD marker linked to its resistance gene

  • Cho, Kwang-Soo;Hong, Su-Young;Han, Young-Han;Yoon, Bong-Kyeong;Ryu, Seoung-Ryeol;Woo, Jong-Gyu
    • Journal of Crop Science and Biotechnology
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    • 제11권2호
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    • pp.101-106
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    • 2008
  • To identify inheritance of clubroot disease resistance genes in Chinese cabbage, seedling tests of $BC_1P_1,\;BC_1P_2$, and $F_2$ populations derived from $F_1$ hybrid(var. CR Saerona) using single spore isolate(race 4 identified with William's differential host) from Plasmodiophora brassciae were conducted. Resistance(R) and susceptible(S) plants segregated to 1:0 in backcross to the resistant parent. The $F_2$ population segregated in a 3(R):1(S) ratio. This result implied that the resistance of clubroot disease is controlled by a single dominant gene to the race 4 of P. brassicae in CR Saerona. To develop DNA markers linked to clubroot resistance genes, 185 plants of CR Saerona among $F_2$ populations were used. A total of 300 arbitrary decamer was applied to $F_2$ population using BSARAPD(Bulked segregant analysis-Randomly amplified polymorphic DNA). One RAPD marker linked to clubroot resistance gene in CR Saerona($OPJ_{1100}$) was identified. This marker was 3.1 cM in distance from resistance gene in $F_2$ population. This marker may be useful for a marker-assisted selection(MAS) and gene pyramiding of the clubroot disease resistant gene in Chinese cabbage breeding programs.

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