• 한국가스학회지
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• 제13권1호
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• pp.52-60
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• 2009

본 논문에서는 Risk-based design개념을 반영하여 체계적인 설계방향을 제시하고 현존하는 법에 더욱 안전한 방향으로 법안이나 규격을 수정할 수 있는 방안을 제시하려고 한다. 안전설계 부분의 초기설계 집중도 및 수준을 향상시키기 위하여 설계 초기단계에서부터 체계화된 안전설계 요소의 정보를 제공할 수 있는 새로운 Advanced Safety Analysis Table(ASAT)을 개발하였다. 또한 ASAT를 토대로 공정 트러블에 따른 안전장치를 선택하는 방법에 대한 가이드라인을 개발하였다. 개발된 ASAT, 공정 트러블에 따른 안전장치를 선택방법의 사례 연구로 NCC(Naphtha Cracking Center) 공정의 PGC(Process Gas Compressor)에 대한 ASAT를 구축하고 공정 트러블에 따른 안전장치를 선택한 결과를 분석하였다.

• 산업공학
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• 제25권3호
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• pp.347-356
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• 2012

The acquisition cost of defense weapon system has been continuously increasing because of art-of-technology of it. This phenomenon requires efficiency and transparency in the weapon system acquisition process through cost estimation. Therefore cost estimation is very important to the government acquisition programs to support decisions about funding and to evaluate resource requirement as a key decision point. The Commercial parametric cost estimating models have been using extensively to obtain appropriate cost estimates in early acquisition phase. These models have many restrictions to ensure the cost estimating result in Korean defense environment because they are developed based on foreign R&D data. Also estimation results are different from Korean defense industry accounting system. So, some studies have been tried to develop a CER (Cost Estimation Relationship) based on the Korean historical data. However, there are some restrictions to improve the predictability and ensure the stability of the developed singular CERs which consider the following data characteristics individually. The the abnormal conditions of data that is multicollinearity, outlier and heteroscedasticity under rack of the number of observations. In this paper, a CER's Linear Combining Model is proposed to overcome those limitations which guarantee more accurate estimation (25.42% higher precision) than other singular CERs. At least, this study is meaningful as a first attempt to improve the predictability of CER with insufficient data. The methodology suggested in this study will be useful to develop a complex Korean version cost estimating model development in future.

• Journal of Welding and Joining
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• 제28권6호
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• pp.35-39
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• 2010

Generally, ceramic material is very difficult to machine due to high strength and hardness. However, ceramic material can be machined at high temperature by plastic flow as metallic material due to the deterioration of the grain boundary glassy phase. Recently, a new method was developed to execute cutting process with CBN cutting tool by local heating of surface with laser. There are various parameters in LAM because it is a complex process with laser treatment and machining. During laser assisted machining, high power results in reducing of cutting force and increasing tool life, but excessive power brings oxidation of the surface. The effect of laser power, feed rate, cutting depth and etc. were investigated on the life of cutting tool. Chips were observed to find out suitable machining conditions. Chips of SSN had more flow-types than HIPSN. It means SSN is easier to machining. The life of cutting tool was increased with increasing laser power and decreasing feed rate and cutting depth.

• 한국동물위생학회지
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• 제32권3호
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• pp.281-286
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• 2009

Fluoroquinolones in muscle and egg were separated by liquid extraction and determined. The analysis was carried out using following conditions; C18 column ($150{\times}4.6mm$, $5{\mu}m$), mobile phase composed of D.W. (containing 0.4% triethylamine and phosphoric acid) : methanol : acetonitrile (780:100:120, v/v/v), quarternary pump at a flow rate of 0.9ml/min and $20{\mu}l$ of injection volume, fluorescence detector with EX 278nm/Em 456nm. The calibration range of seven fluoroquinolones showed linearity ($r^2{\geq}0.999$) at concentration range of $0.025{\sim}0.8{\mu}g/ml$. The recoveries in fortified muscle and egg represented more than 81.3%. The detection limits for ofloxacin, norfloxacin, ciprofloxacin, enrofloxacin, danofloxacin, saraloxacin and orbifloxacin were 3.1, 2.5, 3.6, 1.7, 0.9, 2.5 and $2.1{\mu}g/kg$, respectively. We also monitored fluoroquinolones residue in the sample (chicken muscle 182, cattle muscle 140, pig muscle 139, egg 212) using EEC-plate (E. coli ATCC 11303) screening and HPLC confirmation methods. The screening test results, fluoroquinolones, antibacterial substances were all negative.

• 한국결정성장학회지
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• 제26권2호
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• pp.80-83
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• 2016

본 연구에서는 고출력 자동차 헤드램프용 LD 에 적용 가능한 garnet 구조의 YAG : Ce 형광체 세라믹 플레이트를 제작하고 광학 특성을 분석하였다. 액상법을 이용하여 단분산된 구형 나노 YAG : Ce 입자를 합성하고 이를 $Al_2O_3$와 혼합하여 형광체 세라믹 플레이트를 제작하였다. 형광체 세라믹 플레이트의 두께를 $75{\mu}m$, $100{\mu}m$로 조절하여 두께에 따른 광 변환 효율, 열 소광(Thermal quenching), 휘도 및 색온도의 광학 특성을 비교하였다. 실험 결과, 광 변환 효율의 감소 폭은 모두 25 % 감소하였고, 열 소광, 최대 광 변환 효율 값, 최대 휘도 값은 $100{\mu}m$ 일 때 더 높게 나타났다.

• 한국전자파학회논문지
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• 제29권9호
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• pp.707-721
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• 2018

본 논문에는 30 cm 해상도를 갖는 소형 SAR(Synthetic Aperture Radar) 시스템 개발 결과를 소개하고, RAW 데이터 기반의 도플러 파라미터 추정 및 요동 보상 신호처리 알고리즘을 제시한다. 송수신 채널이 각각 2개이기 때문에 다중 편파 및 간섭계 영상 확보가 가능하며, 차량 탑재 시험을 통하여 다중 편파 SAR 데이터 획득 및 신호 처리 결과를 제시하였다. 플랫폼의 요동에 의한 잔여 위상 오차를 보상하는 알고리즘을 적용하였으며, 실제 차량 탑재 시험을 통하여 요동 보상에 따른 개선된 성능 결과를 제시하였다.

• 비파괴검사학회지
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• 제17권4호
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• pp.227-236
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• 1997

탄성파 전파 과정의 정량적인 이해와 그 가시화는 결함 탐지는 물론이고, 재료의 물성 평가에 매우 중요하다. 대상 재료가 이방성을 지닐 경우에 탄성파 전파 과정은 복잡해져서 전파 과정의 해석 및 가시화 작업은 탄성파를 이용하는 결함 탐지 및 재질 평가에서는 필수적이다. 이방성 재료에서는 탄성파의 속도가 방향에 따라서 달라짐은 물론이고, 위상 속도와 군 속도의 방향이 어긋나서 파면이 진행하는 방향과 에너지가 진행하는 방향이 달라진다(beam skewing 효과). 특히 복합재료와 같이 이방성이 큰 재료에서는 이 효과가 매우 크게 나타나므로 탄성파를 이용한 시험 결과를 해석하고자 할 때에는 반드시 전파 과정을 이해해야 한다. 이방성 재료에 대해 해석적인 접근에는 한계가 있어서 유한차분법(finite difference method: FDM)과 같은 수치 해석 방법이 유용하게 사용되고 있다. 본 연구에서는 탄성파 전파 과정을 해석할 수 있는 2차원 FDM 프로그램을 개발하고, 이를 이용하여 이방성 재료에서의 탄성파 전파에 대한 전산 시뮬레이션 결과를 비교 분석한다.

• 한국축산식품학회지
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• 제36권4호
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• pp.516-522
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• 2016

Goat milk is highly nutritious and is consumed in many countries, but the development of functional foods from goat milk has been slow compared to that for other types of milk. The aim of this study was to develop a goat milk protein hydrolysate (GMPH) with enhanced digestibility and better hypoallergenic properties in comparison with other protein sources such as ovalbumin and soy protein. Goat milk protein was digested with four commercial food-grade proteases (separately) under various conditions to achieve the best hydrolysis of α_s -casein and β-lactoglobulin. It was shown that treatment with alcalase (0.4%, 60℃ for 30 min) effectively degraded these two proteins, as determined by SDS-PAGE, measurement of nonprotein nitrogen content, and reverse-phase high-performance liquid chromatography. Hydrolysis with alcalase resulted in a significant decrease in β-lactoglobulin concentration (almost to nil) and a ~40% reduction in the level of α_s-casein. Quantification of histamine and TNF-α released from HMC-1 cells (human mast cell line) showed that the GMPH did not induce an allergic response when compared to the control. Hence, the GMPH may be useful for development of novel foods for infants, the elderly, and convalescent patients, to replace cow milk.

• 한국축산식품학회지
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• 제37권3호
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• pp.402-409
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• 2017

A novel peptide having free radical scavenging activity was separated, using an on-line high-performance liquid chromatography (HPLC) - ABTS screening method, from bovine skim milk fermented by Lactococcus lactis SL6 (KCTC 11865BP). It was further purified using reverse phase-HPLC (RP-HPLC) and sequenced by RP-HPLC-tandem mass spectrometry. The amino acid sequence of the identified peptide was determined to be Phe-Ser-Asp-Ile-Pro-Asn-Pro-Ile-Gly-Ser-Glu-Asn-Ser-Glu-Lys-Thr-Thr-Met-Pro-Leu-Trp (2,362 Da), which is corresponding to the C-terminal fragment of bovine ${\alpha}_{s1}$-casein (f179-199). The hydroxyl radicals scavenging activity ($IC_{50}$ $28.25{\pm}0.96{\mu}M$) of the peptide chemically synthesized based on the MS/MS data showed a slightly lower than that of the natural antioxidant Trolox ($IC_{50}$ $15.37{\pm}0.52{\mu}M$). Furthermore, derivatives of the antioxidant peptide were synthesized. The antioxidative activity of the derivatives whose all three proline residues replaced by alanine significantly decreased, whereas replacement of two proline residues in N-terminal region did not affect its antioxidative activity, indicating that $3^{rd}$ proline in C-terminal region is critical for the antioxidative activity of the peptide identified in this study. In addition, N-terminal region of the antioxidant peptide did not show its activity, whereas C-terminal region maintained antioxidative activity, suggesting that C-terminal region of the peptide is important for antioxidative activity.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7795-7801
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• 2015

The aim of the present research was to establish primary characteristics of electron beams for a Varian 2100C/D linear accelerator with recently developed PRIMO Monte Carlo software and to verify relations between electron energy and dose distribution. To maintain conformity of simulated and measured dose curves within 1%/1mm, mean energy, Full Width at Half Maximum (FWHM) of energy and focal spot FWHM of initial beam were changed iteratively. Mean and most probable energies were extracted from validated phase spaces and compared with related empirical equation results. To explain the importance of correct estimation of primary energy on a clinical case, computed tomography images of a thorax phantom were imported in PRIMO. Dose distributions and dose volume histogram (DVH) curves were compared between validated and artificial cases with overestimated energy. Initial mean energies were obtained of 6.68, 9.73, 13.2 and 16.4 MeV for 6, 9, 12 and 15 nominal energies, respectively. Energy FWHM reduced with increase in energy. Three mm focal spot FWHM for 9 MeV and 4 mm for other energies made proper matches of simulated and measured profiles. In addition, the maximum difference of calculated mean electrons energy at the phantom surface with empirical equation was 2.2 percent. Finally, clear differences in DVH curves of validated and artificial energy were observed as heterogeneity indexes were 0.15 for 7.21 MeV and 0.25 for 6.68 MeV. The Monte Carlo model presented in PRIMO for Varian 2100 CD was precisely validated. IAEA polynomial equations estimated mean energy more accurately than a known linear one. Small displacement of R50 changed DVH curves and homogeneity indexes. PRIMO is a user-friendly software which has suitable capabilities to calculate dose distribution in water phantoms or computerized tomographic volumes accurately.