• 정보와 통신
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• 제19권12호
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• pp.26-35
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• 2002

• 정보과학회지
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• 제33권11호
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• pp.9-18
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• 2015

• Archives of Pharmacal Research
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• 제25권2호
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• pp.143-150
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• 2002

Fluorescent probes bound to DNA typically display nanosecond decay times and reveal only nanosecond motions. We extend the time range of measurable DNA dynamics using $[Ru(pby)_2(dppz)]^{2+}$ (bpy=2.2'-bipyridine, dppz=dipyrido[3,2-a2',3'-c]phenazine) (RuBD) which displays a mean lifetime near 90 ns. To test the usefulness of RuBD as a probe for diffusive processes in calf thymus DNA, we compared the efficiencies of fluorescence resonance energy transfer (FRET) using three donors which display lifetimes near 5 ns for acridine orange (AO), 22 ns for ethidum bromide (EB) and 92 ns for RuBD, with nile blue (NB) as the acceptor. The F rster distances for AO-NB, EB-NB and RuBD-NB donor-acceptor pairs were 42.3, 52.3, and $30.6{\;}{\AA}$, respectively. All three donors showed dramatic decreases in fluorescence intensities and more rapid intensity decays with increasing NB concentrations. The intensity decays of AO and EB in the presence of varying concentrations of NB were satisfactorily described by the one-dimensional FRET model without diffusion (Blumen and Manz, 1979). In the case of the long-lifetime donor RuBD, the experimental phase and modulation somewhat deviated from the recovered values computed from this model. The recovered NB concentrations and FRET efficiencies from the model were slightly larger than the expected values, however, the recovered and expected values did not show a significant difference. Thus, it is suggested that the lifetime of RuBD is too short to measure diffusive processes in calf thymus DNA.

• Journal of Information Technology Applications and Management
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• 제30권2호
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• pp.1-18
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• 2023

Recently, as technology development has accelerated and product life cycles have been shortened, it is necessary to derive key product features from customers in the R&D planning and evaluation stage. More companies want differentiated competitiveness by providing consumer-tailored products based on big data and artificial intelligence technology. To achieve this, the need to correctly grasp the required quality, which is a requirement of consumers, is increasing. However, the existing methods are centered on suppliers or domain experts, so there is a gap from the actual perspective of consumers. In other words, product attributes were defined by suppliers or field experts, but this may not consider consumers' actual perspective. Accordingly, the demand for deriving the product's main attributes through reviews containing consumers' perspectives has recently increased. Therefore, we propose a review data analysis-based required quality methodology containing customer requirements. Specifically, a pre-training language model with a good understanding of Korean reviews was established, consumer intent was correctly identified, and key contents were extracted from the review through a combination of KeyBERT and topic modeling to derive the required quality for each product. RevBERT, a Korean review domain-specific pre-training language model, was established through further pre-training. By comparing the existing pre-training language model KcBERT, we confirmed that RevBERT had a deeper understanding of customer reviews. In addition, all processes other than that of selecting the required quality were linked to the automation process, resulting in the automation of deriving the required quality based on data.

• 한국광학회:학술대회논문집
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• 한국광학회 2004년도 제15회 정기총회 및 동계학술발표회
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• pp.248-251
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• 2004

근접장 초해상 기술 중 대표적인 Super-RENS (Super Resolution Near Field Structure) 기술을 이용하여 25GB 용량의 BD(Blu-ray Disc) 다음 세대로 예상되는 100 ${\sim}$ 200 GB 용량의 Media 및 기록 재생 기기를 개발하고자 한다. 현재까지 이 기술의 어려움이었던 Stability 특성은 10만회 재생 내구성을 확인하엿고 CNR (신호 대 잡음 비) 특성은 50 nm 미세 마크에 대하여 40 dB의 특성을 확보 하였다. 이 특성은 대략 75 GB에 대응하는 것으로 BD System을 그대로 사용하면서 달성한 세계 최고의 기록 밀도로 평가된다. 향후 과제는 Jitter. Error Rate등 실제 신호 특성의 확보로서, 이의 확보를 통하여 기술의 상품화 가능성이 확인될 것이다.

• Psychiatry investigation
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• 제15권12호
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• pp.1115-1120
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• 2018

Objective The Biological Rhythms Interview of Assessment in Neuropsychiatry (BRIAN) is a scale used to clinically evaluate disturbances in biological rhythm. In this study, we aimed to examine the reliability and validity of the Korean version of the BRIAN (K-BRIAN) in a Korean population. Methods A total of 181 participants, including 141 outpatients with bipolar disorder (BD; type I, 62; type II, 79) and 40 controls, were recruited. Construct validity was tested by comparing the mean K-BRIAN scores of the BD patients and control subjects. Concurrent validity was tested by evaluating the association between the K-BRIAN and the Morningness-Eveningness Questionnaire (MEQ). Results The mean K-BRIAN scores of the control subjects and patients with BD differed significantly (p<0.001). Particularly, the mean K-BRIAN score was considerably lower among control subjects (mean${\pm}$standard deviation=$35.00{\pm}8.88$) than among patients with BD type I ($41.19{\pm}12.10$) and type II ($50.18{\pm}13.73$). The Cronbach's alpha for the K-BRIAN was 0.914. The K-BRIAN was found to correlate with the MEQ (r=-0.45, p<0.001). Conclusion The findings affirm that the K-BRIAN has good construct validity and internal consistency. This suggests that the K-BRIAN can be used to assess biological rhythms in the Korean population, especially for patients with mood disorder.

• 정보화연구
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• 제10권1호
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• pp.47-62
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• 2013

본 논문에서는 각 기업의 혁신(R&D) 활동에 의한 산업별 특징 차이와 산업별 혁신(R&D)활동의 비교우위 행태를 살펴보았다. 분석방법은 기업을 공급자지배산업, 생산집약산업, 과학기반산업으로 분류하고 그 산업들 각각의 특징과 기업의 R&D 역량에 대한 산업별 비교우위를 한국직업능력개발원의 HCCP(인적자본기업패널) 자료를 사용하여 실증분석 하였다. 분석결과 R&D 역량의 과학기반산업 쏠림현상과 공급자지배산업의 비교우위 부족현상이 나타났다. 과학기반산업의 R&D 역량 확대에 치우친 경향은 특성화되어야 할 R&D 역량의 발전 속도가 늦어지고 있다는 것을 의미하며, 이에 따른 정책적 함의는 다음과 같다. 첫째, R&D 역량이 저조한 공급자지배산업에 특성화된 R&D 역량 지원이 필요하다. 둘째, 정책적 차원에서 R&BD(사업화 연계 기술혁신 지원)에 대한 지원이 강화되어야 한다. 셋째, 중소기업에서 산업별 R&D 역량의 하향 평준화를 보완해야한다.

• Transactions on Electrical and Electronic Materials
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• 제15권6호
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• pp.305-308
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• 2014

Organosilyl-modified and star-shaped poly (${\varepsilon}$-caprolactone) (m-PCL) was prepared, and added to polymethylsilsesquioxane (PMSSQ), to make composites. The end groups of m-PCL are chemically similar to PMSSQ, and m-PCL mixed well with PMSSQ in the composite. Porous PMSSQ film was made by further calcination of the composite film at elevated temperature. m-PCL-templated PMSSQ and the as-prepared porous PMSSQ were structurally, optically, and thermally characterized in thin films. The chemical binding of m-PCL and PMSSQ effectively suppressed the phase separation of PMSSQ and m-PCL during the curing process. After calcination at elevated temperature, there remained many pores in the PMSSQ matrix. The refractive indices of the resulting porous PMSSQ thin films decreased with increase of the film porosities, depending on the initial m-PCL loadings.

• 조명전기설비학회논문지
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• 제29권11호
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• pp.1-5
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• 2015

In this paper, we propose the optical system design for a medium sized LED marine lanterns which simplifies the multi-layer structure into a single structure. In order to satisfy the target fixed intensity(35,000cd) and vertical divergence($-2.5^{\circ}{\sim}-4.0^{\circ}$, $+2.5^{\circ}{\sim}+4.0^{\circ}$), we use the total internal reflection collimator lens. And a Monte Carlo simulation has been utilized to optimize a condition of a LED package, TIR lens and outside lens. The computer simulation results indicated that this LED marine lanterns can produce of a fixed intensity(35,382cd) and vertical divergence($-3.1^{\circ}{\sim}+2.5^{\circ}$). Using the this optical system, we achieve the target value of LED lanterns.

• 미생물학회지
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• 제25권4호
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• pp.262-273
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• 1987

pBR 322와 pBD9을 이용하여 Staphylococcus aureus에서 분리된 chloramphenicol 저항성(Cmr) plasmid인 pSBK 203상의 ori 부위를 cloning하였다. 또한 E. coli 내에서도 발현하는 pSBK 203상의 Cm 저항성 부위 및 cloning 된 ori 부위를 pBR 322에 재조합시켜 E. coli와 그람양성균인 Bacillus subtilis 양쪽 모두에서 복제되고 또 항생물질에 대한 저항성도 각각 발현되는 shuttle vector 구성을 시도하였다.