• Korean Institute of Interior Design Journal
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• no.8
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• pp.32-38
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• 1996

The main focus of this paper is to apply contemporary aesthetics and psychological study with interior design analysis. Up to now, the methodology of interior design analysis has been developed toward a more qualitative way. By the virtue of the perception , congnition , and information theory, which oriented toward a quantitative approach, it became possible to investigate interior space analysis to a more objective and scientific ways. The purpose of this study is to investigate Modern and Post-Modern interior - architectural style with quantitative analytical method. The subjective interior critique studied by intuitive research will be transferred to scientific way by using quantitative formula . Savoye Villa and Guardiola House were selected as study model, because each architectural works ware regarded as masterpieces of Modern and Post-Modern style. These two oppositional style model will be distinguished with mathematical quantity by calculating Iave , Hmax, and Redundancy formula.

• Analytical Science and Technology
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• v.27 no.3
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• pp.153-160
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• 2014

While variety of cases of studies about asbestos analysis methods are released internationally, the results of Asbestos Containing Materials (ACM) according to differences in the method of the analysis is becoming an issue. In this study, homogeneity ensured ACM samples were analyzed by visual estimation method and point counting method, and the result cound be used not only to improve the reliability on asbestos analysis of the institutions and analysts but also to obtain the basic data of Polarizing Light Microscope (PLM) analysis by comparing and evaluating. Asbestos analysis were divided into qualitative and quantitative analysis method. The quantitative analysis was performed by visual estimation method and point counting method (total 400 points) of EPA 600-R-93-116 method by using PLM. Firstly, The following was the result of homogeneity of the samples by ANOVA (Analysis of variance) and the results were satisfied. The results of qualitative analysis showed that the samples were chrysotile and amosite, and about the results of quantitative analysis, asbestos concentration determined by point counting method tend to be lower than concentrations determined by visual estimation method and also, pont counting method was a little more complicated and time-consuming.

• Journal of the Korean Operations Research and Management Science Society
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• v.1 no.1
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• pp.151-170
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• 1976

There are many cases of production processes which intermittently produce several different kinds of products for stock through one set of physical facility. In this case, an important question is what size of production run should be prduced once we do set-up for a product in order to minimize the total cost, that is, the sum of the set-up, carrying, and stock-out costs. This problem is used to be called scheduling of multiple products through a single facility in the production management field. Despite the very common occurrence of this type of production process, no one has yet devised a method for determining the optimal production schedule. The purpose of this study is to develop quantitative analytical models which can be used practically and give us rational production schedules. The study is to show improved models with application to a can-manufacturing plant. In this thesis the economic production quantity (EPQ) model was used as a basic model to develop quantitative analytical models for this scheduling problem and two cases, one with stock-out cost, the other without stock-out cost, were taken into consideration. The first analytical model was developed for the scheduling of products through a single facility. In this model we calculate No, the optimal number of production runs per year, minimizing the total annual cost above all. Next we calculate No$_{i}$ is significantly different from No, some manipulation of the schedule can be made by trial and error in order to try to fit the product into the basic (No schedule either more or less frequently as dictated by) No$_{i}$, But this trial and error schedule is thought of inefficient. The second analytical model was developed by reinterpretation by reinterpretation of the calculating process of the economic production quantity model. In this model we obtained two relationships, one of which is the relationship between optimal number of set-ups for the ith item and optimal total number of set-ups, the other is the relationship between optimal average inventory investment for the ith item and optimal total average inventory investment. From these relationships we can determine how much average inventory investment per year would be required if a rational policy based on m No set-ups per year for m products were followed and, alternatively, how many set-ups per year would be required if a rational policy were followed which required an established total average inventory inventory investment. We also learned the relationship between the number of set-ups and the average inventory investment takes the form of a hyperbola. But, there is no reason to say that the first analytical model is superior to the second analytical model. It can be said that the first model is useful for a basic production schedule. On the other hand, the second model is efficient to get an improved production schedule, in a sense of reducing the total cost. Another merit of the second model is that, unlike the first model where we have to know all the inventory costs for each product, we can obtain an improved production schedule with unknown inventory costs. The application of these quantitative analytical models to PoHang can-manufacturing plants shows this point.int.

• Analytical Science and Technology
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• v.30 no.2
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• pp.82-88
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• 2017

Adenophorae Radix (AR) is a frequently used medicinal herb; because of its popularity, products containing similar herbal products are often sold as substitutes, especially if their morphology is similar. However, any analytical method to identify AR based on quantitative analysis is not registered in Korea, Japan and China Pharmacopoeias. This study developed a simple HPLC method to discriminate between authentic AR and substitutes. Linoleic acid was used as a marker compound of AR. Our optimized HPLC-UV conditions included a mobile phase of 90 % acetonitrile under isocratic condition, and a flow rate of 1.0 mL/min at room temperature. Detection wavelength was set at 205 nm. Linoleic acid was detected at 13.5 minutes for a total analysis time of 20 minutes. The standard herb of AR contained 0.025 % of linoleic acid, while four authentic AR samples and eight substitutes contained 0.040~0.071 % and 0.004~0.014 %, respectively. Comparison of the linoleic acid concentrations of the sample types to reference AR showed that among 12 samples, only the four samples were authentic. Thus, our HPLC-UV method, along with our suggested content criterion for linoleic acid concentration, can be used for the quick and accurate determination whether the herbal products are authentic AR or substitute.

• Journal of Microbiology and Biotechnology
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• v.32 no.8
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• pp.976-981
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• 2022

Phenanthrenes are bioactive phenolic compounds found in genus Dioscorea, in which they are distributed more in peel than in flesh. Recent studies on phenanthrenes from Dioscorea sp. peels have revealed the potential for valuable biomaterials. Herein, an analytical method using high-performance liquid chromatography (HPLC) for quantitation of bioactive phenanthrenes was developed and validated. The calibration curves were obtained using the phenanthrenes (1-3) previously isolated from Dioscorea batatas concentrations in the range of 0.625-20.00 ㎍/ml with a satisfactory coefficient of determination (R²) of 0.999. The limit of detection (LOD) and the limit of quantification (LOQ) values of the isolated phenanthrenes ranged from 0.78-0.89 and 2.38-2.71 ㎍/ml, respectively. The intraday and interday precision ranged from 0.25-7.58%. The recoveries of the isolated phenanthrenes were from 95 to 100% at concentrations of 1.25, 2.5, and 5.0 ㎍/ml. Additionally, phenanthrenes (1-3) were found in all investigated peel extracts. Hence, the developed method was encouraging for the quantitative analysis of phenanthrenes in genus Dioscorea.

• YAKHAK HOEJI
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• v.33 no.3
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• pp.156-160
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• 1989

A gas-chromatographic determination method of thiamin which use a quantitative cleavage of thiamin to 4-methyl-5-(2-hydroxyethyl)thiazol [I] and solvent extraction of the analyte prior to GC injection was modified. A column chromatographic procedure using a reversed phase, high capacity solid phase cartridge was applied to the clean-up of the analyte. Thiazol derivative[I] was quantitatively recovered upon the column method. Acetanilide, an internal standard, has a good recovery through the analytical procedure. The method has analytical precision of 2% or less in the coefficient of variation.

• Analytical Science and Technology
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• v.21 no.5
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• pp.438-441
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• 2008

We have developed an alternative to the internal chemical reference based on a calibrated reference signal which is not a real NMR line but an electronically produced signal (HERETIC) and determined the phosphorus concentration using this method. The area ratio of HERETIC and sample peaks obtained from the standard samples was used to measure the concentrations of different samples directly. The analysis of phosphorus by this method showed the excellent linear regression coefficient ($R^2=0.9999$) for the concentration range from 20 ppm to 500 ppm with HERETIC peak as reference.

• Journal of the Korean Society of Safety
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• v.5 no.3
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• pp.8-26
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• 1990

It is important to have exact information about the contact pressure distribution in the design of connected parts of machines and structures. In previous works, stress analyses on a two body contact problem have been carried out in large numbers. Besides, the measurement of contact stress is important to confirm the adequateness of the theoretical analysis, to verify appropriateness of Hertzian contact theory and to know the practical pressure distribution, but an excellent measuring method con't be found at present. Therefore, a quantitative measurement of contact pressure by means of ultrasonic waves using a normal probe and an angle has been proposed to measure the contact pressure distribution between two rough flat surfaces. At first, in a new proposed calibration method, the relation between mean contact pressure and sound pressure of reflected waves is obtained by using calibration blocks with various surface roughnesses made of the same material as the rectangular section beams And then, this experimental results are compared with the analytical ones, and the utility of this method is discussed.

• Food Science and Preservation
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• v.24 no.6
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• pp.795-801
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• 2017

Aralia elata Seemann (AE) has long been used as a folk medicine for the treatment of various diseases including diabetes mellitus, anti-arthritic, and anti-gastric ulcer agent in Korea, Japan, and China. This study was performed to establish a simple and reliable HPLC/UV analytical method for determination of most active anti-hypertensive compound, a 3-O-${\alpha}$-L-rhamnopyranosyl($1{\rightarrow}$2)-${\alpha}$-L-arabinopyranosyl hederagenin 28-O-${\beta}$-D-xylopyranosyl($1{\rightarrow}6$)-${\beta}$-D-glucopyranosylester (HE) for the standardization of the shoot extract of AE as a health functional food ingredient. The quantitative analytical method of HE was optimized by HPLC analysis using reverse-phase C18 column at $40^{\circ}C$ with $H_2O$ and acetonitrile (70:30, v/v) as an isocratic mobile phase at a flow rate of 1.0 mL/min and detection wavelength of UV 205 nm. This HPLC/UV analytical method showed good specificity and high linearity in the tested range of 0.03125-2.0mg/ml with excellent coefficient of determination ($R^2$) of 0.9999. The limit of detection and limit of quantification were $12.0{\mu}g/mL$ and $36.5{\mu}g/mL$, respectively. Relative standard deviation (RSD) values of data from intra- and inter-day precision were less than 0.2% and 0.1%, respectively. These results indicate that the established HPLC/UV analytical method is very simple, specific, precise, accurate, and reproducible and thus can be useful for the quantitative analysis of HE as a functional anti-hypertensive compound in AE extract.

• Mass Spectrometry Letters
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• v.9 no.1
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• pp.30-36
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• 2018

A quantitation method for free amino acids in human serum was developed using a stepwise-dilution method and a bimodal cation exchange (CEX)/hydrophilic interaction liquid chromatography (HILIC)-tandem mass spectrometry system equipped with an electrospray ionization source (ESI/MS/MS). This method, which was validated using quality control samples, was optimized for enhanced selectivity and sensitivity. Dithiothreitol (DTT) was used as a reducing agent to prevent the oxidation of a serum sample ($50{\mu}L$), which was then subjected to stepwise dilution using 3, 30, and 90 volumes of acetonitrile containing 0.1% formic acid. Chromatographic separation was performed on an Imtakt Intrada Amino Acid column ($50mm{\times}3mm$, $3{\mu}m$) in mixed mode packed with CEX and HILIC ligands embedded in the stationary phase. Underivatized free amino acids were eluted and separated within 10 min. As a result of the validation, the precision and accuracy for the inter- and intraday assays were determined as 2.11-11.51% and 92.82-109.40%, respectively. The lowest limit of quantification (LLOQ) was $0.5-4.0{\mu}g/mL$ and the matrix effect was 80.22-115.93%. The proposed method was successfully applied to the quantitative analysis of free amino acids in human serum.