• 제목/요약/키워드: Quantitative Method

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목향(Saussureae Radix)으로부터 Costunolide의 분리 및 함량분석 (Isolation and Quantitative Determination of Costunolide from Saussurea Root)

  • 김주선;지형준;장승엽;하광원;강삼식
    • 생약학회지
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    • 제30권1호
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    • pp.48-53
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    • 1999
  • Isolation and quantitative determination of costunolide from Saussurea lappa Clarke (Compositae) has been conducted by using HPLC method. Costunolide in an acetone extract from the crude drug was separated on a RP-18 column using a $MeOH-H_20$ mixture (65:35) as an eluent and the average content is about $1.32{\sim1.42%.$ The content of costunolide in dried extract was decreased by about 24% in seven days. However it showed a slight decrease in solution. It is highly recommended that quantitative determination of costunolide from Saussureae Radix should be conducted as early as possible after solvent extraction.

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Post-modernism 의 발생과 실내디자인의 수용에 관한 연구-모더니즘과 해체주의 실내 건축양식의 정량적 분석 및 해석을 중심으로 (A Study on the Origination of Post-Modernism and Its Acceptance on Interior Design -Concentrated on the Quantitative Analysis and Interpretation of Modern and Neo-Modern Interior Architectural Style-)

  • 이춘섭
    • 한국실내디자인학회논문집
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    • 제8호
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    • pp.32-38
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    • 1996
  • The main focus of this paper is to apply contemporary aesthetics and psychological study with interior design analysis. Up to now, the methodology of interior design analysis has been developed toward a more qualitative way. By the virtue of the perception , congnition , and information theory, which oriented toward a quantitative approach, it became possible to investigate interior space analysis to a more objective and scientific ways. The purpose of this study is to investigate Modern and Post-Modern interior - architectural style with quantitative analytical method. The subjective interior critique studied by intuitive research will be transferred to scientific way by using quantitative formula . Savoye Villa and Guardiola House were selected as study model, because each architectural works ware regarded as masterpieces of Modern and Post-Modern style. These two oppositional style model will be distinguished with mathematical quantity by calculating Iave , Hmax, and Redundancy formula.

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하고초(夏枯草, Prunellae Herba)로부터 Ursolic acid의 함량 분석 (Quantitative Determination of Ursolic acid from Prunellae Herba)

  • 김주선;이경순;장승엽;원도희;강삼식
    • 생약학회지
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    • 제31권4호
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    • pp.416-420
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    • 2000
  • Ursolic acid was isolated from Prunellae Herba (Prunella vulgaris var. lilacina) and identified by direct comparison with an authentic sample. A method of analysis for the evaluation of ursolic acid was developed based on extraction of ground plant material, followed by quantitative determination using capillary gas chromatography of the TMS derivative. Quantitative analysis by GC after derivatisation under mild silylating conditions showed 0.31% ursolic acid in 20 samples collected throughout regions of Korea while no ursolic acid was detected in the samples of the whole plant of Thesium chinense, a substitute for Prunellae Herba in southern regions of Korean peninsula.

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연삭가공 트러블슈팅을 위한 룰베이스 구성의 기초 (Basic Construction of Rule-Base for Grinding Trouble -shooting)

  • 이재경
    • 한국생산제조학회지
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    • 제9권4호
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    • pp.56-61
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    • 2000
  • Cognition and control of grinding trouble occurring during the grinding process are classified into a quantitative knowledge which depends on experimental data and qualitative knowledge which relies on skilful engineers. Grinding operations include a large number of functional parameters, since there are several ways of coping with grinding trouble. One is the qualitative method which depends on empirical knowledge utilizing the skilful experts from the workship, the other is the quantitative method which utilizes the experimental data obtained by a sensor. But, they are all difficult to accomplish from the grinding trouble-shooting system. The reason is that grinding troubles are now easily controlled in the quantitative method, and therefore, trouble-shooting has mainly relied on the knowledge of skilful engineers. Thus, there is an important issue of how a grinding trouble-shooting system can be designed and what knowledge is utilized among the large amount of grinding trouble information. In this paper, basic strategy to develop the grinding database of rule-based model, which is strongly depended upon experience and intuition , is described.

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Efficiency Estimation of Process Plan Using Tolerance Chart

  • Kim I.H.;Dong Zuomin
    • 한국CDE학회논문집
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    • 제11권2호
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    • pp.148-155
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    • 2006
  • This paper presents a new method for assessing the efficiency of production process plans using tolerance chart to lower production cost. The tolerance chart is used to predict the accuracy of a part that is to be produced following the process plan, and to carry out the quantitative measurement on the efficiency of the process plan. By comparing the values of design tolerances and their corresponding resultant tolerances calculated using the tolerance chart, the process plan that is incapable of satisfying the design requirements and the faulty production operations can be identified. Similarly, the process plan that imposes unnecessarily high accuracy and wasteful production operations can also be identified. For the latter, a quantitative measure on the efficiency of the process plan is introduced. The higher the unnecessary cost of the production, the poor is the efficiency of the process plan. A coefficient is introduced for measuring the process plan efficiency. The coefficient also incorporates two weighting factors to reflect the difficulty of manufacturing operations and number of dimensional tolerances involved. To facilitate the identification of the machining operations and the machined surfaces, which are related to the unnecessarily tight resultant tolerances caused by the process plan, a rooted tree representation of the tolerance chart is introduced, and its use is demonstrated. An example is presented to illustrate the new method. This research introduces a new quantitative process plan evaluation method that may lead to the optimization of process plans.

Detection of proximal caries using quantitative light-induced fluorescence-digital and laser fluorescence: a comparative study

  • Yoon, Hyung-In;Yoo, Min-Jeong;Park, Eun-Jin
    • The Journal of Advanced Prosthodontics
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    • 제9권6호
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    • pp.432-438
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    • 2017
  • PURPOSE. The purpose of this study was to evaluate the in vitro validity of quantitative light-induced fluorescence-digital (QLF-D) and laser fluorescence (DIAGNOdent) for assessing proximal caries in extracted premolars, using digital radiography as reference method. MATERIALS AND METHODS. A total of 102 extracted premolars with similar lengths and shapes were used. A single operator conducted all the examinations using three different detection methods (bitewing radiography, QLF-D, and DIAGNOdent). The bitewing x-ray scale, QLF-D fluorescence loss (${\Delta}F$), and DIAGNOdent peak readings were compared and statistically analyzed. RESULTS. Each method showed an excellent reliability. The correlation coefficient between bitewing radiography and QLF-D, DIAGNOdent were -0.644 and 0.448, respectively, while the value between QLF-D and DIAGNOdent was -0.382. The kappa statistics for bitewing radiography and QLF-D had a higher diagnosis consensus than those for bitewing radiography and DIAGNOdent. The QLF-D was moderately to highly accurate (AUC = 0.753 - 0.908), while DIAGNOdent was moderately to less accurate (AUC = 0.622 - 0.784). All detection methods showed statistically significant correlation and high correlation between the bitewing radiography and QLF-D. CONCLUSION. QLF-D was found to be a valid and reliable alternative diagnostic method to digital bitewing radiography for in vitro detection of proximal caries.

MMORPG 기반 게임의 몰입에 대한 정량적 분석 방법 (Quantitative Analysis of Flow in MMORPG Games)

  • 남병철;배기태
    • 한국게임학회 논문지
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    • 제11권3호
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    • pp.73-84
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    • 2011
  • 한국의 온라인 게임 시장은 전체 게임 시장의 56.4%를 차지한다. 그 중 MMORPG류의 게임은 온라인 게임시장의 45.27%의 큰 비중을 차지하고 있다. 그런데 대부분의 MMORPG 게임들은 기획과 개발과정에서 일반화된 기준이나 원칙이 아닌 특정 기획자의 주관적 판단에 거의 절대적으로 의존하고 있다. 이런 이유로 신작게임들 중 다수는 시장에서 인정받는 대작 게임과의 차별성이나 창의성을 찾아보기 어렵고 모방작이라는 오해를 받기 쉽다. 본 논문에서는 이런 문제점을 해결하기 위해 특히 게임 몰입 부분에 대한 공통적인 정보 제공 및 정량적 분석 방법을 제안한다. 또한 성공적인 MMORPG 게임들의 몰입에 대한 분석을 통해 제안한 방법이 게임 개발 시 효과적인 가이드가 될 수 있음을 입증해 보인다.

연삭가공 트러블슈팅을 위한 룰베이스 구성의 기초 (Basic Construction of Rule-Base for Grinding Trouble-shooting)

  • 이재경
    • 한국공작기계학회:학술대회논문집
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    • 한국공작기계학회 1999년도 추계학술대회 논문집 - 한국공작기계학회
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    • pp.492-497
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    • 1999
  • Cognition and control of grinding trouble occurring during the grinding process are classified into a quantitative knowledge which depends on experimental data and qualitative knowledge which relies on skillful engineers. Grinding operations include a large number of functional parameters, since there are several ways of coping with grinding trouble. One is the qualitative method which depends on empirical knowledge utilizing the skilful experts from the workshop, the other is the quantitative method which utilizes the experimental data obtained by sensor. But, they are all difficult to accomplish from the grinding trouble-shooting system. The reason is that grinding troubles are not easily controlled in the quantitative method, and therefore, trouble-shooting has mainly relied on the knowledge of skilful engineers. Thus, there is an important issue of how a grinding trouble-shooting system can be designed and what knowledge is utilized among the large amount of grinding trouble information. In this paper, basic strategy to develop the grinding database of rule-based rule, which is strongly depended upon experience and intuition, is described.

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Rapid Quantification of Salmonella in Seafood Using Real-Time PCR Assay

  • Kumar, Rakesh;Surendran, P.K.;Thampuran, Nirmala
    • Journal of Microbiology and Biotechnology
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    • 제20권3호
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    • pp.569-573
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    • 2010
  • A quantitative detection method for Salmonella in seafood was developed using a SYBR Green-based real-time PCR assay. The assay was developed using pure Salmonella DNA at different dilution levels [i.e., 1,000 to 2 genome equivalents (GE)]. The sensitivity of the real-time assay for Salmonella in seeded seafood samples was determined, and the minimum detection level was 20 CFU/g, whereas a detection level of 2 CFU/ml was obtained for pure culture in water with an efficiency of ${\geq}85%$. The real-time assay was evaluated in repeated experiments with seeded seafood samples and the regression coefficient ($R^2$) values were calculated. The performance of the real-time assay was further assessed with naturally contaminated seafood samples, where 4 out of 9 seafood samples tested positive for Salmonella and harbored cells <100 GE/g, which were not detected by direct plating on Salmonella Chromagar media. Thus, the method developed here will be useful for the rapid quantification of Salmonella in seafood, as the assay can be completed within 2-3 h. In addition, with the ability to detect a low number of Salmonella cells in seafood, this proposed method can be used to generate quantitative data on Salmonella in seafood, facilitating the implementation of control measures for Salmonella contamination in seafood at harvest and post-harvest levels.

Event-specific Detection Methods for Genetically Modified Maize MIR604 Using Real-time PCR

  • Kim, Jae-Hwan;Kim, Hae-Yeong
    • Food Science and Biotechnology
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    • 제18권5호
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    • pp.1118-1123
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    • 2009
  • Event-specific real-time polymerase chain reaction (PCR) detection method for genetically modified (GM) maize MIR604 was developed based on integration junction sequences between the host plant genome and the integrated transgene. In this study, 2 primer pairs and probes were designed for specific amplification of 100 and 111 bp DNA fragments from the zSSIIb gene (the maize endogenous reference gene) and MIR604. The quantitative method was validated using 3 certified reference materials (CRMs) with levels of 0.1, 1, and 10% MIR604. The method was also assayed with 14 different plants and other GM maize. No amplification signal was observed in real-time PCR assays with any of the species tested other than MIR604 maize. As a result, the bias from the true value and the relative deviation for MIR604 was within the range from 0 to 9%. Precision, expressed as relative standard deviation (RSD), varied from 2.7 to 10% for MIR604. Limits of detections (LODs) of qualitative and quantitative methods were all 0.1%. These results indicated that the event-specific quantitative PCR detection system for MIR604 is accurate and useful.