• BMB Reports
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• 제50권4호
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• pp.160-161
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• 2017

Proper maintenance of biological components is crucial for longevity and healthy aging. Although the role of homeostatic maintenance systems for DNA and protein in longevity is established, it remains largely unknown for RNA. In our recent work, we show that nonsense-mediated mRNA decay (NMD) promotes longevity in the roundworm C. elegans by enhancing RNA quality control. We find that the activity of NMD decreases during aging, raising the possibility that RNA quality declines in old animals. We then show that key components of NMD complex are required for prolonged lifespan in C. elegans. In addition, animals with reduced insulin/insulin-like growth factor-1 (IGF-1) signaling (IIS), a representative longevity model, display increased NMD activity. Thus, up-regulation of NMD appears to play crucial roles in longevity conferred by reduced IIS via enhancing mRNA quality control. As both IIS and NMD pathways are evolutionarily conserved, mammals including humans may be equipped with similar RNA quality control systems to achieve longevity.

• 한국환경과학회지
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• 제15권11호
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• pp.1017-1025
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• 2006

This study was conducted to evaluate characteristic of water duality in coastal sea of Incheon using a multivariate analysis. The analysis data in coastal sea of Incheon was aquired by the NFRDI data which was surveyed from March 1997 to November 2003. Eleven water quality parameters were determined on each survey The results were summarized as follow : Water quality in Incheon coastal sea could be explained up to 64.62% by three factors which were included in loading of fresh water and nutrients by the land(36.98%), seasonal variation(16.19%), and internal metabolism (11.24%). The results of time series analysis by factor score, in case of factor 1, station 1 influenced by Han river was shown to high factor score and station 3 located by outer sea was shown to low factor score. In case of factor 2, station 1 was appeared to high variation and station 3 was appeared to low variation. The result of cluster analysis by station was classified into three group that has different water quality characteristics. Especially, station 1 which affected by Han river and station 4 which affected by sewage treatment plant was appeared to considerable water quality characteristics against other station. In yearly cluster analysis, three group was classified and water quality in 2003 years due to high precipitation was different to another year. It could be suggested from these results that it is important to control discharge of fresh water by Han rivet and sewage treatment plant for water quality management of coastal sea of Incheon.

• Preventive Nutrition and Food Science
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• 제12권4호
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• pp.229-233
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• 2007

This study was conducted to investigate the quality characteristics of cookies added with different levels of tomato powder. Cookies were prepared with five different levels of tomato powder (0, 2.5, 5.0, 7.5, and 10.0%) and the physicochemical properties were examined. The pH of cookie dough decreased significantly by the addition of tomato powder (p<0.05). Crude protein and ash content of the cookies containing 5.0, 7.5 and 10.0% tomato powder were significantly higher than those of control and those with 2.5% (p<0.05). The spread factor of control cookie was lower than that of cookies containing 5.0, 7.5, and 10.0% tomato powder. The incorporation of tomato powder in cookies lowered the lightness values but increased redness and yellowness values. Rheology testing showed that cookies with 5.0, 7.5, and 10.0% tomato powder had significantly lower hardness value than control. Sensory evaluation revealed that overall desirability scores were not significantly different between control and tomato powder added groups. Therefore, cookies with up to 10.0% added tomato powder would be as acceptable as control cookies without depressing cookie quality.

• 대한디지털의료영상학회논문지
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• 제5권1호
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• pp.32-44
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• 2002

The role of radiology department has been greatly increased in the past few years as the technology in the medical imaging devices improved and the introduction of PACS (Picture Archiving and Communications System) to the conventional film-based diagnostic structure is a truly remarkable factor to the medical history. In addition, the value of using digital information in medical imaging is highly expected to grow as the technology over the computer and the network improves. However, the current medical practice, using PACS is somewhat limited compared to the film-based conventional one due to a poor image quality. The image quality is the most important and inevitable factor in the PACS environment and it is one of the most necessary steps to more wide practice of digital imaging. The existing image quality control tools are limited in controlling images produced from the medical modalities, because they cannot display the real image changing status. Thus, the image quality is distorted and the ability to diagnosis becomes hindered compared to the one of the film-based practice. In addition, the workflow of the radiologist greatly increases; as every doctor has to perform his or her own image quality control every time they view images produced from the medical modalities. To resolve these kinds of problems and enhance current medical practice under the PACS environment, we have developed a program to display a better image quality by using the ROI optical density of the existing gray level values. When the LUT is used properly, small detailed regions, which cannot be seen by using the existing image quality controls are easily displayed and thus, greatly improves digital medical practice. The purpose of this study is to provide an easier medical practice to physicians, by applying the technology of converting the H-D curves of the analog film screen to the digital imaging technology and to preset image quality control values to each exposed body part, modality and group of physicians for a better and easier medical practice. We have asked to 5 well known professional physicians to compare image quality of the same set of exam by using the two different methods: existing image quality control and the LUT technology. As the result, the LUT technology was enormously favored over the existing image quality control method. All the physicians have pointed out the far more superiority of the LUT over the existing image quality control method and highly praised its ability to display small detailed regions, which cannot be displayed by existing image quality control tools. Two physicians expressed the necessity of presetting the LUT values for each exposed body part. Overall, the LUT technology yielded a great interest among the physicians and highly praised for its ability to overcome currently embedded problems of PACS. We strongly believe that the LUT technology can enhance the current medical practice and open a new beginning in the future medical imaging.

• 경영과학
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• 제26권2호
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• pp.61-70
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• 2009

This study gives the quality factor evaluation of rubber gloves manufacturing, including a systematic classification of poor durability(internal quality factors) and look bad(external quality factors) as well as the types of defective items, along with the relationship between quality factors and the defective types. The relationship analysis between quality factors and the defective types are performed with AHP(Analytic Hierarchy Process) technique. The results of our study will be useful for quality management activities and manufacturing process in rubber gloves manufacturing companies.

• Child Health Nursing Research
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• 제14권4호
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• pp.396-404
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• 2008

Purpose: This study was conducted to identify the level of quality of family life, parental locus of control, and parental sense of competence, and to elucidate factors that influence family quality of life in the mothers of children with Attention Deficit/Hyperactive Disorder (ADHD). Method: A convenient sample of mothers from 6 child psychiatric clinics was used in this cross-sectional survey design. Questionnaires used for data collection included the following scales: Family Quality of Life, Parental Locus of Control-Short Form Revised, Parental Sense of Competence. Results: The level of family quality of life was mid-range. A positive relationship was found between Family Quality of Life and the research variables. The significant predictors of family quality of life were parental locus of control, parental sense of competence, and duration of medication and these variables accounted for 21.8% of the variance in family quality of life. Conclusions: These results indicate that family quality of life is an important factor which health care provider should assess and evaluate for children with ADHD and their families. The results of this study suggest that family quality of life is an important link with parental sense of competence and parental locus of control.

• Journal of Power Electronics
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• 제10권3호
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• pp.293-299
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• 2010

In this paper, a single-phase PFC (Power Factor Correction) dual boost converter based on input voltage estimation is studied for DC inverter air conditioner. It is focused on improving input power factor and power quality to satisfy the recent harmonic current regulation standards. Furthermore the input voltage estimation is introduced for price competitive products. A low cost and reasonable control system is implemented using a specified high-speed 32-bit microprocessor. Their effectiveness are verified through theoretical analysis and experiments.

• 품질경영학회지
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• 제7권2호
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• pp.22-28
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• 1979

The problem considered in this paper is to select the vital factor effect to the product quality through the experimental design and analysis of response surface, so as to control the quality improvement of industrial product. In this time, even through the mathematical model is unknown it could be applicable to control the quality of industrial products and to determine optimum operating condition for many technical fields, particulary, for industrial manufacturing process. When a set of data is available from an experimental design, it is often of interest 1:0 fit polynominal repression model in independent variables (eg, time, temperature, pressure, etc) the optimize the response variable (eg. yield, strength etc). This paper proposes a method known to obtain the optimum operating condition, and how to find the condition by using table of orthogonal array experiments, and optimization methodology of statistical model. A criterion can be applied determining to optimum operating conditions in manufacturing industry and improving the fit of response surface which may be used for prediction of responses and quality control of industrial products.

• 조명전기설비학회논문지
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• 제29권6호
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• pp.63-69
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• 2015

Energy Storage Systems (ESSs) are essential in the future power systems because they can improve power usage efficiency. In this paper, we propose the countermeasure for improving the power quality using coordinated control of BESS(Battery Energy Storage System) on EV connected system. To verify the performance of proposed scheme, we simulate on the actual power system of KEPCO and compare the results of voltage variation, frequency variation, and load factor with those of uncoordinated control. From the simulation results, we confirm that frequency and voltage deviation are significantly reduced with proposed coordinated control of BESS.

• 한국대기환경학회지
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• 제27권5호
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• pp.485-493
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• 2011

In Korea, PM (Particulate Matter) emissions caused by coal-fired power plants are measured by a system, so called Clean Air Policy Support System (CAPSS), which uses foreign emission factors. However, the system fails to reflect the characteristics of domestic power plants. In this regard, this study aims to develop local, accurate domestic emission factors. The study measured the amount of TSP (Total Suspended Particulates), PM10 and PM2.5 by collecting samples from the latter parts of pollution control devices which were installed at 3 bituminous-fired power plants and 3 anthracite-fired power plants. The results showed that the average concentrations of TSP, PM10 and PM2.5 measured at bituminous-fired power plants were 4.63 mg/$Sm^3$, 2.96 mg/$Sm^3$ and 3.07 mg/$Sm^3$ respectively, much higher than those from anthracite-fired power plants (2.96 mg/$Sm^3$, 2.47 mg/$Sm^3$ and 1.37 mg/$Sm^3$, respectively). In addition, bituminous-fired power plants showed higher ratios of PM10/TSP and PM2.5/TSP with 0.66 and 0.92, respectively, compared to 0.82 and 0.46, the ratios of PM10/TSP and PM2.5/TSP measured in anthracite-fired power plants. Emission factors based-on concentration measurements were also higher for bituminous-fired power plants, and PM with smaller particles tended to have bigger difference in emission factors between the two fuels. This study calculated the amount of PM emissions by using the estimated emission factors. When it comes to the PM emissions, it was less than that of CAPSS while similar to that of CleanSYS in its amount. It is expected that the emission factors developed by this study will be used in Korea replacing foreign emission factors currently used in Korea by ensuring the objectivity and reliability as domestic emission factors.