• International Journal of High-Rise Buildings
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• v.11 no.4
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• pp.315-320
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• 2022

With the rapid development of urbanization the problems of pedestrian-level wind comfort and natural ventilation of tall buildings are becoming increasingly prominent. The velocity at the pedestrian level ($\overline{MVR}$) and variation of wind pressure coefficients $\overline{{\Delta}C_p}$ between windward and leeward surfaces of tall buildings were investigated systematically through numerical simulations. The examined parameters included building density ρ, height ratio of building α_H, width ratio of building α_B, and wind direction θ. The linear and quadratic regression analyses of $\overline{MVR}$ and $\overline{{\Delta}C_p}$ were conducted. The quadratic regression had better performance in predicting $\overline{MVR}$ and $\overline{{\Delta}C_p}$ than the linear regression. $\overline{MVR}$ and $\overline{{\Delta}C_p}$ were optimized by the NSGA-II algorithm. The LINMAP and TOPSIS decision-making methods demonstrated better capability than the Shannon's entropy approach. The final optimal design parameters of buildings were ρ = 20%, α_H = 4.5, and α_B = 1, and the wind direction was θ = 10°. The proposed method could be used for the optimization of pedestrian-level wind comfort and natural ventilation in a residential area.

• Molecules and Cells
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• v.26 no.4
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• pp.338-343
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• 2008

An embryonic stem cell is a powerful tool for investigation of early development in vitro. The study of embryonic stem cell mediated neuronal differentiation allows for improved understanding of the mechanisms involved in embryonic neuronal development. We investigated expression profile changes using time course cDNA microarray to identify clues for the signaling network of neuronal differentiation. For the short time course microarray data, pattern analysis based on the quadratic regression method is an effective approach for identification and classification of a variety of expressed genes that have biological relevance. We studied the expression patterns, at each of 5 stages, after neuronal induction at the mRNA level of embryonic stem cells using the quadratic regression method for pattern analysis. As a result, a total of 316 genes (3.1%) including 166 (1.7%) informative genes in 8 possible expression patterns were identified by pattern analysis. Among the selected genes associated with neurological system, all three genes showing linearly increasing pattern over time, and one gene showing decreasing pattern over time, were verified by RT-PCR. Therefore, an increase in gene expression over time, in a linear pattern, may be associated with embryonic development. The genes: Tcfap2c, Ttr, Wnt3a, Btg2 and Foxk1 detected by pattern analysis, and verified by RT-PCR simultaneously, may be candidate markers associated with the development of the nervous system. Our study shows that pattern analysis, using the quadratic regression method, is very useful for investigation of time course cDNA microarray data. The pattern analysis used in this study has biological significance for the study of embryonic stem cells.

• Asian-Australasian Journal of Animal Sciences
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• v.16 no.6
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• pp.894-902
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• 2003

Prebiotics (peptides, N-acetyglucoamine, fructo-oligosaccharides, isomalto-oligosaccharides and galactooligosaccharides) were added to skim milk in order to improve the growth rate of contained Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium longum and Bifidobacterium bifidum. The purpose of this research was to study the potential synergy between probiotics and prebiotics when present in milk, and to apply modern optimization techniques to obtain optimal design and performance for the growth rate of the probiotics using a response surface-modeling technique. To carry out response surface modeling, the regression method was performed on experimental results to build mathematical models. The models were then formulated as an objective function in an optimization problem that was consequently optimized using a genetic algorithm and sequential quadratic programming approach to obtain the maximum growth rate of the probiotics. The results showed that the quadratic models appeared to have the most accurate response surface fit. Both SQP and GA were able to identify the optimal combination of prebiotics to stimulate the growth of probiotics in milk. Comparing both methods, SQP appeared to be more efficient than GA at such a task.

• Proceedings of the KIEE Conference
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• 1999.07g
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• pp.2856-2858
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• 1999

In this paper, the FPNN(Fuzzy Polynomial Neural Networks) algorithm with multi-layer fuzzy inference structure is proposed for the model identification of a complex nonlinear system. The FPNN structure is generated from the mutual combination of PNN (Polynomial Neural Network) structure and fuzzy inference method. The PNN extended from the GMDH(Group Method of Data Handling) uses several types of polynomials such as linear, quadratic and modifled quadratic besides the biquadratic polynomial used in the GMDH. In the fuzzy inference method, simplified and regression polynomial inference method which is based on the consequence of fuzzy rule expressed with a polynomial such as linear, quadratic and modified quadratic equation are used Each node of the FPNN is defined as a fuzzy rule and its structure is a kind of fuzzy-neural networks. Gas furnace data used to evaluate the performance of our proposed model.

• Journal of the Korean Data and Information Science Society
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• v.24 no.2
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• pp.391-399
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• 2013

Partially linear regression is capable of providing more complete description of the linear and nonlinear relationships among random variables. In support vector regression (SVR) the hyper-parameters are known to affect the performance of regression. In this paper we propose an iterative reweighted least squares (IRWLS) procedure to solve the quadratic problem of partially linear support vector regression with a modified loss function, which enables us to use the generalized approximate cross validation function to select the hyper-parameters. Experimental results are then presented which illustrate the performance of the partially linear SVR using IRWLS procedure.

• Journal of the Korean Data and Information Science Society
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• v.22 no.6
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• pp.1223-1232
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• 2011

Tong and Wang's estimator (2005) is a new approach to estimate the error variance using least squares method such that a simple linear regression is asymptotically derived from Rice's lag- estimator (1984). Their estimator highly depends on the setting of a regressor and weights in small sample sizes. In this article, we propose a new approach via a local quadratic approximation to set regressors in a small sample case. We estimate the error variance as the intercept using a ridge regression because the regressors have the problem of multicollinearity. From the small simulation study, the performance of our approach with some existing methods is better in small sample cases and comparable in large cases. More research is required on unequally spaced points.

• Communications for Statistical Applications and Methods
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• v.8 no.2
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• pp.311-317
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• 2001

It is necessary to check the linearity of selected covariates in regression diagnostics. There are various graphical methods using residual plots such as partial residual plots, augmented partial residual plots and combining conditional expectation and residual plots. In this paper, we propose the modified pseudolikelihood ratio test statistics based on these residual plots to test linearity of selected covariate. These test statistics which measure the distance between the nonparametric and parametric models are derived as a ratio of quadratic forms. The approximate distribution of these statistics is calculated numerically by using three moments. The power comparison of these statistics is given.

• Journal of the Korean Data and Information Science Society
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• v.16 no.4
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• pp.1087-1094
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• 2005

e-insensitive support vector regression(e-SVR) is capable of providing more complete description of the linear and nonlinear relationships among random variables. In this paper we propose an iterative reweighted least squares(IRWLS) procedure to solve the quadratic problem of e-SVR with a modified loss function. Furthermore, we introduce the generalized approximate cross validation function to select the hyperparameters which affect the performance of e-SVR. Experimental results are then presented which illustrate the performance of the IRWLS procedure for e-SVR.

• The Korean Journal of Applied Statistics
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• v.5 no.1
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• pp.29-39
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• 1992

A testing and estimation procedure is considered for changes at unknown time point in simple linear regression model. A test statistic of quadratic form is suggested. We also discuss the asymptotic distribution and its level control. The proposed method is compared with the likelihood ratio test through a example.

• Journal of Embryo Transfer
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• v.18 no.3
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• pp.215-225
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• 2003

This study was carried out to investigate the change of blood compositions by age in Hanwoo, and a total of 866 of Hanwoo, which consisted with 638 of steer and 228 of bulls, were used to measure serum concentrations. A multiple regression equation was estimated with collection age and blood composition as independent and dependent variables, respectively. Complicated regression equations for blood compositions in steer and bulls were IGF-I(cubic), calcium (linear), and IP(linear). Linear and cubic equations were fitted to testosterone in steer and creatinine in bulls, respectively. A cubic equation in steer and linear equation in bulls were fitted to HDLC. Equations of quadratic in steer and cubic in bulls were fitted to concentration of triglyceride, globulin, and A/G ratio. BUN was fitted by equations of cubic in steer and quadratic in bulls. TP and albumin were fitted by equations of quadratic in steer and linear in bulls. A cubic regression equation did not explain the change of cortisol by age in steer and bulls. A cubic regression equation did explain the change of glucose by age in steer, but not in bulls. Higher R-square values (R-SQUARE>0.1) were estimated to IGF-1, albumin, creatinine, Inorganic phosphorous(IP) and HDLC in steer, and testosterone, IGF-I, TP, albumin, glucose, creatinine, IP, and HDLC in bulls for the fitted regression equations of blood compositions. Therefore, IGF-I, albumin, creatinine, IP, and HDLC were regarded as comparatively large variation by age in steer and bulls.