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Bronchial Artery Embolization of Massive Hemoptysis -2 cases- (대량 객혈에 대한 기관지동맥 색전술 -치험 2례-)

  • 강경훈
    • Journal of Chest Surgery
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    • v.21 no.6
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    • pp.1117-1123
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    • 1988
  • Prolapse of the aortic valve is the main cause of insufficiency of the aortic valve as a complication of ventricular septal defect. Aortic insufficiency gets worse by the progress of prolapse of aortic valve due to lack of support of the valve and the hemodynamic effect of blood flow through the ventricular septal defect. This produces typical clinical picture, that may be serious and threatening when it is untreated. Type and timing for the surgical treatment of the ventricular septal defect with aortic insufficiency is considered. Among 113 ventricular septal defect, 9 patients of ventricular septal defect with associated aortic insufficiency were experienced from June. 1983 to June 1988 at the Department of Thoracic and Cardiovascular Surgery, Chon-Buk University Hospital. Male was 6 patients and female was 3 patients. Ages were from 7 years to 24years. 5 patients were from 10 to 19 years age. 3 patients were below 10 years age. The ratio of pulmonary blood flow to systemic f low [Qp/Qs] was 1.53 and in pulmonary vascular resistance, normal or slight increase was 7 patients, moderate 1 patient, and severe 1 patient. Ventricular septal defect was subpulmonic in 5 patients and infracristal in 4 patients. Prolapse of right coronary cusp was 7 patients, right and non coronary cusp 1 patient and non coronary cusp 1 patient. Teflon patch closure of ventricular septal defect was undertaken in 3 patients and primary closure in 1 patient. Among the 4 patients of defect closure alone, one patient performed valve replacement 7 months later due to progressive regurgitation and cardiac failure and the result was good. The other 3 patients were good result. Closure of ventricular septal defect and aortic valvuloplasty performed in 4 patients. 2 patients of these required valve replacement for the sudden intractable cardiac failure and died due to low cardiac output. The cause of intractable cardiac failure was tearing of repaired valve at the fixed site. The other 2 patients were good result. Closure of ventricular septal defect and valve replacement performed in 1 patient with good result.

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The Clinical Analysis of Patent Ductus Arteriosus (동맥관개존증의 임상적 고찰)

  • 김응중
    • Journal of Chest Surgery
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    • v.18 no.2
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    • pp.165-173
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    • 1985
  • A clinical analysis was performed n 706 uses of patent ductus arteriosus experienced at Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital during 27 years period from 1958 to 1984. Of the 706 patients of PDA, 244 patients were male and 462 patients were female and ages ranged from 2 months to 53 years old with the average age of 8.5 years. The chief complaints on admission were dyspnea on exertion and frequent URI in 58.9%, non specific symptoms such as palpitation and easy fatigability in 9.7%, symptoms of CHF in 2.0% and no subjective symptoms in 29.4%. On auscultation of heart, continuous machinery murmurs were heard in 82% and only systolic murmurs were heard in 18% of patients. On simple chest PA of patients, cardiomegalies were detected in 78% and there were increased pulmonary vascularities in 93% of patients. EKG findings were as followed; LVH 56.9%, BVH 12.6%, RVH 2.9% and WNL 27.6%. Cardiac Catheterizations were performed in 512 patients and mean Qp/Qs was 2.56 and mean systolic pulmonary artery pressure was 45mmHg. Operation methods were as followed; in patients in whom operations were performed on PDA only, ligation 94.3%, division 3.7% and ligation [0.5%] or trans-pulmonary artery suture closure [1.5%] under cardiopulmonary bypass 2.0% and in patients in whom operations were performed with associated anomalies, ligation 17.6%, division 2.4%, and ligation [44.7%] or trans-pulmonary artery suture closure [35.3%] under cardiopulmonary bypass 80%. 52 postoperative complications [8.4%] were developed in 42 patients [6.8%] and its were as followed; permanent or transient hoarseness 16 [2.6%], intraoperative rupture of PDA 8 [1.3%], recannalization 6 [1.[%], operative death 5 [0.8%], late death 4 [0.6%] and other miscellaneous complications 13 [2.1%]. 140 associated cardiac anomalies [19.8%] were found in 105 patients [14.9%] and its were as followed; VSD 68 [9.6%], COA 15 [2.1%], Subaortic discrete membrane 7 [0.9%], ASD 6 [0.8%], TOF 5 [0.7%] and other miscellaneous and

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Surgical Treatment of Atrial Septal Defect in Adult Patients (성인의 심방중격 결손의 외과적 치료)

  • Lee, Dong-Hyup;Lee, Jung-Cheul;Han, Sung-Sae
    • Journal of Yeungnam Medical Science
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    • v.9 no.2
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    • pp.321-326
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    • 1992
  • The study consisted of all patients over 35years old undergoing surgical repair of atrial septal defect for the period from June 1985, to August 1992. The following results were observed. 1. ASD was closed with patch in 11(73%) patients. 2. The relationship of pulmonary artery systolic pressure to Qp/Qs ratio was not significant. 3. Before operation 6 patients were in NYHA functional class II, 8 were in class III, After operation 8 patients were in class I, 6 were in class II. 4. Atrial fibrillation has persisted in 3 patients and returned regular rhythm in 1 patient after surgery. 5. There was no operative mortality and we had good surgical results regardless of patient's age.

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Increase of $CoQ_{10}$ Production Level by the Coexpression of Decaprenyl Diphosphate Synthase and 1-Deoxy-D-xylulose 5-Phosphate Synthase Isolated from Rhizobium radiobacter ATCC 4718 in Recombinant Escherichia coli

  • Seo, Myung-Ji;Im, Eun-Mi;Nam, Jung-Yeon;Kim, Soon-Ok
    • Journal of Microbiology and Biotechnology
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    • v.17 no.6
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    • pp.1045-1048
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    • 2007
  • Two genes, dps encoding decaprenyl diphosphate synthase and dxs encoding 1-deoxy-D-xylulose 5-phosphate synthase, were isolated from Rhizobium radiobacter ATCC 4718. DNA sequencing analysis of the dps and dxs genes revealed an open reading frame of 1,077 bp and 1,920 bp, respectively. The heterologous expression in Escherichia coli BL21(DE3) was carried out in order to identify their functions. Recombinant E. coli BL21(DE3) harboring the dps gene produced $CoQ_{10}$ as well as $CoQ_8$ and $CoQ_9$, whereas E. coli harboring only the dxs gene produced more $CoQ_8$ compared with the wild-type E. coli. Additionally, the coexpression of dps and dxs genes in E. coli was carried out. The recombinant E. coli harboring only the dps gene produced $0.21{\pm}0.04\;mg/l$ of $CoQ_{10}$, whereas the coexpressed E. coli with dps and dxs genes produced $0.37{\pm}0.07\;mg/l$ of $CoQ_{10}$. HPLC analysis also showed that the $CoQ_{10}$ fraction (100% of the total CoQs distribution) was increased from $15.86{\pm}0.66%$ (only dps) to $29.78{\pm}1.80%$ (dps and dxs).

Genes of Rhodobacter sphaeroides 2.4.1 Regulated by Innate Quorum-Sensing Signal, 7,8-cis-N-(Tetradecenoyl) Homoserine Lactone

  • Hwang, Won;Lee, Ko-Eun;Lee, Jeong-Kug;Park, Byoung-Chul;Kim, Kun-Soo
    • Journal of Microbiology and Biotechnology
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    • v.18 no.2
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    • pp.219-227
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    • 2008
  • The free-living photoheterotrophic Gram-negative bacterium Rhodobacter sphaeroides possesses a quorum-sensing (QS) regulatory system mediated by CerR-CerI, a member of the LuxR-LuxI family. To identify the genes affected by the regulatory system, random lacZ fusions were generated in the genome of R. sphaeroides strain 2.4.1 using a promoter-trapping vector, pSG2. About 20,000 clones were screened and 23 showed a significantly different level of ${\beta}$-gal activities upon the addition of synthetic 7,8-cis-N-tetradecenoyl-homoserine lactone (RAI). Among these 23 clones, the clone showing the highest level of induction was selected for further study, where about a ten-fold increase of ${\beta}$-gal activity was exhibited in the presence of RAI and induction was shown to be required for cerR. In this clone, the lacZ reporter was inserted in a putative gene that exhibited a low homology with catD. A genetic analysis showed that the expression of the catD homolog was initiated from a promoter of another gene present upstream of the catD. This upstream gene showed a strong homology with luxR and hence was named qsrR (quorum-sensing regulation regulator). A comparison of the total protein expression profiles for the wild-type cells and qsrR-null mutant cells using two-dimensional gel electrophoresis and a MALDI-TOF analysis allowed the identification of sets of genes modulated by the luxR homolog.

Hysteresis Loss in a $Sm_1Ba_2Cu_3O_{7-\delta}$ Coated Conductor under Simultaneously Applied Field and Current with Phase Differences (위상차를 갖고 변화하는 자기장과 전류가 동시에 가해진 $Sm_1Ba_2Cu_3O_{7-\delta}$ Coated Conductor의 자기이력 손실)

  • Lee, Sang-Moo;Jung, Ye-Hyun;Kwak, Ki-Sung;Rhee, Joon-Kyu;Yoo, Jae-Un;Youm, Do-Jun;Kim, Ho-Sup;Ha, Hong-Soo;Oh, Sang-Soo
    • Progress in Superconductivity
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    • v.10 no.2
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    • pp.92-98
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    • 2009
  • The magnetic field profiles near the surface of a $Sm_1Ba_2Cu_3O_{7-\delta}$ coated conductor(CC-tape) under magnetic field and current that were applied simultaneously with phase differences ${\phi}s$ were measured using scanning Hall probe method. Measurements were carried out along the elliptic load lines with $\phi=90^{\circ}\;and\;45^{\circ}$ for some $B_{peak},\;I_{peak}$ values. From the measured field profiles, sheet current density J(x, $B_a,\;I_a$) and magnetic flux density $B_0(x,\;B_a,\;I_a)$ profiles in the CC-tape were calculated. Using these J(x, $B_a,\;I_a$) and $B_0(x,\;B_a,\;I_a)$ profiles, we estimated the hysteresis energy loss Q in the CC-tape. The estimated Qs, together with our previous results for $\phi=0^{\circ}$ from [9], were compared with theoretical values based on Brandt's calculation.

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Operative Correction of Total Left Anomalous Pulmonary Venous Return - A Report of one case - (좌측 총폐정맥 환류이상의 수술 교정 - 1례 보고 -)

  • 류한영
    • Journal of Chest Surgery
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    • v.23 no.5
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    • pp.962-967
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    • 1990
  • The anomalous pulmonary venous return of the entire left lung was an extremely rare congenital anomaly. The reported surgical experience with correction of this disorder was limited. The 3-year-old female patient underwent an operation upon the unilateral total anomalous pulmonary venous return from the left lung, in which the left superior pulmonary vein drained into innominate vein and the left inferior pulmonary vein into the coronary sinus, in Yeungnam University Hospital. The symptoms were nonspecific except frequent upper respiratory infection. Cyanosis was not seen. On auscultatory findings, a grade 2/6 systolic ejection murmur was audible over left second intercostal space of left sternal border and second heart sound had an increased pulmonary component which was widely splitted. The electrocardiogram demonstrated a right ventricular hypertrophy and right axis deviation and chest X-ray showed slightly increased pulmonary vascularity and bulged pulmonary conus. The echocardiogram demonstrated increased right atrial, ventricular, and pulmonary arterial dimension, and also secundum atrial septal defect and enlarged coronary sinus. The cardiac catheterization confirmed the left-to-right with a Qp/Qs of 2.0: 1 and oxygen step-up was seen in pulmonary artery, right ventricle, right atrium, and left innominate vein, and the catheter was not been introduced into the left pulmonary vein. A median sternotomy incision was done. Left superior pulmonary vein was drained to the innominate vein through anomalous vertical vein and the left inferior pulmonary vein drained to right atrium through the coronary sinus. The diversion of the left inferior pulmonary vein to posterior wall of left atrium was done after division in the proximity of coronary sinus. The anomalous vertical vein was diverted to base of left atrial auricle and then a atrial septal defect was sutured directly. The postoperative course was uneventful and she was discharged on the eleventh postoperative day. In the postoperative follow-up-2 months, she has been well without specific problems.

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전자선 직접묘사에 의한 Deep Submicron $p^+$Poly pMOSFET 제작 및 특성

  • Kim, Cheon-Su;Lee, Jin-Ho;Yun, Chang-Ju;Choi, Sang-Soo;Kim, Dae-Yong
    • ETRI Journal
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    • v.14 no.1
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    • pp.40-51
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    • 1992
  • $0.25{\mu} m$ 급 pMOSFET소자를 구현하기 위해, $P^+$ 폴리실리콘을 적용한 pMOS를 제작하였으며, $p^+$ 폴리실리콘 게이트 소자에서 심각하게 문제가 되고 있는 붕소이온 침투현상을 조사하고 붕소이온 침투가 일어나지 않는 최적열처리온도를 조사하였다. 소자제조 공정중 게이트 공정만 전자선 (EBML300)을 이용하여 직접묘사하고 그 이외의 공정은 stepper(gline) 을 사용하는 Mix & Match 방법을 사용하였다. 또한 붕소이온 침투현상을 억제하기 위한 한가지 예로서, 실리콘산화막과 실리콘질화막을 적층한 ONO(Oxide/Nitride/Oxide) 구조를 게이트 유전체로 적용한 소자를 제작하여 그 가능성을 조사하였다. 그 결과 $850^{\circ}C$의 온도와 $N_2$ 분위기에서 30분동안 열처리 하였을 경우, 붕소이온의 침투현상이 일어나지 않음을 SIMS(Secondary Ion Mass Spectrometer) 분석 및 C-V(Capacitance-Voltage) 측정으로 확인할 수 있었으며 그 이상의 온도에서는 붕소이온이 침투되어 flat band전압(Vfb)을 변화시킴을 알았다. 6nm의 얇은 게이트 산화막 및 $0.1{\mu} m$ 이하의 LDD(Lightly Doped Drain) $p^-$의 얇은 접합을 형성함으로써 소자의 채널길이가 $0.2 {\mu} m$까지 짧은 채널효과가 거의 없는 소자제작이 가능하였으며, 전류구동능력은 $0.26\muA$/$\mu$m(L=0.2$\mu$m, V$_DS$=2.5V)이었고, subthreshold 기울기는 89-85mV/dec.를 얻었다. 붕소이온의 침투현상을 억제하기 위한 한가지 방법으로 ONO 유전체를 소자에 적용한 결과, $900^{\circ}C$에서 30분의 열처리조건에서도 붕소이온 침투현상이 일어나지 않음으로 미루어 , $SiO_2$ 게이트 유전체보다 ONO 게이트 유전체가 boron 침투에 대해서 좋은 장벽 역활을 함을 알았다. ONO 게이트 유전체를 적용한 소자의 경우, subthreshold특성은 84mV/dec로서 좋은 turn on,off 특성을 얻었으나, ONO 게이트 유전체는 막자체의 누설전류와 실리콘과 유전체 계면의 고정전하량인 Qss의 양이 공정조건에 따라 변화가 심해서 문턱전압 조절이 어려워 소자적용시 문제가 된다. 최근 바닥 산화막(bottom oxide) 두께가 최적화된 ONO 게이트 유전체에 대하 연구가 활발히 진행됨을 미루어, 바닥 산화막 최적화가 된다면 더 좋은 결과가 예상된다.

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Distribution of Lepidoptera on Forest Stand in Central Gangwon Area(II) (강원 중부지역 산림 내 나비류 분포에 관한 연구(II))

  • Chang, Suk Jun;Choi, Jong Won;Sim, Sang Jun;Kim, Jong Kuk
    • Journal of Forest and Environmental Science
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    • v.22 no.1
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    • pp.58-65
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    • 2006
  • This study investigated to distribution of Lepidoptera on the forest stands of cental Gangwon area from July to August in 2005. Collected Lepidoptera in the study area were total 462 individuals 123 genus 15 family and were collected 166 individuals, 66 genus, 15 family in Jumbong Mt., 159 individuals 65 genus 15 family in Eungbok Mt. and 137 individuals 40 genus 9 family in Odae Mt.. Dominant species in study area were Ampelophaga rubiginosa 54 individuals, Antheraea yamamai 35 individuals, Dendrolimus superans 27 individuals, Triphaenopsis jezoensis 14 individuals, Lymantria monacha 13 individuals. Shannon species diversity index(H') and Evenness index (J') were 1.52, 0.84 in Jumbong Mt., 1.69, 0.91 in Eungbok Mt., 1.87, 0.83 in Odae Mt. respectively. Community similarity index showed the lowest value in Jumbong Mt. and Odae Mt. as 0.11, the highest value in Jumbong Mt. and Odae Mt. as 0.28.

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Driving Pattern Recognition System Using Smartphone sensor stream (스마트폰 센서스트림을 이용한 운전 패턴 인식 시스템)

  • Song, Chung-Won;Nam, Kwang-Woo;Lee, Chang-Woo
    • Journal of Korea Society of Industrial Information Systems
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    • v.17 no.3
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    • pp.35-42
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    • 2012
  • The database for driving patterns can be utilized in various system such as automatic driving system, driver safety system, and it can be helpful to monitor driving style. Therefore, we propose a driving pattern recognition system in which the sensor streams from a smartphone are recorded and used for recognizing driving events. In this paper we focus on the driving pattern recognition that is an essential and preliminary step of driving style recognition. We divide input sensor streams into 7 driving patterns such as, Left-turn(L), U-turn(U), Right-turn(R), Rapid-Braking(RB), Quick-Start(QS), Rapid-Acceleration (RA), Speed-Bump(SB). To classify driving patterns, first, a preprocessing step for data smoothing is followed by an event detection step. Last the detected events are classified by DTW(Dynamic Time Warping) algorithm. For assisting drivers we provide the classified pattern with the corresponding video stream which is recorded with its sensor stream. The proposed system will play an essential role in the safety driving system or driving monitoring system.