• Journal of Applied Biological Chemistry
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• v.53 no.2
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• pp.99-104
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• 2010

The influences on antioxidant activities of the substituents ($R_1-R_4$) on benzo ring in 4-Methyl-2H-benzopyran-2-one analogues (1-23) were discussed quantitatively using three dimensional quantitative structure-activity relationships (3D-QSARs: Comparative molecular field analyses (CoMFA) and Comparative molecular similarity indice analyses (CoMSIA)) methods. The statistical qualities of CoMSIA models were better than those of CoMFA models and the CoMSIA 2 model was optimized model ($q^2$=0.700 & $r^2$=0.979). Also, the contribution ratios (%) of the optimized CoMSIA 2 model were H-bond donor field 43.5%, electrostatic field 41.8% and steric field 14.7% so that the antioxidant activity exhibited a strong correlation with H-bond donor and electrostatic factor of molecules. From the analytical results of the CoMSIA contour maps, if the positive charge favor group and H-bond donor disfavor group were placed in the $R_1-R_4$ positions on the benzo ring, it was predicted that the groups would raised the antioxidant activity.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 1992.10a
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• pp.3-3
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• 1992

타이어 Curing공정은 공기압 타이어의 제조시 상당히 정교한 단계를 거쳐서 이루어지며, 이는 타이어 설계에 큰 영향을 줄 뿐만아니라, 타이어의 성능에도 관건이 있다. 본 연구에서는 유한요소법을 이용하여 타이어의 molding 공정을 분석하였다. 유한요소해석 프로그램인 MARC가 Cured 타이어 내부의 Curing Bladder 팽창과정해석에 이용되었다. 비압축성 요소로 Curing Bladder를 모형화하였으며, MARC의 접촉문제해석기법(contact option)을 이용하여 Cured 타이어 내부와 Curing Bladder 외부의 접촉부위를 Simulation하였다. 본 연구의 주요 관심내용으로서는 Curing Bladder의 형상변화에 따른 Curing Bladder의 팽창거동해석과, Cured타이어와 Curing Bladder의 접촉부위에서 얻을 수 있는 접촉압력의 비교.검토이다. 타이어 Curing시 타이어와 Bladder의 Contact과정을 해석하여, 아래와 같은 결과를 도출하였다. Bladder의 형상은 Cylinderical 형상 보다는 Toroidal 형태가 접촉압 분포의 균일성 및 크기 측면에 서 우수한 것으로 판단된다. Curing Bladder의 증심선 부위 보다 이에서 약간 떨어진 부위에서 최대 접촉압력이 발생되며, 이는 타이어 내면의 굴곡현상과 깊은 관련이 있윰 것으로 사료된다. 타이어 Bead부의 Carcass 자연평형현상이 유지된 제품을 얻기위해서는, Side-Bead구간의 접촉압력 증가가 필요하며, 이를 위하여는 Bladder 형상이 Cylinderical 보다는 Toroidal 형태가 유리하고, Bead부의 Gage Down, 전체직경의 증가 및 높이의 증가가 유리한 것으로 판단된다. 본 연구 결과를 이용하여, 타이어 Curing과정에서 발생되는 불량제품의 원인파악 및 타이어 설계자가 원하는 제품생산의 불가능한 원인을 파악하는데 도움을 줄 것이다.를 C의 structure와 pointer를 기반으로 하게끔 변경시키고 이에 따르는 제반 변경 사항을 수정 보완하여 프로그램의 분석을 용이하게 하며 기능의 변경 및 추가가 수월하게 하였고 메모리를 동적으로 관리할 수 있게 하였다. 또한 기존의 smpl에 디버깅용 함수 및 설비(facility) 제어용 함수를 추가하여 시뮬레이션 프로그램 작성을 용이하게 하였다. 예를 들면 who_server(), who_queue(), pop_Q(), push_Q(), pop_server(), push_server(), we(), wf(), printfct() 같은 함수들이다. 또한 동시에 발생되는 사건들의 순서를 조종하기 위해, 동시에 발생할 수 있는 각각의 사건에 우선순위를 두어 이 우선 순위에 의하여 사건 리스트(event list)에서 자동적으로 사건들의 순서가 결정되도록 확장하였으며, 설비 제어방식에 있어서도 FIFO, LIFO, 우선 순위 방식등을 선택할 수 있도록 확장하였다. SIMPLE는 자료구조 및 프로그램이 공개되어 있으므로 프로그래머가 원하는 기능을 쉽게 추가할 수 있는 장점도 있다. 아울러 SMPLE에서 새로이 추가된 자료구조와 함수 및 설비제어 방식등을 활용하여 실제 중형급 시스템에 대한 시뮬레이션 구현과 시스템 분석의 예를 보인다._3$", chain segment, with the activation energy of carriers from the shallow trap with 0.4[eV], in he amorphous regions.의 증발산율은 우기의 기상자료를 이용하여 구한 결과 0.05 - 0.10 mm/hr 의 범위로서 이로 인한 강우손실량은 큰 의미가 없음을 알았다.재발이 나타난 3례의 환자를 제외한 9례 (75%)에서는 현재까지 재발소견을 보이지 않고 있다. 이러한 결과는 다른 보고자들과 유사한 결과를 보이고 있지만 아직까지 증례가 많지 않기 때문에 생존율을 얻

• The Inventors News
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• no.45
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• pp.1-16
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• 2006

'2006 여성발명 창의교실' 첫 수료식 개최/2006 대한민국 여성발명품 박람회/제12회 여성발명 우수사례 발표회/신세대 인터넷 용어, 상표 출원 증가/독창성가진 화투, 특허품으로 인정/대학 강의실에도 특허 열풍 분다/차세대 분자전자 메모리 특허 증가/교통카드 특허 이용료 협상 골머리/국제지식재산연수원, WIPO 공식 연수기관 지정/PCT, 국내단계 진입기간 31개월까지로 연장/직무발명 보상에 대한 길 더 넓어져/특허.실용신안, 권리 강화 되다/'특허행정체험단' 통해 고객 감동 실현/신규 발명교실 설치 계획 안내/사랑 확인해 주는 '연인의 잔' 발명/'무공해 플라스틱'으로 환경 사랑 나선다/중국, R&D 기지로 급부상하다/특허출원 실적, 대학별 빈부 격차 심해져/삼성,SDI,OLED 특허 출원 세계 최다/한국여성발명협회, 홈페이지 전면 개편/특허청, 국방과학연구소와 업무협력협정 체결/브랜드 경영 열풍, 지자체에도 분다/'DMB 기술표준과 전략적 특허분석' 발간/지렁이로 화장품, 비누 발명/건강 상식/시중 은행, 월드컵 미끼상품 못판다/역사 속의 발명품/하루 10문 발명교실/특허Q&A/조정숙 코코허브 대표/수원 매현중학교 발명교실/파마머리 발명, 올해로 1백주년/아이디어 착상 및 발명 기법/창의성은 우리의 밥줄이다/야마모토의 추잉껌/PSP진동기술 특허소송 소니패배/내셔널반도체, 특허 장난꾼 잡는다/특허청, '제7회 반도체 설계 공모전' 개최/KAIST 학생들, 특허청에서 '연구노트' 작성법 전수/특허법원, 전국법원 중 처음으로 구술변론 도입/한국여성발명협회 회원사 발명품 가이드/'2006 전국 발명표어 공모대회' 공고

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2008.04a
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• pp.185-188
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• 2008

This paper introduces the Bootstrap method for statistical analysis of noise and vibration spectrum in aeronautic and space fields. Generally, all components of a launch vehicle and its payloads are subjected to high intensive noise and vibration environment during the lift-off phase and the ascent phase through Mach =1 and Max Q. In order to verify their survivabilities against these severe vibroacoustic environments during qualification tests and acceptance tests, it is most important to estimate the proper upper limits of the environmental condition. Although NASA has typically utilized the Normal Tolerance Limit method in deriving these levels, the reference[1] says that the Bootstrap can be also an alternative method to estimate the maximum expected environments. In this paper, a general procedure of the Bootstrap method is summarized, and it is applied to analyze acceleration power spectral density functions, which were measured during acoustic test on the upper stage of KSLV-I.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.15 no.1
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• pp.28-39
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• 2004

The author reviewed various psychological measures of attachment types and variation on developmental stage approaches. Also, the point of reliabilities and validities of the measures were reviewed. SSP and AQS introduced first in infancy. Cassidy-Marvin's attachment type system, Crittenden's PAA, Main & Cassidy's attachment system, Doll play techniques and Family drawing analyses of attachment types introduced secondly for preschooler. IPPA for parent and peer attachment introduced for Childhood/Adolescence. Finally, AAI and ASQ for romantic attachment explained for adulthood.

• Journal of the Society of Naval Architects of Korea
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• v.35 no.4
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• pp.55-64
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• 1998

Using blind hole drilling method the residual stresses and welding deflections are measured for the cylindrical shell with various heat inputs and cylinder diameters. As a result, it is verified that the axial and hoop residual stresses which are generated near the weld part of cylinders are increased, as the heat inputs and cylinder diameters are increased. And experimental results show good agreements with those of precedent researchers. In this paper, it is validated that dominant parameters, heat input Q and the dimension of cylinder h/D have some effects on the magnitude and distribution of axial and hoop residual stresses and welding deflections. The empirical equations of residual stresses and welding deflections are made by using multiple linear regression with experimental results.

• Journal of the Korean Institute of Landscape Architecture
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• v.47 no.6
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• pp.115-128
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• 2019

Huam-dong is a representative area from the Japanese colonial period and is the space where most Japanese-style buildings remain in Seoul. Interest in modern cultural heritage continues to increase, including the registration of cultural properties in 2001, building assets in 2015, and the registration of cultural property units in 2018. As the debate continues over the necessity of preserving cultural heritage that reminds us of the Japanese colonial, there is a need for research to grasp the perceptions of stakeholders along with the perceived value of such spaces. This study identified the subjective perception types of the stakeholders concerned with the Japanese-style building group in Huam-dong, analyzed characteristics by types, and debated the issues. For this purpose, Q methodology, which is a statistical technique for measuring human self-subjectivity and extracting common human perspectives, was used. A literature study on the values of Huam-dong and modern cultural heritage was conducted, and a Q questionnaire based on five aspects of modern cultural heritage values (historical, architectural, sociocultural, landscape, and economic) was applied. The results of the study depicted three types of cognition and showed different attitudes toward the Japanese building group. This study found a conflict comparing the perceptional differences between the types of cognition. This study is meaningful in that it provides an in-depth approach to the perspectives of the stakeholders concerned with the Japanese-style buildings clustered in central Seoul. It is also meant to present a theoretical framework that can be applied to the use area as sustainable cultural heritage through the establishment of preservation and utilization of Japanese-style areas and conflict resolution.

• The Journal of the Korea Contents Association
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• v.9 no.4
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• pp.154-161
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• 2009

Thanks to the circumstance of digital convergence, most of the world TV and radio stations are gearing up for digitalisation of broadcasting. In this flux, digital switchover in South Korea should be completed by 2012 when transmission of analogue broadcasting signal will be ceased. According to the report, it shows only over 30% take up roughly so far, but there is no official survey from relevant organisation. It is very comparable with British digital switchover which is same year as S. Korea and has been reported 88% take up as of 2008 Q2. Yet the digital switchover in S. Korea inferred from this current is not a rosy future and even seems to be perilous. The purpose of this paper is to predict the media future of S. Korea at the view point of futurology and draw out the possibilities which enable to affect viewing behavior. In order to analyse it applies the futures wheel which is one of useful tools for future work. Consequently it suggests a number of scenarios how to cope with the impending situation in S. Korea.

• Journal of Life Science
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• v.31 no.12
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• pp.1057-1065
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• 2021

Alterations in mitochondrial DNA (mtDNA) copy numbers have been reported in patients with stomach cancer and suggested to play a role in gastric carcinogenesis or gastric cancer progression. However, changes in the levels of mitochondrial proteins or mtDNA-encoded oxidative phosphorylation (OXPHOS) proteins in gastric cancer remain unclear. In this study, we investigated mtDNA contents, mitochondrial protein levels, and mtDNA-encoded OXPHOS protein levels in gastric cancer tissues and cell lines. We correlated mtDNA copy numbers with clinicopathologic features of the gastric cancer samples used in this study and used quantitative PCR to analyze the mtDNA copy numbers of the gastric cancer tissues and cell lines. Western blot analysis was used for assessing the amounts of mitochondrial proteins and mtDNA-encoded OXPHOS proteins. Among the 27 gastric cancer samples, 22 showed a reduction in mtDNA copy numbers. The mtDNA content was increased in the other five samples relative to that in normal matched gastric tissues. Mitochondrial protein and OXPHOS protein levels were reduced in some gastric cancer tissues. However, mitochondrial protein and OXPHOS protein levels in gastric cancer cell lines were not always in line with their mtDNA contents. The mtDNA copy numbers were reduced in five gastric cancer cell lines tested in this study. In summary, this study reports a common reduction in mtDNA contents in gastric carcinoma tissues and cell lines, pointing to the possible involvement of mtDNA content alterations in tumorigenesis of the stomach.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.19 no.12
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• pp.1339-1349
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• 2008

In this paper, a nonlinear relationship between an input complex envelope and an output complex envelope of m-th harmonic zone is theoretically analyzed, and AM/$AM_m$ and AM/$PM_m$ are defined. A scheme to extract these characteristics from measured in-phase and quadrature-phase data is suggested. The proposed analysis is verified with a fundamental-fundamental and fundamental-third harmonic measurements for a InGaP power amplifier(PA). Based on the harmonic-band nonlinear analysis and extraction scheme, a new technique to send a signal in m-th harmonic band with a harmonic signal Linearization Digital Predistortion(DPD) scheme is presented. A numerical analysis and a Look-Up Table(LUT) based DPD algorithms to linearize output signal on m-th harmonic zone are developed. For a 16- and a 64-QAM input signals, a DPD for third harmonic signal linearization is implemented, and output spectrum and signal constellation are measured. The wholly distorted signals are linearized, and thus the measured Error Vector Magnitudes (EVM) are 6.4 % and 6.5 % respectively. The results show that a proposed scheme linearizes a nonlinearly distorted harmonic band signals. The proposed nonlinear analysis and predistortion scheme can be applied to multiband transmitter in next generation software defined radio(SDR)/cognitive radio(CR) wireless system.