• Journal of the Korean Society of Radiology
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• v.5 no.6
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• pp.401-407
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• 2011

The purpose of this study is to know the differences of MR spectra, obtained from normal volunteers by variable TE value, through the quantitative analysis of brain metabolites by peak integral and SNR between 1.5T and 3.0T, together with PRESS and STEAM pulse sequence. Single-voxel MR proton spectra of the human brain obtained from normal volunteers at both 3.0T MR system (Magnetom Trio, SIEMENS, Germany) and 1.5T MR system (Signa Twinspeed, GE, USA) using the STEAM and PRESS pulse sequence. 10 healthy volunteers (3.0T:3 males, 2 females; 1.5T : 3 males, 2 females) with the range from 22 to 30 years old (mean 26 years) participated in our study. They had no personal or familial history of neurological diseases and had a normal neurological examination. Data acquisition parameters were closely matched between the two field strengths. Spectra were recorded in the white matter of the occipital lobe. Spectra were compared in terms of resolution and signal-to-noise ratio(SNR), and echo time(TE) were estimated at both field strengths. Imaging parameters was used for acquisition of the proton spectrum were as follow : TR 2000msec, TE 30ms, 40ms, 50ms, 60ms, 90ms, 144ms, 288ms, NA=96, VOI=$20{\times}20{\times}20mm3$. As the echo times were increased, the spectra obtained from 3.0T and 1.5T show decreased peak integral and SNR at both pulse sequence. PRESS pulse sequence shows higher SNR and signal intensity than those of STEAM. Especially, Spectra in normal volunteers at 3.0T demonstrated significantly improved overall SNR and spectral resolution compared to 1.5T(Fig1). The spectra acquired at short echo time, 3T MR system shows a twice improvement in SNR compared to 1.5T MR system(Table. 1). But, there was no significant difference between 3.0Tand 1.5T at long TE It is concluded that PRESS and short TE is useful for quantification of the brain metabolites at 3.0T MRS, our standardized protocol for quantification of the brain metabolites at 3.0T MRS is useful to evaluate the brain diseases by monitoring the systematic changes of biochemical metabolites concentration in vivo.

• Progress in Medical Physics
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• v.18 no.2
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• pp.65-72
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• 2007

An echo planar imaging (EPI)-based spin-echo sequence Is often used to obtain diffusion tensor imaging (DTI) data on most of the clinical MRI systems, However, this sequence is confounded with the susceptibility artifacts, especially on the temporal lobe in the human brain. Therefore, the objective of this study was to design a pulse sequence that relatively immunizes the susceptibility artifacts, but can map diffusion tensor components in a single-shot mode. A multi-slice multi-echo pulsed-gradient spin-echo (MePGSE) sequence with eight echoes wasdeveloped with selective refocusing pulses for all slices to map the full tensor. The first seven echoes in the train were diffusion-weighted allowing for the observation of diffusion in several different directions in a single experiment and the last echo was for crusher of the residual magnetization. All components of diffusion tensor were measured by a single shot experiment. The sequence was applied in diffusive phantoms. The preliminary experimental verification of the sequence was illustrated by measuring the apparent diffusion coefficient (ADC) for tap water and by measuring diffusion tensor components for watermelon. The ADC values in the series of the water phantom were reliable. The MePGSE sequence, therefore, may be useful in human brain studies.

• Transactions of the Korean Society of Mechanical Engineers
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• v.9 no.2
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• pp.135-139
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• 1985

A J$_{IC}$ test procedure by ultrasonic method performed to observe the crack opening behavior of fatigue precrack and detect the initiation of crack propagation of compact tension specimen in this paper. Pulse-echo method with 5 MHz transducer was used on the Cr-Mo steel quenched and tempered at 593.deg. C. We obtained the following results in the elastic-plastic fracture toughness test by ultrasonic method. Echo height is a little increased linearly and rapidly at the early stage of loading . Then it is decreased considerably, finally at the unstable crack growth stage, it is rapidly increased at an unpredictable rae. The initiation of crack propagation is supposed to be at the stage deviated from linearly decreased region and then blunted. J$_{IC}$ value(10.15-12.15 Kgf/mm) by ultrasonic method is lower than that(12.2 Kgf/mm) by R-curve method. But, it is required that the research for the more exact evaluation about correlation between echo height and the crack opening behavior of precrack tip will be continued. continued.ued.

• Investigative Magnetic Resonance Imaging
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• v.13 no.1
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• pp.9-14
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• 2009

T1-, and T2-weighted imagings and FLAIR (fluid attenuated inversion recovery) imaging are fundamental imaging methods in the brain. T1-weighted imaging is a spin-echo sequence with short TR and short TE and produces the tissue contrast by different T1 relaxation times. In other words, short TR maximizes the difference of the longituidinal magnetization recovery between the tissues. T2-weighted imaging is a spin-echo sequence with long TR and long TE and produces the tissue contrast by different T2 relaxation times. Long TE maximizes the difference of the transverse magnetization decay between the tissues. FLAIR is an inversion recovery sequence using 180 degree inversion pulse. 2500 msec of inversion time is applied to suppress the CSF signal.

• Investigative Magnetic Resonance Imaging
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• v.17 no.2
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• pp.133-143
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• 2013

Purpose : To evaluate and compare the accuracy of magnetic resonance imaging (MRI) and ultrasound (US) for detection and estimation of invasion depth of colorectal carcinoma (CRC) by correlation with histopathologic findings in vitro, and to find out the best MR pulse sequence for accurate delineation of tumor from surrounding normal tissue. Materials and Methods: Resected specimens of CRC from 45 patients were examined about tumor detectability and invasion depth of US using high frequency (5-17 MHz) linear transducer in a tube filled with normal saline and MRI in a 8-channel quadrate head coil. The institutional review board approved this study and informed consent was waived. MRI with seven pulse sequences of in- and out-of-phases gradient echo T1 weighted images, fast spin echo T2 weighted image and its fat suppression image, fast imaging employing steady-state acquisition (FIESTA) and its fat suppression image, and diffusion weighted image (DWI) were performed. In each case, both imaging findings of MRI and US were evaluated independently for detection and estimation of invasion depth of tumor by consensus of two radiologists and were compared about diagnostic accuracy according to the histopathologic findings as reference standard. Seven MR pulse sequences were evaluated on the point of accurate delineation of tumor from surrounding normal tissue in each specimen. Results: In specimens of CRC, both imaging modalities of MRI (91.1%) and US (86.7%) showed relatively high diagnostic accuracy to detect tumor and evaluate invasion depth of tumor. In early CRC, diagnostic accuracy of US was 87.5% and that of MRI was 75.0%. There was no statistically significant difference between two imaging modalities (p > 0.05). The best pulse sequence among seven MR sequences for accurate delineation of tumor from surrounding normal tissue in each specimen of CRC was fast spin echo T2 weighted image. Conclusion: MRI and US show relatively high diagnostic accuracy to detect tumor and evaluate invasion depth of resected specimen of CRC. The most excellent pulse sequence of MRI for accurate delineation of tumor from surrounding normal tissue in CRC is fast spin echo T2 weighted image.

• Proceedings of the KOSOMBE Conference
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• v.1992 no.05
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• pp.92-97
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• 1992

The pulsatile nature of blood flow makes artefacts in 2D Fourier transform image. Spatial presaturation is known to be effective in eliminating flow artefacts when the spin echo acquisition is employed. However. this method requires additional RF pulse and spoiling gradient for presaturation. In this paper a new flow saturation technique which does not require additional saturation-RF and gradient is proposed. The proposed technique is equivalent to the existing saturation technique but the elimination of the flow component is achieved by a pair of tailored $90^{\circ}-180^{\circ}$ RF pulses in tile spin echo sequence. By use of two tailored RF pulses with opposite phase polarity, a linear phase gradient is generated for those moving materials and consequently all the spins of moving materials become dephased thereby no signal is observable. Computer simulations and experimental results obtained using both a phantom and a human volunteer with a 2.0 T whole body system are also presented.

• Proceedings of the KOSOMBE Conference
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• v.1997 no.05
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• pp.391-394
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• 1997

In this paper, we considered newly the use of wavelet transform in order to improve the troubles of the established methods for the analysis of ultrasound echo signals. We made the phantoms of 13.2g, 19.8g, 26.4g, 33.0g, 39.8g by ourselves, and extracted the only pulse-echo signals that reflected through the mediums using windowing technique. For determining the characterized value, the signals were wavelet transformed, absoluted, and integral calculated. As the result, we acquired characterized value of each signals, and acknowledged the differences among them except of some datas. But this will be improved by advanced work as sellecting a proper mother wavelet, a method of making phantoms, correcting the various errors, etc. We expect that wavelet transform is powerful for analysis of ultrasound signals.

• Journal of the Korean Society for Precision Engineering
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• v.18 no.9
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• pp.37-44
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• 2001

Ultrasonic testing has a characteristics such as excellent permeability, high-sensitivity to find defect and an almost exact measurement for position. size and direction of inner defect, which differ from other non-destructive testing. In the study, we developed program into optimal testing condition, to distinguish obstacle echo and defect position. This program shows generation and processing of ultrasonic pulse. We compared simulation with ultrasonic test in 45$^\circ$, 60$^\circ$and 70$^\circ$transducer. Test results were in accordance with simulation within 0.1~7.2%.

• The Journal of the Acoustical Society of Korea
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• v.25 no.4E
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• pp.159-165
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• 2006

Human, horse and rat bloods in a cylindrical chamber where flow was controlled by a stirring magnet were used for studying red blood cell aggregation. Ultrasound backscattered powers from blood were obtained from the backscattered signals measured by a 5 MHz focused transducer in a pulse-echo setup. The experimental results showed the differences in red blood cell (RBC) aggregation tendency among the three mammalian species with an order of horse > human > rat. The ultrasound backscattered power decreased with stirring speed in human and horse blood, but no variations were observed in rat blood. Sudden flow stoppage led to the slow increase of the backscattered power for human and horse blood. There was no self-aggregation tendency in rat blood. The enveloped echo images showed the spatial and temporal variations of RBC aggregations in the cylindrical chamber. These observations from the different mammalian species may give a better understanding of the mechanism of RBC aggregation.

• Journal of the Korean Magnetic Resonance Society
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• v.2 no.1
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• pp.59-65
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• 1998

The correction of image artifacts due to misadjustment in tuning of RF coils (tip angle) and in the RF single sideband spectrometer was investigated using phase cycling of the $\pi$/2 and $\pi$ pulses in spin-echo sequences. A general procedure was developed for the systematic design of phase cycles that select desirable coherence transfer pathways. To analyze a phase cycling sequence, changes in the coherence level and phase factor for each RF pulse in the spin-echo cycle must be determined. Four different phase cycling schemes (FIXED, ALTERNATE, FORWARD, REVERSED) to suppress unwanted signal components such as mirror and ghost images were evaluated using two signal acquisitions. When the receiver phase factor is cycled counter-clockwise (REVERSED), these artifacts are completely removed.