• Journal of Korean Academy of Nursing
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• v.46 no.4
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• pp.514-522
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• 2016

Purpose: The purpose of this study was to identify the effects of exhalation breathing exercises using expirometer and that of inhalation breathing exercises using incentive spirometry on pulmonary function and complications in elderly patients with upper-abdominal surgery. Methods: The research design was a nonequivalent control group non-synchronized design. Participants were 63 patients who underwent upper-abdominal surgery under general anesthesia (32 in experiment group, 31 in control group). They were recruited at P university hospital from August 1 to November 30, 2015. Effects were evaluated by measuring pulmonary functions (Forced Vital Capacity [FVC], Forced Expiratory Volume in 1 second [FEV1]) and pulmonary complications. Data were analyzed using SPSS/WIN 18.0 program. Results: There was no difference in FVC between the experimental group and the control group, but FEV1 in the experimental group increased significantly compared to the control group by time change (p=.001). Also, there were no pulmonary complications in the experimental group but there were 5 cases (16.1%)(p=.018) in the control group. Conclusion: Findings indicate that exhalation breathing exercises by elderly patients following upper-abdominal surgery is an effective nursing intervention in enhancing pulmonary function and preventing pulmonary complications.

• Journal of the Korean Society of Physical Medicine
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• v.5 no.4
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• pp.597-604
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• 2010

Purpose : This study investigated the effects of air stacking exercise on respiratory ability of patients with cervical cord injury. Methods : The subjects of this study were 30 patients with cervical cord injury were randomly placed in an experimental group(n=15) and a control group(n=15), respectively. Basic therapeutic exercise(ROM exercise, stretching exercise, strengthening exercise) were conducted twice a day for 30 minutes each time in all subjects and air stacking exercise was additionally conducted on the experimently group only. Air stacking exercise was conducted for 4 weeks, twice a day, 5 times a week and repeated 10 to 15 times each time. Lung capacity, MIC and, peak cough flow were measured and evaluated. Results : The results showed that FEV1, FVC, MIC, UPCF and APCF were significantly increased(p<.05), but FEV1/FVC didn't show the significant differences in an experimental group. In a control group, the findings showed that FEV1, FVC were increased significantly(p<.05) while FEV1/FVC, MIC, UPCF, and APCF didn't show the significant differences.There were significant differences in FEV1, FVC, MIC, and APCF between a experimental group and a control group in the results of Pulmonary Function Test after conducting the pulmonary rehabilitation. However, no significant differences were found in FEV1/FVC, and UPCF between a experimental and a control group(p>.05). Conclusion : air stacking exercise has positive effects on the improvements of cough functions and that of pulmonary functions such as lung volume, lung elasticity in patients with cervical cord injury.

• Tuberculosis and Respiratory Diseases
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• v.85 no.2
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• pp.137-146
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• 2022

Background: Farinelli breathing (FB) exercise is a typical breathing exercise used by singers. This study aimed to compare effects of FB exercise and diaphragmatic breathing (DB) exercise on respiratory function and symptoms in patients with chronic obstructive pulmonary disease (COPD). Methods: Sixteen patients aged 51-80 years with mild or moderate COPD were recruited for this study. They were divided into two groups: DB group (n=8) and FB group (n=8). Both groups received complete breathing exercise training five times per week for 8 weeks. Their respiratory functions, COPD symptoms, cytokine levels, and oxidative stress variables were analyzed during pre- and post-tests. Dependent variables were compared between pre- and post-tests using paired t-tests. An independent t-test was used to compare variables between the groups. Differences were considered significant at p<0.05. Results: The maximal expiratory pressure (MEP), maximum oxygen consumption (VO₂max), and COPD Assessment Test (CAT) scores changed significantly in the DB group after the 8-week intervention compared to those at pre-test, whereas force vital capacity, forced expiratory volume in the first second, maximum voluntary ventilation, maximal inspiratory pressure (MIP), MEP, VO₂max, CAT score, tumor necrosis factor-α, and malondialdehyde level changed significantly in the FB group at post-test compared to those at pre-test. Moreover, both MIP and MEP in the FB group were significantly higher than those in the DB group. Conclusion: FB exercise improved respiratory functions and COPD symptoms of patients with COPD. It might be an alternative breathing exercise in pulmonary rehabilitation programs for patients with COPD.

• The Journal of Korean Physical Therapy
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• v.24 no.5
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• pp.355-361
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• 2012

Purpose: The purpose of this study was to evaluate the effectiveness of pulmonary rehabilitation on lung function and fatigue in persons with chronic obstructive pulmonary disease (COPD). Methods: Thirty one persons with COPD participated in this study. Four groups were allocated as follows: experimental group 1 (under 10 years of the post-disease period), control group 1 (under 10 years of the post-disease period), experimental group 2 (over 10 years of the post-disease period), and control group 2 (over 10 years of the post-disease period). Results: Forced expired volume in one second (FEV1) % pred and lactic acid showed improvement in experimental group 1 and experimental group 2 after training. Control group 1 and control group 2 did not show improvement of FEV1% pred and lactic acid after training. However, FEV1% pred and lactic acid in experimental group 1 were not significantly different, compared with the experimental group. Conclusion: Results of our study suggest that implementation of a pulmonary rehabilitation program resulted in improvement of lung function and fatigue in persons with COPD not related to the post-disease period.

• Journal of the Korean Society of Physical Medicine
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• v.14 no.1
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• pp.43-51
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• 2019

PURPOSE: To prevent secondary complications from decreased pulmonary functions and promote neurological recovery, identification of respiratory capacity change patterns depending on different postures of stroke patients and investigation of their properties are needed for active rehabilitation. Therefore, this study was conducted to investigate the changes in vital capacity in response to different positions and to implement the results as clinical data. METHODS: A respiratory function test was administered to 52 patients with stroke in the sitting, supine, paretic side lying, and non-paretic side lying positions. Pulmonary function indexes used for comparison were forced vital capacity (FVC), forced expiratory volume at 1 second (FEV1), forced expiratory flow 25-75% (FEF 25-75%), and maximum voluntary ventilation (MVV). One-way repeated ANOVA was used for analysis, and post hoc analysis was conducted using least significant difference (LSD). RESULTS: All pulmonary function indexes were measured in the order of sitting, paretic side lying, supine, and non-paretic side lying positions. Excluding the FEF25-75% and MVV of the supine compared with the paretic side lying position, all other pulmonary function indexes differed significantly (p<.05). CONCLUSION: There are differences in pulmonary function indexes depending on different postures of stroke patients, and the study showed that the non-paretic side lying position yielded the greatest effect on lung ventilation mechanisms. Based on these results, appropriate postures need to be considered during physical therapy interventions for stroke patients.

• The Journal of Korean Physical Therapy
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• v.34 no.5
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• pp.248-254
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• 2022

Purpose: This study was undertaken to identify the effect of amateur wind musical performance and choir activity on pulmonary function, and to determine the usefulness as a respiration training program by measuring the pulmonary functions of subjects. Methods: A total of 90 subjects (wind instrument players group=30, choir members group=30, control group=30) participated in the experiment. Pulmonary function test (FVC, FEV₁, FEV₁/FVC ratio, MVV, SVC, PEF, FEF 25-75%, IRV, ERV) was conducted using a spirometer (CardioTouch 3000S, Bionet, Seoul, Republic of Korea). Each factor was measured 3 times to meet the American Thoracic Society criteria, and the highest value was used in the analysis. Results: Comparing pulmonary function between the amateur wind instrument players (WP), amateur choir members (CH), and control (CG) groups revealed significant differences in FEV₁, FVC, FEV₁/FVC, and ERV (p<0.05). Highest values were obtained in the WP group. Significant differences were obtained for various factors in the multiple regression analysis of practice year (PY), practice time per week (PTPW), and exercise time per week (ETPW): FEV₁ and FVC in PY, FEV₁/FVC in PTPW, and FEV₁/FVC, MVV, PEF, and FEF (25-75%) in ETPW. Conclusion: Amateur wind instrument performance effectively improves lung function and is useful as a breathing training program for preventing debilitation and improving respiratory function.

• BMB Reports
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• v.57 no.3
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• pp.143-148
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• 2024

Pulmonary fibrosis is a serious lung disease that occurs predominantly in men. Genistein is an important natural soybean-derived phytoestrogen that affects various biological functions, such as cell migration and fibrosis. However, the antifibrotic effects of genistein on pulmonary fibrosis are largely unknown. The antifibrotic effects of genistein were evaluated using in vitro and in vivo models of lung fibrosis. Proteomic data were analyzed using nano-LC-ESI-MS/MS. Genistein significantly reduced transforming growth factor (TGF)-β1-induced expression of collagen type I and α-smooth muscle actin (SMA) in MRC-5 cells and primary fibroblasts from patients with idiopathic pulmonary fibrosis (IPF). Genistein also reduced TGF-β1-induced expression of p-Smad2/3 and p-p38 MAPK in fibroblast models. Comprehensive protein analysis confirmed that genistein exerted an anti-fibrotic effect by regulating various molecular mechanisms, such as unfolded protein response, epithelial mesenchymal transition (EMT), mammalian target of rapamycin complex 1 (mTORC1) signaling, cell death, and several metabolic pathways. Genistein was also found to decrease hydroxyproline levels in the lungs of BLM-treated mice. Genistein exerted an anti-fibrotic effect by preventing fibroblast activation, suggesting that genistein could be developed as a pharmacological agent for the prevention and treatment of pulmonary fibrosis.

• The Korean Journal of Physiology
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• v.11 no.2
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• pp.41-43
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• 1977

In pulmonary function which is important place which national physical power, in maximal grade of physical power, and end growth and development whom aged 20 years old that whole members 74 students, and taken pulmonary functions examination records, and took as the following results. 1) Frequency of breathing: Pertaining of the frequency of breathing are about form 15, to 16 times per minute at male and female students. 2) Vital capacity: Measures of vital capacity are in case of male students, whom was about 4.3 liter, and female students was about 3.6, liter which different between male and female students was more low quantity at female students with comparison male students. 3) Tidal volume: Pertaining of the volume are in case of male students, whom was 521ml, and female students was 497m1, and was slightly low quantity at female students with comparison male students, 4) Breathing holding time: Breathing holding time are in case of male students, whom was 64 sec, and female students was 55 sec, and was sbout 10 sec more high quantity at male students than female students.

• Asian-Australasian Journal of Animal Sciences
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• v.10 no.3
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• pp.318-323
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• 1997

In order to assess the effect of solar exposure on pulmonary functions and evaporative losses from skin and pulmonary surfaces, in six healthy Sahiwal (S) and six Sahiwal ${\times}$ Holstein ($S{\times}H$) cattle were exposed to direct sun during summer. Breed differences were observed during exposure. Increase in sweating rate was higher in crossbreds (222%) than in Sahiwal (125%). Pre-exposure (ambient temperature, $32.6{\pm}0.85^\circ}C$, solar radiation, $0.9cal\;cm^{-2}min^{-1}$) evaporative loss from skin accounted for about 90% of the losses and remaining losses were contributed by pulmonary surfaces in Sahiwal. The contribution of evaporation through skin increased to 92% (ambient temperature $39.4{\pm}0.68^\circ}C$, solar radiation, $1.35cal\;cm^{-2}min^{-1}$). In crossbreds 80% of the evaporative losses were through skin before exposure which increased to 87% after exposure to solar radiations. Rectal temperature increase was higher in crossbreds ($1.5^{\circ}C$) than in Sahiwal ($0.8^{\circ}C$). With the increase in pulmonary evaporative losses, respiratory frequency increased to 2 fold in Sahiwal and pulmonary ventilation increased 1.6 times the resting value in Sahiwal due to solar exposure. In $S{\times}H$ crossbreds the respiratory frequency increased 3.5 times and pulmonary ventilation increased only to 1.8 times due to decrease in tidal volume. There was about 2 fold increase in alveolar ventilation in both the breeds, the increase in dead space ventilation was more in crossbreds than in Sahiwal. Behavioral symptoms exhibited by animals after exposure were profuse salivation, open mouth panting, tongue protrusion and general restlessness.

• Physical Therapy Korea
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• v.22 no.4
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• pp.34-43
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• 2015

The purpose of this study was to compare the effects of underwater treadmill gait training (UTGT) and overground treadmill gait training (OTGT) on the gait, balance ability and pulmonary function of stroke patients. Twenty subjects were recruited for this study. The subjects were randomly assigned to two groups: UTGT ($n_1$=10) and OTGT ($n_2$=10). The 10 m walk test (10 MWT), Berg Balance Scale, Timed Up and Go (TUG) test, center of pressure, pulmonary function of forced vital capacity (FVC), forced expiratory volume after 1 sec (FEV1) and FEV1/FVC were measured before and after 4 weeks of training. Both groups undertook the gait training for 30 min a day, 3 times a week, for 4 weeks, and rating of perceived exertion of the groups were measured and compared. All the studied variables were significantly improved in both groups (p<.05) at the end of the study, except in the FEV1 of OTGT (p>.05). There was significant between-group difference in all of the variables, except in the 10 MWT (p>.05). These findings suggest that UTGT is more effective than OTGT in improving the balance and pulmonary functions of stroke patients.