• Tuberculosis and Respiratory Diseases
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• v.84 no.1
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• pp.74-83
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• 2021

Background: This study compared the treatment outcomes of patients with multidrug-resistant tuberculosis (MDR-TB) before and after the implementation of public-private mix (PPM). Factors affecting treatment success were also investigated. Methods: Data from culture-confirmed pulmonary MDR-TB patients who commenced MDR-TB treatment at Pusan National University Hospital between January 2003 and December 2017 were retrospectively reviewed. Patients were divided into two groups in terms of PPM status: pre-PPM period, patients who commenced MDR-TB treatment between 2003 and 2010; and post-PPM period, patients treated between 2011 and 2017. Results: A total of 176 patients were included (64 and 112 in the pre- and post-PPM periods, respectively). 36.9% of the patients were resistant to a fluoroquinolone or a second-line injectable drug, or both. The overall treatment success rate was 72.7%. The success rate of post-PPM patients was higher than that of pre-PPM patients (79.5% vs. 60.9%, p=0.008). Also, loss to follow-up was lower in the post-PPM period (5.4% vs. 15.6%, p=0.023). In multivariate regression analysis, age ≥65 years, body mass index ≤18.5 kg/m², previous TB treatment, bilateral lung involvement, and extensively drug-resistant (XDR)- or pre-XDR-TB were associated with poorer treatment outcomes. However, the use of bedaquiline or delamanid for ≥1 month increased the treatment success. Conclusion: The treatment success rate in MDR-TB patients was higher in the post-PPM period than in the pre-PPM period, particularly because of the low rate of loss to follow-up. To ensure comprehensive patient-centered PPM in South Korea, investment and other support must be adequate.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.25 no.1
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• pp.70-78
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• 2022

Purpose: Cholestasis resulting from cytomegalovirus (CMV)-induced hepatitis manifests in 40% of patients with a CMV infection. Ganciclovir treatment in children with CMV infections has proven to be highly effective. Until now, there are very few studies have identified predictive factors for liver biochemistry improvement after ganciclovir therapy. This study aimed to identify the predictors of liver biochemistry improvement in patients with CMV cholestasis after ganciclovir treatment. Methods: A retrospective cohort study was conducted using medical records from Dr. Sardjito General Hospital Yogyakarta, Indonesia from 2013 to 2018. CMV cholestasis was confirmed based on serum CMV IgG and IgM positivity and/or blood and urine CMV antigenemia positivity. Incomplete medical records and other etiologies for cholestasis, such as biliary atresia, choledochal cyst, metabolic diseases, and Alagille syndrome, were excluded. Patient age at cholestasis diagnosis and ganciclovir treatment, duration of CMV cholestasis, history of prematurity, central nervous system involvement, and nutritional status were analyzed and presented as an odds ratio (OR) with a 95% confidence interval (95% CI). Results: CMV cholestasis with ganciclovir therapy was found in 41 of 54 patients. Multivariate analysis showed that a shorter duration of CMV cholestasis (OR: 4.6, 95% CI: 1.00-21.07, p=0.04) was statistically significant for liver biochemistry improvement after 1 month of ganciclovir treatment. The remaining factors that were analyzed were not significant predictors of liver biochemistry improvement in patients with CMV cholestasis after ganciclovir treatment. Conclusion: A shorter duration of CMV cholestasis is the predictor of liver biochemistry improvement after 1 month gancyclovir treatment.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.9
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• pp.4427-4430
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• 2012

Breast cancer is the most common cancer and the leading cause of cancer death among women in Malaysia. Despite the campaigns undertaken to raise the awareness of the public regarding breast cancer, breast cancer screening rates are still low in the country. The community pharmacist, as one of the most accessible healthcare practitioners, could play a role in the provision of breast cancer health promotion services to the community. However, there are no documented data regarding the community pharmacists' involvement in breast cancer related health promotion activities. Hence, this study was conducted to examine self-reported knowledge, practice and perception of community pharmacists on provision of breast cancer health promotion services and to investigate the barriers that limit their involvement. This cross-sectional survey conducted between May to September 2010, included a sample of 35 community pharmacists working in the districts of Hulu Langat and Sepang in state of Selangor. A 22-item validated questionnaire that included both closed and Lickert scale questions was used to interview those pharmacists who gave their informed consent to participate in the study. The data was analysed using SPSS. Only 11.3% of the community pharmacists answered all the questions on the knowledge section correctly. The mean overall knowledge of the community pharmacists on risk factors of breast cancer and screening recommendations is 56%. None of the respondents was currently involved in breast cancer health promotion activities. Lack of time (80%), lack of breast cancer educational materials (77.1%) and lack of training (62.9%) were the top three mentioned barriers. Despite these barriers, 94.3% (33) of the community pharmacists agreed that they should be involved in breast cancer health promotion activities. Hence, there is need to equip community pharmacists with necessary training and knowledge to enable them to contribute their share towards prevention and screening of breast cancer.

• Journal of Korean Neurosurgical Society
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• v.61 no.2
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• pp.258-266
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• 2018

Objective : The diagnosis of insufficiency fractures of the sacrum in an elder population increases annually. Fractures show very different morphology. We aimed to classify sacral insufficiency fractures according to the position of cortical break and possible need for intervention. Methods : Between January 1, 2008 and December 31, 2014, all patients with a proven fracture of the sacrum following a low-energy or an even unnoticed trauma were prospectively registered : 117 females and 13 males. All patients had a computer tomography of the pelvic ring, two patients had a magnetic resonance imaging additionally : localization and involvement of the fracture lines into the sacroiliac joint, neural foramina or the spinal canal were identified. Results : Patients were aged between 46 and 98 years (mean, 79.8 years). Seventy-seven patients had an unilateral fracture of the sacral ala, 41 bilateral ala fractures and 12 patients showed a fracture of the sacral corpus : a total of 171 fractures were analyzed. The first group A included fractures of the sacral ala which were assessed to have no or less mechanical importance (n=53) : fractures with no cortical disruption ("bone bruise") (A1; n=2), cortical deformation of the anterior cortical bone (A2; n=4), and fracture of the anterolateral rim of ala (A3; n=47). Complete fractures of the sacral ala (B; n=106) : parallel to the sacroiliac joint (B1; n=63), into the sacroiliac joint (B2; n=19), and involvement of the sacral foramina respectively the spinal canal (B3; n=24). Central fractures involving the sacral corpus (C; n=12) : fracture limited to the corpus or finishing into one ala (C1; n=3), unidirectional including the neural foramina or the spinal canal or both (C2; n=2), and horizontal fractures of the corpus with bilateral sagittal completion (C3; n=8). Sixty-eight fractures proceeded into the sacroiliac joint, 34 fractures showed an injury of foramina or canal. Conclusion : The new classification allowes the differentiation of fractures of less mechanical importance and a risk assessment for possible polymethyl methacrylate leaks during sacroplasty in the direction of the neurological structures. In addition, identification of instable fractures in need for laminectomy and surgical stabilization is possible.

• Information Systems Review
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• v.9 no.3
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• pp.133-156
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• 2007

The wide spread of the Internet and personal computers does not only alter the form of content from analog to digital, but also lead to the emergence of a new digital media system that is different from analog media system. The digital media system is a convergent media that includes both public and private systems from the perspective of use-limitation, as well as storage and enjoyment systems from the perspective of use-purpose. The major goal of this research is to suggest and empirically verify an effective way of presenting the perception of places that are converged in the digital media system. Involvement and motivation are suggested as key conceptual factors and color contrast and hue are suggested as concrete design factors to make people perceive corresponding places. Results of our controlled experiment indicated that the color contrast and hue significantly affected the perception of place, and consequently, influenced usability of the digital media system. This paper ends with implications that can be used to construct appropriate perception of places for the media system of digital products.

• Journal of Families and Better Life
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• v.15 no.3
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• pp.45-58
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• 1997

The purpose of this study was to investigate the relationship between the maternal child rearing behaviors and home environmental variables related with children's self-esteem in urban and rural community. Subjects were 435 boys and girls enrolled in grade 4, 5, 6 and their mothers from five public elementary schools in Chonan city and Naju city. The instruments for the study were coopersmith's Self Esteem Inventory Korean Maternal Behavior Inventory and questionnaire on home environmental variables. The data were analyzed by Pearson's one-way ANOVA t-test and Duncan post hoc test. The major findings were as follows: 1. Children's self esteem and 'Affection' and 'Achievement' of maternal child rearing behaviors were a positive correlation. 2. Children's self esteem of urban community was higher than that of rural community. Maternal child rearing behaviors of urban community was 'Achievement' of maternal child rearing behaviors were a positive correlation. 2. Children's self e teem of urban community was higher than that of rural community. Maternal child rearing behaviors of urban community was 'Active Involvement' and that of rural community were 'Authoritaran Control', 'Overprotection' and 'Achievement' 3. There were no differences in children's self esteem with family size. 4. There were significant differences in children's self esteem with parent's educational leveland monthly family income; the higher parent's educational level and the more monthly family income the higher children's self-esteem. 5. There were also significant differences in maternal child rearing behaviors 5. There were also significant differences in maternal child rearing behaviors with 'Achievement' by parent's age monthly family income and family size in 'Reasoning Guidance' and 'Active Involvement' by parent's educational level. in 'Authoritarian Control' and 'Overprotection' by monthly family income and in 'Reasoning Guidance' and 'Authoritarian Control' by family size.

• Management & Information Systems Review
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• v.24
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• pp.97-124
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• 2008

This study aimed to explore how the involvement of environment influenced eight subjects group. Thus, experiment was performed to clarify the role that the attitude of university student consumer plays in the communication process depending on the level of engagement of consumer in the environment and method to raise donation for preservation of environment. Analyzing as per the type of appeal, the mark in altruistic appeal type was higher in all variables than egoistic appeal type. Finally, checking the average mark of each variable as per the condition of donation, the value in unconditional donation was higher than in all variables than conditional donation. It was found 3 groups composed of 2 groups with high level of environmental engagement and 1 group with low level of environmental engagement were suitable to double mediation model among the 8 experimental groups. The group where double mediation model best corresponds than any other group was high level related to environment and the group that contacts altruistic appeal and the message in the form of conditional donation. It was also found that the group that has low level of environmental engagement and contacts egoistic appeal type and conditional donation shows the group that corresponds to double mediation model in the second place among the 8 groups. Finally, it was found that the group that has high level of environmental engagement and is stimulated by altruistic appeal and unconditional donation corresponds to double mediation model. Depending on the condition of message stimulation, unconditional donation is found to better correspond to double mediation model than conditional donation. However, opposite phenomena is observed when the level of environmental engagement is high and appeal type is egoistic. Namely, it was found that conditional donation better corresponds to double mediation model than unconditional donation.

• Journal of Families and Better Life
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• v.22 no.1
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• pp.11-25
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• 2004

This study was conducted to explore the impacts of involvement in the Vietnam War on the self-esteem of the veterans in their later lives. In this study, 14 Korean male Vietnam War veterans from 55 to 63 years old were asked about the impacts of their war experiences on their self-esteem. From the analysis of the in-depth interviews the following conclusions were drawn: First, the veterans perceived that their self-esteem improved with both internal and external impacts of their activities in Vietnam. The internal aspects that improved the veterans' self-esteem were recalling their positive memories of Vietnam War, such as being on duty at a war front for the sake of our country, doing volunteer work for the villagers, and becoming a masculine heroic figure in the family legend. The external aspects were positive attitudes and responses toward their war activities from their family, friends, and neighbors. Second, they also felt persistently frustrated with their recurring memories of involvement in killing human beings, experiences of negative family and social responses, and the side effects of herbicidal cyanide they suffer. In this article, the following suggestions were made. First, standardized images and good-will episodes of the Vietnam War need to be provided by the government, in order to improve public images on the veterans. Second, intensive adjustment programs for the families of older veterans in special needs should be developed in collaboration with various veterans' societies and family counseling institutions, so that the spouses and children can be relieved from tension-laden contacts with the veterans and prevent violent incidents.

• Journal of Korean Society of Transportation
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• v.19 no.6
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• pp.49-63
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• 2001

The pattern of urban transport activity has two major components: the movement of people and the movement of goods. Roads in urban areas carry large number of trucks laden with goods that support urban economy and lifestyle. Therefore urban goods movement plays a vital role, but at the same time, urban goods movement are an important source of congestion, and a major contributor to the adverse environmental and social impacts of urban transport. In addition, the demand for goods movement is growing at a faster rate than personal travel in many cities, due to changes in industry logistics and consumer purchasing patterns. As a result, the significance of urban freight activity is increasing in terms of both its role in urban economy and its adverse impacts on urban amenity. This study is focused on the role and involvement scope of metropolitan government in urban logistics aimed at increasing its efficiency and reducing its negative impacts. The major suggestions of this study are (a) development of a measure of urban goods movement activity, (b) evaluation of data requirements and availability, (c) dialogue between the public sector and private sector, and (d) the role of metropolitan government.

• Safety and Health at Work
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• v.10 no.1
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• pp.95-102
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• 2019

Background: In a cluster-randomized trial, the Safety and Health Involvement For Truck drivers intervention produced statistically significant and medically meaningful weight loss at 6 months (-3.31 kg between-group difference). The current manuscript evaluates the relative impact of intervention components on study outcomes among participants in the intervention condition who reported for a post-intervention health assessment (n = 134) to encourage the adoption of effective tactics and inform future replications, tailoring, and enhancements. Methods: The Safety and Health Involvement For Truck drivers intervention was implemented in a Web-based computer and smartphone-accessible format and included a group weight loss competition and body weight and behavioral self-monitoring with feedback, computer-based training, and motivational interviewing. Indices were calculated to reflect engagement patterns for these components, and generalized linear models quantified predictive relationships between participation in intervention components and outcomes. Results: Participants who completed the full program-defined dose of the intervention had significantly greater weight loss than those who did not. Behavioral self-monitoring, computer-based training, and health coaching were significant predictors of dietary changes, whereas behavioral and body weight self-monitoring was the only significant predictor of changes in physical activity. Behavioral and body weight self-monitoring was the strongest predictor of weight loss. Conclusion: Web-based self-monitoring of body weight and health behaviors was a particularly impactful tactic in our mobile health intervention. Findings advance the science of behavior change in mobile health intervention delivery and inform the development of health programs for dispersed populations.