• Toxicological Research
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• v.23 no.4
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• pp.301-309
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• 2007

Paecilomyces tenuipes (PT), one of the Ascomycetes family, has been used for medicinal purposes due to its broad pharmacological activities. The present study was undertaken to investigate the hepatoprotective effects of PT water extracts against $CCl_4$-induced hepatotoxicity in primary cultures of adult rat hepatocytes. When the extract of PT was directly added into the culture medium at 1, 2, and 5 mg/ml, the extracts not only reduce the $CCl_4$-induced elevation of aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase, and lipid peroxide, but also protect cultured hepatocytes from $CCl_4$-induced reduction of reduced glutathione, glutathione reductase, glutathione-S-transferase, glutathione peroxidase, catalase and superoxide dismutase. In addition, the effects of PT water extracts on cytochrome P450 enzymes were relatively marginal, indicating that the hepatoprotective effects of PT extract against $CCl_4$-induced toxicity might not be due to the inhibition of $CCl_4$ activation. In conclusion, the PT extracts were effective in protecting against $CCl_4$ induced hepatotoxicity in hepatocyte cultures, at least in part, by scavenging free radicals, and by modulating enzyme systems involved in cellular oxidative stress.

• 한국생물공학회:학술대회논문집
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• 2003.04a
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• pp.428-432
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• 2003

In this study, we demonstrated that high cell density for Thiobacillus ferrooxidans could be obtained when optimal conditions for cell growth were maintained using electrochemical cultivation with sufficient aeration. The optimal pH for cultivation were determined to be $2.0{\pm}0.05$. When the current and potential were set to 0.15A, 4V, the Pt electrode reduced $Fe^{3+}$ to $Fe^{2+}$ with efficiency of 85%. Under these condition, cells at an initial density of 0.0025 g-dry cell/L grew for 8days until the cell density was 0.0576 g-dry cell/L. this was a 7-fold increase over conventional batch culture.

• Proceedings of the Korean Magnestics Society Conference
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• 2007.05a
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• pp.126.2-126.2
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• 2007

• Archives of Plastic Surgery
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• v.51 no.2
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• pp.163-168
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• 2024

Background The study determined to compare the clinical outcomes of traditional gold weight implantation for the correction of paralytic lagophthalmos with those of a newly designed model. Methods In this retrospective cohort study, we enrolled 30 patients (76% females; average age 60.8 ± 12 years) with facial palsy who underwent implantation of either the traditional pretarsal gold weight (PT group; n = 15) or a new supratarsal model (ST group; n = 15) from May 2014 to April 2019. The main outcome measures were the 12-month postoperative weight prominence, weight migration, improvement of lagophthalmos, upper eyelid contour, and upper eyelid ptosis. The secondary outcome was long-term (24 months) reoperative rate. Results The new model group had significantly better eyelid contour (risk ratio [RR] 3.16, 95% confidence interval [CI] 1.62-6.15, p = 0.001), less weight prominence (RR 1.74, 95% CI 1.13-2.70, p = 0.013), less weight migration (RR 1.31, 95% CI 1.12-1.54, p = 0.001), and less eyelid ptosis (RR 2.36, 95% CI 1.21-4.59, p = 0.011) than the traditional model group. Improvement of lagophthalmos was not statistically significant between the two groups (RR 1.44, 95% CI 0.72-2.91, p = 0.303). The 24-month reoperative rate was 53.3% in the PT group versus 13.3% in the ST group (RR 2.00, 95% CI 1.15-3.49, p = 0.015). Conclusion The newly designed supratarsal gold weight showed superior postoperative outcomes than the standard traditional model.

• Child Health Nursing Research
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• v.5 no.2
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• pp.125-135
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• 1999

The purpose of this study was to identity the level of burden and quality of life of the subjects. The subjects of this study were 68 mothers of nephrotic syndrome patients who children hospitalized in 2 Pediatric wards of University Hospital in Seoul. The data were collected through a questionnaires and the period of the data collection was from August 1st to September 30th ,1998. The instruments for this study were Burden Measurement Instrument developed by Montgomery et. al (1985) and Quality of life scale designed by Ro, Yoo JA(1988). The statistical analysis was used by SPSS, t-test, ANOVA and Pearson correlation coefficient. The results of were as follows. : 1. The level of burden showed a mean score 54.47 and the level quality of life, a mean score 140.20. 2. The level of burden differed according to s religion, pt's purpose of admission and perceived patient's condition by mothers. 3. The level of quality of life differed according to perceived pt's condition by mothers. 4. There was a negative correlation between burden and quality of lifer =-3.97, p<.001).

• Proceedings of the KIEE Conference
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• 2002.11a
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• pp.22-24
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• 2002

지금까지 변전소나 개폐소에서 전류, 전압을 계측하는 수단으로서 주로 철심과 권선으로 구성되어진 변류기(CT), 계기용 변압기(PT, PD)가 사용되어져 왔다. 최근, 2차측의 계측기나 보호 Relay의 Digital화가 진전되어, 또한 이것을 Digital Network으로 총합한 Intelligent 변전소의 구축이 검토되어짐에 따라, Digital Network에 대응한 신형 CT, VD가 요구되어지고 있다. 상기와 같은 요구로 인해 당사에서는 CT는 검출부에 Rogowski Coil을 적용하며 그 후단에 적분기를 설치하였으며, VD는 검출부에 중간 전극을 이용해서 분압하는 방식인 Capacitive Voltage Divider를 사용하고 증폭기를 삽입하여, 각각 요구되는 전압 신호를 얻었다. 이러한 신형 CT/VD의 적용으로 종래의 CT/PT가 차지하는 공간이 필요 없게 되어 컴팩트한 GIS의 구조가 가능하게 되어 있다.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2002.11a
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• pp.163-166
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• 2002

We investigated structural and electrical properties of Metal-Oxide-Semiconductor(MOS) structure using Hafnium $oxide(HfO_{2})$ as high-k gate dielectric material. $HfO_{2}$ films are ultrathin gate dielectric material witch have a thickness less than 2.0nm， so it is spotlighted to be substituted $SiO_{2}$ as gate dielectric material. In this paper We have grown $HfO_{2}$ films with pt electrode on P-type Silicon substrate by RF magnetron sputtering system using $HfO_{2}$ target and oserved the property of semiconductor-oxide interface. Using pt electrode, it is necessary to be annealed at ${300^{\circ}C}$. This process is to increase an adhesion ratio between $HfO_{2}$ films with pt electrode. In film deposition process, the deposition time of $HfO_{2}$ films is an important parameter. Structura1 properties are invetigated by AES depth profile, and electrical properties by Capacitance-Voltage characteristic. Interface trap density are measured to observe the interface between $HfO_{2}$ with Si using High-frequency(1MHz) C-V and Quasi - static C-V characteristic.

• Proceedings of the KIEE Conference
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• 2002.11a
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• pp.16-18
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• 2002

We attempted to fabricate a dendrimer Langmuir-Blodgett(LB) films containing 48 pyridinepropanol functional end group. As the pyridinepropanol functional group could form a complex structure with metal ions. In this study the samples for electrical measurement were fabricated to two types metal complexes with $Pt^{4+}$ and $Fe^{2+}$ ions by LB method. And we have investigated the surface activity at the air-water interface as well as the electrical properties for the monolayers of pure G4-48PyP dendrimer and its complex with metal ions($Pt^{4+}$ and $Fe^{2+}$ ions). In the surface pressure-area($\pi-A$) isotherms of the dendrimers, the stable condensed films formed at the air-water interface and the metal ions effect showed the difference on molecular behavior. We have studied the electrical properties of the ultra thin dendrimer LB films investigated by the current-voltage(I-V) characteristics of metal/dendrimer LB films/metal(MIM) structure. In conclusion, it is demonstrated that the metal ion around G4-48PyP dendrimer can contribute to make formation of network structure among dendrimers and it result from the change of electrical properties.

• Korean Journal of Plant Resources
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• v.28 no.2
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• pp.279-289
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• 2015

Genetic diversity and genetic differentiation of thirteen Pinus densiflora populations in South Korea were estimated using nine ESTP (Expressed Sequence Tag Polymorphism) markers. The numbers of allele and the effective allele were 2.2 and 1.8, respectively. The percentage of polymorphic loci (P) was 98.8%. The observed and the expected heterozygosity were 0.391 and 0.402, respectively, and the eleven populations except for Ahngang and Gangneung population were under Hardy-Weinberg equilibrium state. The level of genetic differentiation (Wright’s F_ST = 0.057) was higher than those of isozyme or nSSR markers. We could not find out any relationship between the genetic distance and geographic distribution among populations from cluster analysis. Also, the genetic differentiation between populations was not correlated with the geographic distance (r = 0.017 and P = 0.344 from Mantel test). From the result of F_ST-outlier analysis to identify a locus under selection, six loci were detected at confidence interval of 99% by the frequentist’s method. However, only three loci (sams2+AluⅠ, sams2+RsaⅠ, PtNCS_p14A9+HaeⅢ) were presumed as outliers by Bayesian method. The sams2+AluⅠ and sams2+RsaⅠlocus were originated from the sams2 gene and seemed to be the loci under balancing selection.

• Applied Biological Chemistry
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• v.30 no.2
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• pp.186-191
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• 1987

Relationship between the contents of ginsenosides in root and minerals (N,P,K,Ca,Mg) in leaf and root of and year Panax ginseng grown with solutions of various N,P,K levels was investigated by simple, multiple and partial regressions. In root K, N, and P in decreasing order showed significant negative correlation with each ginsenosides. In leaf K,N, and P in decreasing order showed significant positive, negative and both correlation with root ginsenosides, respectively. Relationship between K and root ginsenosides in the minus K plot did not follow that in other plots. The ratios of K,N, and P, in leaf to root in decreasing order showed positive correlations that were greater than in leaf or root. Mg was negatively while Ca was positively correlated in root but these were reverse in leaf and always nonisgnificant in both parts. Ginsenoside Rd, Re and $Rb_1$ were most affected by mineral contents. The effect of minerals on PT/PD was least.