• Title/Summary/Keyword: Protocol-Based Approach

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A complete integrity assessment of welded connections under high and low cycle fatigue followed by fracture failure

  • Feng, Liuyang;Liu, Tianyao;Qian, Xudong;Chen, Cheng
    • Steel and Composite Structures
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    • v.43 no.4
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    • pp.465-481
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    • 2022
  • This paper presents a comprehensive integrity assessment of welded structural components, including uniform high- and low-cycle fatigue assessment of welded plate joints and fatigue-induced fracture assessment of welded plate joints. This study reports a series of fatigue and fracture tests of welded plate joints under three-point bending. To unify the assessment protocol for high- and low-cycle fatigue of welded plate joints, this study develops a numerical damage assessment framework for both high- and low-cycle fatigue. The calibrated damage material parameters are validated through the smooth coupon specimens. The proposed damage-based fatigue assessment approach describes, with reasonable accuracy, the total fatigue life of welded plate joints under high- and low-cycle fatigue actions. Subsequently, the study performs a tearing assessment on the ductile crack extension of the fatigue-induced crack. The tearing assessment diagram derives from the load-deformation curve of a single-edge notched bend, SE(B) specimen and successfully predicts the load-crack extension relation for the reported welded plate joints during the stable tearing process.

Successful nonsurgical treatment of type II dens invaginatus with 5 root canals using a self-adjusting file: a case report

  • George Taccio de Miranda Candeiro;Antonio Sergio Teixeira de Menezes;Ana Carolina Saldanha de Oliveira;Flavio Rodrigues Ferreira Alves
    • Restorative Dentistry and Endodontics
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    • v.48 no.2
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    • pp.17.1-17.8
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    • 2023
  • The present report describes the endodontic treatment of an Oehlers type II dens invaginatus in a maxillary lateral incisor with 5 root canals, an extremely rare condition. Apical periodontitis and related symptoms were noted. Cone-beam computed tomography was used to aid the diagnosis, reveal tooth morphology, and assist in canal location. The pulp chamber was carefully accessed, and the root canals were explored under magnification. All root canals were prepared with an R25 Reciproc Blue system and sodium hypochlorite (NaOCl) irrigation. After initial preparation, a self-adjusting file (SAF) with NaOCl and ethylenediaminetetraacetic acid was used to complement the disinfection. Additionally, calcium hydroxide medication was applied. Vertical compaction was used to fill the canals with a calcium silicate-based endodontic sealer and gutta-percha. After 12 months, the patient exhibited healing of the periapical region, absence of symptoms, and normal dental function. In conclusion, this nonsurgical treatment protocol was successful in promoting the cure of apical periodontitis. Both complementary disinfection with an SAF and use of calcium hydroxide medication should be considered when choosing the best treatment approach for dens invaginatus with very complex anatomy.

Quantification of the ichthyotoxic raphidophyte Chattonella marina complex by applying a droplet digital PCR

  • Juhee, Min;Kwang Young, Kim
    • ALGAE
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    • v.37 no.4
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    • pp.281-291
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    • 2022
  • Quantifying the abundance of Chattonella species is necessary to effectively manage the threats from ichthyotoxic raphidophytes, which can cause large-scale mortality of aquacultured fish in temperate waters. The identification and cell counting of Chattonella species have been conducted primarily on living cells without fixation by light microscopy because routine fixatives do not retain their morphological features. Species belonging to the Chattonella marina complex, including C. marina and C. marina var. ovata, had high genetic similarities and the lack of clear morphological delimitations between the species. To estimate the abundance of C. marina complex in marine plankton samples, we developed a protocol based on the droplet digital polymerase chain reaction (ddPCR) assay, with C. marina complex-specific primers targeting the internal transcribed spacer (ITS) region of the rDNA. Cell abundance of the C. marina complex can be determined using the ITS copy number per cell, ranging from 25 ± 1 for C. marina to 112 ± 7 for C. marina var. ovata. There were no significant differences in ITS copies estimated by the ddPCR assay between environmental DNA samples from various localities spiked with the same number of cells of culture strains. This approach can be employed to improve the monitoring efficiency of various marine protists and to support the implementation of management for harmful algal blooms, which are difficult to analyze using microscopy alone.

Case Report on the Five-year Survival and Complete Response of a Patient with Pancreatic Cancer Treated with Integrative Medicine (통합 의학 치료로 5년 생존 및 완전 관해에 도달한 췌장암 증례 보고 1례)

  • Yu-jin Jung;Jisoo Kim;Kyung-Dug Park;Yoona Oh;Beom-Jin Jeong;Sunhwi Bang
    • The Journal of Internal Korean Medicine
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    • v.44 no.3
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    • pp.562-577
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    • 2023
  • Objectives: This is a five-year survival and complete response (CR) report on pancreatic cancer treated with western medicine and Korean traditional medicine. Method: A 59-year-old woman diagnosed with pancreatic cancer visited ○○ Korean traditional medicine hospital after neoadjuvant chemotherapy and pylorus-preserving pancreaticoduodenectomy. She was treated with Korean traditional medicine, including acupuncture, abdominal moxibustion, wild ginseng pharmacopuncture, and herbal medicine, which was based on integrated medicine therapy (IMT), from March 2018 to September 2022. The tumor size was measured by scanning with computed tomography (CT), magnetic resonance imaging, and positron-emission tomography/CT. Adverse events were evaluated using laboratory conclusion and National Cancer Institute Common Terminology Criteria for Adverse Events version 5.0. Result: During four years and three months of treatment, IMT maintained safety. The patient finally reached five-year survival without any recurrence or complication (CR) on October 26, 2022. Conclusion: We suggest that an integrative approach including Korean traditional medicine can be a meaningful treatment option for pancreatic cancer. Further studies should be performed to establish the proper treatment protocol of integrative medicine for pancreatic cancer.

Using ranked auxiliary covariate as a more efficient sampling design for ANCOVA model: analysis of a psychological intervention to buttress resilience

  • Jabrah, Rajai;Samawi, Hani M.;Vogel, Robert;Rochani, Haresh D.;Linder, Daniel F.;Klibert, Jeff
    • Communications for Statistical Applications and Methods
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    • v.24 no.3
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    • pp.241-254
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    • 2017
  • Drawing a sample can be costly or time consuming in some studies. However, it may be possible to rank the sampling units according to some baseline auxiliary covariates, which are easily obtainable, and/or cost efficient. Ranked set sampling (RSS) is a method to achieve this goal. In this paper, we propose a modified approach of the RSS method to allocate units into an experimental study that compares L groups. Computer simulation estimates the empirical nominal values and the empirical power values for the test procedure of comparing L different groups using modified RSS based on the regression approach in analysis of covariance (ANCOVA) models. A comparison to simple random sampling (SRS) is made to demonstrate efficiency. The results indicate that the required sample sizes for a given precision are smaller under RSS than under SRS. The modified RSS protocol was applied to an experimental study. The experimental study was designed to obtain a better understanding of the pathways by which positive experiences (i.e., goal completion) contribute to higher levels of happiness, well-being, and life satisfaction. The use of the RSS method resulted in a cost reduction associated with smaller sample size without losing the precision of the analysis.

A Hybrid Transmission Scheme for Efficient Video Streaming (네트워크 및 버퍼 상태를 모두 고려한 혼합형태의 비디오 스트림 전송기법)

  • Lee, Sun-Hun;Chung, Kwang-Sue
    • Journal of KIISE:Information Networking
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    • v.34 no.4
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    • pp.276-286
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    • 2007
  • Existing streaming mechanisms have no consideration for the characteristics of streaming applications because they only consider network stability. In this paper, in order to overcome limitations of the previous work on video streaming, we propose a new video streaming mechanism called "HAViS(Hybrid Approach for Video Streaming)". The proposed mechanism includes more sophisticated features that consider both network and user requirements. Therefore, the HAViS mechanism improves the network stability by adjusting the sending rate of video stream based on the network state and it also provides the smooth playback by preventing the buffer underflow or overflow. Moreover, it is designed to take into consideration the streaming video content. Through the simulation, we prove that the HAViS mechanism efficiently uses the buffer resources and provides improved network stability and smooth playback.

Adaptive Mobile Sink Path Based Energy Efficient Routing Protocol for Wireless Sensor Network (무선 센서 네트워크에서 에너지 효율을 고려한 모바일 sink의 적응적 경로설정 방법)

  • Kim, Hyun-Duk;Yoon, Yeo-Woong;Choi, Won-Ik
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.36 no.12A
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    • pp.994-1005
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    • 2011
  • In this paper, we propose a novel approach to optimize the movement of mobile sink node, called AMSP(Adaptive Mobile Sink Path) for mobile sensor network environments. Currently available studies usually suffer from unnecessary data transmission resulting from random way point approach. To address the problem, we propose a method which uses the Hilbert curve to create a path. The proposed method guarantees shorten transmission distance between the sink node and each sensor node by assigning orders of the curve according to sensor node density. Furthermore, The schedule of the sink node is informed to all of the sensing nodes so that the Duty Cycle helps the network be more energy efficient. In our experiments, the proposed method outperforms the existing works such as TTDD and CBPER by up to 80% in energy consumption.

Prospective Multicenter Feasibility Study of Laparoscopic Sentinel Basin Dissection after Endoscopic Submucosal Dissection for Early Gastric Cancer: SENORITA 2 Trial Protocol

  • Eom, Bang Wool;Yoon, Hong Man;Min, Jae Seok;Cho, In;Park, Ji-Ho;Jung, Mi Ran;Hur, Hoon;Kim, Young-Woo;Park, Young Kyu;Nam, Byung-Ho;Ryu, Keun Won;Sentinel Node Oriented Tailored Approach (SENORITA) Study Group
    • Journal of Gastric Cancer
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    • v.19 no.2
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    • pp.157-164
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    • 2019
  • Purpose: Although standard radical gastrectomy is recommended after noncurative resection of endoscopic submucosal dissection (ESD) for early gastric cancer in most cases, residual tumor and lymph node metastasis have not been identified after surgery. The aim of this study is to evaluate the feasibility of sentinel node navigation surgery after noncurative ESD. Materials and Methods: This trial is an investigator-initiated, multicenter prospective phase II trial. Patients who underwent ESD for clinical stage T1N0M0 gastric cancer with noncurative resections were eligible. Qualified investigators who completed the prior phase III trial (SENORITA 1) are exclusively allowed to participate. In this study, 2 detection methods will be used: 1) intraoperative endoscopic submucosal injection of dual tracer, including radioisotope and indocyanine green (ICG) with sentinel basins detected using gamma-probe; 2) endoscopic injection of ICG, with sentinel basins detected using a fluorescence imaging system. Standard laparoscopic gastrectomy with lymphadenectomy will be performed. Sample size is calculated based on the inferior confidence interval of the detection rate of 95%, and the calculated accrual is 237 patients. The primary endpoint is detection rate, and the secondary endpoints are sensitivity and postoperative complications. Conclusions: This study is expected to clarify the feasibility of laparoscopic sentinel basin dissection after noncurative ESD. If the feasibility is demonstrated, a multicenter phase III trial will be initiated to compare laparoscopic sentinel node navigation surgery versus laparoscopic standard gastrectomy in early gastric cancer after endoscopic resection.

A Research on Low-power Buffer Management Algorithm based on Deep Q-Learning approach for IoT Networks (IoT 네트워크에서의 심층 강화학습 기반 저전력 버퍼 관리 기법에 관한 연구)

  • Song, Taewon
    • Journal of Internet of Things and Convergence
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    • v.8 no.4
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    • pp.1-7
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    • 2022
  • As the number of IoT devices increases, power management of the cluster head, which acts as a gateway between the cluster and sink nodes in the IoT network, becomes crucial. Particularly when the cluster head is a mobile wireless terminal, the power consumption of the IoT network must be minimized over its lifetime. In addition, the delay of information transmission in the IoT network is one of the primary metrics for rapid information collecting in the IoT network. In this paper, we propose a low-power buffer management algorithm that takes into account the information transmission delay in an IoT network. By forwarding or skipping received packets utilizing deep Q learning employed in deep reinforcement learning methods, the suggested method is able to reduce power consumption while decreasing transmission delay level. The proposed approach is demonstrated to reduce power consumption and to improve delay relative to the existing buffer management technique used as a comparison in slotted ALOHA protocol.

Pain management in periodontal therapy using local anesthetics and other drugs: an integrative review

  • Eduarda Cristina Santos;Daniela Huller;Sabrina Brigola;Marceli Dias Ferreira;Marcia Thais Pochapski;Fabio Andre dos Santos
    • Journal of Dental Anesthesia and Pain Medicine
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    • v.23 no.5
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    • pp.245-256
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    • 2023
  • Background: Surgical and non-surgical periodontal procedures often lead to postoperative pain. Clinicians use pharmacological methods such as anesthetics, anti-inflammatory drugs, and analgesics for relief. However, the multitude of options makes it challenging to select the best approach for routine dental care. Objective: This review aimed to describe previous studies regarding the pharmacological management used for pain control during periodontal procedures as well as factors that may interfere with patients' perception of pain. Methods: We included studies (period of 2000-2023, whose approach corresponded to the pharmacological protocols used for preoperative, trans-operative, and postoperative pain control in adult patients undergoing surgical and non-surgical periodontal therapy. Results: A total of 32 studies were included in the analysis, of which 17 (53%) were related to anesthetic methods and 15 (47%) were related to therapeutic protocols (anti-inflammatory/analgesic agents). These studies predominantly involved nonsurgical periodontal procedures. Studies have reported that factors related to age, type of procedure, and anxiety can influence pain perception; however, only seven of these studies evaluated anxiety. Conclusions: Numerous methods for pain control can be applied in periodontal therapy, which are accomplished through anesthetic methods and/or therapeutic protocols. Factors such as anxiety, age, and type of procedure are related to pain perception in patients. Thus, it is the responsibility of dentists to evaluate each clinical situation and define the best protocol to follow based on the literature.