• Journal of Preventive Medicine and Public Health
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• v.40 no.2
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• pp.145-149
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• 2007

Objectives : This study characterized the extent to which youth depressive symptoms, parental alcohol problems, and parental drinking account for differences in alcohol-related problems among a large sample of adolescent females. Methods : The stratified sample consists of 2077 adolescent females from twelve female-only high schools located in a large metropolitan city in the Republic of Korea. Students completed a questionnaire about alcohol use and alcohol problems, their parents' alcohol problems, and a number of risk and protective factors. Data were analyzed using tobit regression analyses to better characterize the associations among variables. Results : Almost two-thirds of students who consume alcohol had experienced at least one to two alcohol-related problems in their lives and 54.6% reported at least one current symptom of depression, with nearly one-third reporting two depressive symptoms. Two-thirds of the students indicated that at least one parent had an alcohol-related problem, and that approximately 29% had experienced several problems. Results of tobit regression analyses indicate that youth alcohol-related problems are positively associated with depressive symptoms (p<0.01) and parent drinking problems (p<0.05). Parental drinking is no longer significant when the variable parental attention is added to the model. Decomposition of the tobit parameters shows that for every unit of increase in depressive symptoms and in parent drinking problems, the probability of a youth experiencing alcohol problems increases by 6% and 1%, respectively. For every unit of increase in parental attention, the probability of youth experiencing drinking problems decreases by 5%. Conclusions : This study presents evidence that alcohol-related problems and depressive symptoms are highly prevalent among adolescent females. Although a comprehensive public health approach is needed to address drinking and mental health problems, different interventions are needed to target factors associated with initiation of alcohol problems and those associated with increased alcohol problems among those who already began experiencing such problems.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.38 no.2
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• pp.157-166
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• 2014

A light water reactor (LWR) fuel rod consists of zirconium alloy cladding tube and uranium dioxide pellets with a slight gap between them. The modeling of heat transfer across the gap between fuel pellets and the protective cladding is essential to understanding fuel behavior under irradiated conditions. Many researchers have been developing fuel performance codes based on finite element method (FE) to calculate temperature, stress and strain for multidimensional analysis. The gap conductance model for multi-dimension is difficult issue in terms of convergence and nonlinearity because gap conductance is function of gap thickness which depends on mechanical analysis at each iteration step. In this paper, virtual link gap element (VLG) has been proposed to resolve convergence issue and nonlinear characteristic of multidimensional gap conductance. In terms of calculation accuracy and convergence efficiency, the proposed VLG model has been evaluated for variable cases.

• Journal of the Korea Convergence Society
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• v.12 no.1
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• pp.231-242
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• 2021

The purpose of this study was to investigate the degree to which cyber counselors' psychological stress, Compassion fatigue and Compassion satisfaction affect exhaustion. 82 cyber counselors were surveyed, and 5 interviews were conducted. As a result of analysis to find out the degree of influence on exhaustion, it was found that Compassion satisfaction was a variable. In-depth interviews looked at the causes, consequences, and ways of overcoming exhaustion, and increased Compassion satisfaction, a positive emotion in the process of helping clients, lowers exhaustion, and shows that Compassion satisfaction is a protective factor to prevent exhaustion. Based on the research results, implications and limitations were discussed.

• Genomics & Informatics
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• v.20 no.3
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• pp.32.1-32.15
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• 2022

Malaria is a life-threatening disease, and Africa is still one of the most affected endemic regions despite years of policy to limit infection and transmission rates. Further, studies into the variable efficacy of the vaccine are needed to provide a better understanding of protective immunity. Thus, the current study is designed to delineate the effect of each dose of vaccine on the transcriptional profiles of subjects to determine its efficacy and understand the molecular mechanisms underlying the protection this vaccine provides. Here, we used gene expression profiles of pre and post-vaccination patients after various doses of RTS,S based on samples collected from the Gene Expression Omnibus datasets. Subsequently, differential gene expression analysis using edgeR revealed the significantly (false discovery rate < 0.005) 158 downregulated and 61 upregulated genes between control vs. controlled human malaria infection samples. Further, enrichment analysis of significant genes delineated the involvement of CCL8, CXCL10, CXCL11, XCR1, CSF3, IFNB1, IFNE, IL12B, IL22, IL6, IL27, etc., genes which found to be upregulated after earlier doses but downregulated after the 3rd dose in cytokine-chemokine pathways. Notably, we identified 13 cytokine genes whose expression significantly varied during three doses. Eventually, these findings give insight into the dual role of cytokine responses in malaria pathogenesis. The variations in their expression patterns after various doses of vaccination are linked to the protection as it decreases the severe inflammatory effects in malaria patients. This study will be helpful in designing a better vaccine against malaria and understanding the functions of cytokine response as well.

• Smart Structures and Systems
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• v.29 no.2
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• pp.301-309
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• 2022

Protective coatings are most widely used anticorrosive structures for steel structures. The corrosion under the coating damages the host material, but this damage is completely hidden. Therefore, a field-applicable under-coating-corrosion visualization method has been desired for a long time. Laser ultrasonic technology has been studied in various fields as an in situ nondestructive inspection method. In this study, a comparative analysis was carried out between a guided-wave ultrasonic propagation imager (UPI) and pulse-echo UPI, which have the potential to be used in the field of under-coating-corrosion management. Both guided-wave UPI and pulse-echo UPI were able to successfully visualize the corrosion. Regarding the field application, the guided-wave UPI performing Q-switch laser scanning and piezoelectric sensing by magnetic attachment exhibited advantages owing to the larger distance and incident angle in the laser measurement than those of the pulse-echo UPI. Regarding the corrosion visualization methods, the combination of adjacent wave subtraction and variable time window amplitude mapping (VTWAM) provided acceptable results for the guided-wave UPI, while VTWAM was sufficient for the pule-echo UPI. In addition, the capability of multiple sensing in a single channel of the guided-wave UPI could improve the field applicability as well as the relatively smaller size of the system. Thus, we propose a guided-wave UPI as a tool for under-coating-corrosion management.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.27 no.2
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• pp.104-112
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• 2024

Purpose: Immunosuppressive therapy is frequently administered to patients with inflammatory bowel disease (IBD), which may make them more susceptible to infections like hepatitis B. Methods: A cross-sectional study was conducted on patients aged 5-18 years diagnosed with IBD who visited a gastroenterology clinic along with controls who were the same age as the patients with IBD and were healthy overall. A logistic regression analysis using the independent variables of age, sex, race, disease phenotype, surgery, and medications and the dependent variable of adequate hepatitis B surface antibody (HBsAb) titers (>10 mIU/mL) was performed on quantitative serum HBsAb titers. Results: The study enrolled 62 patients, including 37 males and 25 females. Crohn's disease, ulcerative colitis, and indeterminate colitis were diagnosed in 16, 22, and 24 patients, respectively. Thirty-nine patients were taking corticosteroids at the time of the study, 42 were taking immunomodulators, and four were taking biologics. Compared to 44.7% of the control group, 9.3% of the patients had protective titers. Only 12 out of 62 patients had HBsAb titers greater than 10 million IU/mL. None of the patients who received biologics or corticosteroids and 3.2% of those who received immunomodulators were found to be seroimmuned. Conclusion: The younger patients had the highest titers. Patient-specific factors that may impact these low titers include the length of the patient's illness and the use of immunosuppressants.

• Journal of the Korean Society of Clothing and Textiles
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• v.28 no.12 s.138
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• pp.1554-1561
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• 2004

In the U.S., outdoor enthusiasts such as golfers have been focused on skin cancer prevention practices since their outdoor activities lead to extensive sun exposure during peak sun hours. The purposes of this study were to investigate golfers current sun protection behaviors and five attributes and their impacts on the intention to adopt UV specialized clothing based on Rogers' theory. UV specialized clothing as a preventive innovation is related to sun protection behaviors. However, there has been little effort to explain the intention to adopt a preventive innovation regarding health-related practices. With a convenience sampling method, a total of 158 useful questionnaires were collected. Ninety one percent were male golfers, and their age ranged from 16 to 80 years old(mean age=30 years). About $25\%$ reported to practice sun protection behaviors. About $70\%$ disagreed on the relative advantage, compatibility, observability, and triability of UV specialized shirts and reported the low intention to purchase it. Current sun protection behaviors and five attribute variables were entered in the multiple regression equation to explain the dependent variable of intention to adopt the innovation. Triability was the best predictor of the intention to adopt UV specialized shirts, followed by current sun protection behaviors, compatibility, and relative advantage. With four predictors, $45\%$ of the variance of intention to adopt was explained. The present study provides how the golfers current sun protection behaviors play important roles in explaining the intention to adopt the preventive innovation. Physical and functional features of UV specialized clothing were also significantly associated with their intentions to adopt it.

• Research in Plant Disease
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• v.17 no.3
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• pp.295-301
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• 2011

The effect of various fungicides on anthracnose of strawberry, caused by Colletotrichum gloeosporioides, was determined in vitro, and in greenhouse and field trials. The $EC_{50}$ values of benomyl were clearly different between two sensitive and resistant groups of isolates. Iminoctadine tris had lower $EC_{50}$ values than mancozeb and propineb as protective fungicides and the response of mancozeb, propineb and azoxystrobin was variable depending on the isolate. In the greenhouse, pre- and post- inoculation fungicide applications significantly reduced disease compared to the non-treated control. Propineb, mancozeb and azoxystrobin were effective in controlling the disease when applied prior to inoculation. Metconazole and prochloraz-Mn treatments as ergosterol biosynthesis-inhibiting fungicides had the lowest incidence of anthracnose. In the nursery field trials in 2009 and 2010, the reduced fungicide spray program provided similar levels of disease control compared to the calendar-based applications with captan. A reduced spray program based on efficacious fungicides such as prochloraz-Mn will be useful for strawberry growers and provide more options for controlling anthracnose in Korea.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.11
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• pp.259-272
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• 2019

Steel-concrete single-leaf blast-resistant doors are protective structures consisting of a steel box and reinforced concrete slab. By the domestic blast-resistant doors, the structure is not designed efficiently because few studies have examined the effects of variables, such as the blast pressure, rebar ratio, and steel plate thickness on the structural behavior. In this study, the structural behavior of the doors was analyzed using the FE method, and the support rotation and ductility ratio used to classify the structural performance were reviewed. The results showed that the deflection changes more significantly when the plate thickness increases than when the rebar spacing is a variable. This is because the strain energy absorbed by the door is reduced considerably when the plate thickness increases, and as a result, the maximum deflection becomes smaller. According to a comparison of the calculated values of the support rotation and the ductility ratio, the structural performance of the doors could be classified based on the support rotation of one degree and ductility ratio of three. On the other hand, more explosion tests and analytical studies will be needed to classify the damage level.

• Journal of Veterinary Clinics
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• v.21 no.3
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• pp.229-235
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• 2004

To characterize the recent outbreaks of canine distemper (CD) in Korea, we carried out epidemiological investigations by clinical observations, serum neutralizing (SN) antibody titer determination and RT-PCR on the 315 dogs which were clinically suspected as canine distemper virus (CDV) infection. One hundred and sixty two of 315 dogs were infected with CDV. Breed or gender did not seem to have effects on the prevalence of CD. The major part of dogs were in young age from 6 weeks to 18 weeks of age, and were not vaccinated or incompletely vaccinated. Clinical signs of dogs with CD were multi systemic and extremely variable. Dogs died from CD had significantly more ocular signs and neurologic signs than those of dogs survived (p<0.05). The SN titers against CDV of 157 (96.9%) dogs were under 1:16, which is less than protective level. One possible explanation for recent outbreaks of CD in Korea might be low antibody titers against CDV because of vaccination failure. Therefore, to reduce the impact of virulent infection in the dog population, dogs should be vaccinated adequately and prophylactic measures should include isolation of young dogs from the dog population until vaccination can be expected to provide protection.