• 한국화재소방학회논문지
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• 제29권1호
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• pp.7-11
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• 2015

유해화학물질 누출사고 시 피해 예상지역의 주민안전 확보를 위해 국내에서는 캐나다의 ERG를 기반으로 한 방호활동거리를 활용하고 있다. 그러나 국가별 지형적인 특성이나 기상조건 등이 상이하여 신뢰성 있는 대응에는 한계를 보여 왔다. 본 연구에서는 국내 특정 석유화학공단을 대상으로 지형자료, 기상조건 등을 반영한 AERMOD 모델링 분석을 통해 방호활동거리가 계절별, 지형별로 다소 차이가 있음을 알 수 있었다.

• 한국안전학회지
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• 제32권2호
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• pp.59-65
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• 2017

Calculation of the damage impact of chemical accidents is an important element in site, and the initial isolation distance and the protective action distances are significant factors in coping the chemical accident. In this study, three major cities that represent each Province were selected, and the safety distances were calculated considering regional climate conditions. The results were compared with the prescribed values in Emergency Response Guidebook. It is concluded that the regional meteorological conditions such as temperature, vapour pressure, relative humidity, wind speed, and cloud cover should be reflected in estimating the initial isolation distance and the protective action distance.

• Journal of Radiation Protection and Research
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• 제48권1호
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• pp.52-57
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• 2023

Background: Korea Atomic Energy Research Institute (KAERI) operates several nuclear research facilities licensed by Nuclear Safety and Security Commission (NSSC). The emergency preparedness requirements, GSR Part 7, by International Atomic Energy Agency (IAEA) request protection strategy based on the hazard assessment that is not applied in Korea. Materials and Methods: In developing the protection strategy, it is important to consider an accident scenario and its consequence. KAERI has tried the hazard assessment based on a hypothesis accident scenario for the major nuclear facilities. During the assessment, the safety analysis report of the related facilities was reviewed, the simulation using MELCOR, MACCS2 code was implemented based on a considered accident scenario of each facility, and the international guidance was considered. Results and Discussion: The results of the optimized protective actions were 300 m evacuation and 800 m sheltering for the High-Flux Advanced Neutron Application Reactor (HANARO), the evacuation to radius 50 m, the sheltering 400 m for post-irradiation examination facility (PIEF), 100 m evacuation or sheltering for HANARO fuel fabrication plant (HFFP) facility. Conclusion: The results of the optimized protective actions and its distances for the KAERI facilities for the maximum postulated accidents were considered in establishing the emergency plan and procedures and implementing an emergency exercise for the KAERI facilities.

• Geomechanics and Engineering
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• 제28권3호
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• pp.209-224
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• 2022

In this study, the numerical analysis model of π-beam explosion is established to compare and analyze the failure modes of the π-beam under the action of explosive loads, thus verifying the accuracy of the numerical model. Then, based on the numerical analysis of different protection forms of π beams under explosive loads, the peak pressure of π beam under different protection conditions, the law of structural energy consumption, the damage pattern of the π beam after protection, and the protection efficiency of different protective layers was studied. The testing results indicate that the pressure peak of π beam is relatively small under the combined protection of steel plate and aluminum foam, and the peak value of pressure decays quickly along the beam longitudinal. Besides, as the longitudinal distance increases, the pressure peak attenuates most heavily on the roof's explosion-facing surface. Meanwhile, the combined protective layer has a strong energy consumption capacity, the energy consumed accounts for 90% of the three parts of the π beam (concrete, steel, and protective layer). The damaged area of π beam is relatively small under the combined protection of steel plate and aluminum foam. We also calculate the protection efficiency of π beams under different protection conditions using the maximum spalling area of concrete. The results show that the protective efficiency of the combined protective layer is 45%, demonstrating a relatively good protective ability.

• Journal of Radiation Protection and Research
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• 제41권3호
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• pp.196-205
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• 2016

Background: The emergency planning zone (EPZ) of the city of Busan is divided into the precautionary actions zone (PAZ) and the urgent protective action planning zone; which have a 5-km radius and a 20-km to 21-km radius from the nuclear power plant site, respectively. In this study, we assumed that a severe accident occurred at Shin-Kori nuclear unit 3 and evaluated the dispersion speed of radiological material at each distance at various wind speeds, and estimated the effective dose equivalent and the evacuation time of PAZ residents with the goal of supporting off-site emergency action planning for the nuclear site. Materials and Methods: The total effective dose equivalent, which shows the effect of released radioactive materials on the residents, was evaluated using the RASCAL 4.2 program. In addition, a survey of 1,036 residents was performed using a standardized questionnaire, and the resident evacuation time according to road and distance was analyzed using the VISSIM 6.0 program. Results and Discussion: According to the results obtained using the VISSIM and RASCAL programs, it would take approximately 80 to 252.2 minutes for permanent residents to move out of the PAZ boundary, 40 to 197.2 minutes for students, 60 to 232.2 minutes for the infirm, such as elderly people and those in a nursing home or hospital, and 30 to 182.2 minutes for those temporarily within the area. Consequently, in the event of any delay in the evacuation, it is estimated that the residents would be exposed to up to $10mSv{\cdot}h^{-1}$ of radiation at the Exclusion Area Boundaries (EAB) boundary and $4-6mSv{\cdot}h^{-1}$ at the PAZ boundary. Conclusion: It was shown that the evacuation time for the residents is adequate in light of the time lapse from the initial moment of a severe accident to the radiation release. However, in order to minimize the evacuation time, it is necessary to maintain a system of close collaboration to avoid traffic congestion and spontaneous evacuation attempts.

• 약학회지
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• 제49권2호
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• pp.168-173
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• 2005

Alzheimers disease (AD) is the most prevalent form of neurodegenerations associated with aging in the human population. This disease is characterized by the extracellular deposition of beta-amyloid (A ${\beta}$) peptide in cerebral plaques. The A ${\beta}$ peptide is derived from the ${\beta}$-amyloid precursor protein ( ${\beta}$APP). Photolytic processing of ${\beta}$APP by ${\beta}$-secretase(beta-site APP-cleaving enzyme, BASE) and ${\gamma}$-secretase generates the A ${\beta}$ peptide. Several lines of evidence support that A ${\beta}$-induced neuronal cell death is major mechanisms of development of AD. Accordingly, the ${\beta}$-and ${\gamma}$-secretase have been implicated to be excellent targets for the treatment of AD. We previously found that sesaminol glucosides have improving effect on memory functions through anti-oxidative mechanism. In this study, to elucidate possible other mechanism (inhibition of ${\beta}$-and ${\gamma}$-secretase) of sesaminol glucosides, we examined the improving effect of sesaminol glucosides in the scopolamine (1 mg/kg/mouse)-induced memory dysfunction using water maze test in the mice. Sesaminol glucosides (3.75, 7.5 mg/kg/6ml/day p.o., for 3 weeks) reversed the latency time, distance and velocity by scopolamine in dose dependent manner. Next, ${\beta}$-and ${\gamma}$-secretase activities were determined in different regions of brain. Sesaminol glucosides dose-dependently attenuated scopolamine-induced ${\beta}$-secretase activities in cortex and hippocampous and ${\gamma}$-secretase in cortex. This study therefore suggests that sesaminol glucosides may be a useful agent for prevention of the development or progression of AD, and its inhibitory effect on secretase may play a role in the improving action of sesaminol glucosides on memory function.

• 한국산학기술학회논문지
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• 제21권8호
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• pp.60-66
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• 2020

본 연구에서는 화학사고 및 화학테러 대응 시 화학물질로부터 인명 및 환경을 보호하기 위한 경계구역 설정에 관하여 국·내외 사례 조사를 바탕으로 우리나라 실정에 적합한 경계구역 선정 개선방안을 제시하고자 하였다. 현재 다양한 관계부처에서는 공통적으로 hot zone, warm zone, cold zone으로 구분하여 사용 중이나 특정 지역에 대해서는 용어 활용 측면에서 상이한 의미로 혼용되고 있다. 따라서 경계구역을 기존 3개 지역에서 hot zone, warm zone, cold zone, safety zone 4개 지역으로 구분하여 활용할 것을 제시하였다. 그리고 warm zone을 관심지역, safety zone을 안전지역으로 용어를 정립하도록 한다. 기존에 적용하던 ERPG 급성노출기준은 다양한 노출시간을 고려하지 않기 때문에 장시간 노출상황 적용에 적합하지 않으므로 적용 우선순위를 AEGL, ERPG, PAC, IDLHs 순으로 하도록 한다. CARIS 정보제공 방안은 확산평가가 가능한 물질 또는 불가능한 물질이거나 실내누출 상황으로 구분하고 풍향신뢰선과 ERG의 초기이격거리 및 방호활동거리를 함께 표현하여 현장대응 및 주민대피 결정 정보자료로 활용될 수 있도록 한다.