• 제목/요약/키워드: Protection time

검색결과 2,887건 처리시간 0.029초

유기 게르마늄의 투여가 카드뮴 및 수은에 중독된 흰쥐 간장 및 신장조직의 metallothionein 형성에 미치는 영향 (Effects of Organic Germanium on Metallothionein Induction in Liver and Kidney of Cadmium and Mercury Intoxicated Rats)

  • 이효민;정용
    • 약학회지
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    • 제35권2호
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    • pp.99-110
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    • 1991
  • This study was initiated to investigate the effects of organic germanium on cadmium and mercury intoxication. The effect was determined by the metallothionein induction in liver and kidney. Male rats (Sprague-Dawley) were treated with CdCI$_{2}$ (2mg/kg), HgCI$_{2}$ (1 mg/kg) and organic germanium (GE-132) (100 mg/kg) in single and in combination via intraperitoneal injection or intragastric administration every other days for 17 days. Experimental animals were sacrificed after 7, 12 and 17 days treatment. The serum transaminase activities (SGOT, SGPT), concentration of metal and metallothionein, metal-binding capacity of metallothionein in liver and kidney were determined and pathomorphological observations were undertaken. The combined treatment of GE-132 and CdCI$_{2}$ significantly decreased the increment of serum transaminase activities in rats treated with CdCI$_{2}$ only, but the combined treatment of GE-132 and HgCI$_{2}$ did not affect to activities of transaminases induced by mercury only. The concentration of metals (Cd and Hg) except Ge in the liver and kidney of rats increased with the time of treatment. Mercury concentration in kidney of rat treated with HgCI$_{2}$ only was significantly higher than the combined treatment of GE-132 and HgCI$_{2}$. The combined treatment of GE-132 and CdCI$_{2}$ significantly increased the concentration of metallothionein in liver compared to the CdCI$_{2}$ only, although the concentration of cadmium in liver were not significantly different between two groups. This indicates that GE-132 decreased toxicity of cadmium in liver by promoting metallothionein induction. There were no significant differences in metallothionein concentration in liver and kidney of rats between the combined treatment of GE-132 and HgCI$_{2}$ and HgCI$_{2}$ only. Metal-binding capacity of metallothionein varied with each time intervals in liver and kidney of metals treated rats except the liver of the combined treatment of GE-132 and CdCI$_{2}$. This finding explains the concentration of metallothionein in liver keeps abreast with the concention of metal. Furthermore, the combined treatment of GE-132and CdCl$_{2}$ revealed pathologically less changes in liver tissue than CdCl$_{2}$ only; the damages of liver cell, such as lobular necrosis and portal inflammation, were relieved and appeared more later. From the above results, organic germanium is considered to have some beneficial effect on the protection of liver from the cadmium intoxication.

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개심술 환자의 퇴원후 간호요구에 대한 조사연구 (Post Discharge Nursing Needs of Patients with Open Heart Surgery)

  • 김명희
    • 대한간호학회지
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    • 제23권4호
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    • pp.664-677
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    • 1993
  • The purpose of this study was to provide basic data for the development of educational material in Korean for patient3 being discharge after open heart surgery. The subjects were 45 adult patients who were seen in the out -patient department of the thoracic surgery unit of P University hospital between February 1993 and May 1993. The data were collected through a chart review and interview. Nursing needs, and the patients status related to diet, activity, medication, physical and psychoemotional limitations were analyzed. The results are summarized as follows ; 1. Mitral valve replacement was the most frequent type of surgery(91.2%). In most cases, a mechanical valve was used (91.0%) . The duration of admission after the operation was two to four weeks for most of the patients(48.9%). The follow-up period was between one and two years for 28.9% of the patients and below 6 years for all of the patients. 2. Many Patients didn’t know the importance of a low salt diet(57.8%), and did not get any education on low salt diet (66.7%). Gimchi was included as one of the most commonly ingested foods (77.8%). All of the patients indicated nursing needs related to education about low salt diets and further they indicated a major interest in foods that are harmful (57.7%) or foods that are safe(51.1% ). 3. Most patients did not recognize the need for limitations on physical activity(84.4%). Further, 31.1% of them could not return to work at the time of the study. All patients had nursing needs related to physical activity, with the most frequent questions being about the permissble degree of activity and special cautions dictated by their illness (60.0%). 4. Many patients were ignorant of the necessity of medication(55.6%) . Forty percent of the patients were taking additional drugs, usually herb drugs. The time and duration of medication and the side effects of drugs were common concerns (57.7%) related to nursing. needs about medication and were mentioned by all of the patients. 5. All of the patients complained of physical discomfort including the following : memory disturbance(62.2%), weight gain(60.0%), chest tightness (55.6%), hair loss(51.1%), sleep disturbance(46.7%) and other symptoms in that order of frequency. Nursing needs related to physical condition were a concern for all of them. The viability and function of the replaced valve(53.3%) and weight gain(60.0%) were mal or concerns. 6. Looking at their psychoemotional condition it was found that 36 patients(80.0%) were emotionally unstable. The causes were physical discomfort(17 patients), insufficient knowlege of open heart surgery(6 patients), fear of death(6 patients), familial over protection(2 patients ) and lack of support (5 patients).

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광개시제, 올리고머 그리고 Talc 함량에 따른 아크릴계 코팅제의 UV경화 및 박리특성 (UV Curing and Peeling Characteristics of Acrylic Coating Ink with Various Amounts of Photoinitiator, Oligomer and Talc)

  • 양지우;서아영;이철우
    • 공업화학
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    • 제24권5호
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    • pp.499-506
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    • 2013
  • 전자 통신 산업의 발달로 터치 패널용 강화유리의 사용량이 급격히 증가함에 따라, 판유리 가공 공정 중 유리표면을 보호하기 위한 용도로 사용되는 UV경화형 코팅용액의 사용량이 함께 증가하고 있다. UV경화형 코팅은 열경화형에 비해 경화시간이 매우 짧고, 용제를 사용하지 않는 장점이 있다. 알칼리에 의한 박리 특성을 부여하기 위해 산성 고분자 styrene-acrylic acid copolymer를, 모노머로는 아크릴기가 각각 1개, 2개, 6개인 2-hydroxyl methylacrylate, 1,6-hexanediol diacrylate 그리고 dipentaerythritol hexaacrylate를 사용하였다. 광개시제로는 HP-8, TPO 및 DETX 3종을 조합하여 사용하였고 올리고머로는 bisphenol A epoxy diacrylate를 사용하였다. 본 연구에서는 산성 고분자와 아크릴계 모노머의 함량을 일정하게 유지하면서 광개시제, 올리고머, 그리고 첨가제인 talc의 함량을 변화시키며 실험을 수행하여 광개시제에 따른 제반 물성의 연계성을 고찰하였다. 시험결과 두 가지 이상의 광개시제를 사용해야 경도를 4H 이상 얻을 수 있었고 특히 TPO를 첨가하면 코팅막의 박리 형태를 시트형태로부터 조각형태로 조절하는 것이 가능하였다. 올리고머 함량이 증가하면 경도와 접착성이 증가하지만 박리시간 역시 증가하였고 talc 함량은 20 wt%에서 가장 우수한 결과를 나타내었다.

실시간 멀티미디어 통신을 위한 의미 기반 채널 파워 할당 기법 (Optimal Channel Power Allocation by Exploiting Packet Semantics for Real-time Wireless Multimedia Communication)

  • 홍성우;원유집
    • 전자공학회논문지CI
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    • 제47권1호
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    • pp.171-184
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    • 2010
  • 본 연구에서는 실시간 멀티미디어 서비스의 QoS를 향상시키기 위해 계층 통합 최적화 기법을 통한 새로운 파워 할당 기법을 소개한다. 각각의 패킷이 QoS에 미치는 영향이 다르므로, 항상 패킷 손실의 감소가 QoS의 향상으로 이어지지는 않는다. 본 연구에서는 패킷이 QoS에 미치는 영향을 정량화 하여 이를 바탕으로 파워를 할당하는 기법을 개발하였다. 다이내믹 프로그래밍 기법을 사용하여 파워소모를 최소화하면서 QoS를 극대화하는 적절한 파워 값을 발견하였으며, 실험을 위해 널리 공개된 비디오 클립을 사용하였다. 네트워크 시뮬레이터 (network simulator version 2)를 통하여 시뮬레이션을 수행하였으며, 성능 평가를 위해 클라이언트 단에 디코딩엔진을 삽입하여 원본 영상과 전송된 영상을 비교, PSNR을 도출하였다. 패킷 세만틱 정보를 기반으로 적절한 파워를 할당한 결과 기존의 기법에 비해 QoS가 크게 향상되는 것을 확인할 수 있었으며, 이는 본 논문에서 제안된 기법이 보다 중요한 패킷에 대한 차별적인 보호 기법이 적용된 결과임을 각 프레임 손실에 대한 조사로 알 수 있었다. 해당 기법의 적용을 통해 I 프레임의 경우 손실이 최대 29%에서 2%이내로 감소하는 것을 확인할 수 있었으며, 같은 결과를 나타낼 때, 파워 소모를 최대 약 20%까지 감소시키는 것을 확인할 수 있었다.

전쟁의 기억: 전재에서 자연재해로 - 6.25전쟁기 회화 작품에 나타난 피난 이미지 (The Memory of War : from War Damages to Natural Disaster -The Evacuation Image Portrayed in Korean War Painting)

  • 조은정
    • 미술이론과 현장
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    • 제13호
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    • pp.7-33
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    • 2012
  • The memory of the Korean War is about the time period when people lived toughly during evacuation, due to being exposed to the natural climate such as intense cold or heat without any protection, leaving their comfortable home and living in temporary built shelters which were barely enough to avoid the wind. 'Death is concealed and only the figures of evacuation for survival were expressed, just as how the government ordered. Since the experience of the battlefield is personal and fragmentary, that is broken into pieces, it does not have compatibility. As war is a distorted experience that cannot be placed in a big picture, it is not possible to take a view of the war's big picture. Having this individualized experience as a common collective memory is an issue and it is the will that people tries to pursue. The reason why the evacuees from north to south, and as well as from the south to further south were all able to be adopted as the theme of artworks due to the military action that emptied the occupied territories of the North Korean Army under the forced removal command. In such situations, the natural state of the 'snow' was like a symbol of the 1.4 Recession. The group of people who were thrown into the intense cold displaced the war damage of loosing their base livelihood, and symbolized the obedient citizens who faithfully follow their government's command. The figure of advocating anti-communism is projected as a figure of a refugee during cold winter-time and it contains ones past which he or she obeyed its own country's commands. Evacuation, especially the evacuation during the winter is a visual device that can confirm these kinds of country's command. The consequences were same for the artists as well. Therefore, the situation being communal could be found due to the individual experiences during war are ideological. The image of the refuge shown in the picture played the role of strengthening the consciousness of defecting to South Korea into the meaning of the 'Finding Freedom.' I would like to express that the reason of them leave their home during the harsh winter is in order to avoid the oppression of the Communist Party. The evacuation that people went through was not to 'Finding Freedom', but 'To Survive'. Later, this evacuation has been imprinted as a behavior of choosing free Republic of Korea, which was an ideological issue. Anti-communism was the rule of survival in South Korea society, and people have the tendency to remember what they want to remember. As it is not the people who possesses an incident, but the memory that possesses ones, people cover their memory with disguised plots in order to forget the violence and to live a different prologue. They share the incident of violence as a hurtful memory. The tragedy of the Korean War was the result of Ideology and being in between the powerful nations' rights, but the violence during the war has been depicted as a natural disaster, which was the evacuation in heavy snow.

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전통춤프로그램이 가정위탁아동의 대인관계향상에 미치는 영향에 관한 연구 (A Study on the Effects of Traditional Dance Program on the Improvement of Interpersonal Relationships of Foster Care Children)

  • 배나래;조태선
    • 한국산학기술학회논문지
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    • 제18권12호
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    • pp.242-247
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    • 2017
  • 가정위탁제도는 일반적으로 친부모로부터 적절한 보호와 보살핌을 받을 수 없는 아동이 위탁가정에서 친부모를 대신하여 규정된 시간 안에 계획 하에 구성된 필요한 보호를 받으면서 가정의 기능을 보완하는 사회복지서비스이다. 위탁보호아동들이 겪게 되는 정서적 어려움 중 큰 부분은 대인관계 부적응이다. 긍정적이지 못한 대인관계로 인해 낮은 자아존중감이 나타나며, 사회적 관계형성에 어려움을 겪게 된다. 따라서 본 연구는 대전광역시에 거주하는 위탁아동들을 대상으로 전통춤 프로그램을 통해 가정위탁아동의 대인관계를 향상 시키며 이를 통한 대인관계 효과를 검증하여 전통춤프로그램이 대인관계프로그램으로 활용될 수 있는 기초자료를 마련하는데 목적이 있다. 전통춤프로그램을 통해 참여 아동들의 대인관계에 대한 사전 점수와 사후 점수를 비교해 본 결과, 프로그램 후 대인관계 점수가 상승하였다. 아동간의 친밀감 형성 및 의사소통 등이 향상됨을 볼 수 있었다. 참가자들은 초기에는 프로그램에 적극성이 떨어졌으나 프로그램 중반으로 갈수록 흥미를 느끼고 적극적인 모습이 자주 관찰 되었다. 대부분의 참여자들이 프로그램 중반부로 갈수록 친밀감이 형성되면서 의사소통 횟수가 증가 하였으며, 또래 관계에 있어서 자신감이 향상 되는 모습을 보였다. 본 연구는 전통춤을 활용한 대인관계 향상에 대한 기초연구로 추후연구에서는 다양한 내용으로 구성된 전통춤프로그램을 장기간에 걸쳐 적용함으로서 가정위탁아동의 정서적, 사회적, 문화적 등 다양한 영역에서의 대인관계능력이 향상 될 수 있는 기회가 되도록 해야 할 것이다.

동적 프레디킷 : 허포크라테스 XML 데이타베이스를 위한 효율적인 액세스 통제 방법 (Dynamic Predicate: An Efficient Access Control Mechanism for Hippocratic XML Databases)

  • 이재길;한욱신;황규영
    • 한국정보과학회논문지:데이타베이스
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    • 제32권5호
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    • pp.473-486
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    • 2005
  • 최근에 Agrawal 등이 제안한 히포크라테스 데이타베이스는 관계형 데이타베이스에 프라이버시 보호 기능을 추가한 데이타베이스 모델이다. 본 논문의 저자들은 히포크라테스 데이타베이스 모델을 XML 데이타베이스에 적용할 수 있도록 확장한 히포크라테스 XML 데이타베이스 모델[4]을 제안하였다. 본 논문에서는 동적 프레디킷(dynamic predicate)이라는 새로운 개념을 제안하고, 히포크라테스 XML 데이타베이스 모델에서의 액세스 통제에 이 개념을 적용한다. 동적 프레디킷은 권한에 의해 액세스가 허용되는지를 결정하는데 적용될 수 있는 질의 처리 도중에 동적으로 생성되는 조건을 나타낸다. 동적 프레디킷은 권한 검사를 질의 계획에 효과적으로 통합하여 액세스가 허용되지 않은 엘리먼트들이 질의 처리 과정에서 일찍 제외될 수 있게 해준다. 합성 데이타와 실제 데이타를 사용하여 기존의 액세스 통제 방법과 질의 처리 시간을 비교하는 다양한 실험을 수행한 결과, 본 논문에서 제안한 액세스 통제 방법은 하향식 액세스 통제 방법에 비하여 최대 219배, 상향식 액세스 통제 방법에 비하여 최대 499배 성능을 향상시킴을 보였다. 본 논문의 주요 공헌은 히포크라테스 XML 데이타베이스 모델 상에서 동적 프레디킷을 사용하여 액세스 통제 방법을 질의 계획에 효과적으로 통합할 수 있도록 한 것이다.

물류 및 유통산업의 블록체인 활용과 정책 방향 (Application and Policy Direction of Blockchain in Logistics and Distribution Industry)

  • 김기흥;심재현
    • 산경연구논집
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    • 제9권6호
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    • pp.77-85
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    • 2018
  • Purpose - The purpose of this study is to subdivide trade transaction-centered structure in a logistics/distribution industry system to apply blockchain, to establish and resolve with which types of technology, and to provide policy direction of government institution and technology to apply blockchain in this kind of industry. Research design, data, and methodology - This study was conducted with previous researches centered on cases applied in various industry sectors on the basis of blockchain technology. Results - General fields of blockchain application include digital contents distribution, IoT platform, e-Commerce, real-estate transaction, decentralized app. development(storage), certification service, smart contract, P2P network infrastructure, publication/storage of public documents, smart voting, money exchange, payment/settlement, banking security platform, actual asset storage, stock transaction and crowd funding. Blockchain is being applied in various fields home and abroad and its application cases can be explained in the banking industry, public sector, e-Commerce, medical industry, distribution and supply chain management, copyright protection. As examined in the blockchain application cases, it is expected to establish blockchain that can secure safety through distributed ledger in trade transaction because blockchain is established and applied in various sectors of industries home and abroad. Parties concerned of trade transaction can secure visibility even in interrupted specific section when they provide it as a base for distributed ledger application in trade and establish trade transaction model by applying blockchain. In case of interrupted specific section by using distributed ledger, blockchain model of trade transaction needs to be formed to make it possible for parties concerned involved in trade transaction to secure visibility and real-time tracking. Additionally, management should be possible from the time of contract until payment, freight transfer to buyers through land, air and maritime transportation. Conclusions - In order to boost blockchain-based logistics/distribution industry, the government, institutionally, needs to back up adding legal plan of shipping, logistics and distribution, reviewing standardization of electronic switching system and coming up with blockchain-based industrial road maps. In addition, the government, technologically, has to support R&D for integration with other high technology, standardization of distribution industry's blockchain technology and manpower training to expand technology development.

Clinical Results of Ascending Aorta and Aortic Arch Replacement under Moderate Hypothermia with Right Brachial and Femoral Artery Perfusion

  • Kim, Jong-Woo;Choi, Jun-Young;Rhie, Sang-Ho;Lee, Chung-Eun;Sim, Hee-Je;Park, Hyun-Oh
    • Journal of Chest Surgery
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    • 제44권3호
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    • pp.215-219
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    • 2011
  • Background: Selective antegrade perfusion via axillary artery cannulation along with circulatory arrest under deep hypothermia has became a recent trend for performing surgery on the ascending aorta and aortic arch and when direct aortic cannulation is not feasible. The authors of this study tried using moderate hypothermia with right brachial and femoral artery perfusion to complement the pitfalls of single axillary artery cannulation and deep hypothermia. Materials and Methods: A retrospective analysis was performed on 36 patients who received ascending aorta or aortic arch replacement between July 2005 and May 2010. The adverse outcomes included operative mortality, permanent neurologic dysfunction and temporary neurologic dysfunction. Results: Of these 36 patients, 32 (88%) were treated as emergencies. The mean age of the patients was 61.9 years (ranging from 29 to 79 years) and there were 19 males and 17 females. The principal diagnoses for the operation were acute type A aortic dissection (31, 86%) and aneurysmal disease without aortic dissection (5, 14%). The performed operations were ascending aorta replacement (9, 25%), ascending aorta and hemiarch replacement (13, 36%), ascending aorta and total arch replacement (13, 36%) and total arch replacement only (1, 3%). The mean cardiopulmonary bypass time was $209.4{\pm}85.1$ minutes, and the circulatory arrest with selective antegrade perfusion time was $36.1{\pm}24.2$ minutes. The lowest core temperature was $24{\pm}2.1^{\circ}C$. There were five deaths within 30 post-op days (mortality: 13.8%). Two patients (5.5%) had minor neurologic dysfunction and six patients, including three patients who had preoperative cerebral infarction or unconsciousness, had major neurologic dysfunction (16.6%). Conclusion: When direct aortic cannulation is not feasible for ascending aorta and aortic arch replacement, the right brachial and femoral artery can be used as arterial perfusion routes with the patient under moderate hypothermia. This technique resulted in acceptable outcomes.

팔로사징증의 근치 수술에 관한 임상적 고찰 (Clinical Review about Corrective Surgery of Tetralogy of Fallot)

  • 조광현
    • Journal of Chest Surgery
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    • 제24권7호
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    • pp.674-684
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    • 1991
  • The surgical treatment of tetralogy of Fallot [TOF] was initiated by Blalock and Taussig in 1945 with the establishment of the subclavian artery to pulmonary artery anastomosis. In an imaginative and daring effort, in 1954, Lillehei and collaborators [1955] using controlled cross-circulation, carried out the first intracardiac repair of TOF by closing the ventricular septal defect [VSD] and relieving the pulmonary stenosis under direct vision. Nowadays, total correction is the ideal operation for treatment of TOF and is accomplished with extracorporeal circulation. And the results of surgery for TOF have steadily improved over the years, thanks to important contributions of many surgeons. Nevertheless because of its protean physiologic and anatomic presentation, TOF continues to offer challenges to cardiologist and cardiac surgeons. Thirty two cases of TOF have undergone total corrective surgery using extracorporeal circulation in the Department of Thoracic & Cardiovascular Surgery, Pusan Paik Hospital, Inje University, from Oct. 1985 to Feb. 1990. Clinical considerations were applied to these cases and the results were obtained as follows. 1. The heart lung machine used for extracorporeal circulation was SarnsO 7000, 5-head roller pump, and the number and type of oxygenators were 10 of bubble type and 22 of membrane type. The mean bypass time was 148.9 minutes and the mean aortic cross clamp time was 123.8 minutes. The GIK [glucose-insulin-potassium] solution was used as cardioplegic solution for myocardial protection during operation. 2. 20 cases were male and 12 were female, the mean age was 8 years old and the mean body weight was 25Kg. 3. The preoperative symptoms were cyanosis [29 cases], squatting [27 cases] and etc. The mean values of preoperative Hb., Hct., and SaO2 were 16.5 gm /dl, 50.3%, and 78.5%. 4. Combined anomalies were noticed in 16 cases [50%]. Among them 10 cases were PFO and 6 cases were ASD. 5. The degree of aorta overriding were 25% in 5 cases, 25 ~ 50% in 22 cases and above 50% in 5 cases. The dPA/Ao [ratio of diameter of pulmonary artery trunk to ascending aorta] were below 25% in 5 cases, 25 ~ 50% in 10 cases, 50 ~ 70% in 6 cases and above 75% in 11 cases. 6. The types of RVOT [right ventricular outflow tract] stenosis were valvular and infundibular in 14 cases [43.6%], diffuse hypoplastic type in 12 cases [37.5%], infundibular in 5 cases, and valvular and supravalvular in 1 case. 7. One stage radical corrective surgery was applied to the all cases. In widening of the RVOT, 3 types of patches were used: MVOP [monocusp ventricular outflow patch, Polystan BioprosthesesO] in 3 cases, knitted Dacron vessel patches in 2 cases, and double layer with bovine pericardium and woven Dacron prosthesis in 26 cases. 8. Postoperative complications were occurred in 15 cases. Among them, low output syndrome were occurred in 10 cases [31.3%] and 2 of them were expired postoperatively.

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