• 제목/요약/키워드: Prospective approach

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Association between dietary intake, body measurements, and urinary bone resorption markers in young adults with osteopenia and osteoporosis: a cross-sectional study

  • Mi-Hyun Kim;Mi-Kyeong Choi
    • 대한지역사회영양학회지
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    • 제28권4호
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    • pp.282-292
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    • 2023
  • Objectives: Bone health in early adulthood, as individuals approach peak bone mass, plays a critical role in preventing osteoporosis later in life. This study aimed to investigate the associations between lifestyle and dietary factors, anthropometric measurements, and urinary bone resorption markers in young adults. Methods: A cross-sectional study was conducted with 100 healthy Korean adults (50 men and 50 women) in their 20s and early 30s. Bone mineral density (BMD), anthropometric measurements, dietary intake (24-hour recall), and urinary bone resorption indicators (deoxypyridinoline and N-terminal telopeptide of type I collagen) were analyzed. Variables were compared between the osteopenia and osteoporosis groups (OSTEO group: 30% men and 60% women) and the healthy control group. Results: Men in the OSTEO group were significantly taller than those in the control group (P < 0.05). Women in the OSTEO group had significantly lower body weight and body composition (muscle and body fat) than those in the normal group (P < 0.01). Men in the OSTEO group had a significantly higher intake of animal calcium (Ca) than those in the normal group (P < 0.05). Women in the OSTEO group had significantly higher dietary fiber, vitamin A, Ca, plant Ca, and potassium intake than did those in the normal group (P < 0.05). There were no significant differences in caffeinated beverage consumption, eating habits, or urinary bone resorption indicators between the OSTEO and control groups of either sex. Conclusions: In our study of young South Korean adults, we observed low bone density levels, with particularly low BMD in taller men and underweight women. We found a higher nutrient intake in the OSTEO group, indicating the possibility of reverse causality, a phenomenon often found in cross-sectional studies. Therefore, there is a need to further elucidate dietary factors related to osteoporosis in young adults through prospective cohort studies involving a larger population.

근위축성 측삭경화증 환자의 한방치료에 대한 국내 연구 문헌 고찰 (A Review of Korean Studies on Amyotrophic Lateral Sclerosis Treated with Traditional Korean Medicine)

  • 이혜윤;박혜림;이득주;이인;홍진우;권정남
    • 대한중풍순환신경학회지
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    • 제16권1호
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    • pp.89-102
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    • 2015
  • ■ Objectives This study aimed to investigate the domestic research trend about Amyotrophic Lateral Sclerosis(ALS) treated with Traditional Korean Medicine(TKM). ■ Methods Searches of two major TKM databases were conducted for articles published up to July 2015. Searching keyword was "Lou Gehrig's disease" OR "amyotrophic lateral sclerosis". Studies dealt TKM for ALS were included. ■ Results 18 studies were met our inclusion criteria(two prospective studies, one retrospective study, one follow-up study, 14 case reports). Complex TKM intervention of herbal medication, acupuncture and pharmacopuncture was the most frequently used treatment. Individually, herbal medication was the most frequent followed by acupuncture. Short-term assessment showed improvement in ALS symptoms but long-term assessment showed progression of disease. Accessory symptoms including depression, anxiety and insomnia were improved in four studies. ■ Conclusion For more definite evidence, larger studies with long-term follow-up period are needed. Moreover, benefits that TKM can provide for ALS patients as a part of multi-disciplinary approach should be studied in depth.

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Risk factors for orthodontic fixed retention failure: A retrospective controlled study

  • Kaat Verschueren;Amit Arvind Rajbhoj;Giacomo Begnoni;Guy Willems;Anna Verdonck;Maria Cadenas de Llano-Perula
    • 대한치과교정학회지
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    • 제53권6호
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    • pp.365-373
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    • 2023
  • Objective: To investigate the potential correlation between fixed orthodontic retention failure and several patient- and treatment-related factors. Methods: Patients finishing treatment with fixed appliances between 2016 and 2017 were retrospectively included in this study. Those not showing fixed retention failure were considered as control group. Patients with fixed retention failure were considered as the experimental group. Additionally, patients with failure of fixed retainers in the period of June 2019 to March 2021 were prospectively identified and included in the experimental group. The location of the first retention failure, sex, pretreatment dental occlusion, facial characteristics, posttreatment dental occlusion, treatment approach and presence of oral habits were compared between groups before and after treatment separately by using a Fisher exact test and a Mann-Whitney U test. Results: 206 patients with fixed retention failure were included, 169 in the mandibular and 74 in the maxillary jaws. Significant correlations were observed between retention failure in the mandibular jaws and mandibular arch length discrepancy (P = 0.010), post-treatment growth pattern (P = 0.041), nail biting (P < 0.001) and abnormal tongue function (P = 0.002). Retention failure in the maxillary jaws was more frequent in patients with IPR in the mandibular jaws (P = 0.005) and abnormal tongue function (P = 0.021). Conclusions: This study suggests a correlation between fixed retention failure and parafunctional habits, such as nail biting and abnormal tongue function. Prospective studies with larger study populations could further confirm these results.

집중치료 경험이 중환자실 생존자의 집중치료 후 증후군에 미치는 영향: PLS-구조모형 적용 (Effects of Intensive Care Experience on Post-Intensive Care Syndrome among Critical Care Survivors : Partial Least Square-Structural Equation Modeling Approach)

  • 조영신;강지연
    • 중환자간호학회지
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    • 제17권1호
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    • pp.30-43
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    • 2024
  • Purpose : Post-intensive care syndrome (PICS) is characterized by a constellation of mental health, physical, and cognitive impairments, and is recognized as a long-term sequela among survivors of intensive care units (ICUs). The objective of this study was to explore the impact of intensive care experience (ICE) on the development of PICS in individuals surviving critical care. Methods : This secondary analysis utilized data derived from a prospective, multicenter cohort study of ICU survivors. The cohort comprised 143 survivors who were enrolled between July and August 2019. The original study's participants completed the Korean version of the ICE questionnaire (K-ICEQ) within one week following discharge from the ICU. Of these, 82 individuals completed the PICS questionnaire (PICSQ) three months subsequent to discharge from hospital. The influence of ICE on the manifestation of PICS was examined through Partial Least Squares-Structural Equation Modeling (PLS-SEM). Result : The R2 values of the final model ranged from 0.35 to 0.51, while the Q2 values were all greater than 0, indicating adequacy for prediction of PICS. Notable pathways in the relationship between the four ICE dimensions and the three PICS domains included significant associations from 'ICE-awareness of surroundings' to 'PICS-cognitive', from 'ICE-recall of experience' to 'PICS-cognitive', and from 'ICE-frightening experiences' to 'PICS-mental health'. Analysis found no significant moderating effects of age or disease severity on these relationships. Additionally, gender differences were identified in the significant pathways within the model. Conclusion : Adverse ICU experiences may detrimentally impact the cognitive and mental health domains of PICS following discharge. In order to improve long-term outcomes of individuals who survive critical care, it is imperative to develop nursing interventions aimed at enhancing the ICU experience for patients.

CFD를 이용한 도심내 드론 비행 경로 계획 및 안전성 평가 (CFD-based Path Planning and Flight Safety Assessment for Drone Operation in Urban Areas)

  • 김건홍;황아영;김효영;김연명
    • 항공우주시스템공학회지
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    • 제18권2호
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    • pp.40-46
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    • 2024
  • 본 연구는 도심 지역에서 드론 비행 경로의 계획과 안전성 평가를 개선하기 위해 CFD(Computational Fluid Dynamics)를 활용하는 방법을 제시한다. 도심 지역에서의 드론 비행은 빠르게 증가하고 있는데, 아직 경로 계획 및 안전성 평가 방법이 정립되어 있지 않으며 실험적으로 접근하고 있어 위험성이 높은 문제가 있다. 이에 본 연구에서는 CFD를 활용하여 드론과 건물 간 복잡한 3D 공간에서의 유체 역학을 고려한 비행 경로를 계획하고, 각 경로의 안전성을 정량적으로 평가하였다. 이를 위해 김천 혁신도시를 대상 지역으로 설정하여 지형과 건물 데이터 수집 및 비행 예상 경로를 선정하였다. CFD 유동 해석을 통해 비행 시뮬레이션과 안전성 평가를 위한 기본 데이터를 마련하였으며 이를 통해 드론이 제안된 비행 경로로 비행하였을 때 환경 유동에 의한 안전성 평가를 수행하였다.

Trends in Hybrid Cultured Meat Manufacturing Technology to Improve Sensory Characteristics

  • AMM Nurul Alam;Chan-Jin Kim;So-Hee Kim;Swati Kumari;Seung-Yun Lee;Young-Hwa Hwang;Seon-Tea Joo
    • 한국축산식품학회지
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    • 제44권1호
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    • pp.39-50
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    • 2024
  • The projected growth of global meat production over the next decade is attributed to rising income levels and population expansion. One potentially more pragmatic approach to mitigating the adverse externalities associated with meat production involves implementing alterations to the production process, such as transitioning to cultured meat, hybrid cultured meat, and meat alternatives. Cultured meat (CM) is derived from animal stem cells and undergoes a growth and division process that closely resembles the natural in vivo cellular development. CM is emerging as a widely embraced substitute for traditional protein sources, with the potential to alleviate the future strain on animalderived meat production. To date, the primary emphasis of cultured meat research and production has predominantly been around the ecological advantages and ethical considerations pertaining to animal welfare. However, there exists substantial study potential in exploring consumer preferences with respect to the texture, color, cuts, and sustainable methodologies associated with cultured meat. The potential augmentation of cultured meat's acceptance could be facilitated through the advancement of a wider range of cuts to mimic real muscle fibers. This review examines the prospective commercial trends of hybrid cultured meat. Subsequently, the present state of research pertaining to the advancement of scaffolding, coloration, and muscle fiber development in hybrid cultured meat, encompassing plant-based alternatives designed to emulate authentic meat, has been deliberated. However, this discussion highlights the obstacles that have arisen in current procedures and proposes future research directions for the development of sustainable cultured meat and meat alternatives, such as plant-based meat production.

Comorbid Conditions in Persons Exposed to Ionizing Radiation and Veterans of the Soviet-Afghan War: A Cohort Study in Kazakhstan

  • Saule Sarkulova;Roza Tatayeva;Dinara Urazalina;Ekaterina Ossadchaya;Venera Rakhmetova
    • Journal of Preventive Medicine and Public Health
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    • 제57권1호
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    • pp.55-64
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    • 2024
  • Objectives: This study investigated the prevalence and characteristics of comorbid conditions in patients exposed to ionizing radiation and those who were involved in the Soviet-Afghan war. Methods: This study analyzed the frequency and spectrum of morbidity and comorbidity in patients over a long-term period (30-35 years) following exposure to ionizing radiation at the Semipalatinsk nuclear test site or the Chornobyl nuclear power plant, and among participants of the Soviet-Afghan war. A cohort study, both prospective and retrospective, was conducted on 675 patients who underwent comprehensive examinations. Results: Numerical data were analyzed using the Statistica 6 program. The results are presented as the mean±standard deviation, median, and interquartile range (25-75th percentiles). The statistical significance of between-group differences was assessed using the Student t-test and Pearson chi-square test. A p-value of less than 0.05 was considered statistically significant. We found a high prevalence of cardiovascular diseases, including hypertension (55.0%) and cardiac ischemia (32.9%); these rates exceeded the average for this age group in the general population. Conclusions: The cumulative impact of causal occupational, environmental, and ultra-high stress factors in the combat zone in participants of the Soviet-Afghan war, along with common conventional factors, contributed to the formation of a specific comorbidity structure. This necessitates a rational approach to identifying early predictors of cardiovascular events and central nervous system disorders, as well as pathognomonic clinical symptoms in this patient cohort. It also underscores the importance of selecting suitable methods and strategies for implementing treatment and prevention measures.

Abdominal Hypertension after Abdominal Plication in Postbariatric Patients: The Consequence in the Postoperative Recovery

  • Martin Morales-Olivera;Erik Hanson-Viana;Armando Rodriguez-Segura;Marco A. Rendon-Medina
    • Archives of Plastic Surgery
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    • 제50권6호
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    • pp.535-540
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    • 2023
  • Background Abdominoplasty with abdominal plication increases intra-abdominal pressure (IAP) and has been previously associated with limited diaphragmatic excursion and respiratory dysfunctions. Many factors found in abdominoplasties and among postbariatric patients predispose them to a higher occurrence. This study aims to evaluate the impact of abdominal plication among postbariatric patients, assess whether the plication increases their IAP, and analyze how these IAP correlate to their postoperative outcome. Methods This prospective study was performed on all patients who underwent circumferential Fleur-De-Lis abdominoplasty. For this intended study, the IAP was measured by an intravesical minimally invasive approach in three stages: after the initiation of general anesthesia, after a 10-cm abdominal wall plication and skin closure, and 24 hours after the procedure. Results We included 46 patients, of which 41 were female and 5 were male. Before the bariatric procedure, these patients had an average maximum weight of 121.4 kg and an average maximum body mass index of 45.78 kg/m2; 7 were grade I obese patients, 10 were grade II, and 29 were grade III. Only three patients were operated on with a gastric sleeve and 43 with gastric bypass. We presented six patients with transitory intra-abdominal hypertension in the first 24 hours, all of them from the grade I obesity group, the highest presented was 14.3 mm Hg. We presented 15% (7/46) of complication rates, which were only four seroma and five dehiscence; two patients presented both seroma and wound dehiscence. Conclusion Performing a 10-cm abdominal wall plication or greater represents a higher risk for intra-abdominal hypertension, slower general recovery, and possibly higher complication rate in patients who presented a lower degree of obesity (grade I) at the moment of the bariatric surgery.

Coping Mechanisms Utilized by Individuals With Drug Addiction in Overcoming Challenges During the Recovery Process: A Qualitative Meta-synthesis

  • Agus Setiawan;Junaiti Sahar;Budi Santoso;Muchtaruddin Mansyur;Syamikar Baridwan Syamsir
    • Journal of Preventive Medicine and Public Health
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    • 제57권3호
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    • pp.197-211
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    • 2024
  • Objectives: Recovery from drug addiction often poses challenges for the recovering person. The coping mechanisms employed by these individuals to resist temptations and manage stress play a key role in the healing process. This study was conducted to explore the coping strategies or techniques that individuals with addiction use to handle stress and temptation while undergoing treatment. Methods: A qualitative meta-synthesis approach was utilized to critically evaluate relevant qualitative research. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines were used for article selection, with these standards applied to 4 academic databases: Scopus, PubMed, ProQuest, and CINAHL. The present review included studies published between 2014 and 2023, selected based on pre-established inclusion criteria. The quality of the studies was assessed using the Critical Appraisal Skills Programme Qualitative Studies Checklist. This review was registered with the International Prospective Register of Systematic Reviews (PROSPERO) under the registration number CRD42024497789. Results: The analysis of 13 qualifying qualitative articles revealed 5 major themes illustrating the coping mechanisms employed in the pursuit of recovery by individuals who use drugs. These themes include seeking social support, as well as psychological coping strategies, spiritual experiences, professional interventions, and the enhancement of awareness. Conclusions: Among individuals with drug addiction, coping mechanisms are crucial for resisting stress and temptations throughout the recovery process. Healthcare professionals, as medical specialists, can establish more thorough and effective plans to support these patients on their path to recovery.

주의력결핍 ${\cdot}$ 과잉운동장애아의 기질적 특성 (TEMPERAMENTAL CHARACTERISTICS OF ATTENTION DEFICIT HYPERACTIVITY DISORDER)

  • 조수철;김동현;김자성
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • 제4권1호
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    • pp.114-123
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    • 1993
  • 주의력결핍 ${\cdot}$ 과잉운동장애아의 걸음마기의 기질적 특성을 알아보기 위하여, 걸음마기질 평가척도를 사용하여 기타질환 및 대조군과 비교하여 다음과 같은 결과를 얻었다. 1) 주의력결핍 ${\cdot}$ 과잉운동장애군과 대조군이 차이가 있었던 범주는 ‘활동수준’, ‘주기성’, ‘접근성’, ‘적응성’, ‘반응강도’, ‘주의지속성’, ‘감감역치’였다. 2) 주의력결핍 ${\cdot}$ 과잉운동장애군 및 기타 질환군이 대조군과 차이가 있었던 범주는 ‘적응성’과 ‘주의지속성’이었다. 3) 주의력결핍 ${\cdot}$ 과잉운동장애군이 기타 질환군 및 대조군과 차이가 있었던 범주는 ‘활동수준’과 ‘접근성’이었다. 4) 전체점수는 주의력결핍 ${\cdot}$ 과잉운동장애군 및 기타질환군이 대조군과 의미있는 차이를 보였다. 5) 걸음마기 기질평가척도를 사용한 주의력결핍 ${\cdot}$ 과잉운동장애의 판별력은 84.3%였다. 본 연구에서 주의력결핍 ${\cdot}$ 과잉운동장애는 걸음마기의 기질상 특징적인 모습을 가지고 있다는 결과를 얻었다. 향후 걸음마기의 기질상의 특성과 주의력결핍 ${\cdot}$ 과잉운동장애와의 관계에 대한 전향적 연구(prospective study) 및 다른 질환과의 관계를 알아보는 연구가 필요할 것이다.

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