• 제목/요약/키워드: Prophylaxis

검색결과 368건 처리시간 0.026초

신경작용제 해독제의 약리기전 및 연구개발 (Investigation of the Pharmacological Mechanisms and the R&D of Medical Countermeasures Against Nerve Agent Poisoning)

  • 조영
    • 한국군사과학기술학회지
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    • 제14권5호
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    • pp.920-931
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    • 2011
  • Nerve agents are irreversible inhibitors of the cholinesterase enzyme. Exposure causes a progression of toxic signs, including hypersecretions, fasciculations, tremor, convulsions, respiratory distress, epileptiform seizures, brain injuries and death. A combined regimen of prophylaxis and therapy is the most effective medical countermeasure for dealing with the threat of nerve agent poisoning to military personnel. In this paper, the author investigated the updated technologies regarding various pre- and post-treatment drugs for nerve agents detoxification which are under development in several countries including Korea. Some characteristics of active ingredients in the formulations of drugs, their action mechanisms, and effectiveness were analyzed. Additionally, part of experimental data on the transdermal patch studied in ADD using beagle dogs was introduced.

Aortopulmonary Fistula Presenting without an Endoleak after Thoracic Endovascular Aortic Repair

  • Sica, Giacomo;Rea, Gaetano;Bocchini, Giorgio;Lombardi, Romilda;Muto, Massimo;Valente, Tullio
    • Journal of Chest Surgery
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    • 제50권4호
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    • pp.287-290
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    • 2017
  • Herein, we report the case of a 60-year-old man, a smoker with a history of arterial hypertension and diabetes mellitus. After computed tomography (CT) for an episode of hemoptysis, the patient underwent elective thoracic endovascular aortic repair (TEVAR) because of a degenerative aneurysm of the descending thoracic aorta. The area of perianeurysmal pulmonary atelectasis reported on the CT scan was not considered. Three months later, he developed an aortopulmonary fistula without endoleaks. Although TEVAR is a relatively safe procedure, no detail should be overlooked in the preoperative evaluation in order to avoid life-threatening complications. Further, the effectiveness and modality of prolonged antibiotic prophylaxis and/or preoperative respiratory physiotherapy should be assessed in such cases.

마르코프 과정을 이용한 결핵 관리 특성에 관한 연구 (A Study on the Characteristics of Tuberculosis Control System Using Markov Processes)

  • 정형환;주수원;김해재
    • 대한의용생체공학회:의공학회지
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    • 제9권2호
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    • pp.159-164
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    • 1988
  • This thesis investigates the Quantitative aspect of epidemic phenomena utilizing the analytical method of discrete time systeMs based on the theory of Markov processes. In particular, the pattern on the epidemic character of turberculosis controlled by prophylaxis and BCG vaccinatioll was analyzed by the markovian model of tuberculosis system which is derived according to the ecologic relationship between nine epidemiologic states of individuals. The quantitative aspects of the model were characterized by digital computer simulations.

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Endoscopic treatment of vesicoureteral reflux in pediatric patients

  • Kim, Jong Wook;Oh, Mi Mi
    • Clinical and Experimental Pediatrics
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    • 제56권4호
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    • pp.145-150
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    • 2013
  • Endoscopic treatment is a minimally invasive treatment for managing patients with vesicoureteral reflux (VUR). Although several bulking agents have been used for endoscopic treatment, dextranomer/hyaluronic acid is the only bulking agent currently approved by the U.S. Food and Drug Administration for treating VUR. Endoscopic treatment of VUR has gained great popularity owing to several obvious benefits, including short operative time, short hospital stay, minimal invasiveness, high efficacy, low complication rate, and reduced cost. Initially, the success rates of endoscopic treatment have been lower than that of open antireflux surgery. However, because injection techniques have been developed, a recent study showed higher success rates of endoscopic treatment than open surgery in the treatment of patients with intermediate- and high-grade VUR. Despite the controversy surrounding its effectiveness, endoscopic treatment is considered a valuable treatment option and viable alternative to long-term antibiotic prophylaxis.

Correspondence analysis for studying association between geography and cancer

  • Song, Joon-Jin;Yu, Pingjian;Ren, Yuan;Chung, Ming-Hua
    • Journal of the Korean Data and Information Science Society
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    • 제20권5호
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    • pp.919-924
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    • 2009
  • Geographical location carries information such as demography, local economy, environment, and life styles, which could be the sources of cancer occurrence. Analyzing geographical location associated with cancer occurrence can be instructive to physicians, patients, and health administrators regarding resource allocation, expenditures, prophylaxis and treatments. In this paper, we explored the correspondence relationship between geographical locations and mortality rates of the cancers using correspondence analysis and illustrated the approach with the mortality rates of the top 10 cancers in the 75 counties in Arkansas from 2001 to 2005. Geographical variations with respect to the mortality rates of cancers are evaluated across Arkansas counties. Based on the contingency table, correspondence analysis model is developed and the simple indices which indicate the degree to which the regions and the cancers affect each other are calculated. Quantitative results are visualized and mapped in two-dimensional graphs.

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Pharmacological classification of herbal anti-asthmatics

  • Goyal, Bhoomika R;Agrawal, Babita B;Goyal, Ramesh K;Mehta, Anita A
    • Advances in Traditional Medicine
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    • 제7권1호
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    • pp.11-25
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    • 2007
  • Bronchial asthma is a major public health problem worldwide and the morbidity and mortality of asthma have increased in last few decades. There is high prevalence of usage of alternative traditional system of medicines for the treatment of asthma. Large numbers of medicinal plant preparations have been reported to possess anti-asthmatic effects. Plant cells are now considered to be the chemical factories synthesizing a large variety of chemical compounds. Further, Ayurvedic system of medicine has an elaborate description of asthma from the earliest times describing it as 'Shwasa' meaning disease pertaining to breathing. This review classifies the antiasthmatics herbs based on the possible mechanism of action reported. Thus, these plants can be used to obtain a polyherbal formulation which contains various herbs acting at particular sites of the pathophysiological cascade of asthma for prophylaxis as well as for the treatment of asthma.

Comparative Analysis of Dental Hygiene Course Students' NCS Learning Goals before and after NCS Class

  • Woo, Hee-Sun
    • 한국컴퓨터정보학회논문지
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    • 제23권3호
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    • pp.79-84
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    • 2018
  • The government developed National Competency Standards and expands field friendly education for innovation of industrial field based education training. NCS is the national level of standards that the government systemized knowledge, skills and attitudes required to work in industrial fields by each industry and each level. This study was intended to research NCS education contents of an introduction of dental hygienics, which is a basic major subject among subjects of dental hygiene course, to present learning goals accordingly, and to be used as a basic resource of NCS field oriented classes of dental hygienists through the comparison before and after. In case of the dental hygiene course, dental hygienists are performing important core tasks as clinicians at dental offices. Therefore, such comprehensive and professional performance abilities as scaling, oral prophylaxis and oral health education are required at the fields. The education process and education contents for this should be researched continuously.

임상구강위생 교육과정의 개발 방향 (Developing a Integrated Curriculum for a Clinical Dental Hygiene)

  • 조영식;이수영
    • 치위생과학회지
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    • 제5권1호
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    • pp.33-38
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    • 2005
  • The objective of this research was to evaluate a curriculum for dental hygiene program, and to develop a clinical dental hygiene course. Learning objectives of dental hygiene program was used as the measure of courses related to clinical dental hygiene. Dental hygiene process is now recognized as a standard of education and practice of clinical dental hygiene. This study demonstrated that we have to integrate oral prophylaxis and preventive dentistry based on dental hygiene process for clinical dental hygiene education curriculum. And the results indicate that competency in comprehensive dental hygiene care is a priority for dental hygiene program.

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Nanovesicles: Diagnostic and Therapeutic Tools in Nanoscale Medicine

  • Kim, Minji;Kim, Moonjeong;Kim, Kwang-sun
    • Applied Science and Convergence Technology
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    • 제25권6호
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    • pp.103-107
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    • 2016
  • The use of nanovesicles (NVs) has contributed to nanotechnology in the development of new concept medicine to compete with diseases of deleterious and infectious to human health. Due to their properties of size, morphology, and biocompatibility NVs have great impact on public health especially in the development of new therapeutic and prophylaxis approaches in addition to the device for biosensors to diagnose human diseases. Recent data also strongly suggest that NVs are regarded as innovative materials in developing for vaccines and diagnostic tools. In this review, we focus on the basic concepts and recent applications of NVs to utilize or engineer them as therapeutic materials.

구취의 심도에 따른 치료 효과에 대한 비교 연구 (Treatment Efficacy on Oral Malodor according to Pre-treatment Volatile Sulfur Compound Level)

  • 이상구;고홍섭;이승우
    • Journal of Oral Medicine and Pain
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    • 제23권3호
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    • pp.263-270
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    • 1998
  • Considering various factors contributing oral malodor, the accurate prediction of prognosis is very important to both clinician and patients. The present study has been performed to invetigate the relationship between treatment effeicacy and pre-treatment volatile sulfur compounds (VSC) level. Ninety patients were divided into three groups, A(<150ppb), B(150< <200ppb), and C(>200ppb) groups, according to pre-treatment VSC level detected by Halimeter, and each group included 30 patients. Routine therapeutic measures for oral were provided to each patient which consisted of oral prophylaxis, tooth brushing and flossing instruction, tongue scraping by proper device, and gargling of 0.25% ZnCl2 Solution. The group with high pre-treatment VSC level (>150ppb) showed significant reduction of VSC level at 1 and 3 weeks after. However, the group with low pre-treatment VSC level (<150ppb) did not show any significant reduction during the experimental periods. Collectively, the results suggested that patients with high pre-treatment VSC level show better prognosis.

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