• 제목/요약/키워드: Promising Alternative Technology

검색결과 204건 처리시간 0.024초

Optical Stimulation and Pacing of the Embryonic Chicken Heart via Thulium Laser Irradiation

  • Chung, Hong;Chung, Euiheon
    • Current Optics and Photonics
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    • 제3권1호
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    • pp.1-7
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    • 2019
  • Optical stimulation provides a promising alternative to electrical stimulation to selectively modulate tissue. However, developing noninvasive techniques to directly stimulate excitable tissue without introducing genetic modifications and minimizing cellular stress remains an ongoing challenge. Infrared (IR) light has been used to achieve optical pacing for electrophysiological studies in embryonic quail and mammalian hearts. Here, we demonstrate optical stimulation and pacing of the embryonic chicken heart using a pulsed infrared thulium laser with a wavelength of 1927 nm. By recording stereomicroscope outputs and quantifying heart rates and movements through video processing, we found that heart rate increases instantly following irradiation with a large spot size and high radiant exposure. Targeting the atrium using a smaller spot size and lower radiant exposure achieved pacing, as the heart rate synchronized with the laser to 2 Hz. This study demonstrates the viability of using the 1927 nm thulium laser for cardiac stimulation and optical pacing, expanding the optical parameters and IR lasers that can be used to modulate cardiac dynamics.

CNG 승용 자동차의 배출가스 특성에 관한 실험적 연구 (Experimental Study of Emission Characteristics for CNG Passenger Car)

  • 김현준;이호길
    • 한국가스학회지
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    • 제19권6호
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    • pp.34-39
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    • 2015
  • 최근 차량용 에너지의 소비는 대부분 화석연료로부터 사용된다. 기존 화석 연료를 사용하는 자동차보다 친환경적이며 저렴하고 재생이 가능한 연료의 요구증대로 대체연료 자동차산업이 강조되고 있다. 오늘날 고옥탄가와 높은 자기발화온도 특징을 가지고 있는 천연가스는 저렴한 비용, 기존 화석연료보다 풍부한 매장으로 기존 스파크 점화엔진인 가솔린엔진의 대체에너지로 간주되고 있다. 본 연구는 기존 2리터 가솔린 엔진에 CNG 가스 분사시스템을 장착하여 전소 및 혼소 연료분사시스템을 설치하였다. 또한 CNG전소 및 가솔린/CNG 혼소차량의 ECU 제어전략을 최적화 하였다. 혼소차량에 대하여 NEDC모드 주행결과 가솔린 차량 대비 혼소차량의 CO2 저감율을 16%확인하였다. 또한 CO와 HC의 배기가스 배출량은 가솔린 차량과 동등한 수준을 확보하였다. 하지만 NOx의 배기가스 배출수준은 증가된 현상을 확인할 수 있었다.

Screening of toxic potential of graphene family nanomaterials using in vitro and alternative in vivo toxicity testing systems

  • Chatterjee, Nivedita;Yang, Ji Su;Park, Kwangsik;Oh, Seung Min;Park, Jeonggue;Choi, Jinhee
    • Environmental Analysis Health and Toxicology
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    • 제30권
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    • pp.7.1-7.7
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    • 2015
  • Objectives The widely promising applications of graphene nanomaterials raise considerable concerns regarding their environmental and human health risk assessment. The aim of the current study was to evaluate the toxicity profiling of graphene family nanano-materials (GFNs) in alternative in vitro and in vivo toxicity testing models. Methods The GFNs used in this study are graphene nanoplatelets ([GNPs]-pristine, carboxylate [COOH] and amide [$NH_2$]) and graphene oxides (single layer [SLGO] and few layers [FLGO]). The human bronchial epithelial cells (Beas2B cells) as in vitro system and the nematode Caenorhabditis elegans as in vivo system were used to profile the toxicity response of GFNs. Cytotoxicity assays, colony formation assay for cellular toxicity and reproduction potentiality in C. elegans were used as end points to evaluate the GFNs' toxicity. Results In general, GNPs exhibited higher toxicity than GOs in Beas2B cells, and among the GNPs the order of toxicity was pristine > $NH_2$ > COOH. Although the order of toxicity of the GNPs was maintained in C. elegans reproductive toxicity, but GOs were found to be more toxic in the worms than GNPs. In both systems, SLGO exhibited profoundly greater dose dependency than FLGO. The possible reason of their differential toxicity lay in their distinctive physicochemical characteristics and agglomeration behavior in the exposure media. Conclusions The present study revealed that the toxicity of GFNs is dependent on the graphene nanomaterial's physical forms, surface functionalizations, number of layers, dose, time of exposure and obviously, on the alternative model systems used for toxicity assessment.

3D 프린팅 기술의 의료기기 수리 적용에 대한 국내 규제 이슈 및 기술적 적합성 평가 (Regulation Issues in Korea and Technical Feasibility Evaluation of 3D Printing-Based Medical Device Repair)

  • 윤성욱;남경원
    • 대한의용생체공학회:의공학회지
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    • 제41권2호
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    • pp.75-83
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    • 2020
  • In large-scale hospitals, the department of biomedical engineering should always provide quick repair service for damaged medical devices to guarantee continuous patient treatment. However, in actual circumstances, there are so many time-consuming issues that delays device repair for weeks or even months; therefore, it is required to prepare alternative ways for quick repair service. In this study, we first mentioned about the regulation issues in Korea about the 3D printing-based medical device repair, and then introduced the results of our preliminary study that evaluated the feasibility of 3D printing-based medical device repair before real-field application. Results of the study demonstrated that, in all of the 23 cases, parts for repair that were manufactured by 3D-printing were successfully fixed and connected to the main body of the original device, and showed sufficient rigidity for protecting internal parts of the device. Considering the experimental results, medical device repair by applying 3D printing technology can be a promising alternative in cases when regular repair process is not available or takes too much time.

IEC 61800 기반 파워 드라이버 시스템을 위한 EtherCAT 슬레이브 모듈 구현 (Implementation of EtherCAT Slave Module for IEC 61800-based Power Driver System)

  • 김만호;박지훈;이석;이경창
    • 제어로봇시스템학회논문지
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    • 제17권2호
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    • pp.176-182
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    • 2011
  • Industrial network, often referred to as fieldbus, becomes an indispensable component for intelligent manufacturing systems. Thus, in order to satisfy the real-time requirements of field devices such as sensors, actuators, and controllers, numerous fieldbus protocols have been developed. But, the application of fieldbus has been limited due to the high cost of hardware and the difficulty in interfacing with multi-vendor products. As an alternative to fieldbus, the Ethernet (IEEE 802.3) technology is being adapted to the industrial environment. However, the crucial technical obstacle of Ethernet is its non-deterministic behavior that cannot satisfy the real-time requirements. Recently, the EtherCAT protocol becomes a very promising alternative for real-time industrial application due to the elimination of uncertainties in Ethernet. This paper focuses on the implementation of the IEC 61800 based real-time EtherCAT network for multi-axis smart driver. To demonstrate the feasibility of the implemented EtherCAT slave module, its synchronization performance is evaluated on the experimental EtherCAT testbed with a single axis smart driver.

Improved evaluation of ring tensile test ductility applied to neutron irradiated 42XNM tubes in the temperature range of (500-1100)℃

  • Gurovich, B.A.;Frolov, A.S.;Fedotov, I.V.
    • Nuclear Engineering and Technology
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    • 제52권6호
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    • pp.1213-1221
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    • 2020
  • Chromium-nickel alloy 42XNM (XHM-1, Bochvalloy) is considered as a promising material for future generations of nuclear reactors, primarily as a material for the fuel elements shells in the development of accident tolerant fuel. However, as with most nickel-based alloys, 42ХNМ is characterized by a sharp decrease in plastic properties in the temperature range of (500-900)℃. This effect is enhanced by neutron irradiation. Preliminary tests of ring samples of 42XNM alloy (after irradiation as a part of the VVER-1000 control system) in the temperature range of ductility failure showed that the standard technique for processing tensile diagrams does not allow to evaluate the plastic properties correctly at low strains. Therefore, in this work, the alternative method for testing ring samples from materials with low plastic characteristics was developed. It was shown that the minimum value of the permanent strain of the irradiated 42XNM alloy in the temperature range of (500-1100)℃, determined by the alternative method, was ~1.6% at 750 ℃.

고온형 연료전지 기반 통합형 발전시스템 - 연구개발 동향 고찰 - (Integrated Power Generation Systems Based on High Temperature Fuel Cells - A Review of Research and Development Status -)

  • 김동섭;박성구
    • 대한기계학회논문집B
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    • 제33권5호
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    • pp.299-310
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    • 2009
  • Fuel cells are expected to be promising future power sources in both aspects of thermal efficiency and environmental friendliness. Accordingly, worldwide research and development efforts have been enormously increasing recently in various applications such as power plants, transportation and portable power sources. Among others, high temperature fuel cells, such as solid oxide fuel cells and molten carbonate fuel cells, are suitable for electric power plants. Moreover, their high operating temperature is quite appropriate to construct further advanced integrated systems. This paper reviews recent literatures on research and development of integrated power generation systems based on high temperature fuel cells. Research and development efforts are summarized in the area of fuel cell/ gas turbine hybrid systems, application of carbon capture technology to fuel cell systems, integration of coal gasification with fuel cells, and the use of alternative fuels.

PM6:Y6를 기반으로 한 삼중 혼합 유기 태양전지 동향 (Ternary Blend Organic Solar Cells Trends based on PM6:Y6)

  • 윤동환;신광용;정윤혜;하영우;김기환
    • Current Photovoltaic Research
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    • 제11권3호
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    • pp.79-86
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    • 2023
  • As we strive to mitigate the environmental impact caused by the use of fossil fuels, the exploration of alternative energy sources has gained significant attention. Solar energy, in particular, has emerged as a promising solution due to its eco-friendly nature and virtually limitless availability. Among the various types of solar cells that harness this abundant energy source, organic solar cells have garnered considerable interest. Organic solar cells feature a photo-active layer composed of organic semiconductors, offering a range of appealing advantages such as cost-effectiveness, flexibility, translucency, and the ability to produce customizable colors. However, the commercialization of organic solar cells has been impeded by certain challenges, notably their relatively low efficiency and stability. To overcome these obstacles and pave the way for wider adoption, researchers have been exploring innovative approaches, including the implementation of ternary blend organic solar cells. This strategy involves introducing a third component into the photo-active layer alongside the organic semiconductors, with the aim of enhancing the overall performance of the solar cell. In this paper, we delve into the issues associated with organic solar cells and focus on one potential solution: ternary blend organic solar cells. Specifically, we examine the application of this approach to PM6:Y6, which stands as one of the most popular combinations of organic semiconductors. By investigating the potential of ternary blends, particularly utilizing PM6:Y6, we aim to accelerate the commercialization of organic solar cells.

Multi-Valued Logic Device Technology; Overview, Status, and Its Future for Peta-Scale Information Density

  • Kim, Kyung Rok;Jeong, Jae Won;Choi, Young-Eun;Kim, Woo-Seok;Chang, Jiwon
    • Journal of Semiconductor Engineering
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    • 제1권1호
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    • pp.57-63
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    • 2020
  • Complementary metal-oxide-semiconductor (CMOS) technology is now facing a power scaling limit to increase integration density. Since 1970s, multi-valued logic (MVL) has been considered as promising alternative to resolve power scaling challenge for increasing information density up to peta-scale level by reducing the system complexity. Over the past several decades, however, a power-scalable and mass-producible MVL technology has been absent so that MVL circuit and system implementation have been delayed. Recently, compact MVL device researches incorporating multiple-switching characteristics in a single device such as 2D heterojunction-based negative-differential resistance (NDR)/transconductance (NDT) devices and quantum-dot/superlattices-based constant intermediate current have been actively performed. Meanwhile, wafer-scale, energy-efficient and variation-tolerant ternary-CMOS (T-CMOS) technology has been demonstrated through commercial foundry. In this review paper, an overview for MVL development history including recent studies will be presented. Then, the status and its future research direction of MVL technology will be discussed focusing on the T-CMOS technology for peta-scale information processing in semiconductor chip.

Industrial Applications of Rumen Microbes - Review -

  • Cheng, K.J.;Lee, S.S.;Bae, H.D.;Ha, J.K.
    • Asian-Australasian Journal of Animal Sciences
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    • 제12권1호
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    • pp.84-92
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    • 1999
  • The rumen microbial ecosystem is coming to be recognized as a rich alternative source of genes for industrially useful enzymes. Recent advances in biotechnology are enabling development of novel strategies for effective delivery and enhancement of these gene products. One particularly promising avenue for industrial application of rumen enzymes is as feed supplements for nonruminant and ruminant animal diets. Increasing competition in the livestock industry has forced producers to cut costs by adopting new technologies aimed at increasing production efficiency. Cellulases, xylanases, ${\beta}$-glucanases, pectinases, and phytases have been shown to increase the efficiency of feedstuff utilization (e.g., degradation of cellulose, xylan and ${\beta}$-glucan) and to decrease pollutants (e.g., phytic acid). These enzymes enhance the availability of feed components to the animal and eliminate some of their naturally occurring antinutritional effects. In the past, the cost and inconvenience of enzyme production and delivery has hampered widespread application of this promising technology. Over the last decade, however, advances in recombinant DNA technology have significantly improved microbial production systems. Novel strategies for delivery and enhancement of genes and gene products from the rumen include expression of seed proteins, oleosin proteins in canola and transgenic animals secreting digestive enzymes from the pancreas. Thus, the biotechnological framework is in place to achieve substantial improvements in animal production through enzyme supplementation. On the other hand, the rumen ecosystem provides ongoing enrichment and natural selection of microbes adapted to specific conditions, and represents a virtually untapped resource of novel products such as enzymes, detoxificants and antibiotics.