• Korean Journal of Food Science and Technology
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• v.43 no.2
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• pp.230-234
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• 2011

According to the Codex committee, the maximum allowable level for lead in fruits is 0.1 mg/kg. This survey was conducted as a surveillance program following the establishment of safety guideline for fruits in Korea. Concentrations of lead (Pb), cadmium (Cd), arsenic (As) and mercury (Hg) were measured in 927 samples using a ICP-MS and a mercury analyzer. The recoveries of microwave digestion method were 86.0-110.4% for Pb, 81.0-104.0% for Cd and 82.0-104.7% for As by standard addition method. The recovery of direct mercury analyzer was 106.5% for Hg. The average levels of Pb in ${\mu}g/kg$ were $10.0{\pm}12.8$ for apple, $8.8{\pm}10.9$ for pear, $4.1{\pm}4.4$ for persimmons, $14.9{\pm}12.3$ for mandarin, $7.1{\pm}6.5$ for orange, $3.1{\pm}3.3$ for banana, $8.8{\pm}8.9$ for kiwi, and $9.3{\pm}9.7$ for mango. The average levels of Cd in ${\mu}g/kg$ were $0.4{\pm}0.3$ for apple, $2.0{\pm}1.6$ for pear, $0.3{\pm}0.3$ for persimmon, $0.1{\pm}0.1$ for mandarin, $0.1{\pm}0.1$ for orange, $1.3{\pm}1.8$ for banana, $0.5{\pm}0.5$ for kiwi, and $0.7{\pm}0.6$ for mango. The average levels of As in ${\mu}g/kg$ were $2.0{\pm}2.1$ for apple, $1.2{\pm}1.3$ for pear, $1.5{\pm}1.2$ for persimmon, $0.8{\pm}0.3$ for mandarin, $1.5{\pm}0.5$ for orange, $1.8{\pm}1.2$ for banana, $1.6{\pm}1.5$ for kiwi, and $1.2{\pm}1.5$ for mango. The average levels of Hg in ${\mu}g/kg$ were $0.5{\pm}0.4$ for apple, $0.3{\pm}0.2$ for pear, $0.2{\pm}0.1$ for persimmon, $0.2{\pm}0.1$ for mandarin, $0.2{\pm}0.1$ for orange, $0.2{\pm}0.0$ for banana, $0.2{\pm}0.2$ for kiwi, and $0.6{\pm}0.2$ for mango. Based on the Korean public nutrition report 2005, these levels (or amounts) are calculated only at 0.17% for Pb, 0.013% for Cd and 0.006% for Hg of those presented in provisional tolerable weekly Intake (PTWI) which has been established by FAO/WHO. Therefore, the levels presented here are presumed to be adequately safe.

• Journal of Korean Public Health Nursing
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• v.3 no.2
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• pp.47-76
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• 1989

The objectives of this study was to analyze the major causes of decreasing utilization rate of health care institutios in pilot-project area of regional medical insurance, Kwang-hwa and Kun-wi country. After the implementation of medical insurance, utilization rate of health institutions turned out' to be lower than it was estimated, when the pilot-project of regional medical insurance was planned. It might be due to changes in inhabitant's behavioral attitude toward medical insurance. So this study was made to find measures for financial stability by increasing utilization rate of health care institutions and to be available for basic demand-supply program of medical care. The hypothesis of this study was as follows; First. there is difference in understanding health care institutions between Kun-wi and Kwang-hwa. Second. respondesnts of inquiry survey have exact knowledge of their past experience of treatment taken prior to enforcement of medical insurance, Questionaire survey was made as to each 700 household among total 11, 884 households in Kun-wi and 20,919 households in Kwang-hwa. In case of Kun-wi, 70% of inquired households (491) gave their answers. In Kwang-hwa, the number was 560 households (80% of inquireds). Dollected data was processed and analyzed by way of using SPSS batch system. To evaluate facto rs distribution aspects of data and to make comparison between two area, percentage and $X^2$ distribution were applied. The results were as follows; L The utilization rate of health care institutions in Kun-wi and Kwang-hwa was lower than it was estimated. when pilot-project of medical insurance was planned. 2. Prior to the implementation of medical insurance. inhabitants in two area chose the medical institutions considering such factors. First was medical care fee cheap. second in habitant's residence, Third was the institutions conveniently easy of access. 3. After the implementation of medical insurance. 26.1% of inqurieds in Kun-wi and 41.6% in Kwang-hwa, changed medical institutions. In case of Kwn-wi, from health care institution (p 0.05), and in case of Kwang-hwa, vice versa, from general medical institutions to health care institutions. 4. Evaluation by factors were made such as follows. Inquired gave high marks to following facts: In case of Kun-wi, general medical institutions were difficult of access and relation between patients: was not friendly, but burden of medical expenditure was light. Effects of treatment and facilities was good. In case of Kwang-hwa, inquired gave high evaluation marks to the follow ing facts; facilities of medical institutions was not good, but the burden of medical expenditure was light. 5. After the implementation of medical insurance, the services was evaluated as good, but inquired hopec for lessening the burden of medical expenditure. 6. In case of exact understanding of cost-sharing, the evaluation rate in Kwang-hwa was higher than that of Kun-wi (p < 0.005). And positive attitude toward necessity of medical insurance was also good in Kwang-hwa (p < 0.05). 7. In case of inquired's attitude toward medical institutions, Kwang-hwa showed positive response (p < 0.05) 8. In the case of comparison between general medical institution and health care institution, two area showed similar positive response; medical manpower, facilities of medical institutions and effest: of treatement was good. 9. In comprehensive evaluation of benefit-service; the general medical institution's positiveness was higher than that of health care institutions in Kun-wi. But in Kwang-hwa vice-versa. 10. If the medical expenditure of general medical institution and health care institutions was equal 77% of inquireds in Kun-wi and 59.1% in Kwang-hwa answered that they chose general medical insurance. Considering results above mentioned, the conclusion of this study was made as follows. 1. In Kwang-hwa county, where the understanding of health care institutions's was good, the utilization's of health care institutions was shown high. Therefore, in case of Kwang-hwa, betterment: should be made to induce increasing utilization rate for negative factors of health care institutions. 2. In case of Kun-wi, where the understanding of health care institutions was on the decrease, measures for changing such negative factors should be taken by way of strengthening public relations. And cases of Kwang-hwa should also be studied. 3. On the side of financial stabilization and establishing health care delivery system, primary health care should be available. Therefore, the major cause of inhabitant's avoiding health care institutions should be known. And measures for activating that institutions have to be taken. So, the facilities of health care institution have to be improved up to the level of clinic. And supportive measures for securing equipment and improving health care services should also be taken. It is necessary that strategy for public relations should be employed with policy considerations and supports.

• Journal of Korean Public Health Nursing
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• v.12 no.1
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• pp.116-131
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• 1998

This study was undertaken to obtain the menstrual patterns and menstrual discomforts in women university students. For the data collection, self-administered questionnaire survey was made from December 10, 1996 to January 20, 1997 among the 180 women university students in Seoul. The resultant data were processed by SAS program for frequency, proportion, and chi-square test. The results of this study are as follows ; 1) The mean age of the subjects was 20.6 years old. The mean height was 162cm and weight was 52.3Kg. $26.9\%$ of the subjects responded that they had experienced the unbalanced diet, $56\%$ the irregular meal, $39.6\%$intermittent dizziness, and $63.4\%$ the premenstrual syndrome. $53.7\%$ had feeling that skin temperature of their four extremities was 'a little lower than others'. The mean BMI(Body Mass Index) was 19.8, 'normal level' was $41.8\%$. $18.7\%$ responded that their characters were 'introspective ones'. The mean age of menache was 13.8 years old. The subjects responded that the mean number of pads they used per day during menstrual periods was 4.6 sheets. The mean duration of menstruation was 5.4 days, $10.4\%$ responded that their menstrual cycles were 'extremely regular', $44.8\%$ was 'regular', $36.6\%$ was 'a little irregular', and $8.2\%$ was 'extremely irregular'. Out of them who had experienced the dysmenorrhea, $21.3\%$ had family history of dysmenorrhea in connection with their mother and $35.0\%$ in their sisters. The mean of the first time that they experienced dysmenorrhea was 15 years old. $94\%$ of the subjects responded that they had experienced the dysmeorrhea. $47.6\%$ of the subjects responded that they experienced the dysmenorrhea 'monthly' and $52.4\%$ 'intermittently'. $53.0\%$ of them who had experienced dysmenorrhea responded that dysmenorrhea was the severest 'on the first menstrual day' and $22.4\%$ 'on the second day'. $48.8\%$ of them who had experienced dysmenorrhea responded that the most painful region was 'low abdomen'. $40\%$ of them who had experienced dysmenorrhea responded that they used 'analgesics' to soothe dysmenorrhea, $24.8\%$ used nothing, $18.4\%$ lay in their beds or slept, and $12\%$ made their 'low abdomen' warm. $70.3\%$ who had used analgesics because of dysmenorrhea took analgesics 'one or two times per month', $25.7\%$ 'intermittently', and $4.0\%$ more than 3 times per month. The analgesics which they used were 'geworin$(33.8\%)$,' 'penzal$(32.4\%)$', 'tyrenol$(18.9\%)$', and 'aspirin$(4.2\%)$'. $(47.9\%)$ of them who took analgesics because of dysmenorrhea responded that the duration of analgesics effect was '4 to 8 hours'. $15.1\%$ of them who experienced dysmenorrhea responded that they had visited the hospital. 2) The incidence of premenstrual syndrome was no significant difference according to the BMI, unbalanced diet, pattern of meal, skin temperature of four extremites, and characters. 3) The incidence of dysmenorrhea was significant difference according to the BMI, unbalanced diet, pattern of meal, skin temperature of four extremites, and characters. 4) The incidence of analgesics usage was significant difference according to the BMI, subjects with low BMI took more analgesics than those with normal BMI (p<.05). The incidence of analgesics usage was significant difference in accordance with pattern of meal. The women who had a meal regularly took more analgesics than those who had a meal irregularly(p<.05). But the incidence of analgesics usage was no significant difference in accordance with the unbalanced diet, characters, the incidence of dizziness, skin temperature of four extremities, the incidence of premenstrual syndrome.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.3
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• pp.410-422
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• 2018

This paper studies the factors that increase the sustainability of Industry-University cooperation in the current structure of domestic I-U cooperation, which is highly dependent on government support. First, we examine the extent to which the 'I-U Relationship Strength' can be explained by the cumulative 'Experiences of I-U cooperation' and 'Width of various I-U cooperation channels', and the 'I-U cooperation barrier' can be explained by the 'Difference in mutual recognition' and 'Institutional barriers' on sustainability. In addition, the factors that can lower the 'I-U cooperation barrier', such as the 'University administration's efforts' and 'Trust between I-U', are examined. The researchers examined the factors affecting the sustainability of I-U cooperation and the factors affecting 'I-U cooperation barriers' in the 'I-U cooperation technology development projects' of the Ministry of Small & Medium Venture Business and Startups with its long history of domestic I-U cooperation programs. In order to clarify the data of the research sample, a questionnaire survey of organizational units was conducted for all companies participating in the 'I-U cooperation technology development projects' of the Ministry of SMVB and Startups between 2011 and 2015, and the responses of 356 organizations were used. It was found that the greater the 'Width of the I-U cooperation channels', the higher the sustainability and that the greater the 'Institutional barriers', the lower the sustainability. However, through the 'University administration's efforts' and 'Trust between I-U', it is possible to overcome the 'I-U cooperation barrier'. Ultimately, the systematization of Industry-University-Research institute subjects is needed to realize sustainability. In other words, it is necessary to have a linkage program that can broaden the link between industry and universities, that is to broaden the scope of I-U cooperation. Moreover, it is necessary for the government to provide institutional support to promote desirable I-U cooperation policies. Finally, it is essential to change the universities' core organizations in order to improve the level of university administration services.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.3
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• pp.479-488
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• 2018

This study was conducted to investigate factors affecting low body weight of solitary elderly people by grasping the illness and health behavior of elderly living alone. Using the raw data of the community health survey from 2014, the data of 922 elderly living alone who are 65 years or older were used for the final analysis. Data were analyzed by technical analysis statistics, The Rao Scott $x^2$ test, and logistic regression analysis using the composite analysis module of the SPSS/WIN 22.0 program. The results of this study showed that elderly living alone had a high percentage of chronic diseases as well as poor health behaviors such as smoking, drinking, lack of exercise, poor eating habits, difficulties in dentistry due to dentures, and poor subjective health status. Result of logistic regression analysis the risk probability of low-weight due to gender of the elderly living alone is as follows. Risk of low body weight because of smoking was 3.004 times among occasional smokers in women and the elderly, while risk of low body weight due to walking amount is less than 3 days the possibility that the person walking is low is 1.420 times significantly higher. When feeling subjective stress, the possibility of low body weight was 2.220 times greater for male elderly and 1.282 times for female elderly. The probability of low body weight for a person with a poor subjective health level was 3.633 times for male elderly and 1.590 times for female elderly. Based on the results of this study, it is necessary to establish appropriate nursing intervention and management strategies to improve health behavior of low body weight elderly living alone. It is also necessary to conduct additional studies considering various variables such as physical, psychological, and social characteristics of low-weight elderly individuals.

• Clinical and Experimental Pediatrics
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• v.46 no.5
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• pp.440-446
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• 2003

Purpose : The genetic disturbance of galactosemia is expressed as a cellular deficiency of either galactose-1-phosphate uridyltransferase(GALT) or galactokinase(GALK) or UDP galactose 4-epimerase(GALE). To find-out the pattern of galactosemia in Korea, we retrospectively analyzed cases of galactosemia detected by neonatal screening program. Methods : We analyzed medical records of patients who visited Soonchunhyang University Hospital at age of 1 month after showing abnormalities in neonatal screening of galactosemia. For accurate diagnosis, galactose was measured by enzyme immunoassay(EIA) and fluorophotometer, also galactose-1-phosphate by fluorophotometer. Enzyme activities of GALK, GALT and GALE in RBC and galactose-1-phosphate were measured by radioisotope assay(RIA). Beutler test were done. Patients went on a lactose-free diet and follow-up tests for galactose, galactose-1-phosphate level and enzyme activity were performed. Results : 10 patients(male : 6, female : 4) were diagnosed as galactosemia. Two patients had GALK deficiency and two had GALT deficiency. Six were GALE deficient showing the largest number. In two patients with GALK deficiency, GALT and GALE activities were normal but GALK activities showed respectively reduced activity. For GALT deficiency, two patients had low GALT activity in RBC and showed genotype of Duarte 2/G(galactosemia) in DNA analysis. In one patient, GALT activity was normal. Three patients seemed to be heterozygote state of GALE deficiency according to GALE activity levels. Four patients showed GALK hyperactivity. Conclusion : GALE deficiency provided the highest number. After lactose-free diet, galactose and galactose-1-phosphate were normaly maintained. Neonatal screening on galactosemia is essential for preventing life-threatening symptoms and an accurate diagnosis is needed for finding out the type of galactosemia which is important for prognosis.

• Progress in Medical Physics
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• v.23 no.3
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• pp.145-153
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• 2012

In this study, we quantify the residual motion artifact in 4D-CT scan using the dynamic lung phantom which could simulate respiratory target motion and suggest a simple one-dimension theoretical model to explain and characterize the source of motion artifacts in 4DCT scanning. We set-up regular 1D sine motion and adjusted three level of amplitude (10, 20, 30 mm) with fixed period (4s). The 4DCT scans are acquired in helical mode and phase information provided by the belt type respiratory monitoring system. The images were sorted into ten phase bins ranging from 0% to 90%. The reconstructed images were subsequently imported into the Treatment Planning System (CorePLAN, SC&J) for target delineation using a fixed contour window and dimensions of the three targets are measured along the direction of motion. Target dimension of each phase image have same changing trend. The error is minimum at 50% phase in all case (10, 20, 30 mm) and we found that ${\Delta}S$ (target dimension change) of 10, 20 and 30 mm amplitude were 0 (0%), 0.1 (5%), 0.1 (5%) cm respectively compare to the static image of target diameter (2 cm). while the error is maximum at 30% and 80% phase ${\Delta}S$ of 10, 20 and 30 mm amplitude were 0.2 (10%), 0.7 (35%), 0.9 (45%) cm respectively. Based on these result, we try to analysis the residual motion artifact in 4D-CT scan using a simple one-dimension theoretical model and also we developed a simulation program. Our results explain the effect of residual motion on each phase target displacement and also shown that residual motion artifact was affected that the target velocity at each phase. In this study, we focus on provides a more intuitive understanding about the residual motion artifact and try to explain the relationship motion parameters of the scanner, treatment couch and tumor. In conclusion, our results could help to decide the appropriate reconstruction phase and CT parameters which reduce the residual motion artifact in 4DCT.

• Korean Journal of Psychosomatic Medicine
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• v.26 no.1
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• pp.35-43
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• 2018

Objectives : Effects of multiple trauma are complex and extend beyond core PTSD symptoms. However, few psychological instruments for trauma assessment address this issue of symptom complexity. The Trauma Symptom Checklist-40 (TSC-40) is a self-report scale that assesses wide range of symptoms associated with childhood or adult traumatic experience. The purpose of the present study was to evaluate the validity of the Korean Version of the TSC-40 in a sample of psychiatric outpatients. Methods : Data of 367 treatment-seeking patients with DSM-IV diagnoses were obtained from an outpatient department of psychiatric unit at a university hospital. The diagnoses were anxiety disorder, posttraumatic stress disorder, depressive disorder, adjustment disorder and others. Included in the psychometric data were the TSC-40, the Life events checklist, the Impact of Event Scale-Revised, the Zung's Self-report Depression Scale, and the Zung's Self-report Anxiety Scale. Cronbach's ${\alpha}$ for internal consistency were calculated. Convergent and concurrent validity was approached with correlation between the TSC-40 and other scales (PTSD, anxiety and depression). Results : Exploratory factor analysis of the Korean Version of TSC-40 extracted seven-factor structure accounted for 59.55% of total variance that was contextually similar to a six-factor structure and five-factor structure of the original English version. The Korean Version of TSC-40 demonstrated a high level of internal consistency. (Cronbach's ${\alpha}=0.94$) and good concurrent and convergent validity with another PTSD scale and anxiety and depression scales. Conclusions : Excellent construct validity of The Korean Version of TSC-40 was proved in this study. And subtle difference in the factor structure may reflect the cultural issues and the sample characteristics such as heterogeneous clinical population (including non-trauma related disorders) and outpatient status. Overall, this study demonstrated that the Korean version of TSC-40 is psychometrically sound and can be used for Korean clinical population.

• Reproductive and Developmental Biology
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• v.28 no.3
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• pp.203-207
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• 2004

The transgenic mice carrying human Interleukin-10 (hIL-10) gene in conjunction with bovine (3 -casein promoter express hIL-10 in milk during lactation. In this study, stability of germ line transmission and expression of hIL-10 transgene integrated into host chromosome were monitored up to generation F8 of transgenic mice. When male mouse of generation F8 was crossbred with normal females, approximately half of offspring (50.9±5.8%) were identified as transgenic mice. Generation F9 to F15 mice also showed similar transmission rates (66.0±20.1%, 61.5±16.7%, 41.1±8.4%, 40.7±20.3%, 61.3±10.8%, 49.2±18.8% and 43.8±25.9%, respectively), implying that hIL-10 transgene can be transmitted stably up to long term generation in the transgenic mice. Expression levels of human IL-10 from milk of generation F9 to F14 mice were 3.6± 1.2 mg/ml, 4.2±0.9 mg/ml, 5.7±1.5 mg/ml, 6.3±3.5 mg/ml, 6.8±4.5 mg/ml and 6.8±3.1 mg/ml, respectively, which was showed high-level expression compared with that of generation F1 (1.6 mg/ml) mice. In conclusion, our results suggest that transgenic mice can be continuously passed their transgenes to the progeny through the breeding program with the same productivity of human IL-10 protein in their milk.

• Current Research on Agriculture and Life Sciences
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• v.3
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• pp.129-150
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• 1985

The present investigation was conducted to provide a systematic approach necessary to establish an integrated insect pest management program of barley in Korea. Some ecological surveys on insect pests of barley have been undertaken at the field of Experimental Station, Ky$\check{o}$ngbuk Provincial Office of Rural Development as a fixed point survey area, and at 23 localities for round survey throughout southern and central Korea from 1983 to 1984. Previously known insects injurious to barley in Korea were revised and the population dynamics of 10 dominant harmful species were analyzed according to either 24 localities or 25 cultivars respectively by using several sampling methods of net sweeping, black light traps, yellow water pan traps and visual counting. As the results, a total of 94 species belonging to 77 genera under 32 families are known to be injurious to barley, among them 20 species are newly added here. In the population density level, the dominant species were disclosed as Laodelphax striatellus (43.1 %), Macrosiphum avenae(27.0 %), Rhopalosiphum padi(6.5 %), R. maidis(5.4 %), Psammolettix strialus(2.7 %), Chlorops oryzae(2.2 %), Agromyza albipennis(2.1 %) Phyllotreta nemorum(1.4 %), Chaetoenema cylindrica(1.0 %), Dolycoris baccarum(1.0 %) in order. For the general abundance of major insect pests, it was highest in the cultivar P'aldal whereas lowest in Milyang #22. There were tendencies that Psammotettix striatus, Dolycoris baccarum, Phyllotreta nemorum and Chaetocnema cylindrica represented a maximum increase in the beginning of June, while Chlorops oryzae and Agromyza albipennis showed in the middle of May but aphids were in the end of May. In the dominance of natural enemies, Nabis stenoferus occupied 21.4 % and Propylaea japonica 9.6 %.