• Title/Summary/Keyword: Program Design

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Improvement of Pregnancy Rates by Coculture of Human Embryos with Cumulus Cells in Glucose and Phosphate Free M-TALP Media (Glucose와 Phosphate가 제거된 M-TALP 배지에서의 난구세포 공배양에 의한 임신율 향상에 관한 연구)

  • Chung, B.S.;Chang, W.H.;Lee, M.H.;Kim, J.Y.;Bang, J.H.;Kim, K.H.;Suh, T.K.
    • Clinical and Experimental Reproductive Medicine
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    • v.26 no.1
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    • pp.75-81
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    • 1999
  • The beneficial effect of glucose and phosphate ions in culture medium on the development of human embryos in vitro has not been fully elucidated. The purpose of this study was to evaluate the influence of fertilization and culture of embryos in glucose/phosphate-free m-TALP medium on pregnancy rates in IVF-ET program. The patients in 244 IVF-ET cycles received GnRH agonist + HMG regimens. A does of 10,000 IU HCG was administered when two or more dominent follicles reached 18mm in diameter. Thirty-six hours after HCG, oocytes were recovered transvaginally using ultrasound guidance. Aspirated oocytes were matured for 4 to 6 h in TCM-199 supplemented with 10% follicular fluid (FF). Insemination was carried out with 50,000 motile spermatozoa in TCM-199 + 10% FF or m-TALP + 5% FF + 5% fetal cord serum (FCS) according to experimental design. After 6 h, oocytes were washed 3 to 4 times and cultured in each fresh medium. After 20 h, oocytes were freed from cumulus/corona cells and examined for the presence of pronuclei. Fertilized oocytes were transferred into each co-culture drops and cultured for further incubation. On day 3, embryo transfer was performed with grade 1 and 2 embryos. Monolayers for co-culture of embryos were prepared by plating $1{\times}10^5$ cumulus cells/ml in 10ul drop of TCM-199 + 10% FF or m-TALP + 5% FF + 5% FCS media 24 h prior to the onset of co-culture. Development to 4 to 16 cell stage was observed at 70x magnification following two days of incubation. Pregnancy was confirmed by detecting increasing serum ${\beta}$-hCG concentrations for 11 days following embryo transfer. Data were analyzed by ${\chi}^2$-test. Oocytes from 244 IVF-ET cycles were randomized. The number of cycles and mean age of patients were 97 and 147, 31.3 yrs and 31.2 yrs for TCM-199 (control) and m-TALP groups, respectively. The mean number of retrieved oocytes/cycle, fertilization rates, number of embryos transferred/ET and pregnancy rates were 11.1 and 10.3, 65.1% and 67.3%, 4.1 and 4.7, 28.9% and 43.8% for TCM-199 and m-TALP groups, respectively. Differences in the pregnancy rates were found between control and m-TALP groups (p<0.05). The pregnancy rate of patients divided according to maternal age groups of ${\leq}30$, 31-35, $36{\leq}$ were 44.4% and 49.0%, 26.1% and 41.3%, 29.2% and 41.2% for control and m-TALP groups, respectively. These data indicate that culture of human embryos in glucose/phosphate-free m-TALP medium improves pregnancy rates.

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Performance Characteristics of Organic Rankine Cycle Using Medium Temperature Waste Heat with Different Working Fluids (중온 배기열을 이용한 유기랭킨사이클 작동유체별 성능특성)

  • Kwon, Dong-Uk;Heo, Ki-Moo;Yoon, Sung-Hoon;Moon, Yoon-Jae;Yoo, Ho-Sun;Lee, Jae-Heon
    • Plant Journal
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    • v.10 no.2
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    • pp.38-47
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    • 2014
  • Renewable Portfolio Standards was introduced into the system in Korea in 2012. Interest in the unutilized and renewable energy sources is increasing. and these being actively investigated. An organic rankine cycle has emerged as an alternative in order to take advantage of bio-gas engine heat of sewage treatment plants whose capacity is 1500 kW. The organic rankine cycle power system was simulated by a simulator which is a commercial program of power plant design and performance analysis. The biogas engine is operated by $460^{\circ}C$ and 2.7 kg/s flow rate in the sewage treatment plant. Working fluids(R-601a, R-123, R-245fa) are selected to use in ORC power system in this temperature range. It was the isopentane that is the best performance among three working fluids. It could be obtained net power of 163.1 kW and efficiency of 13.66% from isopentane in the simulation.

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The Effects of Strategy of enhanced Metacognition on the Improvement of Creative Problem Solving Skills (메타인지 강화 전략이 창의적 문제 해결력 신장에 미치는 효과)

  • Song, Ju-yeon;Park, Ji-eun
    • Journal of Digital Convergence
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    • v.15 no.7
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    • pp.1-12
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    • 2017
  • The purpose of the study was to develop a teaching strategy using metacognition and to investigate its effects on enhancing students' creative problem solving skills (i.e. creative thinking skills and critical thinking skills), metacognitive skills. With reference to previous studies, the researcher developed self-questionnaire to enhance metacognition. To achieve this aim, a learning strategy enhancing metacognition was developed and applied to design a creative problem solving instruction program. The strategy was implemented to university students over 9 weeks. The same test was used in two groups. To analyze the data statistically, ANCOVA was used. Results indicated that the experimental group presented statistically meaningful improvement in creative thinking skills, especially identifying a problem, making hypothesis, and controlling of variables(p<.05). Also, the strategy contributed to improve critical thinking skills, especially in inquiry process of recognizing problems, making hypothesis(p<.05). In addition, this strategy also helped students' metacognitive skills(p<.05). It was effective to improve thinking skills. It will contribute to improve convergence thinking skills.

Evaluation of Citizens' Perception on the Utilization of Children's Parks for the Elderly (고령층을 위한 어린이공원의 활용방안에 대한 시민의식평가)

  • Lee, Kyong-bok;Hong, Kwang-Pyo;LEE, Hyukjae
    • The Journal of the Convergence on Culture Technology
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    • v.6 no.4
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    • pp.507-515
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    • 2020
  • The children's park, which was created uniformly during the industrialization period, is less utilized and is mainly used by the elderly during the day. In addition, sports facilities and rest facilities for the elderly are being installed, damaging the essence of children's parks. The main purpose of this study was to present the creation of a children's park that was appropriate to its essence and the utilization plan for the elderly. In this study, we conduct a survey to identify citizens' perception of children's parks and found that the opinions of children and the elderly were generally different. Children want to change and enjoy various games, while older people want to enjoy various programs while maintaining the status quo. As above, children do not dislike using the park with the elderly, but hope to create a separate park if possible. Meanwhile, the elderly want to renovate the current children's park and continue to use it. Therefore, in the future, some areas of children's parks will be created for the elderly or the entire area will be changed into small parks for the elderly, considering the location characteristics and population distribution of children's parks. In addition, the government should prepare measures for the introduction of programs for the elderly or maintenance using the elderly.

Effects of Philanthropy Education on Elementary School Students in Korea : Analysis Using a Multiple Convergence Model (나눔교육을 통한 아동의 변화 연구: Multiple Convergence Model의 적용)

  • Kang, Chul-Hee;Kim, Mi-Ok;Lee, Jong-Eun;Lee, Kyoung-Eun
    • Korean Journal of Social Welfare
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    • v.59 no.4
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    • pp.5-34
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    • 2007
  • This study explores the effects of philanthropy education for elementary school students by using a mixed method. To examine the effects of philanthropy education, two different approaches in research methods are conducted with different data collected from different target groups on the same phenomenon: a) experimental designs to analyze students' change(prosocial behaviors) by philanthropy education program performed in a summer camp(43 participants) and elementary schools(162 students); and b) qualitative analysis on students' changes in perceptual, attitudinal, and behavioral aspects by students' diary and memorandum(66 participants) and intensive interviews with teachers(5 teachers) and parents(4 mothers). The analysis of both quantitative and qualitative results shows that philanthropy education has effects on students' changes in diverse aspects including prosocial behavior. First, the results of quantitative analysis show that in every component of the prosocial behavior such as helping, being kind, empathizing, sharing, protecting, and cooperating, students have positive changes after philanthropy education. Such changes are statistically significant as well. Second, the results of qualitative analysis show that students after having philanthropy education display positive changes in diverse aspects. Particularly, the quantitative results are converged with the qualitative results from students, parents, and teachers. On the other hand, unique finding from qualitative analysis is that students after having philanthropy education can have fundamental changes in their personality. Such a change is commonly confirmed by students, parents, and teachers. This study makes it possible to compare results or to validate, confirm, or corroborate quantitative results with qualitative findings on the effects of philanthropy education for students.

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A Study on the Improvement of Teaching Competence of Pre-service Science Teachers based on the Teaching Evaluation and Reflective Journal Writings on Science Class (수업 평가와 반성 저널쓰기를 통한 예비 과학교사들의 수업 수행 능력 개선에 대한 연구)

  • Kim, Hyun-Jung;Hong, Hun-Gi;Jeon, Hwa-Young
    • Journal of The Korean Association For Science Education
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    • v.30 no.6
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    • pp.836-849
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    • 2010
  • The purpose of this study is to analyze changes of competency observed in teaching of pre-service science teachers through the teaching evaluation and reflective journal writings on science class during the period of student-teaching at high school. To do this, we videotaped all the science classes of six pre-service teachers participating in this study, evaluated their class teachings, and collected moving video clips recorded in their classes, reflective journals, interviews, instructional materials, and teaching evaluation they have provided. From the "Standards for teaching evaluation of science instruction" developed by Korea Education Curriculum and Assessment, sixteen evaluation elements were selected and used for the analysis. According to our results, all preservice teachers show improvement of teaching performance in most of the class evaluation elements as the number of science classes increases. They presented the lowest improvement in the 'to design meaningful learning program,' which was one of the sixteen elements. However, there are substantial individual differences in the pre-service teachers' teaching competence on each evaluation element. Although they thought that 'understanding of scientific concepts' is the most important part of a science class in the beginning of student-teaching training, they showed changes in recognition that 'interaction and respect' and 'managing student behaviors' are also important in the end. They have recognized that writing a reflective journal, based on the video clips recorded in class and teaching evaluation, helps improve their teaching competency. In addition, improvement in teaching competency has influence upon career-orientation towards the school teacher in the future.

Development and Effect of the Feeding Protocol for Preterm Infants (미숙아의 수유 프로토콜 개발 및 적용)

  • Lee, Jae-Young;Son, Hyun-Mi;Park, Kyung-Hee
    • Child Health Nursing Research
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    • v.20 no.1
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    • pp.20-29
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    • 2014
  • Purpose: The purpose of this study was to develop a feeding protocol for premature infants and to evaluate the effects of protocol. Methods: The feeding protocol was developed through a literature review and discussions of an expert group. The developed feeding protocol was tested with 85 preterm infants in one neonatal intensive care unit in B city. A non-equivalent control group non-synchronized design was used. Data were collected from January 1 to April 30, 2013 for the control group and from June 1 to September 30, 2013 for the experimental group. The experimental group (n=38) received the feeding protocol, whereas the control group (n=47) had routine feeding care. Collected data were analyzed by t-test and -test using SPSS/WIN version 18.0. Results: First feeding time (t=2.22, p=.029) and full enteral feeding time (t=2.28, p=.026) were significantly decreased in the experimental group compared to the control group. There was no difference in incidence of complications (p>.05). Also no significant differences in weight reduction rate between the two groups were observed at the 7th postnatal day (t=-1.23, p=.222). Conclusion: The results indicate that the feeding protocol for preterm infants is effective in decreasing first feeding time and full enteral feeding time.

Development of Fermented Beverage Using the Sea Tangle Extract, and Quality Characteristics Thereof (다시마추출액을 이용한 발효음료개발 및 품질특성)

  • Kim, Mi-Lim;Choi, Mi-Ae;Jeong, Ji-Suk
    • Food Science and Preservation
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    • v.15 no.1
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    • pp.21-29
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    • 2008
  • This study investigated the fermentation and quality characteristics of a fermented beverage, prepared by semi-anaerobic culture, using sea tangle extract. A central composit design using alcohol(0, 0.5, 1.0, 1.5, 2.0% [all v/v] ), sugar(0, 5, 10, 15, 20% [all w/v] ) and $65^{\circ}Brix$ citrus juice(0, 1.0, 2.0, 3.0, 4.0 % [all v/v] ) was used to find the optimal mix for fermentation. Sensory characteristics, such as color, flavor, taste, sweetness, saltiness, sourness and overall quality, were measured using a response surface methodology computer program. The optimal conditions that produced the highest acidity of 0.94 were 2.0 % ethanol, 10.17 % sucrose and 1.99 % citrus juice. The optimal conditions that produced gel 20.13 nun in thickness were 1.98% alcohol, 10.94% sucrose and 1.62% citrus juice. The overall optimal conditions that satisfied all the sensory requirements for a sea tangle beverage were 1.0% alcohol, 10.0% sucrose and 4.05% citrus juice.

Current Status and Direction for Future Development of Evidence-based Nursing in Korea (국내 근거기반간호의 현황과 발전 방향)

  • Choe, Myoung-Ae;Bang, Kyung-Sook;Park, Yeon-Hwan;Kang, Hyun-Ju
    • Perspectives in Nursing Science
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    • v.8 no.2
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    • pp.129-138
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    • 2011
  • Purpose: The purpose of this study was to identify the current status of evidence-based research, education, and practice, and to suggest a directions for the future development of evidence-based nursing. Methods: To examine the current status of evidence-based nursing research, experimental research among studies published in the Journal of Korean Academy of Nursing from 2008 to 2010 were analyzed. We suggested a direction for the future development of evidence-based research based on the analysis and literature reviews. We also suggested a direction for the future development of evidence-based education and practice based on literature reviews. Results: The results showed that designs and methods of studies were insufficient to use evidences derived from the studies in terms of evidence-based research, and experimental studies consistent with themes were found to be deficient. In the future, the methods and rationale for the design of experimental studies need to be clearer In addition, a test for intervention effects through repetitive studies and a connection between the intervention effects and a protocol for clinical practice will be required. In terms of evidence-based education, curriculum revision and development of teaching methods including contents related to evidence-based practice and research methodology in undergraduate and graduate programs will be required. Evidence-based practice in Korea was less actively done than with that of foreign countries. Some large hospitals have recently attempted systemic activities to promote evidence-based nursing practice in clinical settings. To activate evidence-based practice, the perception of nurses for evidence-based practice needs to be changed and support for education and administration of the program is required. Also, evidence-based practice guidelines, protocols, and assessment tools need to be developed. Conclusion: Evidence-based nursing in Korea is in the process of evolving. To realize evidence-based nursing, we need to develop nursing science based on evidences of closer communication and cooperation in terms of nursing research, education, and practice.

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Stress Concentration Ratio of GCP Depending on the Mixing Ratio of Crushed Stone and Sand (GCP의 쇄석과 모래의 배합비 별 응력분담비)

  • Na, Seung-Ju;Kim, Min-Seok;Park, Kyung-Ho;Kim, Daehyeon
    • Journal of the Korean Geotechnical Society
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    • v.32 no.9
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    • pp.37-50
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    • 2016
  • Gravel compaction pile (GCP) is widely used as it increases the bearing capacity of soft ground and reduces the consolidation settlement. Stress concentration ratio for GCP design is dependent on the area replacement, surcharge pressure and depth. However, a range of stress concentration ratio obtained through field, laboratory experiments and numerical analysis is large. Little study has been done on the stress concentration ratio for the mixing ratio of gravel and sand. The main objective of the study is to evaluate the stress concentration ratio for both area replacement ratio and mixing ratio through literature review and numerical analysis. Numerical analysis using the finite element program ABAQUS 6.12-4 has been performed for the composite ground with GCP. The excess pore water pressure and stress concentration ratio of composite ground have been analyzed for both the area replacement ratio and the mixing ratio. Based on the previous research results, a range of stress concentration ratio obtained from the field tests, laboratory tests, numerical analysis on the GCP studies is found to be 1.7-3.2, 2.0-7.5 and 2.0-6.5, respectively. Based on the numerical analysis results, as the area replacement ratio increases, the stress concentration ratio increases up to 30% and then decreases at 40%. Also, the stress concentration ratio tends to increase up to 70:30 and then to decrease after 60:40.